| 1. |  EnterElysium | 893,802 | Big Pharma Marketing and Malpractice #09 - Let's Play | 22:58 |
| 2. | Steejo | 136,851 | Let's Play Big Pharma Part 53 - FINAL | 21:03 |
| 3. | HypnotoadProductions | 122,279 | BIG PHARMA #023 - Ultraviolet Mishap ★ Let's Play Big Pharma [HD][1080p 60FPS] | 19:04 |
| 4. |  Rahmschnitzel | Let's Play | 94,056 | Big Pharma [#36] - Alle geheilt, dann kann ich ja gehen [FINALE] - Let's Play | 20:32 |
| 5. |  Yippee Ki Yay Mr Falcon | 47,782 | Let's Play Big Pharma - Master Dick Rank - End [Big Pharma Gameplay] | 17:46 |
| 6. |  MaxPalaro | 36,866 | Jogando Big Pharma com Max #2 | 26:50 |
| 7. | Stuff+ | 34,013 | Beverage + Big Pharma: Marketing and Malpractice | 35:41 |
| 8. |  TinyPirate | 16,627 | BEST WORST - ep 4 - Let's Play Big Pharma Marketing & Malpractice Gameplay | 35:52 |
| 9. | Ctop | 15,780 | Big Pharma Gameplay - #03 - Damn Catalysts! | 14:52 |
| 10. | tom.io | 13,595 | Big Pharma - Marketing & Malpractice DLC - #5 - Kurz-Let´s Play | 26:19 |
| 11. |  Twisted - HoneyBunnyGames | 6,783 | Let's Play Big Pharma Gameplay - Part 9 - Placebo | 19:58 |
| 12. |  SergiuHellDragoonHQ | 5,354 | Let's Play Big Pharma Part 2 | 19:18 |
| 13. | Pinstar | 4,185 | Big Pharma Marketing & Malpractice 3: Sales Synergy | 25:14 |
| 14. | Modee | 3,378 | Big Pharma Ep 6 | Bankrolled (Big Pharma Gameplay) | 30:05 |
| 15. | Frithgar | 3,368 | Let's Play Big Pharma #2 Curing Tuberculosis! | 34:00 |
| 16. | Mal | 3,156 | Big Pharma - Let's Try Part 15 [Beta Gameplay] Series End | 22:47 |
| 17. | TimmexTV | 3,029 | Big Pharma 34 Keep calm and carry on - [ Deutsch | German | Gameplay | Let's Play ] | 20:06 |
| 18. | Xterminator | 2,930 | Big Pharma EP 8 - Mission 3 Begins! | 26:28 |
| 19. | NLBladeNL | 2,174 | Let's Play Big Pharma - #6: Anal Leakage?? | 23:42 |
| 20. | Fengferth | 2,171 | Big Pharma (M&M Expansion) - 04 Trials & Boosters | 47:12 |
| 21. |  TheGreenLing | 1,921 | Lets Play Big Pharma 6 - Complicated Combinations | 28:58 |
| 22. | Biffa Plays Indie Games | 1,734 | Big Pharma NEW LP on BIFFA PLAYS NOW | 2:28 |
| 23. |  Ellitopia Gaming | 1,697 | Show Me The Money (FINALE) | Big Pharma M&M - Theme Hospital Edition | 38:16 |
| 24. | Nevis LP | 1,601 | Let's Play: Big Pharma - 12 - Mission Gewonnen! [ENDE][HD/Deutsch/German] | 29:34 |
| 25. | Dad's Gaming Addiction | 1,542 | DGA Plays: Big Pharma: Marketing and Malpractice (Ep 1. Gameplay / Let's Play) | 37:48 |
| 26. | Cybie1111 | 1,513 | Let's Play Big Pharma: Marketing and Malpractice Blind Part 18: Alzheimer's a Bitch Finale | 29:37 |
| 27. | Rodcombarro | 1,224 | Big Pharma Marketing and Malpractice #06 Analizador y Mejoras GAMEPLAY ESPAÑOL | 10:44 |
| 28. | SentinalhMC | 1,134 | Big Pharma - Let's Play #5 - Mega Debt | 30:51 |
| 29. |  Sushix | 1,101 | BIG PHARMA: MARKETING AND MALPRACTICE - Drug Empire! - Gameplay | 28:26 |
| 30. | TheNoobsKanal | 882 | Alpträume sind kein Problem - Big Pharma #17 [German Deutsch Lets Play] | 31:01 |
| 31. |  BelannaerTV | 865 | Big Pharma - Marketing & Malpractice DLC - Part 3 | 33:38 |
