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| 2. | NintendoComplete | Clue (SNES) Playthrough - NintendoComplete | 58,580 | Let's Play |
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| 4. | AqualungGameReviews | Clue SNES Review | 16,135 | Review |
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| 6. | linkeffect82 | Let's Play Clue (Sega Genesis) #1 1p part1 | 10,397 | Let's Play |
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| 9. | trouble982 | Let's Play Sega Genesis (2) Clue Part 1 | 4,810 | Let's Play |
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| 11. | trouble982 | Let's Play Sega Genesis (2) Clue Part 2 | 3,398 | Let's Play |
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| 13. | WebNations | TAS Clue SNES in 0:26 by Deign | 3,190 | |
| 14. | aetithjnsw | SNES Clue (USA) in 00:26.50 by Deign | 3,101 | |
| 15. | hernandez23 | Clue Title Screen (Sega Genesis) | 2,879 | |
| 16. | nintendonerdsvideos | Clue (SNES) Ending | 2,520 | |
| 17. | SEGA MD2 | Clue (Sega Genesis) - Longplay | 2,412 | |
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| 19. | Cpt. RetroBlue Plays | Playing CLUE for Sega Genesis (4 Player CPU controlled) | 2,141 | |
| 20. | VideoGaming4U | Clue (Super Nintendo) - Long Play | 1,823 | |
| 21. | Alu | Let's Play Clue SNES Pt.2 | 1,452 | |
| 22. | The No Swear Gamer | CLUE SNES Complete Game Longplay Hardest Detective Difficulty Gameplay Only | 1,380 | |
| 23. | Brett Jacquard | Clue for the SNES | 1,198 | |
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| 26. | Derek Fischer (Hiddeninplainview) | Clue on SNES (All Possible Ending Scenes) | 1,083 | |
| 27. | magmawk | RAT - Clue (SNES) or am I just Clueless? Part 2 | 664 | |
| 28. | Steve Klebrowski | Clue SNES gameplay | 663 | |
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| 31. | Legendary Tactics | CLUE Boardgame / How To Learn To Be A REAL DETECTIVE In 9 Easy Lessons | 462 | |
| 32. | Prehistoric Films | Let's Play Clue (SNES) Sleuth | 449 | |
| 33. | AqualungGameReviews | Clue SNES Gameplay (Throwback Thursday - Episode 134) | 435 | Show |
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| 36. | Steve Klebrowski | Clue Sega Genesis gameplay | 423 | |
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| 39. | ももかん -Momokan Vtuber- | 【ももかん視点】犯人を捜せ!6人で推理ボードゲーム「CLUEDO」【#VTUBER】【#ももかんライブ】 | 400 | |
| 40. | Skybilz | Two Intense Games of Clue (SNES) - Twitch Channel Points Redemption | 364 | |
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| 42. | Morgan Kell | Clue (SNES) - BGM 02: Colonel Mustard | 318 | |
| 43. | Vizzed Gameplay Videos | Clue (Sega Genesis) Single party HD - Vizzed.com Play | 306 | |
| 44. | Eric Corp Incorporated | Clue (Genesis / Mega Drive) Playthrough | 294 | Let's Play |
| 45. | spikevegeta | SNESMania Game 065: Clue | 293 | |
| 46. | Zombieslayr3788 | CLUE SEGA GENESIS FULL PLAY THROUGH | 292 | |
| 47. | Glenn O'Brien | Clue (Sega Genesis) | 270 | |
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| 50. | Derek Fischer (Hiddeninplainview) | Every Time I Died: Clue on SNES (Mr. Boddy's POV Edition) | 210 | |
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| 65. | PlayingVideoGames88[PVG88] | Clue (SNES) - Playthrough [Col.Mustard|Detective] | 120 | Let's Play |
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| 96. | 眠ったレトロゲームを掘り起こす ヒロットヨンとまきたんのゲーム実況チャンネル | 【証拠を辿れ!】Clue(SEGAGENESIS)#1 | 54 | |
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