| 1. |  Markiplier | STOP CHASING ME!! | Alien Isolation - Part 4 | 4,087,146 | Let's Play |
| 2. | Markiplier | TOO MANY FEELS ;_; | Alien Isolation - Part 10 | 3,122,631 | Let's Play |
| 3. | Bumbles | Avocado is a Fruit - Jacksepticeye & Markiplier Animated in Help Desk 2 | 1,561,493 | Let's Play |
| 4. | loltyler1 VODS | Tyler1 Plays Alien: Isolation | 1,081,147 | Let's Play |
| 5. | Maximilian Dood | This Is TERRIFYING - MAX PLAYS: Alien Isolation - Hard Mode 1st Full Playthru (Part 1) | 571,295 | Let's Play |
| 6. | TFS Gaming | Krillin Plays: Alien Isolation - 1 - | 444,457 | Let's Play |
| 7. | Maximilian Dood | I LOVE THIS GAME & I'm Exhausted: MAX PLAYS Alien Isolation - Hard Mode 1st Full Playthru (FINALE) | 286,995 | Let's Play |
| 8. | Maximilian Dood | This Alien IS HUNTING ME: MAX PLAYS Alien Isolation - Hard Mode 1st Full Playthru (Part 2) | 283,708 | Let's Play |
| 9. | TFS Gaming | Krillin Plays: Alien Isolation - 2 - | 251,425 | Let's Play |
| 10. | Rooster Teeth | News: PS4 Passes 4.2 Million + 13 New Steam Machines + Alien: Isolation Announced | Rooster Teeth | 237,523 | Let's Play |
| 11. | TFS Gaming | Krillin Plays; Alien Isolation - 3 - | 185,206 | Let's Play |
| 12. | TFS Gaming | Krillin Plays: Alien Isolation - 4 - | 166,613 | Let's Play |
| 13. | TFS Gaming | Krillin Plays: Alien Isolation - 5 - | 157,365 | Let's Play |
| 14. | IGN | Alien: Isolation - How to Survive an Unpredictable Alien | 155,502 | Let's Play |
| 15. | TFS Gaming | Krillin Plays: Alien Isolation - 6 - | 141,697 | Let's Play |
| 16. | TFS Gaming | Krillin Plays: Alien Isolation - 7 - | 141,078 | Let's Play |
| 17. | James Willems | They Took Our Jobs! Let's Play Alien Isolation Part 1 | 135,830 | Let's Play |
| 18. | Prince Vegeta | I Am Sexy! - Vegeta Plays Alien Isolation Part 1 | 128,763 | Let's Play |
| 19. | TFS Gaming | Krillin Plays: Alien Isolation - 8 - | 111,006 | Let's Play |
| 20. | TFS Gaming | Krillin Plays: Alien Isolation - 10 - | 105,641 | Let's Play |
| 21. | TFS Gaming | Krillin Plays: Alien Isolation - 9 - | 102,673 | Let's Play |
| 22. | TFS Gaming | Krillin Plays: Alien Isolation - 12 - | 101,017 | Let's Play |
| 23. | Daily Dose of xQc | xQc Plays Alien: Isolation with Chat | Part 1 | 100,852 | Let's Play |
| 24. | TFS Gaming | Krillin Plays: Alien Isolation - 11 - | 100,213 | Let's Play |
| 25. | Maximilian Dood | MAX PLAYS: ALIEN ISOLATION - Crew Expendable & Last Survivor DLC | 97,970 | Let's Play |
| 26. | xChaseMoney2 | Alien Isolation Gameplay Part 1 - Y'all Wrong For This One | 95,691 | Let's Play |
| 27. | x5 CiNEMA | Alien: Isolation -The 'Reel' Movie (Game Movie) | 92,692 | Let's Play |
| 28. | TFS Gaming | Krillin Plays: Alien Isolation - 14 - | 92,578 | Let's Play |
| 29. | TFS Gaming | Krillin Plays: Alien Isolation - 41 - FINALE | 91,135 | Let's Play |
| 30. | ProJared Plays! | JERKS with Guns | Alien: Isolation #1 | ProJared Plays | 90,545 | Let's Play |
| 31. | TFS Gaming | Krillin Plays: Alien Isolation - 13 - | 89,464 | Let's Play |
| 32. | TFS Gaming | Krillin Plays: Alien Isolation - 21 - | 88,831 | Let's Play |
| 33. | TFS Gaming | Krillin Plays: Alien Isolation - 20 - | 87,682 | Let's Play |
