| 301. | "GHOST of the YEAR" by Gooseworx Reaction! | 4,645 | |
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| 302. | "Animation vs. Minecraft Shorts” Ep. 1-3 by Alan Becker Reaction! | 4,641 | | Minecraft
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| 303. | "Super Vampire" by Batman4014 Reaction! | 4,612 | |
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| 304. | "skibidi toilet - season 22" by DaFuq!?Boom! Reaction! | 4,603 | |
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| 305. | "Nightmare VS Dream" by EthanAnimatez Reaction! | 4,566 | |
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| 306. | "Suction Cup Man" 1-4 by Piemations Reaction! | 4,512 | |
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| 307. | "Animation vs. Minecraft Shorts" Ep. 4-6 by Alan Becker Reaction! | 4,504 | | Minecraft
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| 308. | "skibidi toilet" Ep. 50-52 by DaFuq!?Boom! Reaction! | 4,493 | |
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| 309. | "Being Not Straight" by Jaiden Animations Reaction! | 4,461 | |
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| 310. | "Purpose" by ZNathan Animations Reaction! | 4,451 | |
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| 311. | "i became an italian farmer" by Ice Cream Sandwich Reaction! | 4,415 | |
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| 312. | You Are a Planet | 4,411 | |
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| 313. | "Feeling Good" by EthanAnimatez Reaction! | 4,389 | |
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| 314. | "The Fallen Guardians - A Liberted Soul" (Not Finale) by Animations Insider Reaction! | 4,381 | |
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| 315. | "...And We'll Do it Again" by Kurzgesagt Reaction! | 4,374 | |
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| 316. | "The Fallen Guardians - The Breath of Freedom" by Animations Insider Reaction! | 4,345 | |
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| 317. | "Misery was" by exurb1a Reaction! | 4,332 | |
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| 318. | "The Horror of the Slaver Ant" by Kurzgesagt Reaction! | 4,320 | |
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| 319. | So Handsome | 4,319 | |
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| 320. | "skibidi toilet" Ep. 58-59 by DaFuq!?Boom! Reaction! | 4,294 | |
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| 321. | "WHY WE LOSE" by Lyzander Mixers Reaction! | 4,261 | | Minecraft
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| 322. | "The Day Of The Departed Episode 7" Part 2 by Shadow Creeper Reaction! | 4,260 | Show |
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| 323. | That Doesn't Seem Fair | 4,242 | |
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| 324. | "The Nightmares And Dreams" Ep. 1-3 by Tom Animator Reaction! | 4,236 | |
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| 325. | The Murder of Potato Girl - Attack on Titan 2 | 4,231 | | Attack on Titan 2
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| 326. | "adhd" by Ice Cream Sandwich Reaction! | 4,214 | |
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| 327. | "Inspired" by GenVeraAnimations Reaction! | 4,172 | |
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| 328. | "The Deadliest Virus on Earth" by Kurzgesagt Reaction! | 4,171 | |
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| 329. | "Never Ending Winter" by Shadow Creeper Reaction! | 4,155 | |
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| 330. | "The Moon is a Door to Forever" by exurb1a Reaction! | 4,135 | |
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| 331. | "How to Be Correct About Everything All the Time" by exurb1a Reaction! | 4,087 | Guide |
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| 332. | MURDER DRONES - Episode 7: Mass Destruction | 4,078 | Show | Mass Destruction
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| 333. | "The Largest Star in the Universe" by Kurzgesagt Reaction! | 4,066 | |
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| 334. | "You Will Never See Me Coming" by ZNathan Animations Reaction! | 4,044 | | Minecraft
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| 335. | "Something's Missing" by Deformed Lunchbox Reaction! | 4,026 | |
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| 336. | "Animation vs. Minecraft Shorts" Ep. 13-15 by Alan Becker Reaction! | 3,993 | | Minecraft
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| 337. | "ZOMBIE APOCALYPSE: THE LAST STAND" by Squared Media Reaction! | 3,978 | |
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| 338. | "INFINITY" by Lyzander Mixers Reaction! | 3,960 | | Minecraft
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| 339. | "Insane Childhood Punishments" by Tabbes Reaction! | 3,909 | |
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| 340. | "super powers" by Ice Cream Sandwich Reaction! | 3,898 | |
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| 341. | "Animation vs. Minecraft Shorts" Ep. 7-9 by Alan Becker Reaction! | 3,858 | | Minecraft
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| 342. | "My Thoughts on Reality Shifting" by TheOdd1sOut Reaction! | 3,834 | |
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| 343. | "Ready For Anything" by Batman4014 Reaction! | 3,820 | |
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| 344. | Become A Member! | 3,807 | |
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| 345. | "Goodbye" by Shadow Creeper Reaction! | 3,795 | | Minecraft
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| 346. | Please Open! Gift Inside! | 3,794 | |
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| 347. | "The Aftermath" by Storm Animations Reaction! | 3,778 | |
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| 348. | "Oblivion" by EthanAnimatez Reaction! | 3,729 | |
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| 349. | "Animation vs. Minecraft Shorts" Ep. 10-12 by Alan Becker Reaction! | 3,711 | | Minecraft
