| 1. | Afterbirth BEGINNERS GUIDE - Top 10 Beginner Binding of Isaac Tips - Isaac Guide for New Players! | 8,067 | Guide | The Binding of Isaac: Rebirth
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| 2. | Binding of Isaac Afterbirth Item Spotlight - Soy Milk Synergies | 2,207 | | The Binding of Isaac: Rebirth
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| 3. | How to Unlock THE FORGOTTEN in Isaac - Booster Pack 5 NEW CHARACTER! | 2,001 | Guide | The Binding of Isaac: Rebirth
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| 4. | Binding of Isaac FINAL BOOSTER PACK 5 Overview - New Items - What's in The Forgotten Update? | 939 | Vlog | The Binding of Isaac: Rebirth
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| 5. | Afterbirth Plus SECOND BOOSTER PACK New Items - What are the Isaac Booster Pack 2 changes? | 917 | Let's Play | The Binding of Isaac: Rebirth
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| 6. | Isaac FORGOTTEN Tips and Tricks - Top 10 Forgotten Binding of Isaac Tips - Isaac Forgotten Guide! | 858 | Guide | The Binding of Isaac: Rebirth
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| 7. | Best Seeds for Unlocking THE LOST - Binding of Isaac Rebirth - How to Unlock The Lost | 783 | Guide | The Binding of Isaac: Rebirth
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| 8. | Afterbirth Plus March BOOSTER PACK New Items and Trinkets - What are the Isaac Booster Pack changes? | 701 | Let's Play | The Binding of Isaac: Rebirth
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| 9. | Afterbirth Plus March BOOSTER PACK - New Cards and Other Changes in Isaac Booster Pack March! | 360 | Let's Play | The Binding of Isaac: Rebirth
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| 10. | π² Isaac Afterbirth Plus Item Spotlight - The D1 π²- What does the D1 do? How to use the D1! | 305 | Guide | The Binding of Isaac: Rebirth
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| 11. | Antibirth CO-OP Gameplay! ππ« Let's Play Isaac Antibirth Co Op Mode Episode 1 - Isaac COOP w/ Kasey | 276 | Let's Play | The Binding of Isaac: Rebirth
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| 12. | Binding of Isaac Afterbirth Item Spotlight - How to Use Forever Alone | 239 | Guide | The Binding of Isaac: Rebirth
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| 13. | Binding of Isaac Afterbirth Item Spotlight - Magic Mushroom | 213 | | The Binding of Isaac: Rebirth
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| 14. | π Isaac Afterbirth+ Gameplay Part 1! π Let's Play Binding of Isaac AFTERBIRTH+ Episode 1 | 187 | Let's Play | The Binding of Isaac: Rebirth
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| 15. | Afterbirth Plus APRIL FOOL'S Daily Challenge! - April 1st 2017 - April Fool's Daily! | 161 | | The Binding of Isaac: Rebirth
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| 16. | π²π° GREEDIER MODE Gameplay π°π² - Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 2 | 151 | Let's Play | The Binding of Isaac: Rebirth
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| 17. | Isaac Booster Pack Gameplay - Sprinkler Gameplay, Sprinkler Synergies, Buddy in a Box | 150 | | The Binding of Isaac: Rebirth
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| 18. | π Isaac Afterbirth+ Gameplay Part 1! NEW SAVE! π Let's Play Binding of Isaac AFTERBIRTH+ Episode 1 | 142 | Let's Play | The Binding of Isaac: Rebirth
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| 19. | βΈ Isaac Afterbirth Plus Item Spotlight - Pause βΈ - What does Pause do? How to use Pause! | 136 | Guide | The Binding of Isaac: Rebirth
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| 20. | Let's Play Binding of Isaac AFTERBIRTH Daily Challenges - Satoru Iwata Tribute | 123 | Let's Play | The Binding of Isaac: Rebirth
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| 21. | Isaac Antibirth Gameplay Part 1! - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 1 | 110 | Let's Play | The Binding of Isaac: Rebirth
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| 22. | β‘οΈβ± ZIP Achievement in Isaac Afterbirth Plus! β±β‘οΈ How to beat The Lamb in under 20 Minutes! | 90 | Guide | The Binding of Isaac: Rebirth
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| 23. | Binding of Isaac Afterbirth Mod Spotlight - The Binning off Isek Aferberts Mod Gameplay | 84 | | The Binding of Isaac: Rebirth
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| 24. | π Afterbirth+ APOLLYON Gameplay π - SECRET FLOOR! Let's Play AFTERBIRTH PLUS Gameplay - Episode 4 | 63 | Let's Play | The Binding of Isaac: Rebirth
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| 25. | Antibirth CO OP Gameplay! ππ« Let's Play Isaac Antibirth Co Op Mode Episode 2 - Isaac COOP w/ Kasey | 58 | Let's Play | The Binding of Isaac: Rebirth