| 34. | Ephemeral Rift | ASMR Let's Play Alien Isolation #1 ( PC ) | 87,463 | Let's Play |
| 35. | TFS Gaming | Krillin Plays: Alien Isolation - 15 - | 87,300 | Let's Play |
| 36. | TFS Gaming | Krillin Plays: Alien Isolation - 22 - | 84,468 | Let's Play |
| 37. | TFS Gaming | Krillin Plays: Alien Isolation - 19 - | 84,421 | Let's Play |
| 38. | TFS Gaming | Krillin Plays: Alien Isolation - 16 - | 84,311 | Let's Play |
| 39. | TFS Gaming | Krillin Plays: Alien Isolation - 18 - | 83,744 | Let's Play |
| 40. | TFS Gaming | Krillin Plays: Alien Isolation - 17 - | 81,937 | Let's Play |
| 41. | TFS Gaming | Krillin Plays: Alien Isolation - 23 - | 81,221 | Let's Play |
| 42. | lonniedos | OFFICE CHAIR ZOMBIE ATTACK (iPhone Gameplay Video) | 80,592 | Let's Play |
| 43. | TFS Gaming | Krillin Plays: Alien Isolation - 24 - | 73,042 | Let's Play |
| 44. | TFS Gaming | Krillin Plays: Alien Isolation - 29 - | 72,871 | Let's Play |
| 45. | TFS Gaming | Krillin Plays: Alien Isolation - 25 - | 72,549 | Let's Play |
| 46. | TFS Gaming | Krillin Plays: Alien Isolation - 34 - | 72,281 | Let's Play |
| 47. | Avoiding The Puddle | Aris Unflushes Alien: Isolation - Full Playthrough (Part 1) | 72,110 | Let's Play |
| 48. | TFS Gaming | Krillin Plays: Alien Isolation - 26 - | 71,646 | Let's Play |
| 49. | TFS Gaming | Krillin Plays: Alien Isolation - 30 - | 70,263 | Let's Play |
| 50. | TFS Gaming | Krillin Plays: Alien Isolation - 31 - | 69,831 | Let's Play |
| 51. | TFS Gaming | Krillin Plays: Alien Isolation - 27 - | 68,748 | Let's Play |
| 52. | TFS Gaming | Krillin Plays: Alien Isolation - 32 - | 67,537 | Let's Play |
| 53. | TFS Gaming | Krillin Plays: Alien Isolation - 28 - | 66,503 | Let's Play |
| 54. | TFS Gaming | Krillin Plays: Alien Isolation - 35 - | 66,112 | Let's Play |
| 55. | ProJared Plays! | HE'S HERE | Alien: Isolation #2 | ProJared Plays | 65,907 | Let's Play |
| 56. | TFS Gaming | Krillin Plays: Alien Isolation - 33 - | 63,718 | Let's Play |
| 57. | TFS Gaming | Krillin Plays: Alien Isolation - 37 - | 59,412 | Let's Play |
| 58. | TFS Gaming | Krillin Plays: Alien Isolation - 38 - | 56,995 | Let's Play |
| 59. | TFS Gaming | Krillin Plays: Alien Isolation - 39 - | 56,444 | Let's Play |
| 60. | TFS Gaming | Krillin Plays: Alien Isolation - 40 - | 56,225 | Let's Play |
| 61. | PlayStation | PlayStation E3 2014 | Alien: Isolation | Live Coverage (PS4) | 55,073 | Let's Play |
| 62. | TFS Gaming | Krillin Plays: Alien Isolation - 36 - | 54,199 | Let's Play |
| 63. | ProJared Plays! | HIDE & SEEK CHAMPION | Alien: Isolation #4 | ProJared Plays | 50,326 | Let's Play |
| 64. | Chicago Reacts | "I'M NOT FREAKING OUT" - Alien: Isolation (part 1) by SovietWomble | First Time Reaction | 49,465 | Let's Play |
| 65. | ProJared Plays! | DICK Robots! | Alien: Isolation #3 | ProJared Plays | 49,259 | Let's Play |
| 66. | James Willems | Big Dumb Aliens - Let's Play Alien Isolation Pt 3 | 48,139 | Let's Play |
| 67. | Ephemeral Rift | ASMR Let's Play Alien Isolation #6 | 46,076 | Let's Play |
| 68. | TFS Gaming | Krillin Plays: SOMA - 15 - Data Not Found | 45,216 | Let's Play |
| 69. | BeatEmUps | 10 GREAT Upcoming Playstation 4 (PSVR) Games For PS4 | 43,534 | Let's Play |
| 70. | Ephemeral Rift | ASMR Let's Play Alien Isolation #3 ( PC ) | 42,689 | Let's Play |
