| 1. |  jacksepticeye | MY ASS IS GOING VIRAL | Plague Inc. Evolved #1 | 41,174 | |
| 2. |  SSundee | DON'T CATCH THE UGLY VIRUS! (Plague Inc) | 32,962 | |
| 3. | Doctor Mike | Doctor Plays Plague Inc. | The Ultimate Bacteria! | Wednesday Checkup | 30,292 | Let's Play |
| 4. | jacksepticeye | DEEZ NUTS ARE INFECTIOUS | Plague Inc. Evolved #3 | 27,290 | |
| 5. | jacksepticeye | SLEEP IS FOR THE WEAK | Plague Inc. Evolved #5 | 25,612 | |
| 6. | RTGame | Destroying All Of Humanity in The Worst Possible Ways in Plague Inc. | 20,276 | |
| 7. | jacksepticeye | STUPIDITY IS SPREADING | Plague Inc. Evolved #2 | 20,033 | |
| 8. | jacksepticeye | SEPTIC SPREADS | Plague Inc. Evolved #4 | 16,289 | |
| 9. |  Enes Batur S | YOUTUBE'DAN GELEN MUHTEŞEM HEDİYE | 16,289 | |
| 10. | SSundee | You have the Donald Trump Virus! (Plague Inc.) | 15,452 | |
| 11. | jacksepticeye | ALL YOU NEED IS LOVE | Plague Inc. Evolved #8 | 13,641 | |
| 12. |  BeastBoyShub | Spreading Positivity in the World ❤️ | 13,424 | |
| 13. | jacksepticeye | OPEN WIDE | Plague Inc. Evolved #13 | 12,840 | |
| 14. | jacksepticeye | THE SEPTIC VIRUS | Plague Inc. Evolved #11 | 12,769 | |
| 15. | SSundee | Plague Inc | Infect the World with The Saimian Virus | 12,650 | |
| 16. | jacksepticeye | ZOMBIELAND | Plague Inc. Evolved #7 | 12,420 | |
| 17. | SSundee | Plague Inc | Infect the World with "Your Mom" Parasite | 12,174 | |
| 18. | Enes Batur S | BÜTÜN İNSANLARI ÖLDÜRMEK | 11,940 | |
| 19. | jacksepticeye | ATTACK OF THE FAN GIRLS | Plague Inc. Evolved #14 | 11,728 | |
| 20. | SSundee | Plague Inc | Infect the World with Bieber Fever Fungus | 11,292 | |
| 21. | jacksepticeye | YOUR MOM'S ASS IS LETHAL | Plague Inc. Evolved #6 | 11,173 | |
| 22. |  Saudi Gamer - سعودي جيمر | شركة الطاعون : فيروس كورونا | 10,719 | |
| 23. | jacksepticeye | DOUBLE DISEASE! | Plague Inc. Evolved Multiplayer #1 | 10,396 | |
| 24. | jacksepticeye | POPCORN HEADS | Plague Inc. Evolved #17 | 10,010 | |
| 25. | SSundee | Plague Inc Multiplayer | THE DONALD TRUMP | 9,881 | |
| 26. | BeastBoyShub | Corona Virus is On Top of Our Heads..... | 9,681 | |
| 27. | jacksepticeye | SOCIAL MEDIA WILL KILL US ALL | Plague Inc. Evolved #15 | 9,654 | |
| 28. | jacksepticeye | SPREADING THE SICKNESS | Epidemic | 9,356 | |
| 29. | Thinknoodles | This Game GOT BANNED In China! | Plague Inc | Fan Choice FRIGHTday | 9,255 | |
| 30. |  TazerCraft | ESTAMOS DOENTES será esse o FIM DO CANAL! 🤢 | 9,179 | |
| 31. | Jazzghost | CRIEI UM VÍRUS QUE VAI DIZIMAR A HUMANIDADE! - Plague Inc. | 9,057 | |
| 32. | SSundee | Plague Inc | Infect the World with the Prion "McDonalds" | 8,821 | |
| 33. | jacksepticeye | IT'S GETTING NIPPY | Plague Inc. Evolved #9 | 8,608 | |
| 34. | jacksepticeye | FREE FACE HUGS | Plague Inc. Evolved #12 | 8,567 | |