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| 26. | π Afterbirth+ BACKASSWARDS Challenge! π Let's Play Binding of Isaac AFTERBIRTH PLUS - Episode 6 | 57 | Let's Play | The Binding of Isaac: Rebirth
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| 27. | π IT'S THE KEY Achievement in Isaac Afterbirth Plus! π How to get It's the Key Steam Achievement | 57 | Guide | The Binding of Isaac: Rebirth
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| 28. | Isaac Booster Pack Gameplay - Black Hole Gameplay, Black Hole Synergies, Lil Delirium | 56 | | The Binding of Isaac: Rebirth
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| 29. | Afterbirth Plus EASTER Daily Challenge! - April 16th 2017 - Easter Daily! | 56 | | The Binding of Isaac: Rebirth
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| 30. | Isaac Antibirth Run! - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 2 | 55 | Let's Play | The Binding of Isaac: Rebirth
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| 31. | β ULTRA HARD Challenge! β Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 8 | 53 | Let's Play | The Binding of Isaac: Rebirth
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| 32. | π©π© SCAT MAN Challenge! π©π© - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 4 | 49 | Let's Play | The Binding of Isaac: Rebirth
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| 33. | π»β Afterbirth+ LOST RUN! βπ» Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 3 | 49 | Let's Play | The Binding of Isaac: Rebirth
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| 34. | Binding of Isaac Rebirth - Building a Super Bandage Girl (Part 3 of 3) | 48 | | The Binding of Isaac: Rebirth
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| 35. | π£π Antibirth ANNOUNCER! π£π - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 5 | 43 | Let's Play | The Binding of Isaac: Rebirth
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| 36. | Let's Play Binding of Isaac Rebirth Gameplay - Episode 1 - Lord of the Flies | 42 | Let's Play | The Binding of Isaac: Rebirth
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| 37. | π°β΄ KEEPER DELIRIUM RUN! β΄π° Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 17 | 41 | Let's Play | The Binding of Isaac: Rebirth
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| 38. | Let's Play Binding of Isaac AFTERBIRTH Gameplay - Episode 1 - Isaac | 40 | Let's Play | The Binding of Isaac: Rebirth
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| 39. | ππ Azazel BOSS RUSH?! NEW SAVE! ππ Let's Play AFTERBIRTH PLUS Gameplay - Episode 2 | 39 | Let's Play | The Binding of Isaac: Rebirth
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| 40. | ISAAC DELIRIUM RUN! Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 25 | 38 | Let's Play | The Binding of Isaac: Rebirth
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| 41. | Isaac New Save File! The Binding of Isaac: Afterbirth Plus Episode 1 Let's Play! [Twitch VOD] | 38 | Let's Play | The Binding of Isaac: Rebirth
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| 42. | π§β‘ Cain SPEED RUN?! NEW SAVE! β‘π§ Let's Play AFTERBIRTH PLUS Gameplay - Episode 3 | 38 | Let's Play | The Binding of Isaac: Rebirth
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| 43. | ULTRA HARD Challenge! Let's Play Binding of Isaac AFTERBIRTH PLUS Ultra Hard Challenge - Episode 21 | 38 | Let's Play | The Binding of Isaac: Rebirth
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| 44. | π TROLLED by WORST Antibirth Item π - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 9 | 38 | Let's Play | The Binding of Isaac: Rebirth
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| 45. | Antibirth CO OP Gameplay! ππ« Let's Play Isaac Antibirth Co Op Mode Episode 3 - Isaac COOP w Kasey | 36 | Let's Play | The Binding of Isaac: Rebirth
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| 46. | π§π§ Antibirth BETHANY Gameplay! π§π§ - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 3 | 36 | Let's Play | The Binding of Isaac: Rebirth
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| 47. | π¬β±β‘ JACOB AND ESAU BOSS RUSH! β‘β±π¬ Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 29 | 34 | Let's Play | The Binding of Isaac: Rebirth
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| 48. | Binding of Isaac Rebirth - Building a Super Bandage Girl (Part 1 of 3) | 33 | | The Binding of Isaac: Rebirth
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| 49. | π²π° LILITH GREEDIER MODE! π°π² Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 7 | 33 | Let's Play | The Binding of Isaac: Rebirth
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| 50. | β‘β± AFTERBIRTH PLUS Daily Challenges β±β‘ - January 3rd 2017 Afterbirth+ Daily Run | 32 | | The Binding of Isaac: Rebirth
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| 51. | π² Let's Unlock the D6! π² Let's Play Binding of Isaac AFTERBIRTH PLUS Episode 87 - 2nd Save Part 4 | 32 | Let's Play | The Binding of Isaac: Rebirth
