| 1. |  A3D's Lets Plays | 86,033 | LPwA3D Classics: Quake 4 Stroggification | 18:16 |
| 2. | Preturnax | 82,197 | Quake IV Soundtrack - Hangar Shotgun | 1:14 |
| 3. | Corpseflesh | 52,489 | Quake 4 - Any% speedrun in 1:45:27 (time without loads) | 1:50:35 |
| 4. | TheRasaf | 51,709 | Let´s play Quake 4 Deutsch Kommentiert part 12 Finale | 29:14 |
| 5. | ComputerBase | 43,345 | Quake 4: Raytraced | 1:07 |
| 6. | GermanPeter | 9,507 | The Quirks of German Quake 4 | 12:10 |
| 7. | Eagl2009 | 8,525 | Эти Xbox 360 игры я жду на Xbox Series X/S после завершения сделки Microsoft / Activision Blizzard | 41:06 |
| 8. | r3un1on | 5,000 | Quake 4 - On Intel HD Graphics 4600 Test | 11:23 |
| 9. | MOUZ | 3,858 | mousesports - Faninterview with mouz|Cooller (Quake 4) | 5:36 |
| 10. | Papa Klaus (Daibola) | 2,872 | Quake 4 (uncut) ◾ German Longplay ◾ Part 3 von 3 ◾ [unkommentiert] ◾ 1440p@60Fps | 2:20:16 |
| 11. | The AndroidFerret | 2,795 | QUAKE IV for GZDoom and Zandronum #deltatouch | 0:15 |
| 12. | GamingTux | 2,679 | QUAKE 4 [#024] [Linux] - Home sweet Home [Let's Play] | 22:15 |
| 13. | UltrawideMasterrace | 2,400 | Quake 4 Stroggification | 3:36 |
| 14. | 123Actionful | 2,014 | Quake 4 (TEST - Heft 12/2005) | 9:25 |
| 15. | k1llsen | 1,958 | welcome back to Quake 4 /w k1llsen p2 | 37:19 |
| 16. | Saeva-Risus | 1,893 | The Stroggification 4 #shorts #stroggofication #quake #shooter #saevarisus | 0:00 |
| 17. | null | 1,774 | Quake 4 Gameplay | 3:31 |
| 18. | ScreenFire Germany | 1,596 | Ist Quake 4 wirklich der schlechteste Teil der Reihe? | Retro Donnerstag | 2:03:30 |
| 19. | Peacemaker zockt | 1,146 | #24 ● Ein Hoch auf Zerstörung (FINALE) ● Quake 4 [BLIND] [UNCUT] | 9:31 |
| 20. | TheNvgLet´sPlay | 805 | Shark Attack Deathmatch 2 Deutsch Part 8 Unbarmherziger SIEG Shark Attack Deathmatch 2 German | 15:39 |
| 21. | TwoLetsDo | 728 | Unboxing Quake 4 | 4:14 |
| 22. | Van FirleFranz | 697 | Quake 4 # 19 Hirnlos ballern bringt nichts BOSS FINALE Let's Play German, Deutsch | 22:28 |
| 23. | Ludophiles | 684 | Quake 4 Makron Final Boss Fight | 6:51 |
| 24. | Custom Longplay | 678 | Quake 4 - Map: #003 - Devil's Waitin' - [4K] - [100%] | 36:05 |
| 25. | PastGaming - Archiv | 654 | Games Aktuell 08/2005 - Trailer Quake 4 | 2:07 |
| 26. | MEM Productions | 610 | Mac Gaming Test - Quake 4 | 7:27 |
| 27. | JupiterFabrik | 454 | Quake 4 Uncut #25 Entscheidene Schlacht im Kern 🔚 Ende [German/Bayrisch] | 23:36 |
| 28. | LEVEL ONE | 443 | QUAKE 4 уже 18 лет а играется отлично - Прохождение на XBOX 360#1 | 37:31 |
| 29. | Blurksel | 443 | GS 2006/01 - Quake IV | Multiplayer-Duell | 5:28 |
| 30. | Patrick “El Blanco” Steuer | 334 | Quake 4: Final Boss-Battle / Ending & Credits | 19:25 |
| 31. | Buddys VR Lounge | 312 | VR Community Talk "System Shock Remake und Quake 4 in VR uvm !" | 2:42:42 |
| 32. | AcidicVoid ☆ アシヂクボイド | 265 | Quake 4 | Pt. 2 | Honig mit Kohlensäure | 2:37:28 |
| 33. | RetroChallengeGamer | 236 | Quake IV - Berserker Jump Scare - Old Let's Play Highlight | 0:00 |
| 34. | Saranya PLAY | 172 | [LIVE] PC l QUAKE 4 - สงครามอสูรกาย #1 [ENDE] | 5:03:07 |
| 35. | DasDonzi | 137 | 📢 Das Don macht Unfug! Live! | 58:12 |
| 36. | Ossel Pi | 129 | #012 Quake 4 Gameplay [EN/HD] - Finale | 50:25 |
| 37. | TapfererBus | 99 | Dummes Quake 4 spielen mit Discordleuten Part 3 Finale I Endlich ist der Scheiß geschafft | 3:04:48 |
| 38. | Drakim's VGM Channel | 88 | Drakim's VGM 331 - Quake 4 - Convoy | 2:07 |
| 39. | Nachbarnebenan | 87 | Quake⁴ - 07 Keine Pause | 12:31 |
| 40. | Ultra Wide Only | 86 | Quake 4 - 5120 x 1440 - Ultra Wide Gaming - 32:9 | 4:59 |
| 41. | Perudor | 76 | PROGRAMMVORSCHAU: 2017-Q4 | 19:08 |
| 42. | Dreadicuz | 76 | Die Nerven liegen blank | Quake#4 | Dreadicuz | 28:37 |
| 43. | ATNtheKOALA | 68 | Quake 4 | 4k MAXED OUT GAME PASS | Commentary Benchmark | RTX 4090 | i9 10850k | 3:06 |
| 44. | Robo n' Tux | 55 | Quake 4 [Linux] - Part 8/18 - Da kannste hier so dran Pinkeln ... | 26:48 |
| 45. | Conan Zockt | 44 | Quake 4 2021 002 | 9:42 |
| 46. | Play OST | 38 | Quake 4 OST Music Soundtrack | 34:21 |
| 47. | YesterPlay | 23 | #YesterPlay: Quake 4 (PC, Raven Software, 2005) | 26:28 |
| 48. | Sebtykum | 19 | Hitzig-Schwitziges Sci-Fi Horror egogeshoote mit Quake 4 / Kapitel III-IV | 6:10:18 |
| 49. | Shambler Games | 13 | Quake4_1080p_TEST | 3:46 |
| 50. | Aleric´s little Horror Show | 12 | Trash & Retro/ Shooterwochen bei Al´s / Quake IV | 14:17 |
| 51. | TheImp3rator | 10 | Quake 4 | 1:53:18 |
| 52. | Happy Gamer | 8 | Quake 4 #5 | 40:00 |
| 53. | Matschak | 6 | GRATIS Games! FREE Games | Epic Games & Prime Gaming | Matschak | 17.08.2023 | 8:20 |
| 54. | Mariano Paul ( Kanal 1 ) | 3 | Quake 4 | 1:15 |
| 55. | PC-Game Hunters | 2 | Quake 4 | 2:41 |
| 56. | Archiv von sem | 2 | Lass' spielen Quake 4 Lasst mich durch, ihr Monster! 1080p | 10:20 |
| 57. | NemoDiscovers | 1 | [18+] Discovery: Quake 4 | 45:54 |
