| 1. |  ClementJ64 | 542,027 | Let's Play Mega Man 5! (Part 6) | 9:59 |
| 2. |  DSPGaming | 210,194 | Megaman 5 playthrough pt20 (final) | 6:07 |
| 3. | NintendoComplete | 164,084 | Mega Man 5 (NES) Playthrough - NintendoComplete | 1:08:57 |
| 4. |  MET | 128,990 | Mega Man 5 Guitar Playthrough (COMPLETE) | 1:12:40 |
| 5. |  EpsilonGamex | 111,880 | MEGAMAN 5 MINI SERIE #5 EpsilonGamex | 13:06 |
| 6. |  GermanLetsPlay | 101,301 | MEGAMAN 5 - #09 - WILY MACHINE NO. 5 & WILY CAPSULE NO. 2 ☆ Let's Play Megaman 5 | 7:59 |
| 7. | Naka Teleeli | 50,618 | Let's Play Mega Man 5 [8] Finale | 22:56 |
| 8. | Kinda Funny Games | 35,807 | Mega Man 5 Entire Game Full Playthrough - Kinda Funny Plays | 1:17:45 |
| 9. | The Quarter Guy | 32,963 | Let's Play Mega Man 5 - Road To Mega Man 11 - Part 31 - Beating Wily Yet Again | 14:33 |
| 10. | World of Longplays | 29,304 | NES Longplay [469] Rockman 5: Blues no Wana!? | 1:15:40 |
| 11. | WarsongLeaders | 22,928 | Let's Play (Español) - Megaman 5 (Fin) | 9:53 |
| 12. | Nintendo451 | 22,748 | Mega Man 5 Title w/ Lyrics ALPHA | 1:50 |
| 13. | mtgxerxes | 15,308 | Lets Play Mega Man 5 (Part 4 FINALE) B.O.N.D. 'Game Over' | 26:52 |
| 14. | GameXplain | 13,367 | Ash Plays Mega Man 5! | 1:28:58 |
| 15. |  VCDECIDE | 12,320 | [Demo] Mega Man 5 (Sega Genesis vs PlayStation) Side by Side Comparison | 5:47 |
| 16. | DSJ Brigade | 11,167 | Let's Play Megaman 5 016: Beat! I Choose You! | 7:49 |
| 17. | OGRagebreak Gaming | 9,104 | Beat Rush!👊| Let's Play Mega Man 5 #08 (NES) [Finale!] | 11:37 |
| 18. | ZetaPlays | 8,873 | Let's Play Mega Man 5 04 - We Saved The World Or Something | 30:53 |
| 19. | DarkEvil87's Longplays | 8,554 | Mega Man 5 - DarkEvil87's Longplays - Full Longplay (NES) | 1:08:51 |
| 20. | Mettbaron | 8,162 | Let's Play Mega Man 5 (GameBoy) [9] - R-Type mit Rush | 25:42 |
| 21. | Jassy666 | 7,635 | Let's Play Mega Man Legacy Collection [Mega Man 5] - #33 - Massenweise Bosse | 33:07 |
| 22. | TMoneybags92 | 7,617 | Mega Man 5 Protoman Edition [Playthrough] | 1:02:25 |
| 23. | KainXiorcal | 6,172 | Megaman X Zero Goes Maverick - Gravity Beetle playthrough (MegaMan 5 hack) | 4:48 |
| 24. | Gameplay and Talk | 5,462 | Real NES games in COMPOSITE via RetroTINK-5X (variety stream) | Gameplay and Talk Live Stream #510 | 8:55:20 |
| 25. | NRWBoy18 | 4,882 | Lets Play - Mega Man 5 (Deutsch) [Teil 16] | 10:22 |
| 26. | DMF WorldGames | 4,584 | Megaman 5 (100%) - Parte 7 FINAL "Humilhando o Wily e final de LP" | 8:33 |
| 27. |  HellfireComms | 4,467 | Mega Man 5 playthrough [Part 1: Proto Man's Grand Plan] | 16:26 |
| 28. | Quadraxis14 | 4,336 | Let's Play Mega Man 5 10 - Mega Man - 5, Wily - 0 | 9:30 |
| 29. | samuraikarasu | 3,766 | Let's Play Mega Man 5 Part 8 | 6:28 |
| 30. | Megabeatman's Archive Zone | 3,766 | Let's Play Mega Man 5! (Part 8) | 11:04 |
| 31. | Cornshaq | 3,688 | MEGA MAN 5 (PLAYSTATION 1) - PLAY IT THROUGH | 58:48 |
| 32. | Marlongamingnation | 3,657 | PS5 Showcase Rumor - WB No More AAA Games - 5 New PS5 Games - New Capcom Showcase | 1:54:47 |
| 33. | zugzuj | 3,598 | Lets Play Mega Man 5 Vol.9 (German) [Blind] - FINALE!!! | 18:35 |
