| 401. | This NEW Character Is Insane... | 5,057 | | The Binding of Isaac: Rebirth
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| 402. | These New CHAMPION Characters Are Ridiculous | 4,987 | | The Binding of Isaac: Rebirth
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| 403. | The CRAZIEST Technology Item Ever | 5,114 | | The Binding of Isaac: Rebirth
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| 404. | How is This Possible?? | 4,878 | | The Binding of Isaac: Rebirth
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| 405. | This is NOT C Section | 4,898 | | The Binding of Isaac: Rebirth
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| 406. | This New Dice Is INSANE | 4,901 | | The Binding of Isaac: Rebirth
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| 407. | I Finally Found The PERFECT Start... | 5,228 | | The Binding of Isaac: Rebirth
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| 408. | This NEW Item Gives You An Isaac Armada: | 5,031 | | The Binding of Isaac: Rebirth
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| 409. | I Found The Most Beautiful Synergy EVER | 5,082 | | The Binding of Isaac: Rebirth
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| 410. | I Got The RAREST Sacred Heart EVER | 4,907 | | The Binding of Isaac: Rebirth
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| 411. | How I Unlocked the Keeper | 4,909 | | The Binding of Isaac: Rebirth
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| 412. | Repentance Mukbang | 4,910 | | The Binding of Isaac: Rebirth
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| 413. | This New Character Has INSANE Synergies | 4,915 | | The Binding of Isaac: Rebirth
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| 414. | This First Floor is PERFECT | 4,917 | | The Binding of Isaac: Rebirth
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| 415. | The New Isaac Update is HUGE (Repentance v.1.9.7) | 5,623 | Vlog | The Binding of Isaac: Rebirth
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| 416. | This New Character Is CRAZY | 4,927 | | The Binding of Isaac: Rebirth
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| 417. | No Hit Tainted Eden Run Be Like: | 4,930 | | The Binding of Isaac: Rebirth
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| 418. | I Committed TAX EVASION in Repentance | 4,933 | | The Binding of Isaac: Rebirth
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| 419. | I Played Isaac with an EYETRACKER. It was cursed. | 5,220 | | The Binding of Isaac: Rebirth
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| 420. | This Destroys EVERY Boss in ONE Frame | 4,939 | | The Binding of Isaac: Rebirth
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| 421. | This New Character Changes EVERYTHING!! | 5,214 | | The Binding of Isaac: Rebirth
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| 422. | Playing As Dogma is Simply Amazing | 5,530 | | The Binding of Isaac: Rebirth
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| 423. | How I Unlocked Birthright | 4,951 | | The Binding of Isaac: Rebirth
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| 424. | This NEW Item Is ABSOLUTELY CRAZY | 5,321 | | The Binding of Isaac: Rebirth
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| 425. | How I Unlocked Sacred Orb | 4,955 | | The Binding of Isaac: Rebirth
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| 426. | This New Character Literally Has INFINITE Luck: | 5,806 | | The Binding of Isaac: Rebirth
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| 427. | I Played the Most PUNISHING Character Ever | 5,267 | | The Binding of Isaac: Rebirth
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| 428. | Perfection, But It's Upgradable | 5,364 | | The Binding of Isaac: Rebirth
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| 429. | I Achieved the Cricket's Head SPEEDRUN World Record | 4,992 | | The Binding of Isaac: Rebirth
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| 430. | This Crane Game Gave Me EVERYTHING | 4,993 | | The Binding of Isaac: Rebirth
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| 431. | They Made Curse Of The Tower 2. It's even worse. | 5,300 | | The Binding of Isaac: Rebirth
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| 432. | LUCKIEST Secret Room Possible | 4,995 | | The Binding of Isaac: Rebirth
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| 433. | The Character That Can Do (Literally) Everything | 5,004 | | The Binding of Isaac: Rebirth
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| 434. | This New Character Is RIDICULOUS | 6,048 | | The Binding of Isaac: Rebirth
