| 2024-06-17 |  Orion Blair Phoenix Gaming | SERENA FULL INDIE GAME | 1:07:25 | 38 |
| 2022-09-14 |  Edgley Games | E's Laf - Gameplay with Serena (PC) [Playthrough/LongPlay] | 14:58 | 93 |
| 2022-03-28 |  RAITSI | kabur dari sekolah hantu - dimensi lain serena - game horor indonesia | let's Play Gameplay | 18:23 | 13 |
| 2022-01-18 | Ragekitt | This Redditor did WHAT to his wife?! [Serena Playthrough] | 39:27 | 38 |
| 2021-07-06 |  TheLousyLoser | Unterwegs in Düsterburg | #29: Katzengasse Nr. 5 | PC | Let's Play | 32:46 | 9 |
| 2020-10-06 |  Keith Ballard | Let's Play Serena - Do I Deserve to Be Forgiven? | 59:28 | 2,336 |
| 2020-06-24 | The RPG Chick | Let's Play Asylum (Demo - Blind), Part 1 of 4: Return to Hanwell Institute | 30:52 | 70 |
| 2020-05-25 | SqUiShY Gaming | Lost And Confused | Let's Play Serena | 22:43 | 10 |
| 2020-03-20 | theRCLman | 🕵️We're Little DETECTIVES!!!🕵️ | Kika & Daigo A Curious Tale Let's Play (w/ Serena) | 32:11 | 0 |
| 2019-08-10 |  Cam | Cam Plays: Prom Dreams | Part 8 | The Forger's Hand Ending | 55:19 | 142 |
| 2019-08-09 | Cam | Cam Plays: Prom Dreams | Part 7 | 53:36 | 122 |
| 2019-08-07 | Cam | Cam Plays: Prom Dreams | Part 5 | 45:37 | 97 |
| 2019-07-29 | Cam | Cam Plays: Prom Dreams | Part 4 | The Mastermind Ending | 56:56 | 160 |
| 2019-05-30 | wolfcub46 | Wolf Plays - Serena [Final] | 33:45 | 2 |
| 2019-05-28 | wolfcub46 | Wolf Plays - Serena [P1] | 31:34 | 3 |
| 2019-01-06 |  Jeajax | Let's play! Serena | 51:12 | 3 |
| 2018-12-12 | The Bigender Gamer | SERENA | Alex Replays | 40:41 | 12 |
| 2018-06-21 |  Avenclave | Let's Play SERENA #4 - Was für eine Tragödie! [Deutsch/German] | 18:44 | 4 |
| 2018-06-20 | Avenclave | Let's Play SERENA #3 - Wenn aus Liebe Hass wird [Deutsch/German] | 27:47 | 1 |
| 2018-06-14 | Avenclave | Let's Play SERENA #2 - Religiös, aber nicht prüde [Deutsch/German] | 24:37 | 2 |
| 2018-06-12 | Avenclave | Let's Play SERENA #1 - Verlorene Erinnerungen [Deutsch/German] | 20:45 | 20 |
| 2018-01-01 |  Hybridjunkie | Let's Play - Serena | 43:47 | 26 |
| 2017-10-09 | Aul In | Serena - Full Play Through | 1:02:47 | 3 |
| 2017-09-01 |  SilverDarkPhoenix | Serena - Playthrough ( Please Shoot Me In The Head ) | 51:29 | 25 |
| 2017-07-26 |  CorrosiveLick | Where did she go | Serena | CorrosiveLick Let's Play! | 21:18 | 8 |
| 2017-05-04 | iimjoeyy | SERENA FullPlaythrough! WHERE IS SERENA?! | iimjoeyy | 32:28 | 25 |
| 2017-02-11 |  Gold Styles (Goldstyles) | Serena - FINALE - Let's Play - Capitolo 3 | 26:48 | 11 |
| 2017-02-10 | Gold Styles (Goldstyles) | Serena - Let's Play - Capitolo 2 | 21:08 | 15 |
