| 1. |  Nintendo Unity | What Happens When You Have The Highest IQ Possible in Nintendo Games? | 87,671 | |
| 2. | Jerma Stream Archive | Jerma Streams - Big Brain Academy: Brain vs. Brain | 64,681 | |
| 3. | Nintendo of America | Test Your 5-Second Focus with Big Brain Academy: Brain vs. Brain | 56,900 | |
| 4. | IGN | Big Brain Academy: Brain vs. Brain - Official Announcement Trailer | 37,804 | |
| 5. | Nintendo of America | Match the Picture to the Shadow! - Big Brain Academy: Brain vs. Brain - Nintendo Switch | 21,959 | Preview |
| 6. | Nintendo of America | Where are the Birds? - Big Brain Academy: Brain vs. Brain - Nintendo Switch | 19,272 | Preview |
| 7. | Nintendo of America | Pop From Lowest to Highest! – Big Brain Academy: Brain vs. Brain – Nintendo Switch | 16,568 | Preview |
| 8. | AlsoAqua | How Big is Aqua's Brain??? | 16,141 | |
| 9. | Boubon Clipper Ch. | Gura has challenged Past Ina【HoloEN】 | 13,628 | |
| 10. | GameSpot Trailers | Neil Patrick Harris & Family - Big Brain Academy: Brain vs. Brain - Nintendo Switch | 13,068 | |
| 11. | StephenVOD | Big Brain Academy: Brain vs. Brain | VOD 12.17.21 | 12,517 | |
| 12. | xQc Gaming | xQc tries to prove he is smart | Big Brain Academy | 10,477 | |
| 13. | The Kelly Clarkson Show | 4 Amazing Gifts That Will Slay For Kids & Teens | 5,545 | |
| 14. | Sykkuno VODs – Unofficial | [2021/12/05] uh um hmm (Big Brain Academy, Fortnite, VALORANT, Escape Room - The Sick Colleague) | 4,794 | |
| 15. | optantic | Big Brain Academy: Brain vs. Brain Nintendo Switch gameplay | 4,376 | |
| 16. | Speedman | Best of Shu Yamino Big Brain Academy | 4,337 | |
| 17. | Random Tako | Did you know that Smol Ina can make cute noises?【Hololive EN】 | 3,756 | |
| 18. | LongplayArchive | Longplay of Big Brain Academy: Brain vs. Brain | 3,331 | |
| 19. | POPnGAMES | Big Brain Academy Brain Vs. Brain (Nintendo Switch) Unboxing | 3,301 | |
| 20. | GameSpot Trailers | Big Brain Academy: Brain vs. Brain - Overview Trailer - Nintendo Switch | 3,229 | |
| 21. | Sykkuno VODs – Unofficial | [2021/12/04] back to chill days (Big Brain Academy, Century: Age of Ashes, League of Legends) | 3,007 | |
| 22. | Speedman | Best of Enna Alouette Big Brain Academy | 2,915 | |
| 23. | Vidiocy | BIG BRAIN ACADEMY: BRAIN VS. BRAIN 4-Players | Vidiocy | 2,508 | |
| 24. | Dan Ryckert | Big Brain Academy: Brain vs. Brain - Dan Checks Out | 2,178 | |
| 25. | SweetnlowGames | Big Brain Academy is BACK ON NINTENDO SWITCH!! | 2,091 | |
| 26. | GameSpot Trailers | 10 Minutes Of Big Brain Academy: Brain vs. Brain Gameplay | 1,944 | |
| 27. | Mr. Vacca | Big Brain Academy: Brain vs. Brain - Parent vs. Child Challenge! | 1,859 | |
| 28. | Lynley's World | Big Brain Academy: Brain Vs. Brain - Nintendo Switch #Shorts | 1,755 | |
| 29. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Compute) Tick-Tock Turn (15 of 20) | 1,480 | |
| 30. | Luis Alamilla | Big Brain Academy Brain vs Brain Review (Nintendo Switch) | 1,307 | Review |
| 31. | clips the lass | WE'RE GETTING SMART TODAY (Big Brain Academy) [04-13-2025] | 1,119 | |
| 32. | Sodapoppin Archives | Big Brain Academy: Brain vs. Brain - (sodapoppin) - December 5, 2021 | 1,021 | |
| 33. | Sunburned Albino | Largest Brain in North America | 1,004 | |
