| 1. |  Smooth McGroove | Mega Man 2 - Dr. Wily Stage Acapella | 12,978 | |
| 2. | Gamechamp3000 | VG Myths - Can You Beat Rockman 2 Without Getting Hit? | 5,966 | |
| 3. | GameGrumps | Mega Man 2: Ash Man - PART 3 - Game Grumps | 5,230 | |
| 4. | GameGrumps | Mega Man 2: Death By Bubble - PART 1 - Game Grumps | 4,350 | |
| 5. | Smosh Games | MEGA MAN (Honest Game Trailers) | 4,034 | Preview |
| 6. |  Jael Peñaloza (Jakei) | SPOILER ALERT | 3,844 | |
| 7. |  SiIvaGunner | Wood Man Fusion Collab | 3,328 | |
| 8. | Scykoh | Mega Man 2 - Glitchfest | 2,999 | |
| 9. | GameGrumps | Mega Man 2: Blind Lava Jumps - PART 2 - Game Grumps | 2,880 | |
| 10. | brentalfloss | Mega Man 2 TITLE With Lyrics - brentalfloss | 2,789 | |
| 11. | GameGrumps | Mega Man 2: Heat Man the Series - PART 5 - Game Grumps | 2,716 | |
| 12. | Smooth McGroove | Mega Man 2 - Metal Man Acapella | 2,550 | |
| 13. |  AssopraFitas | A ORDEM DOS CHEFES LOUCOS | 2,463 | |
| 14. | GameGrumps | Mega Man 2: Finale - PART 11 - Game Grumps | 2,412 | |
| 15. | GameGrumps | Mega Man 2: Dinosaur Loogie Fun - PART 6 - Game Grumps | 2,405 | |
| 16. | GameGrumps | Mega Man 2: Quickly, Now - PART 4 - Game Grumps | 2,175 | |
| 17. | SiIvaGunner | Wood Man Stage - Mega Man 2 | 2,125 | |
| 18. | GameGrumps | Mega Man 2: Wily's a Jerk - PART 7 - Game Grumps | 2,051 | |
| 19. | Songe | Mega Man 2 - Dr. Wily Stage 1 cover 【Songe】 | 2,037 | |
| 20. | GameGrumps | Mega Man 2: Crash and Burn - PART 9 - Game Grumps | 1,978 | |
| 21. | GameGrumps | Mega Man 2: Too Many Graphics - PART 8 - Game Grumps | 1,859 | |
| 22. | ColdBrew697 | Bit Brigade performing Mega Man 2 at MAGFest X | 1,788 | |
| 23. | RetroSFX Mashups | 'Terminator 2' dubbed with MEGA MAN 2 game sounds! | RetroSFX Mashups | 1,692 | |
| 24. | AssopraFitas | O GAME MAIS DIFÍCIL E DIVERTIDO DA INFÂNCIA | 1,675 | |
| 25. | Marcos Kazan | Mega Man 2 Dr. Wily´s Castle Theme on the guitar. | 1,669 | |
| 26. | GameGrumps | Mega Man 2: Tangerine Sunsets - PART 10 - Game Grumps | 1,663 | |
| 27. | Taylor Davis | Dr. Wily's Castle (Mega Man 2) - Violin Cover - Taylor Davis | 1,435 | |
| 28. | Cinemassacre | Mega Man 2 (NES Video Game) Part 2 - James & Mike Mondays | 1,350 | |
| 29. |  VixyNyan (ヴィクシ) | Mega Man 2 Atari DeMake (PC) Game Clear~ | 1,334 | |
| 30. | chuggaaconroy | lets play megaman2 prat 1 (APRIL FOOLS) | 1,309 | |
| 31. | Cinemassacre | Mega Man Ultra (NES) James & Mike Mondays | 1,298 | |
| 32. | あまみん | 少女達のお泊り実況～ロックマン２（後編）～ | 1,204 | |
| 33. | J's Reviews | Is Mega Man 2 Overrated? | 1,200 | |
| 34. | SomecallmeJohnny | Johnny vs. Mega Man 2 | 1,177 | |
| 35. | Cinemassacre | Mega Man 2 (NES Video Game) Part 1 - James & Mike Mondays | 1,157 | |