| 34. |  Yukun ch. | 3,388 | 桃鉄16 ②# 100 完結！100年エンディング回【桃太郎電鉄16 北海道大移動の巻!】♪桃鉄よ永遠なれ! 釧路と名瀬港に到着 PlayStation2 切り抜き鉄道 BGM | 28:48 |
| 35. | AltimaMantoid | 3,281 | Let's Play: Mega Man 5 - Part 9 - Proto Man's True Intent (End Credits) | 19:28 |
| 36. | BikdipOnABus | 3,168 | Regarding My Upcoming LPs / Rockman 5 Endless / Random Contest | 9:12 |
| 37. | LordVucious | 3,118 | Mega Man 5 Playthrough (w/Commentary) Part 7/7: Beat, Hide and Seek Gamebreaker | 10:39 |
| 38. | Newfie Bangaa | 2,320 | Let's Play Rockman 5: Wily's Dream Space #01 - Familiar Tunes | 8:39 |
| 39. | JadePharaoh | 2,066 | Jade Plays: Megaman 5 GB (part 6) | 12:02 |
| 40. |  Erik Årman | 1,970 | Mega Man 5 (No Damage) | 1:23:45 |
| 41. |  AyorSaeba | 1,922 | [Let's Play] Mega Man 5 (NES)(Part 2/2) | 59:08 |
| 42. | lothrazar | 1,600 | Let's Play Megaman 5 #15: Rescue | 9:13 |
| 43. |  Kawaii Games | 1,510 | Mega Man 5 [NES] Longplay Walkthrough Playthrough Full Movie Game [4K60ᶠᵖˢ UHD🔴] | 1:19:09 |
| 44. | GigaBoots | 1,418 | MegaMan 5 Casual Playthrough Livestream | 2:26:38 |
| 45. | Satoshi Matrix | 1,391 | PlayStation 2 Classics 030 - Megaman Anniverary Collection Part 5: Megaman 5 | 18:29 |
| 46. | Gooner | 1,379 | Let's Play Mega Man 5 Part 9: Gyro Man [BLIND] (German) | 12:27 |
| 47. | TheMartianGeek | 1,250 | Let's Play Mega Man 5 - Part 16: Mega Man vs. Wily Machine | 10:23 |
| 48. | Ruby Omega | 1,244 | Casual Genocide - Mega Man 5 Protoman's Revenge - 15 | 15:05 |
| 49. |  fluojn | 1,234 | Let's Play eli pelataan: Mega Man 5 | 1:46:50 |
| 50. | Keglton | 1,233 | Best of Das MirkoLP - MEGA MAN 5 - DasMirkoLP Ausraster MegaMan V | 7:52 |
| 51. | MysteriousJG | 1,223 | Let's Play Mega Man 5 (PS4 Collection) Part 16: Finale | 29:24 |
| 52. | Kinjo Game Channel 【Retro Games Playthrough】 | 1,200 | 【ファミコン】 ロックマン5 ブルースの罠！？ OP～ED (1992年)【FC クリア】【Nintendo (NES) Megaman 5 Playthrough (Full Games)】 | 56:34 |
| 53. | Termos de Urso | 1,111 | Let's Play com o Amer: Mega Man V | 1:06:01 |
| 54. | Mineyl | 1,063 | Megaman 5 "Gadgeteer" Playthrough (Part 6/6) | 6:34 |
| 55. | Videoman1443 | 1,007 | Hitler Plays Mega Man 5 Part 1 | 5:53 |
| 56. | VTuber Zeromaster & Power Plays | 898 | Let's Play Megaman 5 - Part 9: STARCRASH NOT Starcraft! | 14:39 |
| 57. | TheJonnyKage | 870 | Let's Play Mega Man 5 part 6: Beat This | 12:57 |
| 58. | Ethervil | 827 | Let's Play Rockman 5: Air Sliding - #3: Air Sliding to Victory (LIVE) | 32:13 |
| 59. | Silver | 820 | Let's Play Mega Man 5 (Overload 3/Blind/German/Finale) Folge 30 Mega Man VS Yuno | 15:51 |
| 60. | FCPlaythroughs | 809 | Mega Man 5 (NES) playthrough ~Longplay~ | 1:02:12 |
| 61. | Robin | 767 | A Look Back at Let's Play Mega Man 5 / V | 5:22 |
| 62. | DasZockIchJetzt aka. Tyler85 | 760 | Let's Play MegaMan 5 (NES) GERMAN Part 9 - Finale (wie immer) | 19:19 |
| 63. | Chay Plays | 729 | Carmine Plays Mega Man 5 Episode 6 [FINALE] | 8:18 |
| 64. |  Mute safeZone | 723 | Easiest Willy Machine Fight Ever!! - [NES] MEGA MAN 5 🤫 Finale | 28:07 |
| 65. | Refresh Gaming | 712 | Lets Play Mega Man 5 (Pacifist): Part 16 - Finale | 4:47 |