| 34. | gogamego | Big Brain Academy: Brain vs. Brain for Nintendo Switch! | 997 | |
| 35. | Speedman | Best of Aia Amare Big Brain Academy | 897 | |
| 36. | Speedman | Best of Aster Arcadia Big Brain Academy | 886 | |
| 37. | Millennium | [NEW] Big Brain Academy: Brain vs Brain Nintendo Switch Gameplay episode 2 | 884 | |
| 38. | Sunburned Albino | Drunk Brain Academy Was a Bad Idea | 844 | |
| 39. | AwktheAngel | Big Brain Academy: Brain Vs. Brain - Memorize Category | 800 | |
| 40. | optantic | Big Brain Academy: Brain vs. Brain : How to quickly unlock all Outfits | 797 | |
| 41. | Vxmpire_Blox | Big Brain Academy: Brain vs. Brain Nintendo Switch - Who is smarter? #NintendoSwitch | 764 | |
| 42. | Best Game Videos | Big Brain Academy Brain vs Brain Demo - Nintendo Switch | 744 | |
| 43. | Speedman | Best of Finana Ryugu Big Brain Academy | 730 | |
| 44. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Memorize) Covered Cages (8 of 20) | 682 | |
| 45. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Analyze) Heavyweight (10 of 20) | 681 | |
| 46. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Compute) Mallet Math (14 of 20) | 676 | |
| 47. | MarPar | More Big Brain Academy Brain vs. Brain on Super Elite Difficulty!! - The Co Op Couch | 661 | |
| 48. | Sunburned Albino | Still the Largest Brain in North America | 642 | |
| 49. | Gamer Linear | The Escape Room Chronicles ep2:The Old School Building Gameplay Nintendo Switch | 607 | |
| 50. | StartPlayX | Big Brain Academy Brain VS Brain All Gold Stars Switch | 567 | |
| 51. | AwktheAngel | Big Brain Academy: Brain Vs. Brain - Compute Category | 544 | |
| 52. | Reecee | What Big Brain Academy: Brain vs. Brain Means For Dead Nintendo Franchises | Reecee News | 528 | |
| 53. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Compute) Balloon Burst (16 of 20) | 518 | |
| 54. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Memorize) Reverse Retention (7 of 20) | 508 | |
| 55. | AwktheAngel | Big Brain Academy: Brain Vs. Brain - Analyze Category | 500 | |
| 56. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Compute) Add Agency (13 of 20) | 461 | |
| 57. | AwktheAngel | Big Brain Academy: Brain Vs. Brain - Visualize Category | 458 | |
| 58. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Analyze) Cubegame (9 of 20) | 448 | |
| 59. | Vidiocy | FROM BEGINNER TO ELITE | Big Brain Academy: Brain Vs. Brain 4-Player #2 | Vidiocy | 437 | |
| 60. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Analyze) Speed Sorting (12 of 20) | 425 | |
| 61. | Nintendo Addict | Big Brain Academy: Brain VS Brain | Solo Nintendo Switch Gameplay Live Stream | 403 | |
| 62. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Identify) Whack Match (1 of 20) | 400 | |
| 63. | Vidiocy | FROM SPROUT TO SUPER ELITE | Big Brain Academy: Brain vs. Brain #4 | Vidiocy | 390 | |
| 64. | Ms,Bigglesworth | Nintendo Switch - 2021 - Big Brain Academy -Brain VS Brain - Gameplay - No Commentary | 387 | |
| 65. | AwktheAngel | Big Brain Academy: Brain Vs. Brain - Ghost Clash | 385 | |
| 66. | AwktheAngel | Big Brain Academy: Brain Vs. Brain - Identify Category | 383 | |
| 67. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Compute) Balloon Burst (Free Demo) | 374 | |
