| 1. |  Mind Pulp | Scooby-Doo but its a terrible PS2 game | 1,056 | Let's Play |
| 2. |  LongplayArchive | Longplay of Scooby-Doo! Mystery Mayhem [Old] | 475 | |
| 3. | DazzlingWalkthroughs | Scooby Doo Mystery Mayhem PS2 Walkthrough - Part 01 | 401 | Walkthrough |
| 4. |  Infinite Bits | The Most Underrated Scooby-doo Video Games | 216 | |
| 5. | DazzlingWalkthroughs | Scooby Doo Mystery Mayhem PS2 Walkthrough - Part 02 | 200 | Walkthrough |
| 6. | World of Longplays | Game Boy Advance Longplay [005] Scooby-Doo: Mystery Mayhem | 162 | |
| 7. | John GodGames | Scooby Doo!: Mystery Mayhem - Gameplay Xbox (Xbox Classic) | 158 | |
| 8. | ★WishingTikal★ | Scooby-Doo! Mystery Mayhem All Bosses | Boss Fights (PS2, Gamecube, XBOX) | 143 | |
| 9. |  Geração Power Up | Caçando Fantasmas! - Scooby-Doo: Mystery Mayhem #01 (PS2) | 139 | |
| 10. | ★WishingTikal★ | Scooby-Doo! Mystery Mayhem All Cutscenes | Full Game Movie (PS2) | 122 | |
| 11. | DazzlingWalkthroughs | Scooby Doo Mystery Mayhem PS2 Walkthrough - Part 03 | 115 | Walkthrough |
| 12. | ★WishingTikal★ | Scooby-Doo! Mystery Mayhem Walkthrough Part 1 (PS2, XBOX, GCN) No Commentary | 112 | Walkthrough |
| 13. | Mutch Games | Scooby-Doo! Mystery Mayhem [61] 100% GameCube Longplay | 109 | |
| 14. | Ghabulous Ghoti | The Sequel To My Childhood | Part 1 | Let's Play Scooby Doo: Mystery Mayhem | 99 | Let's Play |
| 15. |  Ngulik Games | Cara Bermain Game Scooby Doo Mystery Mayhem PS2 Di Android | 78 | |
| 16. | The Game Archive | Scooby-Doo! Mystery Mayhem Walkthrough | Episode 1 | Part 1 (Xbox/PS2/GameCube) | 64 | Walkthrough |
| 17. | Ghabulous Ghoti | Time for Midnight Snacks [All Food/Clue Locations] | Part 23 | Let's Play Scooby Doo: Mystery Mayhem | 63 | Let's Play |
| 18. | Ghabulous Ghoti | The Sixth Sense | Part 2 | Let's Play Scooby Doo: Mystery Mayhem | 60 | Let's Play |
| 19. | Geração Power Up | Velho Oeste Selvagem! - Scooby-Doo: Mystery Mayhem #03 (PS2) | 60 | |
| 20. | Storymodebae | Enough about Velma, Let’s Chill with Scooby and the Gang | 59 | |
| 21. | Maryo1st | Gamecube POV Scooby Doo Mystery Mayhem First Minutes 2023 | 56 | |
| 22. | Ultimate Gaming Dude | Scooby Doo! Mystery Mayhem PS2 Cutscenes | 55 | |
| 23. | Ultimate Gaming Dude | Scooby Doo! Mystery Mayhem PS2 100% Playthrough Part 1 | 54 | |
| 24. | DStation | O INÍCIO DOS SUSTOS | Scooby-Doo! Mystery Mayhem #1 | 54 | |
| 25. | Gui Santos | VELMA - A OUSADA SÉRIE QUE TÁ SENDO PERSEGUIDA KKKKKKK + DROPEI DESSA DESGRAÇA, CHEGA! | 53 | |
| 26. | Ghabulous Ghoti | Scaring Scooby | Part 21 | Let's Play Scooby Doo: Mystery Mayhem | 52 | Let's Play |
| 27. | 8BE | Scooby-Doo (GBA) | 8-Bit Eric and Chuckles Play | 8-Bit Eric | 50 | Review |
| 28. | Ghabulous Ghoti | The Ultimate Ghost [Finale] | Part 22 | Let's Play Scooby Doo: Mystery Mayhem | 45 | Let's Play |
| 29. | DazzlingWalkthroughs | Scooby Doo Mystery Mayhem PS2 Walkthrough - Part 05 | 44 | Walkthrough |
| 30. | Ghabulous Ghoti | Minigame Mayhem | Part 24 | Let's Play Scooby Doo: Mystery Mayhem | 44 | Let's Play |
| 31. | Ultimate Gaming Dude | Scooby Doo! Mystery Mayhem PS2 100% Playthrough Part 3 | 41 | |
| 32. | Ghabulous Ghoti | Scooby Doo: Mystery Mayhem (GBA) | Day 2 | The 12 Days of GhotiMas | 41 | |
| 33. | Lame Dad Retro Gamer | Scooby Doo Mystery Mayhem GameCube Review | 39 | Review |