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| 52. | π²π° BLUE BABY GREEDIER MODE! π°π² Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 5 | 32 | Let's Play | The Binding of Isaac: Rebirth
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| 53. | β‘β‘ TURBO Challenge! β‘β‘ - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 6 | 31 | Let's Play | The Binding of Isaac: Rebirth
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| 54. | FIEND FOLIO Mod in The Binding of Isaac! | 31 | | The Binding of Isaac: Rebirth
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| 55. | π€π Denouement ππ€ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 67 | 30 | Let's Play | The Binding of Isaac: Rebirth
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| 56. | π§β ANTIBIRTH ALTERNATE FLOORS! π§β - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 7 | 30 | Let's Play | The Binding of Isaac: Rebirth
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| 57. | Antibirth CO OP Gameplay! ππ« Let's Play Isaac Antibirth Co Op Mode Episode 5 - Isaac COOP w Kasey | 28 | Let's Play | The Binding of Isaac: Rebirth
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| 58. | ππβ‘ April Fool's DAILY RUN! β‘ππ Let's Play AFTERBIRTH PLUS Gameplay - Episode 4 | 28 | Let's Play | The Binding of Isaac: Rebirth
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| 59. | ππ APOLLYON MEGA SATAN Run! ππ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 9 | 28 | Let's Play | The Binding of Isaac: Rebirth
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| 60. | π‘β£ BLOODY MARY Challenge! π‘β£ - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 8 | 28 | Let's Play | The Binding of Isaac: Rebirth
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| 61. | ππ° AZAZEL Greed Mode! π°π Let's Play AFTERBIRTH PLUS Gameplay - Episode 12 | 28 | Let's Play | The Binding of Isaac: Rebirth
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| 62. | πΏβ β° AZAZEL DELIRIUM RUN! β°β πΏ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 19 | 27 | Let's Play | The Binding of Isaac: Rebirth
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| 63. | π»β΄ THE LOST VOID RUN! β΄π» Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 27 | 27 | Let's Play | The Binding of Isaac: Rebirth
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| 64. | SAMSON DELIRIUM RUN! - Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 24 | 27 | Let's Play | The Binding of Isaac: Rebirth
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| 65. | ππ SEEING DOUBLE Challenge ππ - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 12 | 27 | Let's Play | The Binding of Isaac: Rebirth
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| 66. | πͺβ Antibirth SECRETS! βπͺ - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 10 | 27 | Let's Play | The Binding of Isaac: Rebirth
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| 67. | πΏπ°π² AZAZEL GREEDIER MODE! π²π°πΏ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay Episode 18 | 27 | Let's Play | The Binding of Isaac: Rebirth
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| 68. | π΄π± Unlocking BLANK CARD! π±π΄ Let's Play AFTERBIRTH PLUS Gameplay - Episode 93 - 2nd Save Part 10 | 26 | Let's Play | The Binding of Isaac: Rebirth
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| 69. | Kasey's First MEGA SATAN FIGHT?! - Antibirth CO OP Gameplay! ππ« Isaac Co Op Mode Episode 4 | 26 | Let's Play | The Binding of Isaac: Rebirth
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| 70. | πβΆ Afterbirth+ PONG Challenge! πβΆ Let's Play Binding of Isaac AFTERBIRTH PLUS - Episode 22 | 26 | Let's Play | The Binding of Isaac: Rebirth
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| 71. | π»βοΈ WAKA WAKA Challenge! NEW SAVE! βοΈπ» Let's Play AFTERBIRTH PLUS Gameplay - Episode 7 | 26 | Let's Play | The Binding of Isaac: Rebirth
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| 72. | ππ DAD'S HOME Challenge! ππ Let's Play Afterbirth Plus Devil's Harvest Mod Gameplay Episode 11 | 26 | Let's Play | The Binding of Isaac: Rebirth
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| 73. | Let's Play Binding of Isaac AFTERBIRTH Gameplay - Episode 2 - Azazel GREED MODE | 26 | Let's Play | The Binding of Isaac: Rebirth
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| 74. | π‘π Antibirth - RELATIONSHIP RUINER? ππ‘ Let's Play Isaac Antibirth CO OP Mode Episode 6 | 26 | Let's Play | The Binding of Isaac: Rebirth
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| 75. | πΆπ£οΈ Lazy Road Crossers π£οΈπΆββοΈ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 64 | 24 | Let's Play | The Binding of Isaac: Rebirth