| 66. | CountyLineGaming | 701 | [Series] Let's Play Mega Man 5 16: Dr. Wily | 9:50 |
| 67. | Boomerang78 | 693 | Mega Man 5 Playthrough #09 - Proto Castle 1 | 3:32 |
| 68. |  BRGKasumi77 MAIN CHANNEL | 690 | Let's Play: Mega Man 5 (With Cheats) | 53:54 |
| 69. |  JoshKall Plays | 673 | Mega Man 5 - Let's play Part 5(finale): Forshadowing | 21:36 |
| 70. | Nintendo Addict | 671 | Mega Man 5 | Live Blind Full Playthrough | 3:12:17 |
| 71. | Autumchild | 600 | Let's Play Mega Man 5 [7] Finale | 18:42 |
| 72. |  [TH]Sticky! | 578 | [NES] Rockman 5 - Full Playthrough No Death No Damage | 57:57 |
| 73. | 4-8Productions | 555 | Let's Play Megaman 5 EP 7: The Letter of the Day is: "G" (death_unites_us) | 17:57 |
| 74. | Kenshin1913 | 536 | Let's Play Mega Man 5 (part 1) | 10:29 |
| 75. | AmitDabydeen | 527 | Mega Man Robot Master Mayhem 3.1 MUGEN Playthrough with Dark Man (4K/60fps) | 36:33 |
| 76. | DeadZergling | 519 | Let's Play Megaman 5 BLIND Episode 07 | 37:58 |
| 77. | Nicklensean (Videogame Piano Covers & Remixes) | 504 | Dark Man (Updated Piano Cover) - Mega Man 5 | 2:05 |
| 78. | Lord N-Zo | 451 | Mega Man 5 NES | No Death Playthrough | 1:10:27 |
| 79. | The Retro Challenger Ⓥ | 449 | Mega Man 5 (NES) Buster only Speedrun - Without dying and NO E-Tanks | 51:52 |
| 80. |  Kisae | 417 | [Let's Play 1700 Abos] Mega Man 5 (3/3) | 1:28:06 |
| 81. | TopKirby8305 | 416 | TK's Lets Play: Megaman 5 (NES) [HQ] [Part 1] | 13:07 |
| 82. | GM_Darius | 412 | Let's Play Mega Man Anniversary Collection (Mega Man 5) |21| Nefarious Dr. Wily! Again! | 21:27 |
| 83. | Ominouslionheart | 411 | Let's Play Mega Man 5 Part 5 {Final Boss and Credits} | 7:35 |
| 84. | WolfBiteLP | 380 | Let's Play Mega Man 5 (German|Finale) Part 13 - Mehr Energie! | 18:54 |
| 85. | Late Night Mega | 352 | Let's Play MaGMML 48 Hour part 73 - Who's A Fan Of Soccer? | 12:38 |
| 86. | Stardustwarrior33 | 352 | Lets Play Megaman 5 - Part 6 Deutsch/German - Ende gut alles gut | 12:16 |
| 87. | Let's Play With Brigands | 349 | Let's Play Mega Man 5 (Full Playthrough) | 2:04:42 |
| 88. | MegaZeroX Gaming | 343 | Mega Man 5 playthrough part 16: Wily stage 4+ending | 8:31 |
| 89. | SCKnuckles2 (SCKnuckles) | 339 | Let's Play Mega Man 5 Part 14 Finale | 7:59 |
| 90. | Honki Tonk | 328 | Lets Play Mega Man 5 (NES) (Blind) | 3:49:49 |
| 91. | Mchan338 | 325 | Let's Play! - Mega Man 5 - Part 16: Dr. Wily [Stage 4] | 10:12 |
| 92. | MacDaddyNook | 317 | Mega Man 5 Playthrough Part 12: Proto Man Castle Stage 4 | 4:12 |
| 93. |  steg140 | 308 | Rockman 5 Protoman stage 1 playthrough (Dark Man 1) - Perfect Run/No Special Weapons | 3:05 |
| 94. | rynogt4 | 304 | Mega Man 5 (NES/XB1) 100% Let's Play | 2:43:55 |
| 95. | SonKnuckLP | 301 | Let's Play Mega Man 5 - FINALE - Game Is Beat | 23:21 |
| 96. | WaterExodus | 289 | Nintendo Power - Mega Man 5 Ep. 8 | 12:19 |
| 97. | GameShampoo | 281 | Mega Man 5 LP Ep 16 Dr Wily Stage 4 | 13:31 |
| 98. | ST2K | 281 | Let's Play: Mega Man 5 (NES) - Part 3 | 16:22 |
| 99. | Svenchen87 | 270 | Let's Play Mega Man 5, Part 10: The End | 21:36 |
| 100. | RichterBelmont12 | 270 | Let's Play Mega Man 5 05: Dr. Willy's End | 30:20 |