| 34. | Geração Power Up | O Cavaleiro Vermelho! - Scooby-Doo: Mystery Mayhem #02 (PS2) | 37 | |
| 35. | Bepis Boys | Scooby-Doo! Mystery Mayhem - Intro | 36 | |
| 36. |  Nivas Gaming | Scooby Doo Mystery Mayhem Game with Game Play in Tamil | 36 | Guide |
| 37. | Geração Power Up | O Final da Caçada! - Scooby-Doo: Mystery Mayhem #05 (PS2) | 36 | |
| 38. | Ghabulous Ghoti | This Is My Swamp! | Part 12 | Let's Play Scooby Doo: Mystery Mayhem | 35 | Let's Play |
| 39. | Global Gaming | Scooby-Doo! Mystery Mayhem - ALL BOSSES | 35 | |
| 40. | Ultimate Gaming Dude | Scooby Doo! Mystery Mayhem PS2 100% Playthrough Part 2 | 34 | |
| 41. | Ghabulous Ghoti | Split | Part 5 | Let's Play Scooby Doo: Mystery Mayhem | 34 | Let's Play |
| 42. | Ghabulous Ghoti | Training With Sensei | 33 | |
| 43. | Global Gaming | Scooby-Doo! Mystery Mayhem - FULL GAME walkthrough | Longplay | 33 | Walkthrough |
| 44. | Geração Power Up | Olha o Nível! - Scooby-Doo: Mystery Mayhem #04 (PS2) | 33 | |
| 45. | Ghabulous Ghoti | [REMOVED, SEE BELOW] The Sequel to My Childhood | Part 1 | Let's Play Scooby Doo: Mystery Mayhem | 30 | Let's Play |
| 46. | Loopy Longplays | Scooby-Doo! Mystery Mayhem - Longplay Full Game Walkthrough (No Commentary) (Gamecube, Ps2, Xbox) | 29 | Walkthrough |
| 47. | Pixel Pursuit | Scooby-Doo! Mystery Mayhem | What Even is This Game!? | 29 | Review |
| 48. | Ghabulous Ghoti | Make It Stop | Part 25 | Let's Play Scooby Doo: Mystery Mayhem | 29 | Let's Play |
| 49. |  IntroGameOver | Intro Scooby-Doo! Mystery Mayhem [HD] | 29 | |
| 50. | It’s Moog | I Played the WORST Scooby Doo Video Game! (Scooby Doo! Mystery Mayhem) | 26 | |
| 51. | Rico Andry | Scooby Doo dan Shaggy balapan makan guys, siapa yang menang ya? | 26 | |
| 52. | CGRundertow | CGR Undertow - SCOOBY-DOO! MYSTERY MAYHEM review for Game Boy Advance | 26 | Review |
| 53. | LongplayArchive | Longplay of Scooby-Doo! Mystery Mayhem | 25 | |
| 54. | Ultimate Gaming Dude | Scooby Doo! Mystery Mayhem PS2 100% Playthrough Part 4 | 24 | |
| 55. | 40warrior | Let's Play Scooby Doo Mystery Mayhem ps2 part 1 - the gang is back | 23 | Let's Play |
| 56. | PurpleMapleLeaf | Scooby-Doo! Mystery Mayhem (GBA) Review | 23 | Review |
| 57. | Ghabulous Ghoti | [REMOVED, SEE BELOW] Overdue | Part 1 | Let's Play Scooby Doo: Mystery Mayhem (GBA) | 23 | Let's Play |
| 58. |  Group M Pro | Scooby-Doo! Mystery Mayhem (2004) GBA vs PS2 vs GameCube vs XBOX (Graphics Comparison) | 23 | |
| 59. | TASVideosChannel | [TAS] GBA Scooby-Doo! Mystery Mayhem by jlun2 in 47:13.42 | 23 | |
| 60. | LontraJogos | SCOOBY-DOO MYSTERY MAYHEM - O JOGO DE PS2, XBOX E GAMECUBE (PT-BR) | 22 | |
| 61. | Easy Allies Plays | Kyle Plays Scooby Doo! Mystery Mayhem | 22 | Let's Play |
| 62. | Rico Andry | Scooby Doo dan Shaggy dikejar Kesatria Topeng Merah | 22 | |
| 63. | Ghabulous Ghoti | Fred Is Useless | Part 7 | Let's Play Scooby Doo: Mystery Mayhem | 22 | Let's Play |
| 64. | Ultimate Gaming Dude | Scooby Doo! Mystery Mayhem PS2 100% Playthrough Part 5 (Final Part) | 21 | |
| 65. | Rico Andry | Final Boss dimana Scooby Doo VS Boss Terakhir Mystery Mayhem | 21 | |
| 66. | Ghabulous Ghoti | French Mustard | Part 6 | Let's Play Scooby Doo: Mystery Mayhem | 20 | Let's Play |
