| 1. |  Ephemeral Rift | 831,680 | The First Annual Body Modification Signup at Arkham Sanitarium | ASMR | 29:33 |
| 2. | TheRPGMinx | 525,092 | THE CURE | Sanitarium | FINAL | 17:21 |
| 3. |  RawHand | 469,348 | ไอ้โรคจิต | 0:00 |
| 4. | PushingUpRoses | 415,238 | Top 11 Retro Adventure Games (That Are Not Sierra or LucasArts) PART 2! | 23:58 |
| 5. | NintendoComplete | 284,662 | Sanitarium (1998) PC Playthrough - NintendoComplete | 5:24:33 |
| 6. |  Dotemu | 256,625 | Sanitarium iOS / Android - Official Trailer | 0:30 |
| 7. | World of Longplays | 254,146 | PC Longplay [153] Sanitarium (Part 4 of 4) | 1:31:22 |
| 8. | Alex Hefner | 233,103 | You Gotta Be Kidding Me!! | METALLICA - "Welcome Home (Sanitarium)" | (REACTION) | 11:09 |
| 9. | Boulder Punch | 172,776 | A Point & Click Horror Fever Dream | Sanitarium | 0:00 |
| 10. | LGR | 133,986 | LGR - Sanitarium - PC Game Review | 4:32 |
| 11. | Adkit2 | 129,349 | Let's Play Sanitarium 45 (HD): Let's watch the credits roll! | 9:21 |
| 12. |  Kaftann | 128,916 | Zagrajmy w: Sanitarium #11 [Zakończenie] - Zaplątani [Gameplay PL / Let's Play PL] | 15:09 |
| 13. | DansGaming | 115,837 | Let's Play Sanitarium - Part 20 - Dansgaming HD Walkthrough PC | 36:23 |
| 14. |  TheRexenShow | 106,795 | L'OSCURO CONFRONTO! - [Pt.Finale] Sanitarium | 17:15 |
| 15. |  RagnarRox | 102,242 | Tokens of Memory: Sanitarium - Monsters of the Week - RagnarRox | 6:31 |
| 16. |  Dark Viper X | 82,679 | *NEW* UPDATED GOLD AND DIAMOND CAMOS | UPDATED SANITARIUM CABINET | PEEK KILL OPTION IN NEW VEHICLE | 8:11 |
| 17. | arhn.eu | 80,175 | Sanitarium [PC] - retro | Halloween 2014 | 7:15 |
| 18. |  Predrag Reviews | 79,993 | Sanitarium - HD (Full Walkthrough) | 5:21:40 |
| 19. | SEROTHS | 78,028 | Sweet Dreams (in)Sanitarium - Tu vas détester les enfants ! (pour changer) | 13:58 |
| 20. |  CJUGames | 75,670 | THE FINAL CHALLENGE - Let's Play Sanitarium Part 14 | 24:13 |
| 21. | AdventureGameFan8 | 70,543 | Sanitarium Walkthrough part 16 | 15:01 |
| 22. | Dilandau3000 | 68,240 | Let's Play Sanitarium - part 18 - The gauntlet | 45:15 |
| 23. | LethalFeline | 66,836 | Sanitarium w/ Grimith - 16 | 34:50 |
| 24. | OneShortEye | 65,729 | 3 Obscure Easter Eggs in Sanitarium | 7:25 |
| 25. | Huérfano Producciones | 60,744 | Sanitarium (Parte 04) The Circus of Fools | 23:43 |
| 26. | vicek83 - Świat przygodówek | 59,507 | Zagrajmy w Sanitarium cz. 37 - Ostatnia rozgrywka, zakończenie | 13:31 |
| 27. | ROJSON | 58,641 | SANITARIUM (Sentymentalnie przez gry #8) | 11:22 |
| 28. | VoidBurger Gaming | 57,485 | Let's Stream Sanitarium 16 | 26:42 |
| 29. | Vivian Cels | 56,518 | Sanitarium Шизариум sci-fi квест Прохождение part 06 | 8:21 |
| 30. | Toegoff | 50,306 | Let's Play Sanitarium - Part 19: More Village Wandering... | 17:11 |
| 31. |  StrawbellyLP | 47,430 | Sanitarium || 28 • Morgans letztes Spiel [FINAL] | 38:36 |
| 32. | NNiezapominajka | 45,914 | Let's Play: Sanitarium odc. 20: Ep. 9 - Ostatnia Rozgrywka - "Walka z sobą" | 42:46 |
| 33. | skythe1908 | 35,068 | Let's Play Sanitarium (Blind - Part 15) The End | 45:59 |
