| 301. | Certifiably Deadly! - The Binding of Isaac: Repentance #185 | 4,622 | | The Binding of Isaac: Rebirth
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| 302. | SpiderManMemeIsaac.EXE | 4,618 | | The Binding of Isaac: Rebirth
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| 303. | WE GOT DEAD GOD! (Ft. Keelvin)- [637/637] Secrets | 4,615 | | The Binding of Isaac: Rebirth
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| 304. | The Glitched Item to Rule Them All! - The Binding of Isaac: Repentance #197 | 4,591 | | The Binding of Isaac: Rebirth
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| 305. | Beating Mother as Lost Is TOO Stressful! | 4,569 | | The Binding of Isaac: Rebirth
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| 306. | Almond Milk Rampage! - The Binding of Isaac: Repentance #65 | 4,569 | | The Binding of Isaac: Rebirth
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| 307. | Getting To Close With The Devil! - The Binding of Isaac: Repentance #77 | 4,568 | | The Binding of Isaac: Rebirth
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| 308. | Tainted Forgotten Makes Mega Satan TOO Easy... | 4,534 | | The Binding of Isaac: Rebirth
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| 309. | Ultimate Spindown Dice Plays! - The Binding of Isaac: Repentance #31 | 4,510 | | The Binding of Isaac: Rebirth
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| 310. | Spinny Death of Ow‽ - The Binding of Isaac: Repentance #49 | 4,478 | | The Binding of Isaac: Rebirth
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| 311. | Too Broke for Sacred Heart... | 4,463 | | The Binding of Isaac: Rebirth
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| 312. | Craziest First Floor Spindown! - The Binding of Isaac: Repentance #69 | 4,453 | | The Binding of Isaac: Rebirth
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| 313. | Sacred Start! - The Binding of Isaac: Repentance #103 | 4,452 | | The Binding of Isaac: Rebirth
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| 314. | Luckiest Almond Milk Items! - The Binding of Isaac: Repentance #93 | 4,452 | | The Binding of Isaac: Rebirth
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| 315. | The Return of the Eden Streak - The Binding of Isaac: Repentance #1 | 4,448 | | The Binding of Isaac: Rebirth
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| 316. | Best ACTUAL Synergy! - The Binding of Isaac: Repentance #96 | 4,444 | | The Binding of Isaac: Rebirth
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| 317. | Incubus + Lil Clot + Fate's Reward Is The REAL Perfect Trio! - The Binding of Isaac: Repentance #33 | 4,440 | | The Binding of Isaac: Rebirth
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| 318. | Three Deadliest Items! - The Binding of Isaac: Repentance #109 | 4,420 | | The Binding of Isaac: Rebirth
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| 319. | Teleporting to Victory! | 4,419 | | The Binding of Isaac: Rebirth
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| 320. | Staying Clear of Alt path! - The Binding of Isaac: Repentance #54 | 4,340 | | The Binding of Isaac: Rebirth
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| 321. | Most Surprisingly Overpowered Synergy In Repentance! - The Binding of Isaac: Repentance #32 | 4,326 | | The Binding of Isaac: Rebirth
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| 322. | THE BABY MAGNET! - The Binding of Isaac: Repentance #117 | 4,309 | | The Binding of Isaac: Rebirth
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| 323. | Delirium Destroyer! - The Binding of Isaac: Repentance #110 | 4,303 | | The Binding of Isaac: Rebirth
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| 324. | How To Make Bad Items GREAT! - The Binding of Isaac: Repentance #90 | 4,288 | Guide | The Binding of Isaac: Rebirth
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| 325. | DANGEROUS DUALITY! - The Binding of Isaac: Repentance #196 | 4,258 | | The Binding of Isaac: Rebirth
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| 326. | Do Decap Attack And Isaac's Heart Make You Unkillable? - The Binding of Isaac: Repentance #76 | 4,249 | | The Binding of Isaac: Rebirth
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| 327. | Using Teleportation to the MAX! - The Binding of Isaac: Repentance #10 | 4,245 | | The Binding of Isaac: Rebirth
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| 328. | DESTROYING Frames and Breaking Games! - The Binding of Isaac: Repentance #90 | 4,184 | | The Binding of Isaac: Rebirth
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| 329. | Ultimate Brimstone and Sacred Heart Greed Run! - The Binding of Isaac #46 | 4,155 | | The Binding of Isaac: Rebirth
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| 330. | Full Auto Monstro's Lung! - The Binding of Isaac: Repentance #86 | 4,142 | | The Binding of Isaac: Rebirth
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| 331. | RARE Double Item Spawn In Normal Room! | 4,124 | | The Binding of Isaac: Rebirth
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| 332. | Infinite Damage! - The Binding of Isaac: Repentance #122 | 4,117 | | The Binding of Isaac: Rebirth
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| 333. | BD1P Takes Control of Greed (GONE SEXUAL!) - The Binding of Isaac: Repentance | 4,111 | | The Binding of Isaac: Rebirth
