| 301. | The Binding of Isaac [230][No Commentary] - Unbreakable Bones | 55:18 | | The Binding of Isaac: Rebirth
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| 302. | The Binding of Isaac [222][No Commentary] - Honestly Chaotic | 55:03 | | The Binding of Isaac: Rebirth
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| 303. | The Binding of Isaac [76][No Commentary] - Adrenaline Rush | 54:57 | | The Binding of Isaac: Rebirth
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| 304. | The Binding of Isaac [361][No Commentary] - Eternal Ghost | 54:49 | | The Binding of Isaac: Rebirth
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| 305. | The Binding of Isaac [56][No Commentary] - Icy Blade | 54:44 | | The Binding of Isaac: Rebirth
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| 306. | The Binding of Isaac [172][No Commentary] - Reverse Run | 54:36 | | The Binding of Isaac: Rebirth
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| 307. | The Binding of Isaac [136][No Commentary] - Cursed! | 54:35 | | The Binding of Isaac: Rebirth
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| 308. | The Binding of Isaac [479][No Commentary] - Almost Untouchable Apollyon | 54:28 | | The Binding of Isaac: Rebirth
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| 309. | The Binding of Isaac [158][No Commentary] - Starting Low | 54:21 | | The Binding of Isaac: Rebirth
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| 310. | The Binding of Isaac [255][No Commentary] - Smithecac | 54:16 | | The Binding of Isaac: Rebirth
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| 311. | The Binding of Isaac [364][No Commentary] - Keeper NEO | 53:59 | | The Binding of Isaac: Rebirth
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| 312. | The Binding of Isaac [133][No Commentary] - Ruined Demon | 53:51 | | The Binding of Isaac: Rebirth
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| 313. | The Binding of Isaac [19][No Commentary] - Homing Tears | 53:38 | | The Binding of Isaac: Rebirth
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| 314. | The Binding of Isaac [77][No Commentary] - Unknown | 53:14 | | The Binding of Isaac: Rebirth
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| 315. | The Binding of Isaac [163][No Commentary] - Rainbow Chaos | 52:53 | | The Binding of Isaac: Rebirth
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| 316. | The Binding of Isaac [24][No Commentary] - Getting Blue | 52:48 | | The Binding of Isaac: Rebirth
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| 317. | The Binding of Isaac [151][No Commentary] - Void to Void | 52:45 | | The Binding of Isaac: Rebirth
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| 318. | The Binding of Isaac [224][No Commentary] - Blue VS Big Blue | 52:43 | | The Binding of Isaac: Rebirth
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| 319. | The Binding of Isaac [303][No Commentary] - An Explosive Run | 52:38 | | The Binding of Isaac: Rebirth
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| 320. | The Binding of Isaac [69][No Commentary] - Shocking | 52:36 | | The Binding of Isaac: Rebirth
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| 321. | The Binding of Isaac [421][No Commentary] - Bone Rush | 52:21 | | The Binding of Isaac: Rebirth
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| 322. | The Binding of Isaac [292][No Commentary] - Forgotten Isaac | 52:18 | | The Binding of Isaac: Rebirth
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| 323. | The Binding of Isaac [204][No Commentary] - The Lost Run | 52:10 | | The Binding of Isaac: Rebirth
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| 324. | The Binding of Isaac [16][No Commentary] - Ghost Boy | 52:01 | | The Binding of Isaac: Rebirth
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| 325. | The Binding of Isaac [80][No Commentary] - Lots of Friends | 51:51 | | The Binding of Isaac: Rebirth
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| 326. | The Binding of Isaac [100][No Commentary] - Mirrored Stupidity | 51:48 | | The Binding of Isaac: Rebirth
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| 327. | The Binding of Isaac [191][No Commentary] - Nailed It | 51:42 | | The Binding of Isaac: Rebirth
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| 328. | The Binding of Isaac [251][No Commentary] - Jacob's Heart | 51:41 | | The Binding of Isaac: Rebirth
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| 329. | The Binding of Isaac [43][No Commentary] - What's the worst that could happen? | 51:28 | | The Binding of Isaac: Rebirth
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| 330. | The Binding of Isaac [156][No Commentary] - BOOM | 51:25 | | The Binding of Isaac: Rebirth
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| 331. | The Binding of Isaac [159][No Commentary] - Guardian Angel | 51:08 | | The Binding of Isaac: Rebirth
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| 332. | The Binding of Isaac [387][Twitch VOD] - Soffriamo ancora con Tainted Keeper | 51:02 | | The Binding of Isaac: Rebirth
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| 333. | The Binding of Isaac [261][No Commentary] - Ghost Lamb | 50:54 | | The Binding of Isaac: Rebirth
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| 334. | The Binding of Isaac [218][No Commentary] - Holy Demon | 50:51 | | The Binding of Isaac: Rebirth