| 36. | xDEFCONx | Megaman 2 - Wood Man (xDEFCONx Remix / Remake) | 1,135 | |
| 37. | dookieshed | Top 10 Coolest Mega Man Power-ups of all time! | 1,108 | |
| 38. | St1ka | The Brazilian Mega Man | St1ka's Retro Corner | 1,102 | |
| 39. | Nathaniel Bandy | How Mega Man 2 TRIGGERS You! | 1,089 | |
| 40. | Jcs779 | ［FC/NES］ Rockman 2: All Quick Man | 1,063 | |
| 41. |  MichaelBtheGameGenie | Top 10 NES "Nintendo" Games | MichaelBtheGameGenie | 1,048 | |
| 42. |  Pepe el Mago Juega | La Segunda Aventura de Mega Man !! - Mega Man 2 con Pepe el Mago (#1) | 999 | |
| 43. | Bumbles McFumbles | Robot Masters Vs Net Navis - Who Has The Better Design? [Bumbles McFumbles] | 972 | |
| 44. | 8-bit Music Theory | How To Write A Song From The Mega Man 2 Soundtrack | 967 | Guide |
| 45. | Pepe el Mago Juega | Los Rayos de LA MUERTE !! - Mega Man 2 con Pepe el Mago (#2) | 880 | |
| 46. |  Crimson Diex | Top 10 Robots Masters Mas Difíciles De Megaman Según Yo | 866 | |
| 47. | Epic Game Music | Mega Man 2 Dr. Wily Stage 1 (Music Video) // Epic Game Music | 862 | |
| 48. | Stop Skeletons From Fighting | Mega Man 2's Brilliant & Historic Ending | Gettin' Super Nerdy [SSFF] | 859 | |
| 49. | F.A.P Bros | el JUEGO mas BASADO de Megaman 🍋| Megaman 2 REMAKE [FAP REVIEW] | 844 | Review |
| 50. | U Can Beat Video Games | #Megaman2 #MegaManII #RockMan2 #NES Mega Man 2 - NES - Ultimate Guide! (Normal, Zipless) | 814 | |
| 51. | Boundary Break | Off Camera Secrets | Mega Man Series - Boundary Break ft. GameXplain | 813 | |
| 52. |  MatsukeN / マツケん | ロックマン2メドレーをファミコン実機音源で合奏してみた Mega Man 2 Medley / NES BAND 30th Live 2019 | 808 | |
| 53. | Old Gamer - Jogatina Clássica | NES Longplay Mega Man 2 | 804 | |
| 54. | OverClocked ReMix: Video Game Music Community | OC ReMix #1702: Mega Man 2 'Nuclear Flash' [Flash Man] by Juan Medrano & zircon | 793 | |
| 55. |  Ryuko Shion | LA HISTORIA DE MEGA MAN SE ARRUINÓ EN AMÉRICA | Ryuko Shion | 791 | |
| 56. | LetsPlay | Megaman 2 SPEED RUN RACE - Let's Play | 790 | Let's Play |
| 57. | Lumpy Touch | Realistic Mega Man 2 (enhanced with AI) | 781 | |
| 58. | GaMetal | Wood Man Stage (Mega Man 2) - GaMetal Remix | 778 | |
| 59. | Niko's 8BitStereo | Mega Man 2 (NES) Soundtrack - 8BitStereo *OLD MIX* | 751 | |
| 60. |  MechaShadowREV | Фанатские игры по Mega Man (Часть 2) - MechaShadowREV | 719 | |
| 61. | Maximilian Dood | Mega Man 2 KICKED MY ASS - Full Playthru | 708 | |
| 62. | Cinemassacre | Cinemassacre Animated - Everything's a Skull - Mega Man 2 | 685 | |
| 63. | CouchSoup | Nolan North and Troy Baker Mega Fail at Playing Mega Man 2 | 652 | Let's Play |
| 64. | ゆっくり小町 | エアーマンが倒せない 全力でツッコんでみた！ | 635 | |
