| 1. |  MarlinsBaseball | 78,754 | MLB 06: The Show (Florida Marlins Season) Season Results + Credits | 6:48 |
| 2. | Healy6 | 43,125 | Seeing if MLB 06: The Show is as good as I remember... | 21:06 |
| 3. | KAHOS 3.0 | 40,644 | 🔴 KAHOS' BIRTHDAY ! ! ! ( LIVE ) ORIOLES ( 47 - 50 ) VS. YANKEES ( 85 - 12 )🔴 PART 2 | 0:00 |
| 4. | IGN | 30,996 | MLB '06: The Show PlayStation 2 Trailer - Official | 1:22 |
| 5. | igcompany | 26,067 | MVP 06: NCAA Baseball - PS2 Gameplay (4K60fps) | 14:43 |
| 6. | Timmii Gaming Channel | 10,575 | OPM Issue 111 - PS2 2006 (Inside The Game O.A.R.) | 0:00 |
| 7. | Stream's YouTube Channel | 8,862 | Collecting Every NA PS2 Game - MLB 06': The Show (PS2 Gauntlet #2) | 38:47 |
| 8. | Emmdotfrisk | 6,336 | MLB 06 The Show's Career Mode is DIFFERENT | 33:04 |
| 9. | Gyvi World | 6,297 | The Greatest Baseball Game EVER! This made MLB! | 21:17 |
| 10. | PS2SPORTSINFOSTATION | 5,680 | MLB The Show 06 St. Louis Cardinals vs Detroit Tigers | 48:53 |
| 11. | davidb69 | 4,599 | Episode 80 PS2 MLB 06 the show Road to MLB the show 20 | 47:52 |
| 12. | Larry Miller | 4,002 | MLB 2006 Gameplay - PS2 | 18:15 |
| 13. | Pichu London Sports | 3,742 | MLB 06 The Show [PSP] | Sports Game Ballparks 🏟 ⚾️ | 1:02:33 |
| 14. | rocksoldier97 | 3,702 | PS2 Gaming! Episode 2599: MLB '06: The Show | 44:02 |
| 15. | 30-30 Club - Baseball Video Game Encyclopedia | 3,318 | MLB 06 The Show (PSP) - CPU vs. CPU Gameplay | 1:29:59 |
| 16. | Gaming Off The Grid | 2,584 | PS2 Jam Pack Volume 15 | DEMO Disc Vault | 15:23 |
| 17. | The Campy Company | 1,640 | Sports Games Reviews Ep. 26: MLB 06: The Show (PS2) | 50:55 |
| 18. | DarkShadowX25 | 1,315 | Jampack Demo Disc Volume 12 Part 6 - MLB 2006 | 26:04 |
| 19. | Throwback Gaming Clips | 1,220 | Bobby Abreu owns me | MLB 06: The Show (PS2) | 0:00 |
| 20. | 259 Sports | 1,017 | MLB 06 THE SHOW King Of The Diamond Showcase Crimson VS Cobalt | 1:37:08 |
| 21. | GamePlayStation | 866 | MLB 06: The Show -- Gameplay (PS2) | 30:29 |
| 22. | HPC OTI | 647 | MLB 06 The Show RTTS Part 51 PPSSPP | 0:52 |
| 23. | NickWagerGames | 363 | I PLAYED THE FIRST EVER MLB THE SHOW! (MLB 06 The Show) | 9:22 |
| 24. | Officer Darkfox | 332 | MLB 06 how to get MONEY (works in every MLB game ever made) | 0:00 |
| 25. | Kasabe | 290 | Welcome to The Show (A Retrospective on MLB 06) - A History of The Show, Episode 4 | 12:06 |
| 26. | Seannosaurus Rex | 260 | Seattle Mariners @ Boston Red Sox | Spring Training [#3] | MLB 06: The Show Gameplay | 1:13:21 |
| 27. | TBwellss_Retro_Gaming | 256 | MLB PS2 ( 720 HD ) | 1:14:59 |
| 28. | Null 48 | 247 | MLB 06 The Show Android - PSP Emulator PPSSPP - Gameplay 2022 | 9:07 |
| 29. | notyourusualZero | 148 | Let's Mumble Over OPM Issue 105 Part 3 | 32:12 |
| 30. | Stream's VODs | 97 | MLB '06: The Show - I Am Not Good At Baseball Games | PS2 Gauntlet #2 (Twitch VOD) | 1:14:09 |
| 31. | Jordan2002's Corner of Nostalgia | 87 | "MLB 06: The Show" for Sony PlayStation 2 Online TV commercial (2006) | 0:00 |
| 32. | d4rkjust1c3 | 75 | MLB The Show 06 - Baltimore Orioles vs. Kansas City Royals - PSP - 1080P | 1:25:27 |
| 33. | Doan's PlayStation Reviews | 63 | Ep. 15 - MLB 06: The Show | 3:43 |
| 34. | Peter Skerritt | 49 | Unsealed: Welcome to The Show | 12:00 |
| 35. | Roll Tide | 48 | Career Birmingham Barons Part 16 | 20:10 |
| 36. | trouvaille | 42 | Transfer - Smoke of the Crowd (MLB 06 The Show OST) [Slowed + Reverb] | 0:00 |
| 37. | Rodriguez_0829 | 28 | MLB PSP Pirates vs Padres | 0:00 |
| 38. | Nik7mik | 10 | Striking out in MLB 06 The Show for Xbox 360! #gaming #baseball #sportsgaming | 0:00 |
| 39. | Luminous | 10 | One Off #266 MLB 06: The Show | 0:00 |
| 40. | JakesterIX | 1 | MLB 06: The Show JakesterIX Gameplay | 0:00 |
| 41. | VideoGameX | 1 | MLB 06: The Show | VideoGameX | 10:01 |
