| 2018-10-24 | #87: PonyORM: The most Pythonic ORM yet? | 56:30 | 704 | |
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| 2018-10-22 | #86: Python at StackOverflow | 1:10:21 | 188 | |
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| 2018-10-22 | #85: Parsing horrible things with Python | 59:47 | 151 | |
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| 2018-10-22 | #84: Are we failing to fund Python's core infrastructure? -- Talk Python To Me podcast | 1:05:28 | 53 | Show |
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| 2018-10-20 | #83: Python Videos on Demand at PyVideo -- Talk Python To Me podcast | 53:26 | 182 | Show |
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| 2018-10-20 | #82: Grokking Algorithms in Python -- Talk Python To Me podcast | 58:46 | 2,487 | Show |
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| 2018-10-19 | #81: Python and Machine Learning in Astronomy -- Talk Python To Me | 1:02:14 | 733 | |
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| 2018-07-30 | Course Trailer: Building data-driven web apps with Pyramid and SQLAlchemy | 9:37 | 3,712 | |
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| 2017-09-05 | Overview of the Talk Python Training course player | 2:05 | 1,100 | |
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| 2016-10-24 | Episode #80: TinyDB: A tiny document db written in Python | 47:00 | 2,329 | Show |
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| 2016-10-21 | Episode #79: Beeware Python Tools | 1:22:14 | 4,093 | Show |
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| 2016-10-20 | Episode #78: How I built an entire game and toolchain 100% in Python | 53:27 | 598 | Show |
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| 2016-10-20 | Episode #77: 20 Python Libraries You Aren't Using (But Should) | 1:16:57 | 2,692 | Show |
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| 2016-10-19 | Episode #76: Renewable Python | 54:10 | 381 | Show |
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| 2016-10-18 | Episode #75: Pythonic games at CheckIO | 55:27 | 462 | Show |
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| 2016-10-16 | Episode #74: Past, Present, and Future of IronPython | 50:49 | 703 | Show |
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| 2016-10-16 | Episode #73: Machine learning at the new Microsoft | 1:05:43 | 263 | Show |
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| 2016-10-16 | Episode #72: Fashion-driven open source software at Zalando | 1:01:18 | 170 | Show |
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| 2016-08-12 | Soft Skills for Python Developers - Talk Python To Me | 1:05:33 | 6,894 | |
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| 2016-08-12 | #70: Pythonic cover songs at Loudr | 1:01:39 | 134 | |
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| 2016-08-12 | #69: Write an Excellent Programming Blog | 57:42 | 2,009 | Vlog |
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| 2016-08-12 | #68: Crossing the streams with Podcast.__init__ | 1:02:21 | 99 | Show |
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| 2016-08-12 | #67: Property-based Testing with Hypothesis | 58:18 | 222 | |
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| 2016-08-12 | 66 faster python programs measure dont guess | 1:04:56 | 157 | |
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| 2016-07-04 | #65: Jump on the real-time web with RethinkDB | 59:23 | 444 | |
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| 2016-07-04 | #64: Inside the Python Package Index | 59:51 | 253 | |
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| 2016-07-04 | #63: Validating Python tests with mutation testing | 59:36 | 269 | |
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| 2016-06-21 | Course: Write Pythonic Code Like a Seasoned Developer | 2:10 | 634 | |
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| 2016-06-12 | #62: San Diego Technology Immersion Group Learns Python | 1:09:22 | 116 | Vlog |
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| 2016-06-12 | #61: Free software, free people | 54:18 | 163 | |
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| 2016-06-12 | #60: Scaling Python to 1000's of cores with Ufora | 1:07:28 | 132 | |
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| 2016-06-12 | #59 SageMath - Open source is ready to compete in the classroom | 59:24 | 323 | |
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| 2016-06-12 | #58 Create better Python programs with concurrency, libraries, and patterns | 54:52 | 355 | |
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| 2016-06-12 | #57: Python performance from the inside-out at Intel | 56:35 | 147 | |
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| 2016-06-12 | #56 Data Science from Scratch | 51:03 | 1,791 | |
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| 2016-04-21 | #55: Interview: How our engineering environments are killing diversity (and how we can fix it) | 1:01:41 | 179 | |
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| 2016-04-21 | #54: Enterprise Software with Python | 1:07:43 | 3,265 | |
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| 2016-04-08 | #53: Python in Visual Studio | 50:41 | 524 | |
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| 2016-04-08 | #52: EVE Online: MMO game powered by Python | 54:36 | 3,083 | | EVE Online
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| 2016-04-08 | #51: SigOpt: Optimizing Everything with Python | 37:05 | 332 | |
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| 2016-04-08 | #50: Web scraping at scale with Scrapy and ScrapingHub | 58:17 | 1,748 | |
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| 2016-04-08 | #49: Microsoft's JIT-based Python Project: Pyjion | 1:03:46 | 329 | |
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| 2016-04-08 | #48: Building Flask-based Web Apps | 49:09 | 681 | Show |
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| 2016-04-08 | #47: Python in Typeface and Font Development | 44:40 | 1,301 | |
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| 2016-04-08 | #46: Python in Movies and Entertainment | 57:13 | 143 | |
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| 2016-02-18 | Kickstarter: Python Jumpstart by Building 10 Apps [video course] | 5:39 | 875 | |
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| 2016-02-15 | #45: The Python Testing Column, Now a Thing | 58:50 | 147 | |