| 34. | JV - Jeux Vidéo | 31,952 | Le scandale qui a retiré des ventes ce chef-d'œuvre | 0:00 |
| 35. | Scarfulhu | 31,419 | Sanitarium | Hidden Depths | Scarfulhu | 46:58 |
| 36. |  Plouf et Pseudo | 29,656 | Que retenir de SANITARIUM? | 0:00 |
| 37. |  SoupCan Studios | 28,869 | [TF2 HORROR] Don't Join Team RED: SANITARIUM | 0:00 |
| 38. |  Dabfar | 27,364 | Обзор игры Sanitarium | 51:16 |
| 39. | Recenzje Horrorów | 27,231 | [PC] Sanitarium Recenzja gry | 7:19 |
| 40. | The Librarian | 25,958 | Sanitarium #5 - Buried Alive [FINAL] | 0:00 |
| 41. |  ZenBear | 24,892 | Let's Play: Sanitarium ► I AM MAX | #FINALE | 22:49 |
| 42. | NRGeek | 23,400 | Sanitarium - To bylo grane #18 (Stare Retro Gry) | 18:07 |
| 43. |  Oyunefendi | 22,124 | Oynayalım Bakalım: Sanitarium | Final Bölümü 10 | 2/2 | Türkçe Altyazılı Adventure Oyunu | 17:57 |
| 44. |  Virtuozila Game World | 21,598 | Sanitarium - Прохождение. Часть 13: Последняя игра Моргана. Финал | 0:00 |
| 45. | Disket Kutusu | 20,057 | KLASİK OYUNLAR VE RUHANİ VARİSLERİ | Sanitarium, Commandos ve Dahası... | 17:00 |
| 46. | Ryslaw | 19,616 | Sanitarium (4) - Czyżby KONIEC KOSZMARU? Gramy na żywo po polsku! | 0:00 |
| 47. | BlackEssence | 19,577 | BlackEssence Plays Sanitarium: Episode 15 "The Final Showdown!" | 13:40 |
| 48. |  LamNot | 17,834 | 【海外の名作】おすすめのホラーゲームランキングで必ず上位に入る名作『SANITARIUM』に挑戦！｜Sanitarium 実況｜#4 日本語同時通訳 | 1:28:15 |
| 49. | Day9TV | 17,143 | Mostly Walking - Sanitarium P2 | 1:48:03 |
| 50. | Старый Игровой Мир / Вспомнить Всё | 16,489 | Sanitarium (Шизариум) Полное прохождение. [игра 1998 года] | 7:25:22 |
| 51. | Locke Vincent | 15,939 | Sanitarium Review | 3:45 |
| 52. | C'est Quoi Ce Jeu ? | 15,754 | Sanitarium VF [Let's Play] épisode 21 - FINAL | 51:24 |
| 53. | RedSevenNine | 15,314 | Sanitarium Original Soundtrack (OST) | FULL | HD 1080p | 39:42 |
| 54. | ScummBR | 15,025 | Sanitarium (game) - Vídeos | 7:02 |
| 55. |  Retro Nation | 14,566 | Artefakt: Sanitarium + Datadisk: Isle of the Dead | 1:16:09 |
| 56. | Bensch | 13,870 | Sanitarium #023 - Psycho-Schleim-Schach (Finale) - Let's Play [german/deutsch] | 22:05 |
| 57. | Babbleplay | 12,805 | Sanitarium HD Babbleplay part 8 - Important Discoveries | 21:35 |
| 58. |  Daniel S | 12,634 | Metallica Producer: Making MASTER OF PUPPETS (Sanitarium, Battery, Disposable Heroes Damage Inc etc) | 13:08 |
| 59. | JK Bros | 12,527 | The SCARIEST HAUNTED Sanitarium!! SCARIEST APPARITION Caught by MINDSEED! JK BROS REACTION | 47:59 |
| 60. | Schnubbi | 12,102 | Sanitarium / Druidenzirkel | Ausgepackt | 5:30 |
| 61. | Sığınak Sakini | 11,555 | Let's Play : Sanitarium (Türkçe) - P12 - Manipülasyon | 39:01 |
| 62. | Squakenet | 11,385 | Sanitarium gameplay (PC Game, 1998) | 17:37 |
| 63. |  NyanGames Archive | 11,176 | [РЕТРО] Обзор игры Sanitarium (Шизариум) | 10:34 |
| 64. | Arcade Sushi | 10,985 | 10 Scariest Retro Games - The Rundown | 4:45 |
| 65. | Neco The Sergal | 10,513 | Puppet Combo's Sanitarium Massacre Found?! | Unfinished Worlds 2 | 23:25 |
| 66. | Chainbrain | 10,219 | METALLICA - WELCOME HOME (Sanitarium) in rocksmith 2014 | 0:39 |
| 67. | 4Player Network | 10,202 | Dance for me, Old Man! [Joseph - Sanitarium] | 0:31 |
