| 1. |  EnterElysium | OPUS MAGNUM | HANGOVER CURE #01 Amazing Alchemist Game - Let's Play / Gameplay | 128 | Let's Play |
| 2. | EnterElysium | OPUS MAGNUM Amazing Alchemist Game - Let's Look / Gameplay | 109 | Let's Play |
| 3. |  KatherineOfSky | Opus Magnum Ep 1: IMPERIAL UNIVERSITY - Programming/Logic - First Look - Let's Play (Early Access) | 81 | Let's Play |
| 4. | EnterElysium | OPUS MAGNUM | MACHINE OIL #02 Amazing Alchemist Game - Let's Play / Gameplay | 39 | Let's Play |
| 5. | Wanderbots | Let's Play Opus Magnum - PC Gameplay Part 1 - Mindbender | 35 | Let's Play |
| 6. | EnterElysium | OPUS MAGNUM | STAMINA POTION #03 Amazing Alchemist Game - Let's Play / Gameplay | 28 | Let's Play |
| 7. | Wanderbots | Let's Play Opus Magnum - PC Gameplay Part 6 - One Armed Wonder | 15 | Let's Play |
| 8. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #67 | LAMPLIGHT GAS | 9 | Let's Play |
| 9. | Stuff+ | Opus Magnum - Purification Programming Puzzle - Let's Play / Gameplay / Beverage | 8 | Let's Play |
| 10. | Stuff+ | How Does Alchemy Work Again? | Opus Magnum - Let's Play / Gameplay | 8 | Let's Play |
| 11. | Deer Darling | Collision Course - Opus Magnum - Let's Play - Part 7 | 8 | Let's Play |
| 12. | Wanderbots | Let's Play Opus Magnum - PC Gameplay Part 7 - The Fall Of House Van Tassen | 7 | Let's Play |
| 13. | Deer Darling | Health & Stamina - Opus Magnum - Let's Play - Part 3 | 6 | Let's Play |
| 14. | Deer Darling | Magnum Opus? - Opus Magnum - Let's Play - Part 18 | 6 | Let's Play |
| 15. | Deer Darling | Crystal Timing - Opus Magnum - Let's Play - Part 15 | 6 | Let's Play |
| 16. | Deer Darling | Brain Lag - Opus Magnum - Let's Play - Part 11 | 6 | Let's Play |
| 17. | Deer Darling | Crown Jewels - Opus Magnum - Let's Play - Part 13 | 5 | Let's Play |
| 18. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #69 | WELDING THERMITE | 5 | Let's Play |
| 19. | Deer Darling | Abrasive Vapor - Opus Magnum - Let's Play - Part 23 | 5 | Let's Play |
| 20. | Deer Darling | Alchemical Starts - Opus Magnum - Let's Play - Part 1 | 4 | Let's Play |
| 21. | Deer Darling | Uncharted Territories - Opus Magnum - Let's Play - Part 8 | 4 | Let's Play |
| 22. | Deer Darling | Rumblings of War - Opus Magnum - Let's Play - Part 4 | 4 | Let's Play |
| 23. | Deer Darling | New Idea - Opus Magnum - Let's Play - Part 16 | 4 | Let's Play |
| 24. | Deer Darling | Suspicious Viscious Sludge - Opus Magnum - Let's Play - Part 20 | 3 | Let's Play |
| 25. | Deer Darling | Long Chains & Hurt Brains - Opus Magnum - Let's Play - Part 9 | 3 | Let's Play |
| 26. | Deer Darling | Let's See the Fireworks! - Opus Magnum - Let's Play - Part 25 | 3 | Let's Play |
| 27. | Deer Darling | Fontenelle's Observations & Sigmar's Garden - Opus Magnum - Let's Play - Part 19 | 3 | Let's Play |
| 28. | Deer Darling | Live in the Shadows - Opus Magnum - Let's Play - Part 6 | 3 | Let's Play |
| 29. | Deer Darling | Fast Forward - Opus Magnum - Let's Play - Part 14 | 3 | Let's Play |
| 30. | Deer Darling | Eyedrops of Revelation - Opus Magnum - Let's Play - Part 24 | 3 | Let's Play |