| 35. | Pravus | Plague Inc. Evolved - Shadow Plague Walkthrough (Mega Brutal) | 8,224 | Walkthrough |
| 36. | jacksepticeye | THERE'S A MONSTER INSIDE ME | Plague Inc. Evolved #16 | 7,715 | |
| 37. | jacksepticeye | I DESTROYED THE WORLD | Plague Inc. | 7,353 | |
| 38. | jacksepticeye | TRUST ME, I'M A DOCTOR | Bio Inc. Redemption #4 | 7,116 | |
| 39. | SSundee | Plague Inc Multiplayer | EVOLVE THE UGLY!! | 6,349 | |
| 40. | jacksepticeye | PREPARE FOR MONKEE BUTTS | Plague Inc. Evolved #10 | 6,008 | |
| 41. |  LazarBeam | DONT WATCH THIS WITH YOUR PARENTS! (Plague Inc) | 5,997 | |
| 42. | jacksepticeye | FIGHT FOR VIRALITY | Plague Inc. Evolved Multiplayer #2 | 5,883 | |
| 43. |  AdamChromeE | Greenland in Plague Inc. are like: | 5,714 | |
| 44. | jacksepticeye | DOWN WITH THE SICKNESS | Bio Inc. Redemption #2 | 5,531 | |
| 45. | jacksepticeye | SICKNESS TRUMPS ALL | Bio Inc. Redemption #3 | 5,300 | |
| 46. | GameGrumps | Plague Inc. - Steam Train | 4,819 | |
| 47. |  AradirOff | infectando a todo el mundo 🌍😈 | 4,774 | |
| 48. | Thinknoodles | I CURED COVID AND SAVED THE WORLD! | Plague Inc | 4,769 | |
| 49. | ParashockX | If I infect my country, I sing the national anthem - Plague inc. | 4,760 | |
| 50. |  Wankil Studio - Laink et Terracid | SIMULATION DU CORONAVIRUS DANS LE MONDE (Plague Inc) | 4,488 | |
| 51. |  The Spiffing Brit | Plague Inc Is A Perfectly Balanced Game With No Exploits - Unlock All Genes Instantly | 4,443 | |
| 52. | TazerCraft | DESTRUÍMOS O PLANETA! - PLAGUE INC. | 4,336 | |
| 53. |  Haman | Plague inc || اللعبة خلتني أقتل كل العرب 😱!! (( أنا آسف اذا دولتك منهم 😭)) محاكي المرض!! | 4,211 | |
| 54. | ELDED | EL CULONAVIRUS ES MUY PELIGROSO :O | 4,167 | |
| 55. | ParashockX | If Greenland gets infected, the video ends - Plague Inc. | 4,105 | |
| 56. |  laserluca | Mein CORONAVIRUS 😷😱 | 4,041 | |
| 57. | AradirOff | me volví un huracán 😎🌪️ | 3,959 | |
| 58. | Jazzghost | AGORA SIM! CRIEI UM VIRUS QUE MATOU TODA A HUMANIDADE! - Plague Inc. | 3,952 | |
| 59. | Baturay Anar | Bu virüs 7,124,543,962 insanı öldürdü.. | 3,900 | |
| 60. | EstubeGaming | فيروس كورونا | Plague Inc. Evolved !! 😲☢ | 3,764 | |
| 61. | Mitten Squad | Can You Beat Plague Inc Without Spending Any DNA Points? | 3,665 | |
| 62. | Jazzghost | EU ENGANEI 7 BILHÕES DE PESSOAS COM UMA FAKE NEWS! - Plague Inc. | 3,426 | |
| 63. | 김성회의 G식백과 | [전염병 주식회사] 게임이 예견한 코로나 판데믹 | 3,400 | |
| 64. |  FROST | КОРОНАВИРУС из КИТАЯ ПОБЕЖДАЕТ ЛЮДЕЙ | 3,325 | |
| 65. | JinBop | Plague Inc: JINBOP SPREADS LIKE A VIRUS!! | 3,298 | |
| 66. | The Frustrated Gamer | I Created The Most DEADLY VIRUS! | Plague Inc | 3,291 | |
| 67. | Haman | نشرت مرض كورونا عند العرب 😱💉 !! (( نهاية العالم 🌍 )) !! || Plague inc 2020 | 3,148 | |
| 68. | Zangado | Plague Inc.Evolved : Vale ou não a pena jogar | 2,950 | |