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| 435. | They Added NEW Milk. It Gave Me INFINITE Tears. | 5,229 | | The Binding of Isaac: Rebirth
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| 436. | The New Modded Tech Item Is INSANE | 5,293 | | The Binding of Isaac: Rebirth
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| 437. | Literally Every Mattman Run: | 5,009 | | The Binding of Isaac: Rebirth
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| 438. | How I Got R Key in 1.82 Seconds | 5,713 | | The Binding of Isaac: Rebirth
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| 439. | I Found The CRAZIEST Quality 4 Ever. | 5,345 | | The Binding of Isaac: Rebirth
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| 440. | I Found The CRAZIEST First Floor In Isaac... | 5,346 | | The Binding of Isaac: Rebirth
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| 441. | This Floor Gave Me EVERY Quality 4 Item | 5,023 | | The Binding of Isaac: Rebirth
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| 442. | Luckiest Eden Start EVER | 5,025 | | The Binding of Isaac: Rebirth
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| 443. | I've NEVER Made A Bigger Mistake... | 5,030 | | The Binding of Isaac: Rebirth
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| 444. | These New Synergies Are INCREDIBLE | 5,033 | | The Binding of Isaac: Rebirth
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| 445. | This Upgraded Revelation Is INSANE | 5,179 | | The Binding of Isaac: Rebirth
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| 446. | This Modded Character STEALS Enemy HP... | 5,041 | | The Binding of Isaac: Rebirth
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| 447. | The D6 Just Got A CRAZY Upgrade: | 5,594 | | The Binding of Isaac: Rebirth
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| 448. | The Most Satisfying Luck EVER | 5,052 | | The Binding of Isaac: Rebirth
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| 449. | This Item Gives You FREE Quality 4's | 5,055 | | The Binding of Isaac: Rebirth
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| 450. | This New Rune Gave Me INFINITE Stats | 5,312 | | The Binding of Isaac: Rebirth
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| 451. | This NEW Demon Character Evolves!! | 5,269 | | The Binding of Isaac: Rebirth
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| 452. | What INFINITE Luck Looks Like | 5,078 | | The Binding of Isaac: Rebirth
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| 453. | Most Confusing Modded Character | 5,677 | | The Binding of Isaac: Rebirth
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| 454. | I Found The RAREST Room In Isaac | 5,096 | | The Binding of Isaac: Rebirth
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| 455. | THE Best Forgotten Item | 5,100 | | The Binding of Isaac: Rebirth
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| 456. | What Starting With GOLDEN Brimstone Looks Like: | 5,413 | | The Binding of Isaac: Rebirth
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| 457. | Rock Bottom But 1000x Worse | 5,426 | | The Binding of Isaac: Rebirth
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| 458. | Damocles is OP... when you don't get hit | 5,109 | | The Binding of Isaac: Rebirth
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| 459. | This Should LITERALLY Never Happen | 5,112 | | The Binding of Isaac: Rebirth
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| 460. | I Got The BEST Eden Start. It was a mistake. | 5,377 | | The Binding of Isaac: Rebirth
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| 461. | Proof That Dead God Makes You Luckier: | 5,129 | | The Binding of Isaac: Rebirth
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| 462. | The Run Was Rigged From The Start | 5,136 | | The Binding of Isaac: Rebirth
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| 463. | Isaac's NEW Difficulty Is Completely: | 5,831 | | The Binding of Isaac: Rebirth
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| 464. | MEGA SWORD | 5,148 | | The Binding of Isaac: Rebirth
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| 465. | Tainted Forgotten.exe | 5,154 | | The Binding of Isaac: Rebirth
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| 466. | I Found The CRAZIEST Angel Item In Isaac | 5,492 | | The Binding of Isaac: Rebirth
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| 467. | The New Isaac Update Is INSANE (Repentance v1.9.2) | 5,732 | Vlog | The Binding of Isaac: Rebirth
