| 1. |  GamingMemoirs | Let's Play Prototype 2 Part 19 (Butt Kicking Bio Bomb) | 2,323 | Let's Play |
| 2. | GamingMemoirs | Let's Play Prototype 2 Part 2 (Hunting) | 1,798 | Let's Play |
| 3. | GamingMemoirs | Let's Play Prototype 2 Part 29 (Final Boss) | 1,302 | Let's Play |
| 4. | Kevin | Prototype 2 Walkthrough Part 35 - Helping Black Watch | 929 | Let's Play |
| 5. | Hypercore Ripper | Miniplays - Episode 17 - Prototype 2 w/ Hypercore Ripper | 777 | Let's Play |
| 6. | GamingMemoirs | Let's Play Prototype 2 Part 15 (Swords) | 728 | Let's Play |
| 7. | GamingMemoirs | Let's Play Prototype 2 Part 5 (Hive) | 533 | Let's Play |
| 8. | GamingMemoirs | Let's Play Prototype 2 Part 1 (prolouge) | 408 | Let's Play |
| 9. | GamingMemoirs | Let's Play Prototype 2 Part 3 (Claws) | 399 | Let's Play |
| 10. | GamingMemoirs | Let's Play Prototype 2 Part 7 (Hydra Tendrils) | 344 | Let's Play |
| 11. | GamingMemoirs | Let's Play Prototype 2 Part 4 (Infiltration) | 248 | Let's Play |
| 12. | GamingMemoirs | Let's Play Prototype 2 Part 18 (Barrel Football) | 234 | Let's Play |
| 13. | GamingMemoirs | Let's Play Prototype 2 Part 6 (Brain Drain) | 216 | Let's Play |
| 14. | GamingMemoirs | Let's Play Prototype 2 Part 11 (Super Soldiers) | 195 | Let's Play |
| 15. | GamingMemoirs | Let's Play Prototype 2 Part 23 (Goliath) | 189 | Let's Play |
| 16. | GamingMemoirs | Let's Play Prototype 2 Part 16 (Grand Theft Prototype) | 168 | Let's Play |
| 17. | GamingMemoirs | Let's Play Prototype 2 Part 25 (New Friends) | 158 | Let's Play |
| 18. | GamingMemoirs | Let's Play Prototype 2 Part 20 (Alpha Wolf) | 147 | Let's Play |
| 19. | GamingMemoirs | Let's Play Prototype 2 Part 12 (Mutant Boss) | 139 | Let's Play |
| 20. | GamingMemoirs | Let's Play Prototype 2 Part 8 (It's a trap) | 138 | Let's Play |
| 21. | Orylen | Let's Play Prototype 03: Family Ties | 138 | Let's Play |
| 22. | GamingMemoirs | Let's Play Prototype 2 Part 13 (Armored Tank) | 127 | Let's Play |
| 23. | Orylen | [E] Let's Play Prototype 03: Before A New Order | 117 | Let's Play |
| 24. | GamingMemoirs | Let's Play Prototype 2 Part 17 (New Allies) | 115 | Let's Play |
| 25. | GamingMemoirs | Let's Play Prototype 2 Part 26 (Whip Fist) | 111 | Let's Play |
| 26. | GamingMemoirs | Let's Play Prototype 2 Part 22 (Rewind) | 93 | Let's Play |
| 27. | GamingMemoirs | Let's Play Prototype 2 Part 10 (Salvation) | 91 | Let's Play |
| 28. | GamingMemoirs | Let's Play Prototype 2 Part 24 (Red Zone) | 90 | Let's Play |
| 29. | GamingMemoirs | Let's Play Prototype 2 Part 27 (Becoming Human Again) | 81 | Let's Play |
| 30. | GamingMemoirs | Let's Play Prototype 2 Part 14 (Sneaking) | 75 | Let's Play |
| 31. | GamingMemoirs | Let's Play Prototype 2 Part 28 (Thermobaric) | 74 | Let's Play |
| 32. | Kush Coffee N Games | Lets Play Prototype 2 ep.1 Looking A Gift Virus In The Mouth | 68 | Let's Play |
| 33. | Kush Coffee N Games | Lets Play Prototype 2 ep.6 Special Mutations | 58 | Let's Play |
| 34. | Kush Coffee N Games | Lets Play Prototype 2 ep.3 New Zone, New Mutations | 55 | Let's Play |
| 35. | Kush Coffee N Games | Lets Play Prototype 2 ep.5 Entering The Red Zone | 54 | Let's Play |
| 36. | Kush Coffee N Games | Lets Play Prototype 2 ep.7 The Last Blacknet Mission | 53 | Let's Play |
| 37. | Kush Coffee N Games | Lets Play Prototype 2 ep.4 Blackwatch Butcher Shop | 35 | Let's Play |
| 38. | Kush Coffee N Games | Lets Play Prototype 2 ep.2 Making Some Soldier Sandwiches, Om Nom Nom | 34 | Let's Play |
| 39. | Renzolian Plays Games | Renzo Plays [PROTOTYPE 2] | 19 | Let's Play |
| 40. | Kush Coffee N Games | Lets Play Prototype 2 ep.8 Murdering Our Maker | 18 | Let's Play |
| 41. | Barbara Schnarr | [Prototype 2]: Alpha Wolf | 14 | Let's Play |