| 69. |  MattShea | So THIS is the #1 Mobile Game Now... (Plague Inc.) | 2,849 | |
| 70. |  Doctor Vic | DOCTOR REAL JUEGA "PLAGUE INC" | GAMEPLAY BRUT4L | DOCTOR VIC | 2,697 | |
| 71. | Jazzghost | SALVEI O MUNDO CRIANDO UMA CURA PRA PANDEMIA! - Plague Inc. | 2,686 | |
| 72. | Hitesh KS : Hindi Gaming | BIMARI Simulator 😂 | Funny Moments | Hitesh KS | 2,573 | |
| 73. | Les Pizza Guys | LE VIRUS LE PLUS MEURTRIER ! - Plague Inc #2 | 2,482 | |
| 74. | TrippyPepper | So I Hacked Plague Inc & infected billions of people in minutes... (MAX DISEASE) | 2,453 | |
| 75. |  Lasse Vestergaard | Bubber DRÆBER HELE VERDENEN! Plague Inc (Afsnit 1) | 2,432 | |
| 76. | HybridPanda | LET'S KILL EVERYONE!! Plague Inc. Evolved | 2,414 | |
| 77. | Saiman Says | TIKTOK vs Coronavirus | Plague Inc. (Saiman Plays) | 2,338 | Let's Play |
| 78. | Pravus | Plague Inc: Custom Scenarios - SPC-001: When Day Breaks | 2,325 | |
| 79. | EazySpeezy | I got the world record for Plague Inc | 2,300 | |
| 80. |  TheBrainDit | Plague Inc. - ВИРУС ОЛЕГА БРЕЙНА | 2,297 | |
| 81. |  Folagor03 | ¿NO SABERSE LA TABLA DE TIPOS ACABARÁ CON EL PLANETA? | Plague Inc #2 | 2,275 | |
| 82. | ViteC ► Play | КОРОНАВИРУС ► Plague Inc. Evolved |34| | 2,270 | |
| 83. | HybridPanda | Damn it Canada! - Plague Inc. Evolved with Panda #6 | 2,200 | |
| 84. | レトルト | 『危険なウイルス』を作って人類を滅亡させてみた【Plague Inc】 | 2,166 | |
| 85. | Pravus | Plague Inc. Evolved - Simian Flu Walkthrough (Mega Brutal) | 2,160 | Walkthrough |
| 86. | HybridPanda | We Need Master Chief! - Plague Inc. Evolved #5 | 2,137 | |
| 87. | TheBrainDit | Plague Inc. - ВИРУС ПО СЕТИ (Обзор) | 1,994 | |
| 88. | 겜브링 GGAM BRING | 세상 모든 사람들은 '브링뽕' 바이러스에 취하게 된다!! - 전염병 주식회사(Plague Inc) - 겜브링(GGAMBRING) | 1,977 | |
| 89. | Pravus | Plague Inc. Custom Scenarios - Rise of the Catgirls | 1,947 | |
| 90. | Alvaro845 Clash | La clave es matar a los canadienses primero | Plague Inc | Juegos para iOS & Android | 1,894 | |
| 91. | Folagor03 | LOS HATERS DESTRUIRÁN ABSOLUTAMENTE TODO | Plague Inc #3 | 1,873 | |
| 92. | TobyGames | Let's Play INFECTION (Plague Inc.) | 1,854 | Let's Play |
| 93. | HybridPanda | Cthulu Rises! - Plague Inc. Evolved #4 | 1,840 | |
| 94. | Pravus | Plague Inc. Custom Scenarios - Anti-Plague | 1,836 | |
| 95. |  Robbaz | Plague Inc. Evolved - Eradicate Life on Earth | 1,830 | |
| 96. | Pravus | Plague Inc. Custom Scenarios - Rise of the Xenomorphs | 1,829 | |
| 97. | Pravus | Plague Inc. Custom Scenarios - Trump's Awakening | 1,818 | |
| 98. | HybridPanda | Panda-Flu Arrives! - Plague Inc. Evolved #2 | 1,806 | |
| 99. | 겜브링 GGAM BRING | 뇌 기생충 감염주의!! 브링뽕이 세상을 조종한다?!! - 전염병 주식회사(Plague Inc) - 겜브링(GGAMBRING) | 1,805 | |
| 100. | aLexBY11 | ACABA CON ELLOS!!! (Plague Inc) Parte 2 | 1,788 | |