| 68. | Mr. Vacca | Big Brain Academy: Brain Vs Brain - 5th Graders Challenge Their Teacher! | 370 | |
| 69. | Speedman | Best of Millie Parfait Big Brain Academy | 370 | |
| 70. | Too Sleepy | Sleepy plays Big Brain Academy: Brain vs. Brain 12/11/2021 | 357 | |
| 71. | Sodapoppin Archives | Big Brain Academy: Brain vs. Brain - (sodapoppin) - December 7, 2021 | 317 | |
| 72. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Analyze) Match Blast (11 of 20) | 317 | |
| 73. | gogamego | Today's Switch Game is Big Brain Academy Brain vs. Brain. #Nintendo | 317 | |
| 74. | Millennium | Big Brain Academy Unboxing Nintendo Switch | 316 | Review |
| 75. | Reecee | Big Brain Academy: Brain vs. Brain (Nintendo Switch) First Impressions | 309 | |
| 76. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Visualize) Get in Shape (buttons) (17 of 20) | 306 | |
| 77. | Nintendo Dads | Big Brain Academy: Brain vs. Brain DEMO - Let's Play | Nintendo Switch | 305 | Let's Play |
| 78. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Identify) Species Spotlight (2 of 20) | 304 | |
| 79. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Memorize) Flash Memory (buttons) (5 of 20) | 292 | |
| 80. | LightForGod | (Switch) Big Brain Academy- Brain vs. Brain Demo Gameplay | 292 | |
| 81. | AwktheAngel | Big Brain Academy: Brain Vs. Brain - Test | 277 | |
| 82. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Identify) Fast Focus (4 of 20) | 270 | |
| 83. | Paul Gale Network | Neil Patrick Harris, Christina Aguilera, & Brie Larson - Nintendo Switch Promos/Discussion with PGN | 265 | |
| 84. | Mr. Vacca | Big Brain Academy: Brain vs Brain Sign Ups for Parent vs. Child and Teacher vs. Student! | 263 | |
| 85. | Millennium | BIG BRAIN ACADEMY Nintendo Switch Gameplay | 254 | Review |
| 86. | Reecee | This is Big Brain Time | Big Brain Academy: Brain vs. Brain (Nintendo Switch) #1 | 241 | |
| 87. | ohfivethirty | Big Brain Academy: Brain vs. Brain | All Unlockable Outfits and More! | 237 | |
| 88. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Memorize) Memo-Random (6 of 20) | 220 | |
| 89. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Identify) Whack Match (Free Demo) | 211 | |
| 90. | BFF Gamer TV | Should we buy Big Brain Academy: Brain vs Brain? | 210 | |
| 91. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Identify) Frame Filler (3 of 20) | 210 | |
| 92. | Marsen Network | This ONE Mode Makes This Game Worth It - Big Brain Academy: Brain Vs Brain | 206 | |
| 93. | Speedman | Shu Yamino Dr. Lobe Voice Montage (Big Brain Academy) | 190 | |
| 94. | Manakyn | Can a Ph.D. Pass Kindergarten? | Let's Play Big Brain Academy: Brain vs. Brain | Gaming Stream | 188 | Let's Play |
| 95. | Lexi Berry | PROVING COLLEGE GIBES U BIG BRAIN™ | 169 | |
| 96. | Paul Gale Network | Big Brain Academy: Brain vs. Brain Trailer, PS5 PlayStation Showcase is Coming, Famitsu for Week 35 | 144 | Let's Play |
| 97. | 宜子骑士 | 和队友比拼“脑力”结果智商被碾压了|(完整字幕已更新)【灵活脑学校 - 一起伸展大脑】(NS) | 142 | |
| 98. | Family Friendly Gaming | Big Brain Academy Brain vs Brain Gameplay | 137 | |
| 99. | Donut Toys and Games | Big Brain Academy: Brain vs. Brain (Visualize) Shadow Shift (Free Demo) | 126 | |
| 100. | Vidiocy | BRAIN TEST | Big Brain Academy: Brain vs. Brain | Vidiocy | 126 | |
