| 1. |  Vennori | No Swear Electric Challenge "Give Up" Gameplay (Shock Collar Challenge) | 220 | |
| 2. | JamiUwU | LAW WON'T GIVE IT UP! One Piece Episode 951 Reaction + Review! | 212 | Review |
| 3. | lonniedos | GIVE IT UP! (iPhone Gameplay Video) | 116 | Let's Play |
| 4. | Just Jammin' | FIRST TIME HEARING Marvin Gaye - Got To Give It Up Reaction | 103 | |
| 5. | Cassiopeia | Sean Paul - Give It Up To Me (Lyrics) ft. Keyshia Cole | 72 | |
| 6. | ZerrekTheDog | COLLAB PART FOR: BrubSFM (GIVE IT UP) | 57 | |
| 7. | Steve Shives | It's Lent, So Give It Up! | The Whirlpool | 46 | Let's Play |
| 8. | Just Jammin' | FIRST TIME REACTING TO FIRST TIME REACTING TO The Jacksons - Give It Up Reaction | 39 | |
| 9. | Just Jammin' | Bone Thugs-n-Harmony - Can't Give It Up Reaction | 36 | |
| 10. | Just Jammin' | Aaliyah - Got To Give It Up Remix Reaction | 30 | |
| 11. | ChilledGemini99 | (Intro) Give It Up!: Chilled's Automotive Show! （イントロ）Give It Up！：チルドの自動車ショー！ | 24 | |
| 12. | GOD LYRICS | Sean Paul - Give It Up to Me (Tiktok Remix) (Lyrics) from ya look inna mi eye gal me see you want me | 18 | |
| 13. | Just Jammin' | FIRST TIME HEARING Kool & The Gang - Give It Up REACTION | 17 | |
| 14. | NixziiiⓋ | GIVE IT UP! #cuphead #shorts #cupheadandmugman #cupheadmeme #fnaf #thecupheadshow #cupheadps4 #short | 16 | Show |
| 15. | Just Jammin' | Mobb Deep - Give It Up Fast Reaction | 11 | |
| 16. | CrimsonAdri | 【GMV】 Give It Up - Harley/Selina/Ivy | 11 | |
| 17. | Nearch_44 | Give it up for BAD GATEWAY! || Ai Girlfriend Simulator | 10 | |
| 18. | The Renaissance Nerd | Kathleen Kennedy's Contract At Lucasfilm Renewed Through 2024! She'll Never Give It Up! | 8 | |
| 19. | Savage Moses | GIVE IT UP FOR THE BLACK N MILD BANDITS 🤣 THEY 🔥🔥🔥 THO #savagemoses | 8 | |
| 20. | immabotbtw • 114k views • 2 days ago | Let me show you right now before you give it up... | 5 | |
| 21. | Just Jammin' | Sade - Give It Up Reaction | 5 | |
| 22. | Maximumandroid - Just Good Games | Give It Up! 3 Android Gameplay (Beta Test) | 4 | |
| 23. | CTKaraoke | Dance Central 3 - (When You Gonna) Give It Up To Me FC 100% Hard | 4 | |
| 24. | ZNAGASHINO | Give it up Gta5 ai Madrazo | 4 | |
| 25. | SWAY'S UNIVERSE | Skyzoo Performs "Give It Up" on #SwayInTheMorning's Live In-Studio Concert Series | Sway's Universe | 3 | |
| 26. | Just Jammin' | FIRST TIME HEARING Arabesque - Give It Up REACTION | 3 | |
| 27. | Beat Saber Anime | Bokutachi wa Benkyou ga Dekinai ED (We Never Learn) 「Never Give It Up!!」 by Study | OSU Anime | 3 | |
| 28. | HighLevelz | Give It Up 4-Dash - All Levels - Gameplay Android, iOS | 2 | |
| 29. | REPOSITORY #140 | Chad Dubz - Nah Give It Up | 2 | |
| 30. | PCGameIt | Give It Up! Plus - Reflex Rhythm Game | PC Port Gameplay [1080p HD] | 2 | |
| 31. | Viking6346 | Sony lovers are hypocrites! Stop complaining and just give it up. #gaming #upcominggames #gamer | 2 | |
| 32. | SimplyTwoDudes | Berywam - Give It Up | REACTION | 2 | |
| 33. | ThatGuyQuizz | WHEN WILL PLANKTON GIVE IT UP! | Plankton's Plan | 1 | |