| 32. | IceTone Gaming | 844 | Big Pharma Marketing & Malpractice - 06: Show me the money (Master) | 2:42:42 |
| 33. | Arthenex Games | 794 | Let's Play Big Pharma: Episode 15 | 1:05:00 |
| 34. | Code Cod | 780 | Big Pharma Gameplay Español creamos nuevas medicinas avanzadas tutorial español | 36:27 |
| 35. | iVisionGames | 514 | Big Pharma - #03 - Show Me The Money - Lets Play | 22:28 |
| 36. | Raccooninja | 452 | Big Pharma #6 - Sales Crisis or Brilliant Plan?!? (Marketing and Malpractice) | 38:14 |
| 37. | Spielkinder | 452 | Big Pharma #4 - Let's Play mit Pillen | 22:04 |
| 38. | Honki Tonk | 442 | Lets Play Big Pharma (Blind) 89 | 26:02 |
| 39. | yodayun | 440 | Let's Play: Big Pharma : Part 15 : Patents in your face! | 26:28 |
| 40. | Lirico | 434 | [ESTRENO] BIG PHARMA | DLC MARKETING & MALPRACTICE | ESPAÑOL | 27:01 |
| 41. | Merric Gaming | 412 | Let's Play – Big Pharma - Episode 3 [Fund Those Missions!]: | 40:56 |
| 42. | André Lampe | 353 | Let's Play Big Pharma - "Faktorio mit Pillen" [13] bei den Gewinnen verguckt | 32:36 |
| 43. | JoshFTL | 347 | Farts Help you Sleep - Big Pharma Beta Tutorial and Preview | 21:19 |
| 44. | Raffmonster | 228 | Let's Play "Big Pharma" - Teil 3 'Entdecker auf Überstunden' (German/Deutsch) | 17:29 |
| 45. | Keywii Plays | 221 | Keywii Plays Big Pharma (44) | 22:31 |
| 46. |  R.E.A. | 196 | Let's Play Big Pharma ! - Ep 6 : Rubiks cube | 23:06 |
| 47. |  Pru | 181 | Big Pharma Erkundung und Forschung / Angezockt Lets Play Gameplay Deutsch | 18:18 |
| 48. | will309productions | 172 | Lets Look At Big Pharma Eps.8 | 6:14 |
| 49. | E'Pock Plays | 167 | Big Pharma EP-12 Let's Play | 52:00 |
| 50. | Nerdyversal Studios | 144 | LetsPlay Big Pharma #2 Katalysatoren | 26:04 |
| 51. | Smithy1294 | 124 | Big Pharma #8 | Let's Play Big Pharma | 1:15:59 |
| 52. | DarkRa | 74 | Big Pharma Let's Play Lost My Appetite Ep 7 | 27:51 |
| 53. | MadGod | 73 | Madgod Plays - Big Pharma - Part 5 | 32:28 |
| 54. | Las Scottas | 70 | Big Pharma Let's Play 3 - OTC King | 38:25 |
| 55. | CS Gaming Channel | 66 | Lets play big pharma! || Master of Medicine! || Part 5 | 37:01 |
| 56. | VynxarTV | 51 | Let's play Big Pharma - Regular "match" against a competitor | 1:17:07 |
| 57. | Jiggly Blunt | 47 | Big Pharma Marketing and Malpractice [2] | Lets Play | Expanding the Factory | 16:23 |
| 58. | EldestSon | 44 | EldestSon Plays | Big Parma | Three Is The Magic Number | 1:11:32 |
| 59. | SrockJohnny | 29 | Big Pharma #003 [Let's Play] [German] | 23:29 |
| 60. | Gebwell Gaming | 27 | Big Pharma - The Poop Pill! (RLP) | 25:45 |
| 61. | Marcel Baron | 12 | Let's Play Big Pharma #004 - Special - Finale | 1:10:11 |
| 62. | Dolgy | 8 | Let's Play A Bit Of Big Pharma | Episode 2 | 33:40 |
| 63. | Maleficious | 6 | Talking About Malpractice - Big Pharma Part 9 | 15:41 |
| 64. | Eryk Dragonheart | 4 | Let's Play | Big Pharma | Making Weird Pills Part #2 | 21:13 |
| 65. | blohod | 3 | blohod plays Big Pharma #1 | 17:26 |
| 66. |  GamersLV | 3 | Игра Big Pharma выйдет на Xbox One, PlayStation 4 и Nintendo Switch! | 1:37 |
