| 2024-03-08 | SAVY WRITES BOOKS | 125,000 | A Full GamerGate Retrospective | DEEP DIVE | 6:01:55 |
| 2024-02-12 | TGM | 268 | We Need To Talk // Depression Quest | 1:21:38 |
| 2023-03-12 | Avenaut | 16,600 | Gamergate saga explained - What was it after all? | 6:29 |
| 2023-03-12 | Saiduck_Tv | 20 | « Depression Quest Playthrough » | 1:34:01 |
| 2023-03-11 | Duke Snukem | 3,270 | Depression Quest IRL DLC - !discord !merch | 5:03:40 |
| 2022-08-02 | Swear Gaming | 78 | Under $10 Games/One & Done: Depression Quest | 1:23:01 |
| 2022-07-05 | Press Play to Jayson | 259 | The Value of Mental Health Games | Press Play to Jayson | 24:36 |
| 2022-06-20 | Spiteful Hopes | 52,500 | Free 5* Accessories, Higher Rates For Acc Summons, Chronic Depression Quest Banners & More | 5:55 |
| 2021-12-14 | Dirac_dydx | 155 | Mental Monday: Bipolar Dude Plays Depression Quest | 1:44:40 |
| 2021-06-07 | SeaShell Shoober | 23 | //Depression Quest Full Game// LIFE SUCKS | 1:07:03 |
| 2021-06-06 | The Gaming Mole: Brad_Ry | 24,300 | Depression Quest - I'm Sorry For Uploading This | 1:35:47 |
| 2020-10-10 | ハンゾウ カザミVT | 225 | World Mental Health Day pt.2 - Depression Quest | 43:22 |
| 2020-07-24 | UnrelatedTherapy | 801 | Depression Quest | 1:40:47 |
| 2020-02-02 | It'sAGundam | 819,000 | Warcraft 3: Reforged Lowest Metacritic Score Ever LOWER than Depression Quest. | 11:28 |
| 2019-12-27 | WahWahQueenMew | 665 | Story Time! ft. Depression- Depression Quest | 1:54:24 |
| 2019-12-07 | EpiDragon | 1,030 | Play Games For Charity: Raising Awareness For Mental Illness #SafeInOurWorld Mature content | 8:07:19 |
| 2019-09-21 | Mikey Films | 699 | THIS GAME GETS REAL | Depression Quest #1 | 8:26 |
| 2018-09-01 | SidAlpha | 114,000 | Dirty Devs: Zoe Quinn Kickstarter Scam Allegations | 10:27 |
| 2018-03-17 | The Edgy Penguin | 3,930 | MEDIA WARS: Video Games (Cold Contempt S1 E7) | 1:12:53 |
| 2018-03-02 | 80% Relatable | 2,430 | Two Queers Play Depression Quest | Get in the Fucking Robot | 1:59:25 |
| 2017-10-21 | Lord Crocosquirrel | 2,380 | Indygo - Depression Quest Gets Pwned | 8:50 |
| 2017-09-13 | Helbeard | 676 | Depression Quest - First Impression Backlog Deathmarch | 16:01 |
| 2017-06-12 | Video Games And The World | 650 | VGATW Latest News - Zoe Quinn vs Tim Soret | 9:05 |
| 2017-04-19 | vodkaowl | 1,590 | I'm dying inside | 0:31 |
| 2017-02-12 | KrazyCries | 1,990 | Krazy Plays Depression Quest PROCEED WITH CAUTION! (P2) | 17:27 |
| 2016-09-26 | TheCrazyEven | 3,090 | CONTROVERSY: Depression Quest | 12:04 |
| 2016-06-06 | PaxashPlays | 385 | Paxash Plays Depression Quest | Hitting a Bit Too Close to Home | 1:14:40 |
| 2016-03-18 | mewlissa | 3,540 | Let's Play: Depression Quest - Final | 12:06 |
| 2015-10-06 | Reel Rejects | 1,460,000 | Dankpression Quest (Part IV - The Final Sad-Down) | 1:05:22 |
| 2015-08-27 | Boneclinks Clips | 12,800 | Depression Quest: A Depression Simulator | 55:57 |
| 2015-08-08 | Ryo | 3,560 | the choices i would of picked if it was really me ( Depression Quest ) | 2:06 |
| 2015-06-21 | DopplerVidya | 120 | Depression Quest - Absolute Garbage | 20:21 |
| 2015-02-25 | nekobun | 500 | Depression Quest - Pt. 5 (Final) | 19:47 |
| 2015-02-03 | JT Vega | 954 | Readings of Depression Quest Reviews on Steam | 3:16 |
| 2014-09-05 | OMGWTFL0LZ | 5,800 | The Is FBI Involved:: StopHarassing Game Developers | 5:42 |
| 2014-08-21 | Gomer | 250 | [Gomer Plays] Depression Quest (Blind) | 37:58 |
| 2014-08-14 | FlutterShaman | 607 | DEPRESSIONQUEST | 3:54 |
| 2014-05-10 | randomfox | 7,110 | Foxeh Struggles To Play Depression Quest | 1:45:16 |
| 2014-04-20 | Errant Signal | 174,000 | Errant Signal - Actual Sunlight + Depression Quest (Spoilers) | 13:09 |
| 2014-01-03 | Pantsless Shorts | 612 | Top 5 Best Games of 2013 | 7:41 |
| 2013-03-11 | M-Pie | 654 | Indie - Depression Quest - More Serious Than I Thought | 33:20 |