| 301. | Tainted Forgotten.exe | 5,154 | | The Binding of Isaac: Rebirth
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| 302. | MEGA SWORD | 5,148 | | The Binding of Isaac: Rebirth
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| 303. | Isaac's NEW Difficulty Is Completely: | 5,831 | | The Binding of Isaac: Rebirth
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| 304. | The Run Was Rigged From The Start | 5,136 | | The Binding of Isaac: Rebirth
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| 305. | Proof That Dead God Makes You Luckier: | 5,129 | | The Binding of Isaac: Rebirth
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| 306. | I Got The BEST Eden Start. It was a mistake. | 5,377 | | The Binding of Isaac: Rebirth
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| 307. | This Should LITERALLY Never Happen | 5,112 | | The Binding of Isaac: Rebirth
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| 308. | Damocles is OP... when you don't get hit | 5,109 | | The Binding of Isaac: Rebirth
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| 309. | Rock Bottom But 1000x Worse | 5,426 | | The Binding of Isaac: Rebirth
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| 310. | What Starting With GOLDEN Brimstone Looks Like: | 5,413 | | The Binding of Isaac: Rebirth
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| 311. | THE Best Forgotten Item | 5,100 | | The Binding of Isaac: Rebirth
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| 312. | Most Confusing Modded Character | 5,677 | | The Binding of Isaac: Rebirth
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| 313. | I Found The RAREST Room In Isaac | 5,096 | | The Binding of Isaac: Rebirth
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| 314. | What INFINITE Luck Looks Like | 5,078 | | The Binding of Isaac: Rebirth
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| 315. | This NEW Demon Character Evolves!! | 5,269 | | The Binding of Isaac: Rebirth
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| 316. | This New Rune Gave Me INFINITE Stats | 5,312 | | The Binding of Isaac: Rebirth
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| 317. | This Item Gives You FREE Quality 4's | 5,055 | | The Binding of Isaac: Rebirth
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| 318. | The Most Satisfying Luck EVER | 5,052 | | The Binding of Isaac: Rebirth
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| 319. | The D6 Just Got A CRAZY Upgrade: | 5,594 | | The Binding of Isaac: Rebirth
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| 320. | This Modded Character STEALS Enemy HP... | 5,041 | | The Binding of Isaac: Rebirth
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| 321. | This Upgraded Revelation Is INSANE | 5,179 | | The Binding of Isaac: Rebirth
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| 322. | These New Synergies Are INCREDIBLE | 5,033 | | The Binding of Isaac: Rebirth
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| 323. | I've NEVER Made A Bigger Mistake... | 5,030 | | The Binding of Isaac: Rebirth
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| 324. | Luckiest Eden Start EVER | 5,025 | | The Binding of Isaac: Rebirth
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| 325. | This Floor Gave Me EVERY Quality 4 Item | 5,023 | | The Binding of Isaac: Rebirth
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| 326. | I Found The CRAZIEST First Floor In Isaac... | 5,346 | | The Binding of Isaac: Rebirth
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| 327. | I Found The CRAZIEST Quality 4 Ever. | 5,345 | | The Binding of Isaac: Rebirth
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| 328. | How I Got R Key in 1.82 Seconds | 5,713 | | The Binding of Isaac: Rebirth
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| 329. | Literally Every Mattman Run: | 5,009 | | The Binding of Isaac: Rebirth
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| 330. | The New Modded Tech Item Is INSANE | 5,293 | | The Binding of Isaac: Rebirth
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| 331. | They Added NEW Milk. It Gave Me INFINITE Tears. | 5,229 | | The Binding of Isaac: Rebirth
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| 332. | The Character That Can Do (Literally) Everything | 5,004 | | The Binding of Isaac: Rebirth
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| 333. | This New Character Is RIDICULOUS | 6,048 | | The Binding of Isaac: Rebirth
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| 334. | LUCKIEST Secret Room Possible | 4,995 | | The Binding of Isaac: Rebirth
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| 335. | This Crane Game Gave Me EVERYTHING | 4,993 | | The Binding of Isaac: Rebirth
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| 336. | They Made Curse Of The Tower 2. It's even worse. | 5,300 | | The Binding of Isaac: Rebirth
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| 337. | I Achieved the Cricket's Head SPEEDRUN World Record | 4,992 | | The Binding of Isaac: Rebirth
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| 338. | Perfection, But It's Upgradable | 5,364 | | The Binding of Isaac: Rebirth
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| 339. | I Played the Most PUNISHING Character Ever | 5,267 | | The Binding of Isaac: Rebirth
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| 340. | This New Character Literally Has INFINITE Luck: | 5,806 | | The Binding of Isaac: Rebirth
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| 341. | How I Unlocked Sacred Orb | 4,955 | | The Binding of Isaac: Rebirth
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| 342. | This NEW Item Is ABSOLUTELY CRAZY | 5,321 | | The Binding of Isaac: Rebirth
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| 343. | How I Unlocked Birthright | 4,951 | | The Binding of Isaac: Rebirth
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| 344. | Playing As Dogma is Simply Amazing | 5,530 | | The Binding of Isaac: Rebirth
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| 345. | This New Character Changes EVERYTHING!! | 5,214 | | The Binding of Isaac: Rebirth
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| 346. | This Destroys EVERY Boss in ONE Frame | 4,939 | | The Binding of Isaac: Rebirth
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| 347. | I Played Isaac with an EYETRACKER. It was cursed. | 5,220 | | The Binding of Isaac: Rebirth
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| 348. | I Committed TAX EVASION in Repentance | 4,933 | | The Binding of Isaac: Rebirth
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| 349. | No Hit Tainted Eden Run Be Like: | 4,930 | | The Binding of Isaac: Rebirth
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| 350. | This New Character Is CRAZY | 4,927 | | The Binding of Isaac: Rebirth