| 2017-02-09 | Gold Styles (Goldstyles) | Serena - Let's Play - Capitolo 1 | 21:29 | 19 |
| 2016-12-16 | Nessas Gamingzone | Plot-Twist! | Nessa spielt SERENA [Full Game] [Facecam, HD+] | 1:06:00 | 110 |
| 2016-10-01 | MoonlitWenny | OH MY GOD | Let's Play Serena | 42:41 | 4 |
| 2016-09-02 |  Tr1pw1re | The Truth Revealed! | Serena (PC) - Part 2 [End] | 23:50 | 8 |
| 2016-08-31 | Tr1pw1re | Alone In A Cabin | Serena (PC) - Part 1 | 28:11 | 18 |
| 2016-06-23 | Euclid | Let's Play Serena. Am I going crazy!? | 53:32 | 139 |
| 2016-02-18 | EmptyGarbageCan | Serena | 28:34 | 5 |
| 2016-01-25 | Rostbrot | Der Schrank | Let's Play Serena [German/Deutsch] #3 | 12:01 | 7 |
| 2016-01-24 | Rostbrot | Schuldgefühle und Ungewissheit | Let's Play Serena [German/Deutsch] #2 | 20:54 | 8 |
| 2016-01-23 | Rostbrot | Erinnerungen an die Liebe | Let's Play Serena [German/Deutsch] #1 | 20:49 | 51 |
| 2016-01-20 | Nick Munger | Let's Play Serena | MESSED. UP. STUFF. | 32:14 | 19 |
| 2015-12-11 | Radedo | AM I GOING CRAZY TOO? - Let's Play Serena Full Gameplay | 1:20:51 | 25 |
| 2015-12-06 | Spunkster | Serena - THE FEELS IS STRONG! - Full Playthrough | 34:55 | 5 |
| 2015-10-21 |  ScarabD | Scarab plays: Serena [003-END] - The Armoire | 22:49 | 11 |
| 2015-10-13 | ScarabD | Scarab plays: Serena [002] - The Vanity Table | 17:45 | 5 |
| 2015-10-07 | tacoline | Let's Play Serena pt 2 Fiery end | 28:11 | 1 |
| 2015-10-04 | Monmia | Let's Play an Indie Horror!_Serena [#2] | 17:28 | 4 |
| 2015-10-04 | Monmia | Let's Play an Indie Horror!_ Serena [#1] | 21:57 | 1 |
| 2015-10-04 | Emargy LPT | Let's Play Serena Part 02 - Enthüllungen - Finale | 29:12 | 3 |
| 2015-10-03 | tacoline | Let's Play Serena pt 1 Suddenly Rage | 32:34 | 9 |
| 2015-09-27 | Emargy LPT | Let's Play Serena Part 01 - Wo ist Serena? | 32:41 | 8 |
| 2015-08-27 | ThrashingBunny | Serena let's play (full game) | 54:01 | 16 |
| 2015-05-17 | Kraken | lets play serena click point adventure indie | 16:45 | 3 |
| 2015-03-30 |  LanokirX | Serena | Full Playthrough | 35:37 | 17 |
| 2015-02-17 | JAC OneManBand | Cabin In The Woods: JAC Plays: Serena | 50:29 | 49 |
| 2015-01-31 | TheIntendantS | Intendant S Plays Serena | 1:08:41 | 108 |
| 2015-01-31 | MartinSpielt | Serena - Let's Play - Teil 2/2 | 48:54 | 1,227 |
| 2015-01-29 | MartinSpielt | Serena - Let's Play - Teil 1/2 | 24:35 | 4,710 |
| 2014-09-22 | PoetryStud | Lets Play Serena - Indie Point and Click Game [#1] | 9:17 | 78 |
| 2014-06-25 | YagmanX | Wimpy Girl Plays Serena | That Ending?! | 23:38 | 1,528 |
| 2014-05-26 | bradye21 plays... | Let's Play Serena -3- Theres only one way anything can end (Finale) | 9:08 | 33 |
| 2014-05-20 | nekobun | Serena - Full Playthrough | 1:19:57 | 8 |
