| 1. | Tailz64 | Two-Tailed Playthrough - Ghostbusters (Sega Genesis) | 42,477 | Let's Play |
| 2. |  Rental Rewind Gaming | Ghostbusters Playthrough (SEGA GENESIS/MEGA DRIVE) | 35,471 | Let's Play |
| 3. |  lame gag | Ghostbusters [Colour Hack] | SEGA Mega Drive / Genesis | MiSTer Playthrough | 2,896 | Let's Play |
| 4. | VideoGameStupid | Let's Play - Ghost Busters (SEGA) Part 2 | 2,823 | Let's Play |
| 5. | Oliver Harper's Lets Play Retro | GHOSTBUSTERS (Mega Drive / Genesis) Let's Play Retro | 1,699 | Let's Play |
| 6. | SkidRowTrash | Ghostbusters (Sega Genesis) - Let's Play It! | 1,542 | Let's Play |
| 7. |  PugmanPlays | Ghostbusters. (Megadrive / Genesis) Complete Playthrough. Co-Op Commentary. Part 1. HD Video | 1,222 | Let's Play |
| 8. | Eric Corp Incorporated | Ghostbusters (Genesis / Mega Drive) Playthrough Redux | 676 | Let's Play |
| 9. |  SEGA MD2 | Ghostbusters [RUS] (Sega Genesis) - Longplay | 656 | Let's Play |
| 10. | Let's Play With Brigands | Ghost Busters NES (Full Playthrough) | 588 | Let's Play |
| 11. | Media Pool | Ghostbusters (genesis) Game Playthrough Retro game | 466 | Let's Play |
| 12. | EctoTron1 | Let's Play Ghostbusters (Mega Drive) | 402 | Let's Play |
| 13. |  BRGKasumi77 MAIN CHANNEL | Ghostbusters Remastered (The Real) (Ghostbusters NES Hack) Playthrough with cheats | 385 | Let's Play |
| 14. | Eric Corp Incorporated | Ghostbusters (Genesis / Mega Drive) Playthrough | 268 | Let's Play |
| 15. | OnMyPS3 | Ghostbusters MSU-MD + Color Fix [GEN/MD] PS3 PKG Playstation 3 | 248 | Let's Play |
| 16. |  SpielSatzFail | Die Geister der Vergangenheit | Ghostbusters #1 [Mega Drive] Let's Play deutsch | 239 | Let's Play |
| 17. |  Kozma Games | Ghostbusters - MEGADRIVE - ESSE JOGO ENVELHECEU MAL? | 133 | Let's Play |
| 18. |  TheBrunoBits | #45 Ghostbusters | Mega Drive (Playthrough + Ending) | 63 | Let's Play |
| 19. | SpielSatzFail | Das ist also dieses Downtown | Ghostbusters #4 [Mega Drive] LP deutsch | 53 | Let's Play |
| 20. | SpielSatzFail | Einsatz im Brennpunkt | Ghostbusters #2 [Mega Drive] LP deutsch | 52 | Let's Play |
| 21. |  Rob64 Gaming | Ghostbusters - NES LetsPlay Deutsch | 51 | Let's Play |
| 22. | Kozma Games | Dead End Job - GHOSTBUSTERS ROGUELIKE (Gameplay em Português PT-BR) #DeadEndJob | 46 | Let's Play |
| 23. | Retro Mega Muffin | Ghostbusters [1990, Mega Drive] Special Edition Rom Hack Winston Playthrough ~Streamed 2023.05.09~ | 43 | Let's Play |
| 24. | SpielSatzFail | Die sind mir hochhaus überlegen | Ghostbusters #3 [Mega Drive] LP deutsch | 41 | Let's Play |
| 25. | SpielSatzFail | Ein Morgenmuffel aus dem Reich der Finsternis | Ghostbusters #5 (Ende) [Mega Drive] LP deutsch | 34 | Let's Play |
| 26. | SpiritGames | GhostBusters Sega Genesis Full Playthrough | 29 | Let's Play |
| 27. | LongPlay | Longview plays Ghostbusters - 24th October 2020 | 29 | Let's Play |
| 28. | SuperGeoffGoodGamer | Geoff Good Gamer plays Ghostbusters [Sega] | 22 | Let's Play |
| 29. | Mellow Gaming | MG Plays: Ghostbusters - Where's Winston?! | 19 | Let's Play |
| 30. | Pelador Plays | Pelador Plays Ghostbusters | 12 | Let's Play |
| 31. | Jkun Prime | Jkun Plays - Ghostbusters Sega Genesis - Full Playthrough | 9 | Let's Play |
| 32. | The MrMatthews Gaming Archive | Ghostbusters (Sega Genesis) ~ ALPHANERD SPEEDRUN CHALLENGE | 8 | Let's Play |