| 71. | ProJared Plays! | NUISANCE! | Alien Isolation #5 | ProJared Plays | 42,472 | Let's Play |
| 72. | ProJared Plays! | EVERYTHING'S ON FIRE | Alien Isolation #6 | ProJared Plays | 42,411 | Let's Play |
| 73. | ProJared Plays! | I am a Big Dumb Idiot | Alien Isolation FINALE | ProJared Plays | 42,272 | Let's Play |
| 74. | Ephemeral Rift | ASMR Let's Play Alien Isolation #5 (PC) | 41,996 | Let's Play |
| 75. | TFS Gaming | Krillin Plays: SOMA - 20 - ROBOT ZOMBIES FROM HELL! | 41,254 | Let's Play |
| 76. | DSPGaming | Alien: Isolation (PS4) playthrough pt1 - Going Streaking | 40,928 | Let's Play |
| 77. | Ephemeral Rift | ASMR Let's Play Alien Isolation #2 ( PC ) | 39,920 | Let's Play |
| 78. | Centerstrain01 | Let's Play: Alien Isolation - PC Max Settings (4K) Hard - Part 1 - Mission #1 & 2 | CenterStrain01 | 38,219 | Let's Play |
| 79. | zachbealetv | HELP ME... PLEASE | ALIEN ISOLATION #1 | 37,721 | Let's Play |
| 80. | Annoying Orange Gaming | Gaming Grape Plays - Alien Isolation: SURVIVAL MODE! | 37,529 | Let's Play |
| 81. | Ephemeral Rift | ASMR Let's Play Alien Isolation #4 ( PC ) | 33,560 | Let's Play |
| 82. | GaLm | [1] Sevastopol Survival (Let's Play/Livestream Alien: Isolation PC w/ GaLm) | 33,471 | Let's Play |
| 83. | ProJared Plays! | MOST EXCITING RACE OF ALL TIME | Alien Isolation #7 | ProJared Plays | 33,088 | Let's Play |
| 84. | Shoto's Twitch VODs | 【6/1/2022】Sick Shoto plays Horror Games with you【Shoto | Alien: Isolation #4】 | 32,676 | Let's Play |
| 85. | ProJared Plays! | More Fire! | Alien Isolation #8 | ProJared Plays | 30,741 | Let's Play |
| 86. | BereghostGames | Alien Isolation Gameplay Walkthrough Playthrough Part 2 Restoring the Power (PC) | 29,163 | Let's Play |
| 87. | Force Gaming | Force Feed - Alien Isolation, PlayStation Now, 14 Steam Machines | 29,064 | Let's Play |
| 88. | NukemDukem | Alien Isolation Walkthrough Part 1 Press Review Let's Play playthrough 1080p HD | 26,704 | Let's Play |
| 89. | Annoying Orange Gaming | Gaming Grape Plays - Alien Isolation #2: Survival Mode ALIEN SNOT! | 26,462 | Let's Play |
| 90. | CohhCarnage | CohhCarnage Plays Alien: Isolation - Episode 1 | 25,922 | Let's Play |
| 91. | ƒ r u 7 7 y | Alien: Isolation 👽 Xbox One X AI Gameplay | 24,470 | Let's Play |
| 92. | BereghostGames | Alien Isolation Gameplay Walkthrough Playthrough Part 1 - The Mission Begins (PC) | 23,349 | Let's Play |
| 93. | MFPallytime | Alien: Isolation | Let's Play #1 | 21,636 | Let's Play |
| 94. | DansGaming | Let's Play ALIEN Isolation - Part 1 - Horror Gameplay | 21,244 | Let's Play |
| 95. | LobosJr | Lobos Plays Alien: Isolation w/ Oculus Rift (Part 1) | 19,894 | Let's Play |
| 96. | Alienware | AlphaPlays - Alien: Isolation Episode 17 | 19,653 | Let's Play |
| 97. | DSPGaming | Alien: Isolation (PS4) playthrough pt2 - Worst Pantry Ever/Cassette Decks IN SPACE | 19,252 | Let's Play |
| 98. | fyrTV | ALIEN ISOLATION - Let's Play - Gizmo | 18,638 | Let's Play |
| 99. | DSPGaming | Alien: Isolation (PS4) playthrough pt3 - Desperate Rescue Mission | 18,595 | Let's Play |
| 100. | Avoiding The Puddle | Aris Unflushes Alien: Isolation - Full Playthrough (Part 3, Final) | 18,177 | Let's Play |
