| 1. |  OfficialNerdCubed | 124,808 | Nerd³ Plays... Comix Zone - The Page Master | 21:18 |
| 2. | whoisthisgit | 122,582 | Creepy Bad Endings # 20 | 10:13 |
| 3. | Slope's Game Room (Video Game Documentaries) | 93,073 | Comix Zone: The Complete History - SGR | 12:18 |
| 4. | fusionhub86 | 56,887 | Sega Tunes: Comix Zone, Track 6: Last To Follow | 2:46 |
| 5. | Top Hat Gaming Man | 45,291 | The MAD Story of COMIX ZONE - Why is it so Important!? – SEGA GAMING HISTORY | 19:40 |
| 6. | Kim Justice | 29,657 | Chakan Review - Sega Genesis - Kimble Justice | 8:55 |
| 7. | TheLegendofRenegade | 15,935 | Comix Zone - Episode 3: Page 2-1 (Sega Genesis Remix) | 7:01 |
| 8. | EscapeRouteBritish | 7,379 | ERb :: Comix Zone Achievement Trick | 0:51 |
| 9. | Tyrannicon | 6,202 | RETRO RAGE: Comix Zone (Genesis/Megadrive) | 14:06 |
| 10. | AL82 Retrogaming Longplays | 5,562 | Comix Zone Longplay (Mega Drive/Genesis) [50 FPS] | 42:44 |
| 11. | All Throws | 3,605 | Comix Zone (SEGA Genesis) Fighting Moves Demonstration - All Combos, Throws, Special Moves & Items | 1:51 |
| 12. | Zeusdaz - The Unemulated Retro Game Channel | 1,893 | COMIX ZONE (MEGADRIVE / PS3 - FULL GAME - BAD ENDING) | 44:37 |
| 13. | Just Jamie | 1,686 | Mega Drive CD MSU/MD+ Super Enhanced Games [Time Stamps] #megadrive #megadrivegames #segamegadrive | 0:00 |
| 14. | MoreSauce | 1,464 | Nah, I Just Raged Over Comix Zone Of All Things... | 0:15 |
| 15. | BIGGMILKY | 1,440 | The Chaos Engine - Greatest Video Game Soundtracks | 0:30 |
| 16. | David William Beck (Wartorious) | 1,333 | Comix Zone (Megadrive) | 0:58 |
| 17. | Scatigno | 1,057 | Comix Zone - PSN - Commentary | 7:58 |
| 18. | GamebustersUK | 955 | Comix Zone Part 6 Final | 9:37 |
| 19. | The Legion | 900 | WE ARE SQUISHY CAVEMEN! JOE & MAC GAMEPLAY (Sega Genesis) - DROP THE BOSS | 28:43 |
| 20. | mariotaz | 880 | Comix Zone Playthrough Finale | 9:19 |
| 21. | SuperNerds UK | 840 | Comix Zone on the Sega Megadrive | 0:00 |
| 22. | Genesis VII | 810 | MEGA DRIVE Monday | Comix Zone | Mark VII | 10:46 |
| 23. | Classic From The Attic | 757 | Streets of rage trilogy. #retrogaming #sega #retro #16bit #streetsofrage #custom #megadrive | 0:15 |
| 24. | Abraxas Arcadia | 757 | SEGA Mega Drive / Genesis Classics Challenge - Epic Comeback (Comix Zone) | 1:53 |
| 25. | Sega Head | 732 | Comix Zone - Sega Head | 4:05 |
| 26. | Chris Clarke | 712 | Comix Zone Cheat Sega Megadrive | 0:55 |
| 27. | The Retro Hour (Retro Gaming Podcast) | 688 | 457: Comix Zone: Creating a Mega Drive Cult Classic - The Retro Hour EP457 | 0:00 |
| 28. | VGM Hall of Fame | 666 | VGM Hall Of Fame: Comix Zone - Options | 2:54 |
| 29. | HellfireComms | 661 | The HFC SEGAthon: A Marathon for the AGES! [#14: Comix Zone] | 58:41 |
| 30. | Webster | 647 | Comix Zone - Afr0Blu3's Retro View Episode 08 | 7:40 |
| 31. | TheBigDaddyDReviews1 | 622 | Comix Zone | The Big Daddy D's Classic Game Reviews | 2:28 |
| 32. | andyukmonkey | 573 | Comix Zone - Song 1 - Episode 1-1 music - Megadrive (Real hardware) | 3:14 |