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| 334. | Delirious Damocles! - The Binding of Isaac: Repentance #121 | 4,082 | | The Binding of Isaac: Rebirth
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| 335. | Ultimate Damage! - The Binding of Isaac: Repentance #113 | 4,079 | | The Binding of Isaac: Rebirth
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| 336. | Machine Shotgun Combo! - The Binding of Isaac: Repentance #202 | 4,078 | | The Binding of Isaac: Rebirth
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| 337. | The Last Run - The Binding of Isaac: Repentance #106 | 4,066 | | The Binding of Isaac: Rebirth
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| 338. | ONE YEAR OF EDEN STREAK! - The Binding of Isaac: Repentance | 4,049 | | The Binding of Isaac: Rebirth
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| 339. | Mom's Knife Is WAY Too Strong With Quadshot! - The Binding of Isaac: Repentance #99 | 4,043 | | The Binding of Isaac: Rebirth
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| 340. | The Greatest Run! - The Binding of Isaac: Repentance #162 | 4,003 | | The Binding of Isaac: Rebirth
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| 341. | Soy-Section Is INSANE! - The Binding of Isaac: Repentance #74 | 3,999 | | The Binding of Isaac: Rebirth
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| 342. | STOP GIVING ME THE SAME ITEMS, ED! - The Binding of Isaac: Repentance #73 | 3,995 | | The Binding of Isaac: Rebirth
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| 343. | The Sacredest Heart! - The Binding of Isaac: Repentance #73 | 3,992 | | The Binding of Isaac: Rebirth
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| 344. | The Mush Incident! - The Binding of Isaac: Repentance #204 | 3,980 | | The Binding of Isaac: Rebirth
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| 345. | An Absolute Laser Disaster! - The Binding of Isaac: Repentance #85 | 3,945 | | The Binding of Isaac: Rebirth
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| 346. | HOLY HOMING! - The Binding of Isaac: Repentance #176 | 3,945 | | The Binding of Isaac: Rebirth
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| 347. | The Best Active Item That No One Talks About... - The Binding of Isaac: Repentance #93 | 3,940 | | The Binding of Isaac: Rebirth
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| 348. | All The Angel Deals, but None of the Good Ones! - The Binding of Isaac: Repentance #79 | 3,934 | | The Binding of Isaac: Rebirth
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| 349. | New Save File to Tainted Character Speedrun - 12 HOUR SPECIAL LIVESTREAM | 3,929 | | The Binding of Isaac: Rebirth
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| 350. | Hot Potato Might Be The HARDEST Repentance Challenge! - The Binding of Isaac: Repentance | 3,926 | | The Binding of Isaac: Rebirth
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| 351. | Cheating or Luck?! | 3,924 | | The Binding of Isaac: Rebirth
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| 352. | Beating Mom's Heart 11 Times in ONE Run! (Speedrunning) - The Binding of Isaac: Repentance | 3,924 | | The Binding of Isaac: Rebirth
|
| 353. | How To Get Hush's Continuum Tears (Tiny Planet + Continuum) | 3,898 | Guide | The Binding of Isaac: Rebirth
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| 354. | Thunderstorm Combo! - The Binding of Isaac: Repentance #182 | 3,893 | | The Binding of Isaac: Rebirth
|
| 355. | The Dangers of Starting with Chaos! - The Binding of Isaac: Repentance #84 | 3,887 | | The Binding of Isaac: Rebirth
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| 356. | Mega Section! - The Binding of Isaac: Repentance #206 | 3,870 | | The Binding of Isaac: Rebirth
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| 357. | The Godly Waffle Iron! - The Binding of Isaac: Repentance #7 | 3,861 | | The Binding of Isaac: Rebirth
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| 358. | Napalm Thrower! - The Binding of Isaac: Repentance #138 | 3,849 | | The Binding of Isaac: Rebirth
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| 359. | Soy Synth! - The Binding of Isaac: Repentance #190 | 3,832 | | The Binding of Isaac: Rebirth
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| 360. | Trisagion Can Get WAY Out Of Hand! - The Binding of Isaac: Repentance #97 | 3,815 | | The Binding of Isaac: Rebirth
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| 361. | IPESTONE TECHNIQUE! - The Binding of Isaac: Repentance #186 | 3,790 | | The Binding of Isaac: Rebirth
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| 362. | Most Dangerous Bomb Combo! - The Binding of Isaac: Repentance #178 | 3,775 | | The Binding of Isaac: Rebirth
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| 363. | How To See What Items You Have Not Picked Up! - The Binding Of Isaac | 3,750 | Guide | The Binding of Isaac: Rebirth
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| 364. | Teleporting To EVERY Devil Deal! - The Binding of Isaac: Repentance #66 | 3,721 | | The Binding of Isaac: Rebirth
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| 365. | The Best Average Run! - The Binding of Isaac: Repentance #120 | 3,718 | | The Binding of Isaac: Rebirth
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| 366. | Crazy Damage from Three Items! - The Binding of Isaac: Repentance #25 | 3,699 | | The Binding of Isaac: Rebirth
