Top 100 Most Liked The Binding of Isaac Videos by SuperMegaTop 100 » 200 » 300 » 400 » 500Video TitleRatingCategoryGame1.SuperMega Plays BINDING OF ISAAC - EP 1: Why Cockroaches Are Gross6,689Let's PlayThe Binding of Isaac 2.SuperMega Plays BINDING OF ISAAC - EP 6: Starring Ryan’s Mom4,255Let's PlayThe Binding of Isaac 3.SuperMega Plays BINDING OF ISAAC - EP 2: Sad Guitar Lesson4,126Let's PlayThe Binding of Isaac 4.SuperMega Plays BINDING OF ISAAC - EP 3: LeVar Burton Alarm3,924Let's PlayThe Binding of Isaac 5.SuperMega Plays BINDING OF ISAAC - EP 4: Mom Apologies3,827Let's PlayThe Binding of Isaac 6.SuperMega Plays BINDING OF ISAAC - EP 5: Big Words3,292Let's PlayThe Binding of Isaac Top 100 » 200 » 300 » 400 » 500