| 33. | Retro Cheating :D | 563 | Retro Cheating :D #AndrettiRacing #SegaSaturn #Sega #Saturn #Gaming #Retro #Gamer #CheatCodes #Sub | 1:00 |
| 34. | Kerr9000 | 552 | Comix Zone Games Room Megadrive/Genesis Review | 7:48 |
| 35. | SPD64 | 538 | 𓆩✦𓆪SEGA'S UNDERRATED GEM𓆩✦𓆪 | Comix Zone | 0:00 |
| 36. | Bare Buddies | 535 | Comix Zone - #9 - "She's dead" - Bare Buddy | 11:43 |
| 37. | PLAION UK | 514 | 5 Things You Need to Know About THE400Mini #the400mini #atari #retrogaming | 0:35 |
| 38. | Know Your Games | 474 | Comix Zone: Episode 3 - Curse of the Dead Ships | 26:13 |
| 39. | Jesse Borondy | 410 | Comix Zone Teaser #drums #drumcover #drummer #comixzone #segagenesis #segamegadrive #teaser #metal | 0:30 |
| 40. | Retro Game Recluse | 402 | Comix Zone (1995) Sega Megadrive Genesis ending [Retro Gaming] | 0:00 |
| 41. | davpreec | 398 | Streets Of Rage Remake - Comix Zone - Playthrough | 0:00 |
| 42. | Funstock | 377 | Comix Zone (Mega Drive/Genesis) Gameplay on a Retron 5 in 720p HD | 4:22 |
| 43. | Pyro Desire | 356 | Playing the games I loved growing up. Part 13. #sega #segagenesis #retrogaming #classicgaming | 0:00 |
| 44. | PompeyGamesRoom | 356 | Pickups: New console & Game Cube, Switch, Megadrive, Saturn, Xbox 360 & PS3 additions | 59:59 |
| 45. | SEGA PIT | 345 | SEGA Critic: S1: Ep 23 - Comix Zone | 9:24 |
| 46. | Mr Products | 343 | Comix Zone Retro Review | 4:53 |
| 47. | Scott Tumilty | 316 | Comix Zone - Woe is the World (Cover) | 2:50 |
| 48. | Tytan Gaming | 313 | Lets Play Comix Zone (MegaDrive) #3 The Good And The Bad | 19:27 |
| 49. | Paul Eales | 306 | ビシバシスペシャル2. [PlayStation - Konami]. (1999). Full Play. | 20:54 |
| 50. | SEGADriven.com | 293 | The Forgotten Comix Zone PC Port | 3:59 |
| 51. | Spawn300 | 265 | Mega Drive κουβέντα - Comix Zone Longplay attempt 1 - Halo TV Series Review | 1:59:16 |
| 52. | Major Playerz | 251 | Playing Comix Zone with Greezy | 1:34:55 |
| 53. | UK Gaming Network | 230 | 19 Racquet Sports games on Amiga RANKED | Retro Game Superleagues | 18:36 |
| 54. | ScouseMouse | 214 | MORTUS COMES TO LIFE - Comix Zone | Part 1 | 15:37 |
| 55. | StevieROM | 213 | The Best Video Games Based on Movies and TV Shows (Part 1 - Ten Games) | 6:14 |
| 56. | lame gag | 205 | Comix Zone - SEGA Mega Drive / Analogue Mega SG Playthrough | 35:20 |
| 57. | RUSHIAN RICHARD | 194 | SEGA Comix Zone ‐ European Megadrive vs US Beta version | A Comparison of the Intro + Episode 1 | 16:22 |
| 58. | 128KB | 173 | Are These The Better JoyCon? | 0:35 |
| 59. | Alpha Chrome Yayo | 169 | Alpha Chrome Yayo - Comix Zone - Into The Zone [Cover] | 3:04 |
| 60. | AlacrityBlue♪ | 164 | Psycrow! - Earthworm Jim (Sega Genesis OST) | 0:58 |
| 61. | Classic Retro Game Room | 152 | Lets Play Comix Zone For The Sega Megadrive Ultimate Collection Classic Retro Game Room | 10:44 |
| 62. | Njenkin | 147 | Comix Zone - SEGA Genesis / Mega Drive - with Commentary !! | 11:46 |
| 63. | John Gage | 128 | Comix Zone Review for the SEGA Mega Drive by John Gage | 11:15 |
| 64. | Deliverance84 | 100 | Night of the Mutants (COMIX ZONE) -EPISODE 1- Page 1-1 & Page 2-1 (Feed My Disease) 2025 D84 REMIX | 0:00 |