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| 367. | QUADTOSIS! - The Binding of Isaac: Repentance #216 | 3,698 | | The Binding of Isaac: Rebirth
|
| 368. | Insane Damage at a Cost! - The Binding of Isaac: Repentance #26 | 3,695 | | The Binding of Isaac: Rebirth
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| 369. | Most Satisfying High Damage Run! - The Binding of Isaac: Repentance #168 | 3,689 | | The Binding of Isaac: Rebirth
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| 370. | The Death Strat? - The Binding of Isaac: Repentance #119 | 3,687 | | The Binding of Isaac: Rebirth
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| 371. | Isaac's Heart and Salvation Are My New Favorite Items?! - The Binding of Isaac: Repentance #11 | 3,660 | | The Binding of Isaac: Rebirth
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| 372. | Blood Oath Got Me Killed With AMAZONG Build! - The Binding of Isaac: Repentance #70 | 3,651 | | The Binding of Isaac: Rebirth
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| 373. | Static Charge Combo! - The Binding of Isaac: Repentance #99 | 3,650 | | The Binding of Isaac: Rebirth
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| 374. | Spin To Win And Isaac's Heart Is INSANE! - The Binding of Isaac: Repentance #30 | 3,634 | | The Binding of Isaac: Rebirth
|
| 375. | World's Fastest Guppy! - The Binding of Isaac: Repentance #91 | 3,632 | | The Binding of Isaac: Rebirth
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| 376. | Tainted Jacob WITHOUT CHEESING HIM! - The Binding of Isaac: Repentance | 3,630 | | The Binding of Isaac: Rebirth
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| 377. | Lots of Luck and Curses! - The Binding of Isaac: Repentance #23 | 3,613 | | The Binding of Isaac: Rebirth
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| 378. | The Echo Chamber Experience | 3,587 | | The Binding of Isaac: Rebirth
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| 379. | Delirium Was A Mistake! - The Binding of Isaac: Repentance #28 | 3,574 | | The Binding of Isaac: Rebirth
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| 380. | Surprisingly Bad Sacred Heart Run! - The Binding of Isaac: Repentance #92 | 3,564 | | The Binding of Isaac: Rebirth
|
| 381. | New Character Can't Shoot Tears!? - The Hollow! | 3,547 | | The Binding of Isaac: Rebirth
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| 382. | Seven Guppy Items in ONE RUN! - The Binding of Isaac: Repentance #97 | 3,534 | | The Binding of Isaac: Rebirth
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| 383. | Boss Deleter Combo! - The Binding of Isaac: Repentance #123 | 3,533 | | The Binding of Isaac: Rebirth
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| 384. | This is THE BEST Trinket in the Game! - The Binding of Isaac: Repentance #83 | 3,531 | | The Binding of Isaac: Rebirth
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| 385. | Tear Splitting Never Felt So Sweet! - The Binding of Isaac: Repentance #102 | 3,530 | | The Binding of Isaac: Rebirth
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| 386. | God Bomb Combo! - The Binding of Isaac: Repentance #189 | 3,528 | | The Binding of Isaac: Rebirth
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| 387. | Minecraft Crafting in Isaac is INSANE! - The Binding of Isaac: Repentance #13 | 3,515 | | The Binding of Isaac: Rebirth
|
| 388. | POLYPHEM-X! - The Binding of Isaac: Repentance #166 | 3,515 | | The Binding of Isaac: Rebirth
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| 389. | FLIPTASTROPHY! - The Binding of Isaac: Repentance #106 | 3,509 | | The Binding of Isaac: Rebirth
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| 390. | The Tale of Rock Bottom! - The Binding of Isaac: Repentance #58 | 3,497 | | The Binding of Isaac: Rebirth
|
| 391. | I Saved Isaac's Heart From Death! - The Binding of Isaac: Repentance | 3,495 | | The Binding of Isaac: Rebirth
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| 392. | How to Win with No Damage! - The Binding of Isaac: Repentance #95 | 3,494 | Guide | The Binding of Isaac: Rebirth
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| 393. | GOD BOTTOM! - The Binding of Isaac: Repentance #226 | 3,487 | | The Binding of Isaac: Rebirth
|
| 394. | Most Explosive Run! - The Binding of Isaac: Repentance #105 | 3,485 | | The Binding of Isaac: Rebirth
|
| 395. | The Glitched Crown Disaster! - The Binding of Isaac: Repentance #46 | 3,480 | | The Binding of Isaac: Rebirth
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| 396. | Milky Sword! - The Binding of Isaac: Repentance #187 | 3,474 | | The Binding of Isaac: Rebirth
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| 397. | The Unkillable Bomber! - The Binding of Isaac: Repentance #92 | 3,473 | | The Binding of Isaac: Rebirth
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| 398. | POV: You're Too Poor to Open the Arcade... | 3,458 | | The Binding of Isaac: Rebirth
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| 399. | Proving ALL the Haters Wrong... | 3,437 | | The Binding of Isaac: Rebirth
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| 400. | Chat Takes Away The BEST Items! (Twitch Reloaded) - The Binding of Isaac: Repentance | 3,421 | | The Binding of Isaac: Rebirth
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