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| 468. | The Most Satisfying Eden Start: | 5,164 | | The Binding of Isaac: Rebirth
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| 469. | The CHEAPEST Free Win I've Ever Seen | 5,167 | | The Binding of Isaac: Rebirth
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| 470. | These NEW Synergies Are INSANELY FUN... | 5,564 | | The Binding of Isaac: Rebirth
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| 471. | This Isaac Challenge Made Me Cry | 5,189 | | The Binding of Isaac: Rebirth
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| 472. | This New Modded Item Is RIDICULOUS | 5,190 | | The Binding of Isaac: Rebirth
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| 473. | Isaac Rigged Moment | 5,193 | | The Binding of Isaac: Rebirth
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| 474. | The Most SATISFYING Start In Isaac History? | 7,115 | | The Binding of Isaac: Rebirth
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| 475. | How ONE Button Press INSTANTLY Broke My Game: | 5,195 | | The Binding of Isaac: Rebirth
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| 476. | This Synergy Is EASILY the Most Satisfying | 5,211 | | The Binding of Isaac: Rebirth
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| 477. | This NEW Character Is Adorable | 5,917 | | The Binding of Isaac: Rebirth
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| 478. | This NEW Shovel Can Dig Up Quality 4's: | 6,126 | | The Binding of Isaac: Rebirth
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| 479. | This NEW Item Gave Me Unlimited Tears | 5,899 | | The Binding of Isaac: Rebirth
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| 480. | I Achieved 1 in 1,000,000 Luck | 6,636 | | The Binding of Isaac: Rebirth
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| 481. | The Character That Has INFINITE Items: | 5,222 | | The Binding of Isaac: Rebirth
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| 482. | World's Smallest Isaac Character | 5,223 | | The Binding of Isaac: Rebirth
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| 483. | Spindown Dice is S-Tier | 5,226 | | The Binding of Isaac: Rebirth
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| 484. | What Infinite Stats ACTUALLY Looks Like: | 5,409 | | The Binding of Isaac: Rebirth
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| 485. | This New Tech Dice Is LITERALLY Cheating | 6,204 | | The Binding of Isaac: Rebirth
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| 486. | This Modded Void Rework Is Absolutely AMAZING | 5,235 | | The Binding of Isaac: Rebirth
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| 487. | How I Unlocked the Forgotten | 5,235 | | The Binding of Isaac: Rebirth
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| 488. | They Added a NEW Angel Fight. It's insane. | 5,683 | | The Binding of Isaac: Rebirth
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| 489. | This NEW Item Is So Satisfying | 5,782 | | The Binding of Isaac: Rebirth
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| 490. | This Character Has The MAXIMUM Damage Multiplier: | 6,021 | | The Binding of Isaac: Rebirth
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| 491. | This New Modded Character Is SO SATISFYING | 5,605 | | The Binding of Isaac: Rebirth
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| 492. | I Gulped EVERY Trinket in Isaac. It was a mistake. | 5,271 | Let's Play | The Binding of Isaac: Rebirth
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| 493. | Playable Siren Is INCREDIBLE | 5,272 | | The Binding of Isaac: Rebirth
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| 494. | Incredibly Satisfying Shot | 5,275 | | The Binding of Isaac: Rebirth
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| 495. | Least Powerful Modded Character | 6,147 | | The Binding of Isaac: Rebirth
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| 496. | This Dice Gives The RAREST Items: | 5,282 | | The Binding of Isaac: Rebirth
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| 497. | The New Death Certificate Is Absolutely INSANE | 5,624 | | The Binding of Isaac: Rebirth
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| 498. | I'll Literally Never Get This Lucky Again | 5,288 | | The Binding of Isaac: Rebirth
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| 499. | Golden Diplopia Is INSANE | 5,290 | | The Binding of Isaac: Rebirth
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| 500. | Isaac Online Is Crazy | 5,731 | | The Binding of Isaac: Rebirth
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