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| 335. | The Binding of Isaac [239][No Commentary] - Greedierlene | 50:34 | | The Binding of Isaac: Rebirth
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| 336. | The Binding of Isaac [369][No Commentary] - Lost Sight | 50:34 | | The Binding of Isaac: Rebirth
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| 337. | The Binding of Isaac [190][No Commentary] - Multi Eyenail Eden | 50:32 | | The Binding of Isaac: Rebirth
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| 338. | The Binding of Isaac [200][No Commentary] - Blessed Cain | 50:22 | | The Binding of Isaac: Rebirth
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| 339. | The Binding of Isaac [141][No Commentary] - Family Man | 50:22 | | The Binding of Isaac: Rebirth
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| 340. | The Binding of Isaac [320][No Commentary] - Umbical Lilith | 50:19 | | The Binding of Isaac: Rebirth
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| 341. | The Binding of Isaac [37][No Commentary] - Dying and dying and dying and... | 50:15 | | The Binding of Isaac: Rebirth
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| 342. | The Binding of Isaac [102][No Commentary] - Suicide King | 49:51 | | The Binding of Isaac: Rebirth
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| 343. | The Binding of Isaac [106][No Commentary] - Bomb Man | 49:30 | | The Binding of Isaac: Rebirth
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| 344. | The Binding of Isaac [213][No Commentary] - A Step Back | 49:22 | | The Binding of Isaac: Rebirth
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| 345. | The Binding of Isaac [481][No Commentary] - Money Rage | 49:14 | | The Binding of Isaac: Rebirth
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| 346. | The Binding of Isaac [350][No Commentary] - Poor Ghost Attempts | 49:12 | | The Binding of Isaac: Rebirth
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| 347. | The Binding of Isaac [461][No Commentary] - Curiosity killed the cat | 49:07 | | The Binding of Isaac: Rebirth
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| 348. | The Binding of Isaac [210][No Commentary] - GREEDIER! | 48:59 | | The Binding of Isaac: Rebirth
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| 349. | The Binding of Isaac [155][No Commentary] - THE POOP | 48:57 | | The Binding of Isaac: Rebirth
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| 350. | The Binding of Isaac [394][Twitch VOD] - Last Floor Depression | 48:49 | | The Binding of Isaac: Rebirth
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| 351. | The Binding of Isaac [70][No Commentary] - Tiny Knights | 48:48 | | The Binding of Isaac: Rebirth
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| 352. | The Binding of Isaac [214][No Commentary] - Demon Attempt | 48:46 | | The Binding of Isaac: Rebirth
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| 353. | The Binding of Isaac [232][No Commentary] - Water Man | 48:42 | | The Binding of Isaac: Rebirth
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| 354. | The Binding of Isaac [223][No Commentary] - Pandora's Room | 48:32 | | The Binding of Isaac: Rebirth
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| 355. | The Binding of Isaac [22][No Commentary] - Back To Mom's Heart | 48:26 | | The Binding of Isaac: Rebirth
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| 356. | The Binding of Isaac [05][No Commentary] - Getting a Bonus Chance | 48:24 | | The Binding of Isaac: Rebirth
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| 357. | The Binding of Isaac [193][No Commentary] - SuperIperMegaUltraDeadlyLaserDrop | 48:23 | | The Binding of Isaac: Rebirth
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| 358. | The Binding of Isaac [339][No Commentary] - Delete This | 47:47 | | The Binding of Isaac: Rebirth
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| 359. | The Binding of Isaac [83][No Commentary] - Deadly Bombs | 47:45 | | The Binding of Isaac: Rebirth
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| 360. | The Binding of Isaac [82][No Commentary] - Victory Loop | 47:16 | | The Binding of Isaac: Rebirth
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| 361. | The Binding of Isaac [488][No Commentary] - 2nd to last greed | 47:05 | | The Binding of Isaac: Rebirth
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| 362. | The Binding of Isaac [162][No Commentary] - Aprils Fool | 47:05 | | The Binding of Isaac: Rebirth
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| 363. | The Binding of Isaac [118][No Commentary] - Speedrunning is Hard | 46:52 | | The Binding of Isaac: Rebirth
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| 364. | The Binding of Isaac [120][No Commentary] - Changing Topic | 46:46 | | The Binding of Isaac: Rebirth
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| 365. | The Binding of Isaac [72][No Commentary] - Wasted Potential | 46:44 | | The Binding of Isaac: Rebirth
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| 366. | The Binding of Isaac [61][No Commentary] - Static Tears | 46:29 | | The Binding of Isaac: Rebirth
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| 367. | The Binding of Isaac [14][No Commentary] - Sharp Baby Isaac | 46:28 | | The Binding of Isaac: Rebirth
