Top 100 The Binding of Isaac: Rebirth Videos With The Most Comments by ScrabblePlaysTop 100 » 200 » 300 » 400 » 500Video TitleCommentsCategoryGame1.Binding of Isaac - What a horrible night to have a curse (Nintendo Switch)7Let's PlayThe Binding of Isaac: Rebirth 2.Binding of Isaac: Afterbirth Plus (Nintendo Switch) - Lil Brimstone4Let's PlayThe Binding of Isaac: Rebirth Top 100 » 200 » 300 » 400 » 500