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| 76. | π΅β β° BLUE BABY CORPSE RUN! β°β π΅ Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 30 | 24 | Let's Play | The Binding of Isaac: Rebirth
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| 77. | Item Pools Be One RACE with Hutts Gaming! Afterbirth Mods | 24 | | The Binding of Isaac: Rebirth
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| 78. | π‘π‘ ISAAC'S AWAKENING Challenge π‘π‘ - Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 14 | 24 | Let's Play | The Binding of Isaac: Rebirth
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| 79. | ππ APRIL'S FOOL CHALLENGE! ππ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 20 | 24 | Let's Play | The Binding of Isaac: Rebirth
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| 80. | Let's Play Binding of Isaac AFTERBIRTH Gameplay - Episode 3 - Lazarus | 24 | Let's Play | The Binding of Isaac: Rebirth
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| 81. | βͺβ‘ MAUSOLEUM BOSS RUSH! β‘βͺ Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 31 | 23 | Let's Play | The Binding of Isaac: Rebirth
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| 82. | π€ KEEEEEEEEEPERRRRRRRRRR! π€ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 60 | 23 | Let's Play | The Binding of Isaac: Rebirth
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| 83. | π·οΈβοΈ THE HOST Challenge! NEW SAVE! βοΈπ·οΈ Let's Play AFTERBIRTH PLUS Gameplay - Episode 6 | 23 | Let's Play | The Binding of Isaac: Rebirth
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| 84. | AFTERBIRTH PLUS MOD IDEAS Request - Send me your best Afterbirth+ Mod Ideas! | 22 | Tutorial | The Binding of Isaac: Rebirth
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| 85. | Let's Play Binding of Isaac AFTERBIRTH Daily Challenges - December 25th 2015 - Christmas Daily | 22 | Let's Play | The Binding of Isaac: Rebirth
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| 86. | π²π° KEEPER GREEDIER MODE! π°π² Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 14 | 22 | Let's Play | The Binding of Isaac: Rebirth
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| 87. | ππ² Isaac with NO D6! π²π Let's Play AFTERBIRTH PLUS Gameplay - Episode 9 | 22 | Let's Play | The Binding of Isaac: Rebirth
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| 88. | π΅π° BLUE BABY GREEDIER MODE! π°π΅ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 46 | 22 | Let's Play | The Binding of Isaac: Rebirth
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| 89. | ππ€ EVIL GENIUS Challenge! π€π Let's Play Afterbirth Plus Devil's Harvest Mod Gameplay Episode 10 | 22 | Let's Play | The Binding of Isaac: Rebirth
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| 90. | π²π° APOLLYON GREEDIER MODE! π°π² Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 16 | 22 | Let's Play | The Binding of Isaac: Rebirth
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| 91. | DEVIL'S HARVEST MOD SPOTLIGHT! Let's Play Afterbirth Plus Devil's Harvest Mod Gameplay - GOLEM | 22 | Let's Play | The Binding of Isaac: Rebirth
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| 92. | β΄π CAIN DELIRIUM RUN! CAIN VOID πβ΄ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay Episode 11 | 21 | Let's Play | The Binding of Isaac: Rebirth
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| 93. | βοΈπ Blessed πβοΈ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 55 | 21 | Let's Play | The Binding of Isaac: Rebirth
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| 94. | π« BASEMENT WARFARE Challenge! π« Let's Play Afterbirth Plus Devil's Harvest Mod Gameplay Episode 8 | 21 | Let's Play | The Binding of Isaac: Rebirth
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| 95. | π€ The Keeper Run will be Mine! π€ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 55 | 21 | Let's Play | The Binding of Isaac: Rebirth
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| 96. | π¬ππ« The Brothers Get TROLLED! π«ππ¬ Let's Play Binding of Isaac ANTIBIRTH Gameplay - Episode 34 | 21 | Let's Play | The Binding of Isaac: Rebirth
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| 97. | πβ§ JUDAS Run! NEW SAVE! β§π Let's Play AFTERBIRTH PLUS Gameplay - Episode 8 | 21 | Let's Play | The Binding of Isaac: Rebirth
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| 98. | βπͺ Hold the Door πͺβ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 66 | 21 | Let's Play | The Binding of Isaac: Rebirth
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| 99. | π¦β΄ LAZARUS VOID RUN! β΄π¦ Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 54 | 21 | Let's Play | The Binding of Isaac: Rebirth
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| 100. | πβ£ SAMSON GREEDIER MODE! β£π Let's Play Binding of Isaac AFTERBIRTH PLUS Gameplay - Episode 10 | 21 | Let's Play | The Binding of Isaac: Rebirth
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