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| 368. | The Binding of Isaac [334][No Commentary] - Never the Same | 45:59 | | The Binding of Isaac: Rebirth
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| 369. | The Binding of Isaac [282][No Commentary] - Bad Keeper | 45:54 | | The Binding of Isaac: Rebirth
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| 370. | The Binding of Isaac [462][No Commentary] - Blue Destruciton | 45:27 | | The Binding of Isaac: Rebirth
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| 371. | The Binding of Isaac [105][No Commentary] - Another Demon Run | 45:12 | | The Binding of Isaac: Rebirth
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| 372. | The Binding of Isaac [11][No Commentary] - Taste the Rainbow | 45:07 | | The Binding of Isaac: Rebirth
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| 373. | The Binding of Isaac [26][No Commentary] - Almost There | 44:58 | | The Binding of Isaac: Rebirth
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| 374. | The Binding of Isaac [379][No Commentary] - Greedier Keeper | 44:48 | | The Binding of Isaac: Rebirth
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| 375. | The Binding of Isaac [480][No Commentary] - Holy Demon | 44:47 | | The Binding of Isaac: Rebirth
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| 376. | The Binding of Isaac [58][No Commentary] - Unsee | 44:28 | | The Binding of Isaac: Rebirth
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| 377. | The Binding of Isaac [227][No Commentary] - JudHush | 44:13 | | The Binding of Isaac: Rebirth
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| 378. | The Binding of Isaac [111][No Commentary] - The Nameless Run | 44:12 | | The Binding of Isaac: Rebirth
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| 379. | The Binding of Isaac [466][No Commentary] - Skeleday | 44:08 | | The Binding of Isaac: Rebirth
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| 380. | The Binding of Isaac [128][No Commentary] - The Void | 43:58 | | The Binding of Isaac: Rebirth
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| 381. | The Binding of Isaac [140][No Commentary] - Purist | 43:36 | | The Binding of Isaac: Rebirth
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| 382. | The Binding of Isaac [20][No Commentary] - Bad Roll | 43:22 | | The Binding of Isaac: Rebirth
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| 383. | The Binding of Isaac [36][No Commentary] - Burning | 43:21 | | The Binding of Isaac: Rebirth
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| 384. | The Binding of Isaac [273][No Commentary] - MisseD20 Chance | 43:18 | | The Binding of Isaac: Rebirth
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| 385. | The Binding of Isaac [206][No Commentary] - Life Bandages | 43:18 | | The Binding of Isaac: Rebirth
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| 386. | The Binding of Isaac [139][No Commentary] - It's in the Tarots | 42:52 | | The Binding of Isaac: Rebirth
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| 387. | The Binding of Isaac [211][No Commentary] - Demon RHush | 42:50 | | The Binding of Isaac: Rebirth
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| 388. | The Binding of Isaac [198][No Commentary] - Random Selection | 42:32 | | The Binding of Isaac: Rebirth
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| 389. | The Binding of Isaac [208][No Commentary] - Explosive Lazarus | 41:35 | | The Binding of Isaac: Rebirth
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| 390. | The Binding of Isaac [199][No Commentary] - Rocket Magda | 41:30 | | The Binding of Isaac: Rebirth
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| 391. | The Binding of Isaac [59][No Commentary] - Learning More | 41:14 | | The Binding of Isaac: Rebirth
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| 392. | The Binding of Isaac [407][No Commentary] - Fun Rerun | 41:02 | | The Binding of Isaac: Rebirth
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| 393. | The Binding of Isaac [368][No Commentary] - Forget It | 40:52 | | The Binding of Isaac: Rebirth
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| 394. | The Binding of Isaac [29][No Commentary] - Not Scary Enough | 40:35 | | The Binding of Isaac: Rebirth
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| 395. | The Binding of Isaac [165][No Commentary] - Embrace Chaos | 40:27 | | The Binding of Isaac: Rebirth
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| 396. | The Binding of Isaac [15][No Commentary] - Laser Field Sight | 40:10 | | The Binding of Isaac: Rebirth
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| 397. | The Binding of Isaac [85][No Commentary] - Greedy | 40:01 | | The Binding of Isaac: Rebirth
|
| 398. | The Binding of Isaac [201][No Commentary] - Greedy Sam | 39:31 | | The Binding of Isaac: Rebirth
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| 399. | The Binding of Isaac [459][No Commentary] - Mega Samson | 39:14 | | The Binding of Isaac: Rebirth
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| 400. | The Binding of Isaac [10][No Commentary] - Double Beam of Death | 39:09 | | The Binding of Isaac: Rebirth
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