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| 351. | The New Isaac Update is HUGE (Repentance v.1.9.7) | 5,623 | Vlog | The Binding of Isaac: Rebirth
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| 352. | This First Floor is PERFECT | 4,917 | | The Binding of Isaac: Rebirth
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| 353. | This New Character Has INSANE Synergies | 4,915 | | The Binding of Isaac: Rebirth
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| 354. | Repentance Mukbang | 4,910 | | The Binding of Isaac: Rebirth
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| 355. | How I Unlocked the Keeper | 4,909 | | The Binding of Isaac: Rebirth
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| 356. | I Got The RAREST Sacred Heart EVER | 4,907 | | The Binding of Isaac: Rebirth
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| 357. | I Found The Most Beautiful Synergy EVER | 5,082 | | The Binding of Isaac: Rebirth
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| 358. | This NEW Item Gives You An Isaac Armada: | 5,031 | | The Binding of Isaac: Rebirth
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| 359. | I Finally Found The PERFECT Start... | 5,228 | | The Binding of Isaac: Rebirth
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| 360. | This New Dice Is INSANE | 4,901 | | The Binding of Isaac: Rebirth
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| 361. | This is NOT C Section | 4,898 | | The Binding of Isaac: Rebirth
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| 362. | How is This Possible?? | 4,878 | | The Binding of Isaac: Rebirth
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| 363. | The CRAZIEST Technology Item Ever | 5,114 | | The Binding of Isaac: Rebirth
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| 364. | These New CHAMPION Characters Are Ridiculous | 4,987 | | The Binding of Isaac: Rebirth
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| 365. | This NEW Character Is Insane... | 5,057 | | The Binding of Isaac: Rebirth
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| 366. | This Trick Gets You INFINITE LUCK | 6,137 | | The Binding of Isaac: Rebirth
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| 367. | Isaac, but I take the WORSE Item... | 5,300 | | The Binding of Isaac: Rebirth
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| 368. | Playable Dio Is ACTUALLY Amazing | 6,735 | | The Binding of Isaac: Rebirth
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| 369. | How I Scammed The Shopkeeper | 5,406 | | The Binding of Isaac: Rebirth
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| 370. | This New Character Is INSANELY Challenging... | 5,379 | | The Binding of Isaac: Rebirth
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| 371. | This NEW Sword Item Is Simply Amazing | 5,489 | | The Binding of Isaac: Rebirth
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| 372. | The New Sword Item Is CRAZY | 5,265 | | The Binding of Isaac: Rebirth
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| 373. | How I Got MAGIC MUSHROOM in 1.52 Seconds | 5,256 | | The Binding of Isaac: Rebirth
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| 374. | NEVER Make This Mistake | 4,815 | | The Binding of Isaac: Rebirth
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| 375. | This Destroys EVERY Boss in ONE Frame | 4,813 | | The Binding of Isaac: Rebirth
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| 376. | The Dice That MULTIPLIES Items | 5,235 | | The Binding of Isaac: Rebirth
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| 377. | The Jacob and Esau Experience | 4,794 | | The Binding of Isaac: Rebirth
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| 378. | Playable Ultra Greed Is AMAZING... | 5,220 | | The Binding of Isaac: Rebirth
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| 379. | This NEW Sacred Orb Is Amazing | 4,791 | | The Binding of Isaac: Rebirth
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| 380. | Craziest First Floor | 5,732 | | The Binding of Isaac: Rebirth
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| 381. | How I Broke My Game with ONE Bomb: | 4,772 | | The Binding of Isaac: Rebirth
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| 382. | The New Modded Azazel Has The THICKEST Brimstone... | 5,021 | | The Binding of Isaac: Rebirth
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| 383. | This NEW Item Was My Biggest Mistake | 4,992 | | The Binding of Isaac: Rebirth
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| 384. | This NEW Godhead Is Insane | 5,024 | | The Binding of Isaac: Rebirth
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| 385. | This NEW Glitched Crown Dice Is Actually Satisfying | 5,123 | | The Binding of Isaac: Rebirth
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| 386. | The Luckiest I've EVER Been | 4,760 | | The Binding of Isaac: Rebirth
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| 387. | The Most DEVIOUS Character Ever | 5,090 | | The Binding of Isaac: Rebirth
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| 388. | This Synergy Makes You Literally INVINCIBLE | 5,229 | | The Binding of Isaac: Rebirth
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| 389. | Most Cursed Character EVER | 4,856 | | The Binding of Isaac: Rebirth
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| 390. | They Made Mongo Baby A Character. He's INSANE | 5,338 | | The Binding of Isaac: Rebirth
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| 391. | This new character is INSANE... | 5,161 | | The Binding of Isaac: Rebirth
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| 392. | 100% Risk, 0% Reward | 4,743 | | The Binding of Isaac: Rebirth
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| 393. | It's Not Over. | 4,733 | | The Binding of Isaac: Rebirth
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| 394. | I Found The NEW Brimstone. It's Crazy. | 5,465 | | The Binding of Isaac: Rebirth
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| 395. | Least Lucky Mattman Run: | 6,157 | | The Binding of Isaac: Rebirth
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| 396. | How Am I Alive?? | 4,721 | | The Binding of Isaac: Rebirth
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| 397. | The Day I Got ONLY Quality 4 Items | 4,715 | | The Binding of Isaac: Rebirth
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| 398. | The Time I Got EVERY Quality 4 Item: | 4,709 | | The Binding of Isaac: Rebirth
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| 399. | I've Never Had THIS Luck | 4,709 | | The Binding of Isaac: Rebirth
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| 400. | How I Unlocked Tainted Eden | 4,709 | | The Binding of Isaac: Rebirth
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