| 68. | GameHorder | 10,087 | Let's Play - Sanitarium - 6 | 34:44 |
| 69. |  Laila Dyer | 10,012 | A Simple Craftsman | 1:19 |
| 70. | Diamond Snake | 9,218 | Sanitarium - Chapter 10, Morgan's last game | 9:33 |
| 71. | Gamezilla | 9,014 | Perły Lamusa #2: Sanitarium | 6:41 |
| 72. | LLOYD'S ASMR | 8,792 | ASMR - Arkham Sanitarium Origins (Featuring MasterCoul ASMR) | 22:52 |
| 73. | Rob Squad Reactions | 8,771 | WOW!| FIRST TIME HEARING Metallica - Welcome Home (Sanitarium) REACTION | 0:00 |
| 74. | The Music Recording Network | 8,546 | Metallica Welcome Home Sanitarium Live 1993 Basel Switzerland - Producer Reaction | 9:12 |
| 75. | BlizzBoyGames | 8,525 | DESCARGAR Sanitarium PC FULL ESPAÑOL PARA WINDOWS 7 GOG | 8:35 |
| 76. | Tarks Gauntlet | 8,261 | Exploring Sanitarium - Connecting The Dots & Story Explained - Tarks Gauntlet | 40:31 |
| 77. | Sooroosh Metalhead Piano | 7,977 | Metallica Welcome Home (Sanitarium) Piano Tutorial | 6:39 |
| 78. |  GRetroAndroid “TriforcePlay” | 7,170 | El Juego Mas Macabro Para Android (Sanitarium) | 1:02 |
| 79. | Canard PC | 7,060 | RETRO | Sanitarium avec L-F. Sébum | #6 | 2:00:38 |
| 80. | LavosCore | 7,043 | Zagrajmy w Sanitarium #21 Koniec szaleństwa. | 21:43 |
| 81. | Keylali Green | 7,004 | Прохождение Шизариум (Sanitarium) - серия 12 END. Финальное испытание | 41:34 |
| 82. | Andrea Pannocchia | 6,835 | Sanitarium (ITA) - [19/19] - [Cap.9 - 02/02] | 10:34 |
| 83. | Sanitarium.FM | 6,420 | Encased:- PC Early Access First Look with Darsch | 3:30 |
| 84. | СтудияПазл | 6,346 | ЭМУЛЯЦИЯ - Шизариум (Sanitarium) | 7:54 |
| 85. | WHAT IT DO DAVE | 6,333 | (Reaction) Metallica - Welcome Home (Sanitarium) | 15:42 |
| 86. | My Mystery Party | 6,297 | Murder at the Bloodstone Sanitarium - Murder Mystery Party Game by My Mystery Party | 1:30 |
| 87. | dospeh_play | 6,226 | Sanitarium - part 14: Финал | 33:10 |
| 88. |  Paz Boris | 6,151 | Sanitarium - La locura subconsciente | 6:01 |
| 89. | Das Dennis | 5,941 | Sanitarium (PC, 1998) - Review | 9:14 |
| 90. | Ящик Артефактов | 5,784 | Sanitarium [ИГРА, КОТОРАЯ МЕНЯ ИЗМЕНИЛА] feat. @RettaGames | 1:01:33 |
| 91. | KideRusha | 5,599 | Let's Play Sanitarium - Episode 29 [The End is Near] (Blind) | 14:24 |
| 92. | Lilia UNCUT | 5,418 | Let's Play SANITARIUM (Blind) #2 | 5:58:46 |
| 93. | Virtual Gaming Library - VGL | 5,312 | Sanitarium PC FULL GAME Longplay Gameplay Walkthrough Playthrough VGL | 5:50:17 |
| 94. | FiremanPC | 5,273 | Sanitarium - Sarah's Death | 1:42 |
| 95. | moviebob | 5,141 | SHUTTER ISLAND (2010) - Horror Retro-Review | 4:57 |
| 96. | Chainsaw Reacts | 5,123 | Metallica: Welcome Home (Sanitarium) Live (July 6, 2019) Reaction! | 14:11 |
| 97. |  El manso | 5,108 | Sanitarium | #9F | PC | Sub Español | Gameplay | Sin Comentarios | I5 8500 | GTX1070 | 31:08 |
| 98. | Chilluminati Podcast | 5,033 | Sanitarium - Worth Playing Today? - Judge Mathas | 18:20 |
| 99. |  Adventure Vault | 4,429 | Sanitarium | Complete Gameplay Walkthrough - Full Game | No Commentary | 5:22:33 |
| 100. | Eversor Fatalis | 4,271 | Let's Play Sanitarium: Part 19 - Belch Sparkles | 25:43 |