| 67. | John GodGames | Scooby-Doo! Mystery Mayhem - PS2 Playthrough 1080p Hi-Tech Terror (PCSX2) PART 5 | 20 | Let's Play |
| 68. | Enrique G. Gálvez | Scooby Doo (Game Boy Advance) | 20 | |
| 69. | Azza_Darklord_5 | Aaron's HD GamePlay - Scooby Doo Mystery Mayhem Episode 5 Part 2 - Mind Control | 19 | Show |
| 70. |  xTimelessGaming | Scooby-Doo! Mystery Mayhem PS2 Gameplay HD (PCSX2) | 18 | |
| 71. | Rico Andry | Selamatkan Freddy dan Daphne dari Badai Angin Topan | 17 | |
| 72. | RobertoLPDX | Let's Play: Scooby Doo! Mystery Mayhem (Longplay) | 17 | Let's Play |
| 73. | Rico Andry | Final Sambungan Pipa Telah Diperbaiki Scooby dan Shaggy | 17 | |
| 74. | John GodGames | Scooby-Doo! Mystery Mayhem - PS2 Playthrough 1080p Bad JuJu In the Bayou (PCSX2) PART 4 | 17 | Let's Play |
| 75. | Azza_Darklord_5 | Aaron's HD GamePlay - Scooby Doo Mystery Mayhem Episode 5 Part 3 - THE END | 16 | Show |
| 76. | Ghabulous Ghoti | Signs | Part 4 | Let's Play Scooby Doo: Mystery Mayhem | 16 | Let's Play |
| 77. |  Cls artz | como dibujar a VELMA MEETS THE ORIGINAL VELMA | ¿Qué es el Scooby Doo Monstruoso? | 16 | |
| 78. | TapersCrazy | Scooby Doo: Mystery Mayhem: Ep 1: Haunted Library | 16 | |
| 79. |  The Game Archivist | Scooby-Doo Mystery Mayhem | Full Game Walkthrough | No Commentary | 16 | Walkthrough |
| 80. | Azza_Darklord_5 | Aaron's GamePlay - Scooby Doo Mystery Mayhem Episode 2 Part 1 (HD test) | 16 | Show |
| 81. | ★WishingTikal★ | Scooby-Doo! Mystery Mayhem Walkthrough Part 2 (PS2, XBOX, GCN) No Commentary | 15 | Walkthrough |
| 82. | Is It Playable? | Is Scooby-Doo! Mystery Mayhem Playable? XBSX2 Performance [PS2 | Standalone] | 15 | |
| 83. | Jeremy Klinger | Scooby-Doo! Mystery Mayhem Review - Jeremy | 15 | Review |
| 84. | Ghabulous Ghoti | Broken | Part 20 | Let's Play Scooby Doo: Mystery Mayhem | 15 | Let's Play |
| 85. | Rico Andry | Asik Banget Scooby Doo dan Shaggy Pergi ke Bulan - Mystery Mayhem Episode 2 Part 1 | 15 | |
| 86. |  Vitt0xLar | Scooby-Doo! Mystery Mayhem on Ps4 | 14 | |
| 87. | DStation | O FANTASMA DE FOGO! | Scooby-Doo! Mystery Mayhem #10 (FIM) | 14 | |
| 88. | Mike's TOON TOWN | Cartoony Gameplay: Scooby-Doo! Mystery Mayhem PART 2 | 14 | |
| 89. | A Nice Idiot | Scooby Doo! Mystery Mayhem - PS2 Gameplay Full HD | PCSX2 | 13 | |
| 90. | Ultimate Gaming Dude | Scooby Doo! Mystery Mayhem PS2 Minigames: Mine Cart Ride | 13 | |
| 91. | ★WishingTikal★ | Scooby-Doo! Mystery Mayhem Walkthrough Part 3 (PS2, XBOX, GCN) No Commentary | 13 | Walkthrough |
| 92. | Azza_Darklord_5 | Aaron's GamePlay - Scooby doo Mystery Mayhem Intro / Episode 1 | 13 | Show |
| 93. | Easy Allies Plays | Kyle Plays Scooby-Doo! Mystery Mayhem (Pt. 2) | 13 | Let's Play |
| 94. | Camus Android | Scooby-Doo! Mystery Mayhem - no Athersx2 "PS2" Para Android+Download | 13 | |
| 95. | TheAnimefreak995 | Lets Play Scooby-Doo Mystery Mayhem Part 1 | 13 | |
| 96. | FuinhaGamerBR | Vamos Jogar: Scooby-Doo Mystery Mayhem #2 Primeiro Mistério resolvido (PT-BR) | 13 | |
| 97. | Mike's TOON TOWN | Cartoony Gameplay Scooby-Doo! Mystery Mayhem PART 3 | 13 | |
| 98. | LongplayArchive | Longplay of Scooby-Doo! Mystery Mayhem [New] | 12 | |
| 99. | Liam Keane | Scooby Doo Mystery Mayhem & Monster Mash - Acapella | 12 | |
| 100. |  CORE MEMORY UNLOCKED | SCOOBY DOO MYSTERY MAYHEM * FULL GAME [XBOX] | 12 | Walkthrough |
