| 1. |  OfficialNerdCubed | 884,465 | Nerd³ The Alpha Detective - Plague Inc: Evolved | 28:19 |
| 2. | caramida9 | 71,302 | X-NANO VIRUS! Let's play: Plague Inc. Evolved Custom Scenario | 14:33 |
| 3. | Forsen Plays | 21,628 | Forsen Plays Plague Inc: Evolved Versus Streamsnipers | 1:14:56 |
| 4. | The Wandering Inn | 4,022 | Santa's Little Helper - A Close Call (Plague Inc Evolved) | 22:30 |
| 5. | Stuff+ | 3,918 | Beverage + Plague Inc: Evolved [Early Access] #5 | 26:45 |
| 6. | Feniks | 2,856 | Plague Inc Evolved - POSSESSION - Workshop Custom Scenarios Let's play | 12:53 |
| 7. | Jennyverse | 1,407 | "PUT IT INTO DOGS" - Let's Play Plague Inc: Evolved (Badly) #4 | 21:22 |
| 8. | Devilish | 1,380 | Plague Inc Evolved - Part 8 - Teenage Pregnancy - Devilish Plays | 12:38 |
| 9. | JustaSlav_ | 1,361 | Plague Inc: Evolved- Complete Smallpox Achievement | 3:31 |
| 10. | TheGamakazi | 1,111 | Let's Play Plague Inc - Evolved: Part 3 Love Makes You Do Crazy Things | 13:22 |
| 11. | The Geek Cupboard | 1,006 | Killing Humanity with... Tea Addiction! | Plague Inc: Evolved | 54:21 |
| 12. | AnthWolf | 513 | Let's Play Plague Inc: Evolved Part 3 (Bacteria) | 14:34 |
| 13. | ScalperHero | 242 | Trust - Plague Inc Evolved - Part 3 (Fungus) | 12:47 |
| 14. | Slayer9009 | 143 | Plague Inc Evolved Bacteria Gameplay - First time we're doing this, so let's go take over the world! | 15:05 |
| 15. | Second Level Gaming | 111 | Let's Play Live: Plague Inc Evolved - Coronavirus Simulator | 44:41 |
| 16. | Mrcheekymonkey1996 | 77 | Lets Play: Plague Inc Evolved as a VIRUS ON "Brutal" (face cam) | 15:34 |
| 17. | Μr eVо | 64 | Mr eVo Plays Plague Inc Evolved | LOGAN PAUL DISEASE | 18:46 |
| 18. | David William Beck (Wartorious) | 54 | Let's Play Plague Inc Evolved | World-Conquering Strategy Game 🌍🔥 | 24:51 |
| 19. | Jimbo Spike | 47 | Let's Play Plague Inc Evolved (ALPHA) - Jimbo-1 | 35:02 |
| 20. | YixelGaming | 46 | Let's Play Plague Inc: Evolved | 27:24 |
| 21. | iGame | 31 | *Live Play* - Plague Inc: Evolved Playthrough | 43:11 |
| 22. | Chris Dyer | 30 | Plague Inc fungus let's play | 12:36 |
| 23. | PalicoPadge | 30 | Padge Plays! YOLO Edition: Plague Inc: Evolved (2016 - Ndemic Creations) Creating A Zombie Plague! | 33:40 |
| 24. | Island of Rob Gaming | 13 | Plague Inc Evolved First Playthrough E03 I'm a Virus now 2019 06 19 | 2:16:39 |
| 25. | Khazaboom | 10 | ALL HAIL JIM | Plague Inc Evolved #4 | 15:56 |
| 26. | GamingRack | 5 | Taking Over The World | Plague Inc: Evolved | 24:19 |
| 27. | Jason Silverain | 5 | Silverain Plays: Plague Inc: Evolved [Mod: C0vid] | 10:26 |