| 65. |  TheLegendofRenegade | Mega Man 2 - Wood Man Stage (Sega Genesis Remix) | 633 | |
| 66. | Bulby | Wood Man 16 Bit (SNES Mega Man X Remix) - Mega Man 2 | 629 | |
| 67. | Erin Plays | Mega Man 2 (NES) Robot Masters - Erin Plays | 628 | |
| 68. | Pikasprey Yellow | Mega Man 2: The Sequel That Saved the Series - Pikasprey | 627 | |
| 69. | KHAce | Mega Man 2 Remade in Super Mario Maker | 616 | |
| 70. | Russian Geek | Пинг Раздражения - Кто Кого? (401) | 603 | |
| 71. | RoahmMythril | Mega Man 2 - Quick Man Perfect Run | 600 | |
| 72. | Pepe el Mago Juega | MEGA MAN VS EL DRAGON DE WILY !! - Mega Man 2 con Pepe el Mago (#3) | 595 | |
| 73. | retsupurae | Crappy Pasta VI: My Girlfriend is Mega Man 2 | 578 | |
| 74. | GBelair | Mega Man 2 (NES) Music - Boss Battle | 576 | |
| 75. | あまみん | 少女達のお泊り実況～ロックマン２（前編）～ | 575 | |
| 76. | bobvids | Masculist Man | 570 | |
| 77. | GBelair | Mega Man 2 (NES) Music - Wily Fortress 1 | 570 | |
| 78. | Nestalgica | Mega Man 2 - Wood Man theme (2017 version) [METAL COVER] | 564 | |
| 79. | GBelair | Mega Man 2 (NES) Music - Quick Man Stage | 549 | |
| 80. | dookieshed | Four Ways Mega Man Perfected the Side-Scroller | 545 | |
| 81. | Arcus | Mega Man 2 NES speedrun in 30:33 by Arcus | 542 | |
| 82. | GBelair | Mega Man 2 (NES) Music - Flash Man Stage | 541 | |
| 83. | Big Ole Words | Strange Secrets Hidden in NES Games (Nintendo Entertainment System) | 533 | |
| 84. | SiIvaGunner | Wood Man Stage (Birthday Mix) - Mega Man 2 | 529 | |
| 85. | Nintendo Unity | Mega Man 2 - Boss Rush (All Boss Fights, No Damage) | 526 | |
| 86. | Power Guy | I Have to Beat Megaman 2!! | 523 | |
| 87. | TheLegendofRenegade | Mega Man 2 - Metal Man Stage (Sega Genesis Remix) | 501 | |
| 88. | TheLegendofRenegade | Mega Man 2 - Crash Man Stage (Sega Genesis Remix) | 498 | |
| 89. | GBelair | Mega Man 2 (NES) Music - Bubble Man Stage | 497 | |
| 90. | IGN | Live Mega Man 2 Speedrun - Bit Brigade @ MAGFest X | 492 | |
| 91. | Kane TV | MEGA MAN 2 - WILY VOLTOU MAIS BUCHA AINDA | 480 | |
| 92. |  Mundo N | TOP 5 - Los mejores juegos de Mega Man | 478 | |
| 93. | PinkKittyRose | Mega Man 2 - Quick Man's Stage | 475 | |
| 94. | GBelair | Mega Man 2 (NES) Music - Metal Man Stage | 472 | |
| 95. | ProJared Plays! | Difficult Mode Cause I Don't Suck │ Mega Man 2 #1 | 468 | |
| 96. |  Urisia Beropen | TOP 10 - Musicas similares en los videojuegos | 461 | |
| 97. | Jcs779 | ［FC/NES］ Rockman 2: Everlast | 457 | |
| 98. | RushJet1 | Mega Man 2 Cover Playthrough [60FPS] | 455 | |
| 99. | niefong | The Advantage plays Mega Man 2 Flashman | 453 | |
| 100. | Russian Geek | Mega Man 2 - GameShelf #27 | 451 | |
