| 1. |  Salman Khan | 1,277 | Desperados 3: Sneak, Shoot, and Survive - Mission 1 Gameplay in 1440p | 10:45 |
| 2. | Eagle Eye | 225 | Mission 2 Byers Pass (Running Late on Pay day) | 5:18 |
| 3. | Veteran Wolf | 195 | Desperados III Creative Stealth and Combo Kills | 16:35 |
| 4. | Pee For Pro Walkthrough PFPW | 179 | Desperados III ENDING PC Part 53 | 24:16 |
| 5. | Ghosty Gamer | 152 | Desperados 3 - Mission 4: Until Death Do Us Part Walkthrough | 31:58 |
| 6. | I Playthrough | 152 | DESPERADOS 3 Announce Trailer (New Strategy Game 2019) GamesCom 2018 | 2:01 |
| 7. | GamesTrack | 115 | Top Upcoming New PS4 Games June 2020 | 27:13 |
| 8. | The Gaming Fiesta | 113 | Desperados 3 Walkthrough gameplay Mission 3 part 3 | 8:07 |
| 9. | M.Talha. R | 90 | King OF The West Gameplay MaxGraphics 60FPS + Download Link | 14:00 |
| 10. | RTX ARMY | 87 | DESPERADOS 3 benchmark on gtx 750ti & i5 3570 ultra settings | 7:13 |
| 11. | Ghost 47 | 46 | Desperados 3 - Mission 5 The Magnificent Five (Desperado, No Save) | 43:05 |
| 12. | NotWalker | 34 | I'd say we are even now... Desperados 3 | 10:02 |
| 13. | Tekken Gujrat | 22 | Flint - Treasure of Oblivion - Reveal Trailer | PS5 Games | 1:29 |
| 14. | REAL DEPANTHERIX YT | 20 | DESPERADOS 3 Gameplay Walkthrough Demo Gamescom 2018 (New Wild West Strategy Game 2019) | 19:14 |
| 15. | GMiXinG & Printech | 19 | Desperados III 3 pc gaming | 4:11 |
| 16. | Gamershub | 17 | Desperados III - Hector Mendoza Trailer | 1:37 |
| 17. | NoobSasaiBot | 14 | War Hospita Хотели Отдать Дань Уважения, но Вышла Как Всегда Нудятинаl!! | 1:51:46 |
| 18. | NEXT GEN | 14 | Desperados III Free Baron's Challenges Update #1 Trailer | 0:57 |
| 19. | Game Steam | 6 | Desperados III - Game Play Demo : Game Steam | 9:47 |
| 20. | TUFAIL | 5 | DESPERADOS Reveal Trailer New Western Game YouTube | 2:01 |
| 21. | GameShow Channel | 4 | KING OF THE WEST ANDROID AND IOS GAMEPLAY | 10:29 |
| 22. | Trends-And-Shifts | 1 | Desperados III - Launch Trailer - PlayStation 4. | 3:55 |