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| 350. | "The Day Of The Departed Episode 7" Part 1 by Shadow Creeper Reaction! | 3,680 | Show |
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| 351. | "Like Yesterday" by JeffVix Reaction! | 3,675 | |
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| 352. | "Annoying Villagers 65" by MrFudgeMonkeyz Reaction! | 3,667 | |
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| 353. | Sad For Him | 3,666 | |
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| 354. | "The Nightmares And Dreams" Ep. 4-6 by Tom Animator Reaction! | 3,646 | |
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| 355. | "The Nightmares And Dreams" Ep. 7-11 by Tom Animator Reaction! | 3,618 | |
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| 356. | By all means...finish your drink | 3,576 | | Cyberpunk 2077
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| 357. | "The AETHER Rescue of Herobrine" by Squared Media Reaction! | 3,575 | |
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| 358. | "How to Win an Interstellar War" by Kurzgesagt Reaction! | 3,554 | Guide |
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| 359. | "The Epic of Serina | Part I" by Curious Archive Reaction! | 3,523 | |
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| 360. | "Vision" by ZNathan Animations Reaction! | 3,506 | |
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| 361. | It’s Just A Dream Away | 3,489 | |
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| 362. | "The Virus" by Alan Becker Reaction! | 3,475 | |
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| 363. | That’s Gotta Be a Record | 3,449 | | Spider-Man 2
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| 364. | "How NOT to Make an Electric Guitar" by ElectroBOOM Reaction! | 3,447 | |
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| 365. | "My Thoughts on Bluey" by TheOdd1sOut Reaction! | 3,444 | |
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| 366. | "Walls" by Shadow Creeper Reaction! | 3,443 | |
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| 367. | "There's No Such Thing As Orange" by exurb1a Reaction! | 3,417 | |
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| 368. | "GIVE ME LIFE" by Jeffvix Reaction! | 3,407 | |
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| 369. | "The Game of the Red Eye" by Snarled Reaction! | 3,406 | |
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| 370. | "The Rolling Giant" by Kane Pixels Reaction! | 3,404 | |
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| 371. | "Mario & Luigi: Super Anime Brothers" by mashed Reaction! | 3,397 | |
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| 372. | "WITHER STORM WAR" by Squared Media Reaction! | 3,357 | |
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| 373. | "skibidi toilet" Ep. 53-55 by DaFuq!?Boom! Reaction! | 3,354 | |
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| 374. | "As We Fall" by JeffVix Reaction! | 3,333 | |
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| 375. | "Falling Apart" by Shadow Creeper Reaction! | 3,328 | |
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| 376. | "What if You Become Invisible for 24 Hours?" by Meet Arnold Reaction! | 3,323 | |
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| 377. | "The Fallen Guardians - New Nightmares" by Animations Insider Reaction! | 3,317 | |
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| 378. | Preparing for Livestreams be Like… | 3,308 | |
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| 379. | "This is Where it Ends" by JeffVix Reaction! | 3,292 | |
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| 380. | "Scams That Should be Illegal" by TheOdd1sOut Reaction! | 3,272 | |
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| 381. | "LOST" by Animations Insider Reaction! | 3,264 | |
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| 382. | "You Are Not Where You Think You Are" by Kurzgesagt Reaction! | 3,253 | |
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| 383. | "I Don't Want the Truth" by JeffVix Reaction! | 3,252 | |
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| 384. | "Animator vs. Animation" Ep. 1-3 by Alan Becker Reaction! | 3,197 | |
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| 385. | "The Fallen Guardians - The Revenge of the Brothers" by Animations Insider Reaction! | 3,182 | |
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| 386. | "Before You Go" by Blocky G8mer224 Reaction! | 3,168 | |
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| 387. | IT’S SUPERMAN! | 3,168 | | Fortnite
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| 388. | The Best Advice | 3,154 | |
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| 389. | "BEES RAP" by Squared Media Reaction! | 3,144 | | Minecraft
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| 390. | "Dream VS MrBeast" Trilogy by krefix Reaction! | 3,135 | |
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| 391. | "Rise of Vampire" by Batman4014 Reaction! | 3,134 | |
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| 392. | "My Time at "Camp Operetta" by Jaiden Animations Reaction! | 3,122 | |
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| 393. | "My Weird Trip to the UK" by Jaiden Animations Reaction! | 3,116 | |
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| 394. | "RISE" by SlyBoyMaster Reaction! | 3,103 | |
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| 395. | "Desert Arena: SURVIVAL" by Squared Media Reaction! | 3,089 | |
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| 396. | "HEROBRINE'S LIFE" by Redstone Records Reaction! | 3,084 | | Minecraft
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| 397. | "What Are You Doing With Your Life? The Tail End" by Kurzgesagt Reaction! | 3,081 | |
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| 398. | "Genocide Bingo" by exurb1a Reaction! | 3,074 | |
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| 399. | Tooted The Horn Early | 3,074 | |
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| 400. | "AFTON - Full Movie" by 3A Display Reaction! | 3,072 | |
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