| 31. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #74 | ALCHEMICAL SLAG | 3 | Let's Play |
| 32. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #83 | EMBALMING FLUID | 3 | Let's Play |
| 33. | Wanderbots | Let's Play Opus Magnum - PC Gameplay Part 15 - Chain Link | 3 | Let's Play |
| 34. | Deer Darling | Beauty in Simplicity - Opus Magnum - Let's Play - Part 2 | 3 | Let's Play |
| 35. | Deer Darling | In a Bind - Opus Magnum - Let's Play - Part 10 | 3 | Let's Play |
| 36. | Deer Darling | "Courage Potion" - Opus Magnum - Let's Play - Part 5 | 3 | Let's Play |
| 37. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #71 | REACTIVE GOLD | 3 | Let's Play |
| 38. | Deer Darling | Model Alchemist - Opus Magnum - Let's Play - Part 26 | 2 | Let's Play |
| 39. |  Hog Play | 08 Alcohol Seperation | 2 | Let's Play |
| 40. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #64 | TONIC OF HYDRATION | 2 | Let's Play |
| 41. | Wanderbots | Let's Play Opus Magnum - PC Gameplay Part 16 - Topsy Turvy | 2 | Let's Play |
| 42. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #66 | LUSTRE | 2 | Let's Play |
| 43. | Deer Darling | Alchemical Amaro - Opus Magnum - Let's Play - Part 22 | 2 | Let's Play |
| 44. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #63 | BLOOD STANCHING POWDER | 2 | Let's Play |
| 45. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #62 | SUTURE THREAD | 2 | Let's Play |
| 46. | Gaming With Tor | Opus Magnum | I think we can beat this today | Part 4 | 2 | Let's Play |
| 47. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #85 | SYNTHETIC MALACHITE (CENTERED PRODUCT CHALLENGE) | 2 | Let's Play |
| 48. | That Design Feel | Let's Play Opus Magnum | Part 1 | Chapters I & II | Nostalgic Puzzle Gameplay | 2 | Let's Play |
| 49. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #68 | CONDUCTIVE ENAMEL & LAMPLIGHT GAS REVISITED | 2 | Let's Play |
| 50. | Gaming With Tor | Playing this puzzle game on mah bday | Opus Magnum | Part 3 | 2 | Let's Play |
| 51. | Deer Darling | Pure Gold - Opus Magnum - Let's Play - Part 12 | 2 | Let's Play |
| 52. | Deer Darling | Fragrant Poisons - Opus Magnum - Let's Play - Part 21 | 2 | Let's Play |
| 53. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #81 | VANISHING MATERIAL | 2 | Let's Play |
| 54. | That Design Feel | Let's Play Opus Magnum | Part 4 | Chapter V | Nostalgic Puzzle Gameplay | 2 | Let's Play |
| 55. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #82 | SYNTHETIC MALACHITE | 2 | Let's Play |
| 56. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #65 | HEXSTABILIZED SALT | 2 | Let's Play |
| 57. | Game Fanatic | Opus Magnum - Helping With The War Effort | 1 | Let's Play |
| 58. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #70 | VAN BERLO'S PIVOTS | 1 | Let's Play |
| 59. | Jerp | Jerp plays Opus Magnum pt.3 - Let's add a dash of Thievery (2021-01-24) | 1 | Let's Play |
| 60. |  Keywii Plays | Keywii Plays Opus Magnum (43) | 1 | Let's Play |
| 61. | The Proximity | Opus Magnum Adventure || E06 || Airship Fuel [Let's Play] | 1 | Let's Play |
| 62. | GQSmoos | Let's Play OPUS MAGNUM by Zachtronics #72 | ASSASSIN'S FILAMENT | 1 | Let's Play |