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| 2016-02-15 | #44: Project Jupyter and IPython | 1:00:12 | 205 | |
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| 2016-02-15 | #42: Python in Startups and Investing | 54:39 | 723 | |
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| 2016-02-15 | #43: Monitoring high performance Python apps at Opbeat | 39:34 | 266 | |
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| 2016-02-15 | Getting your first Python dev job (part 2) - Talk Python To Me episode | 52:18 | 2,086 | Show |
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| 2015-12-30 | #40: Top 10 Data Science Stories from 2015 | 59:20 | 346 | |
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| 2015-12-22 | Getting your first Python dev job (part 1) - Talk Python To Me episode | 50:44 | 36,872 | Show |
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| 2015-12-15 | #38: Continuous Integration and Delivery at Codeship | 1:02:51 | 187 | |
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| 2015-12-14 | #37: Python Cybersecurity and Penetration Testing | 1:04:03 | 6,069 | |
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| 2015-12-14 | #36: Python IDEs with the PyCharm team | 59:43 | 1,093 | |
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| 2015-12-14 | #35: Turbogears and the future of Python web frameworks | 1:01:16 | 1,919 | |
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| 2015-12-14 | #34 Continuum Scientific Python and The Business of Open Source | 59:52 | 102 | |
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| 2015-11-10 | Episode #33: OpenStack: Cloud computing built on Python | 56:38 | 455 | Show |
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| 2015-11-04 | Episode #32: PyPy.js - PyPy Python in Your Browser | 59:12 | 549 | Show |
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| 2015-10-27 | Episode #31: Machine Learning with Python and scikit-learn | 49:19 | 341 | Show |
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| 2015-10-27 | Episode #30: Python Community and Python at Dropbox | 46:54 | 920 | Show |
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| 2015-10-13 | Episode #29: Python at the Large Hadron Collider and CERN | 52:10 | 636 | Show |
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| 2015-10-06 | Episode #28: Making Python Fast: Profiling Python Code | 50:10 | 214 | Show |
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| 2015-09-29 | Episode #27 Four Years of Python for High Schoolers | 44:35 | 92 | |
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| 2015-09-22 | #26 Deploying Python Web Applications | 55:56 | 753 | |
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| 2015-09-15 | #25 Effective Python | 54:05 | 1,207 | |
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| 2015-09-08 | Episode #24: Fluent Python | 1:08:21 | 3,177 | Show |
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| 2015-09-01 | Episode #23: 3D Printing with Python at Authentise | 46:58 | 181 | Show |
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| 2015-08-25 | Episode #22: CPython Internals and Learning Python with pythontutor.com | 1:02:36 | 430 | Show |
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| 2015-08-24 | Episode #21: PyPy - The JIT Compiled Python Implementation | 53:57 | 256 | Show |
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| 2015-08-24 | #20: Interactive Python and Teaching Python: Beyond Text Books | 48:47 | 306 | |
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| 2015-08-04 | Episode #19: Automate the Boring Stuff with Python | 41:06 | 5,870 | Show |
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| 2015-07-28 | Episode #17: Python on bare metal with MicroPython | 51:31 | 2,908 | Show |
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| 2015-07-28 | Episode #18: Python Anti-patterns and other mistakes | 48:17 | 497 | Show |
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| 2015-07-14 | Episode #16: Python at Netflix | 56:47 | 818 | Show |
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| 2015-07-07 | #15 Python at Spotify, PSF, and PyLadies | 49:01 | 395 | Show |
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| 2015-06-30 | Episode #14: Moving from PHP to Python 3 with Patreon | 49:27 | 740 | Show |
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| 2015-06-23 | #13 Flask web framework and much, much more | 50:02 | 560 | |
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| 2015-06-16 | Episode #12: Deep Dive into Modules and Packages in Python | 52:10 | 2,907 | Show |
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| 2015-06-09 | Episode #11: PyImageSearch and Computer Vision | 50:07 | 1,302 | Show |
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| 2015-06-02 | Episode #10: Bringing Python to the Masses with Hosting and DevOps at PythonAnywhere | 1:05:38 | 87 | Show |
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| 2015-06-02 | Bringing Python to the Masses with Hosting and DevOps at PythonAnywhere | 1:05:38 | 319 | |
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| 2015-05-26 | Docker for the Python Developer | 39:25 | 992 | |
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| 2015-05-21 | Teaching Python at Grok Learning and Classrooms | 37:04 | 1,761 | Show |
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| 2015-05-12 | Episode #7: Robot Operating System (ROS) and ROSPy with Dirk Thomas | 49:50 | 2,549 | Show |
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| 2015-05-05 | Episode #6: Requests, PyCon, and Python's future with Kenneth Rietz | 43:52 | 296 | Show |
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| 2015-04-28 | Episode #5: SQLAlchemy and data access in Python | 1:02:43 | 2,138 | Show |
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| 2015-04-27 | Episode #4: Enterprise Python and Large-Scale Projects | 54:06 | 1,205 | Show |
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| 2015-04-27 | Episode #3: Pyramid Web Framework | 48:11 | 2,983 | Show |
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| 2015-04-27 | Episode #2: Python and MongoDB | 35:00 | 1,783 | Show |
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| 2015-04-27 | Episode #1: EVE - RESTful APIs for humans | 40:44 | 9,341 | Show |
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