| 65. | Retro Output | 93 | Comix Zone (SEGA Megadrive) EP06 Retro Plymouth Gamers Chat + Play | 28:50 |
| 66. | Mysterious0Bob | 87 | Fake World Tournament: MightyKombat vs Admiral | 10:07 |
| 67. | Lucas Green | 84 | LEGO DC Super Villains Custom Builds - Sketch Turner (Comix Zone) | 8:14 |
| 68. | Tomb of Ash | 83 | Let's Play Comix Zone [NO Commentaries] | 19:42 |
| 69. | Iroquois Gaming | 78 | An Underrated 90's Comic Book Classic #retrogaming #retro #gaming #shortvideos #ps5 #pc #xbox | 0:00 |
| 70. | SKIP-RAT GAMING | 76 | COMIX ZONE GAMEPLAY PLAYSTATION 4 CLASSICS SEGA MEGADRIVE COLLECTION | 14:46 |
| 71. | Time Extension | 73 | Comix Zone (Sega Mega Drive / Genesis) Gameplay | 5:51 |
| 72. | Fat Nicks Retro Games Archive | 72 | Comix Zone (Megadrive) | 20:43 |
| 73. | Spirit Wolf Gaming | 63 | Comix Zone (Sega Genesis) | 0:00 |
| 74. | EarphonePretzel | 61 | Frustrating Nostalgia | 20:05 |
| 75. | Kev Gaming XP | 60 | Guess The Classic Game S1 Ep2 | 0:49 |
| 76. | Gamesmaster Uploader | 60 | Bad Influence! S04E02 13/09/95 | 19:56 |
| 77. | MinusInferno | 59 | Comix Zone | Retrospective | 7:14 |
| 78. | AutumnHaunted | 58 | Comix Zone (w/ Bikdip) - A Byte-Size Try - S2 E4 | 38:21 |
| 79. | Thrift Bytes | 54 | Comix Zome - Completing it after 25 years - Twitch Highlights | 8:11 |
| 80. | paulisthebest3uk | 54 | 16th September 2020 Megadrive game Comix Zone | 4:45 |
| 81. | BGShadow Games | 52 | Comix Zone - Arcade Retro Era No7 | #Shorts #Retro | 0:53 |
| 82. | Arcade Attack Retro Gaming Network | 51 | Comix Zone Intro (SEGA Mega Drive/Genesis) | 0:00 |
| 83. | Synyster Graves | 51 | RetroLOLs - Comix Zone / コミックスゾーン [Sega MegaDrive/Genesis] | 22:32 |
| 84. | RatchetGamingAllStars | 49 | Polymega Mega Drive Comix Zone Gameplay | 12:49 |
| 85. | Veritas399 | 47 | Comix Zone: SEGA Mega Drive Classics - PS4 (1995) | 11:00 |
| 86. | Retro Pixel Lizard's Retro Game Dungeon | 45 | Comix Zone (Genesis) - Gameplay | 9:30 |
| 87. | David John-Bores (VidGams) | 43 | Trouble Bruin - Classic Console Conquest Ep. 17 (MD/G) | 20:37 |
| 88. | Vic Zarratt's video pot pourri | 42 | comix zone + cd swap soundtrack | 15:57 |
| 89. | Playing With Ourselves | 42 | Retro Rage: Comix Zone | 12:50 |
| 90. | gamingsoggypantsgeeks | 40 | Comix Zone USA Beta | 4:15 |
| 91. | DefendingTheGame | 40 | Comix Zone PS4 | Worse Way To Die? | Defending The Game | 15:38 |
| 92. | epoc252 | 39 | Comix Zone - Live-Action Film in Development! | 1:12 |
| 93. | Valkyrion | 38 | Traversing the Ink - Panels to Pixels in Comix Zone | 35:07 |
| 94. | Blade Walking Games. BWG. | 38 | Comix Zone - lvl 3.2 walkthrough. The dynamics of the Game let's play. | 9:48 |
| 95. | DuskMink | 38 | Classic Wednesday - Comix Zone | 11:12 |
| 96. | LUKE'S GAMING CHANNEL | 33 | Luke Play's Comix Zone | 26:35 |
| 97. | Mellow Gaming | 28 | Comix Zone - No Continue - Mellow Gaming | 11:08 |
| 98. | Luk0z4d3 | 26 | Sega Megadrive / Genesis classics: Comix Zone* | 12:03 |
| 99. | Freaky Leek | 26 | Comix Zone | Episode 1 | Sega Megadrive Mini | 4:39 |
| 100. | MaxuPlays | 25 | Comix Zone - SEGA Mega Drive Classic | 5:22 |
