| 1. |  Sips | 1,075,842 | Yogscast Play Defcon - Part 2 - Everybody Dies | 17:34 |
| 2. | Introversion Software | 272,875 | DEFCON Trailer 2020 | 1:19 |
| 3. | Shadowhawk | 22,309 | How about a nice game of Chess? DEFCON Livestream | 2:00:44 |
| 4. | DoMiNaToR | 19,584 | Big 2v1 vs TikTok Streamer??? | Defcon FROST | 37:56 |
| 5. | YixelGaming | 11,536 | Defcon Trailer | 1:02 |
| 6. | Luetin09 | 5,287 | DEFCON Everybody Dies | LT (Africa) vs Trev (SA) | 29:58 |
| 7. | GameplayReviewUK | 3,113 | DEFCON - Popular 'Piggy in the Middle' Scenario - Demonstration | 14:35 |
| 8. | TheTricky511 | 2,657 | First Strike Final Hour - Nuke Everyone - Episode 1 (Weekend Wonder) | 29:04 |
| 9. | Ricardos Gaming | 1,325 | ICBM | Would you like to play a game | of Thermal Nuclear War | 43:39 |
| 10. | Gallop Crush | 884 | Defcon Game By Introversion Software | 40:17 |
| 11. | KlingonGamerYT | 782 | DAY 178 - PS1 Style Horror Game | 21:07 |
| 12. | Split Screen | 718 | DEFCON: How About A Nice Game of Chess? | Game Review | 6:32 |
| 13. | A Gamedev Plays... | 552 | DEFCON - Online vs Max-Lony #2 | 29:24 |
| 14. | Royal Coyote | 279 | ICBM GIVE AWAY WINNER ANOUNCMENT | 7:43 |
| 15. | SCARRIOR | 243 | DEFCON - Gameplay | 36:28 |
| 16. | CynicalChinchilla | 170 | DEFCON: Everybody Dies - #2 "The whole world is f**ked!" | 19:29 |
| 17. | MiNameIsJake | 142 | Jake Plays: Defcon (Part 2) | 33:27 |
| 18. | Heiach | 117 | The No Scrub Zone Play Defcon: Everybody dies | 19:48 |
| 19. | Kronenbourg - Let's Plays and Reviews | 100 | DEFCON - Game Review with Gameplay - Part 2 of 2 | 13:44 |
| 20. | Ian Scott | 57 | NUKE WAR GAME | Defcon ☢️ | 9:21 |
| 21. | MarkBetaOne | 35 | DEFCOИ ::: #2006 #Defcon # EverybodyDies #RetroGaming #TheVikingWay #TheScottishWay | 0:00 |
| 22. | Blue Brick Studios | 21 | Bonus Content: A Full Game of DEFCON | 46:33 |
| 23. | Roggor | 18 | DEFCON ONE - Let's Play First Winter (PC Indie Horror Game Gameplay Walkthrough) | 29:27 |
| 24. | Rational Gamers | 11 | I've Not Played Defcon | 18:57 |
| 25. | Teo Games | 6 | DEFCON (with a little phasmo at the end) | 3:48:03 |