| 2014-04-25 | IceAngelQueen | Ice Plays: Serena - Part 1 | 25:31 | 4 |
| 2014-04-22 | Slail | Let's Play Serena - A One Part LP | 50:19 | 232 |
| 2014-04-13 | bradye21 plays... | Let's Play Serena -2- I hate her SO much | 17:49 | 46 |
| 2014-04-07 | bradye21 plays... | Let's Play Serena -1- Unsettling | 16:34 | 145 |
| 2014-03-17 | Vinithian | Let's Play Serena Part 5 | 12:32 | 13 |
| 2014-03-08 | UbuntuGamingProject | Let's Play on Ubuntu: Serena (Steam) | 11:11 | 150 |
| 2014-02-22 | 006Cronos | Let's Play: Serena (Part 2) | 16:33 | 77 |
| 2014-02-22 | 006Cronos | Let's Play: Serena (Part 1) | 18:05 | 145 |
| 2014-02-15 | Max Blackwing | Lets Play Serena: #To Spooky For Me!!~ | 53:20 | 80 |
| 2014-02-15 | The RPG Chick | Let's Play Serena (Blind), Part 3 of 3: Horror [FINAL EPISODE] | 17:19 | 91 |
| 2014-02-14 | The RPG Chick | Let's Play Serena (Blind), Part 2 of 3: Anger | 32:11 | 56 |
| 2014-02-13 | The RPG Chick | Let's Play Serena (Blind), Part 1 of 3: Sadness | 30:38 | 172 |
| 2014-02-12 | Fussball mit Heel Phakdi | Serena Let's Play #005 - The End![HD+][Deutsch] | 10:57 | 11 |
| 2014-02-12 | Vinithian | Let's Play Serena Part 4 Lamp destroyed my marriage (Commentary) | 13:39 | 23 |
| 2014-02-12 | Vinithian | Let's Play Serena Part 3 Perfume is not Magical (Commentary) | 11:48 | 96 |
| 2014-02-11 | Fussball mit Heel Phakdi | Serena Let's Play #004 - Kleine Wendung![HD+][Deutsch] | 15:16 | 3 |
| 2014-02-10 | Fussball mit Heel Phakdi | Serena Let's Play #003 - Wir haben sie umgebracht, oder?[HD+][Deutsch] | 14:01 | 7 |
| 2014-02-09 | CraigieG | Serena - Episode 2 - I finally understand....? | 16:39 | 23 |
| 2014-02-09 | Fussball mit Heel Phakdi | Serena Let's Play #002 - Wa(h)r(e)[s] Liebe?[HD+][Deutsch] | 12:51 | 3 |
| 2014-02-08 | NoAgendaStudios | Let's Play Serena | 1:07:04 | 2 |
| 2014-02-08 | Fussball mit Heel Phakdi | Serena Let's Play #001 - Wo bist du Serena?[HD+][Deutsch] | 17:31 | 29 |
| 2014-02-08 | Zalzar | Serena | IT BROKE MY HEART... | Gameplay Playthrough w/ facecam | 37:10 | 169 |
| 2014-02-07 | Elenkoism | Serena | Part 4 | Shocking Revelation | 12:40 | 14 |
| 2014-02-06 | Elenkoism | Serena | Part 3 | Heartless Slut!? | 13:17 | 70 |
| 2014-02-05 | Elenkoism | Serena | Part 2 | Confusion | 11:17 | 23 |
| 2014-02-04 | ZokkerBunny Jey | SERENA #02 | Die Wahrheit kommt ans Licht ҳ̸Ҳ̸ҳ Let's Play Serena | 49:19 | 33 |
| 2014-02-04 | ZokkerBunny Jey | SERENA #01 | Verloren gegangene Erinnerungen ҳ̸Ҳ̸ҳ Let's Play Serena | 29:25 | 79 |
| 2014-02-04 | Elenkoism | Serena | Part 1 | Free Indie Point and Click Game | 11:23 | 264 |
| 2014-02-04 | l0stw0lf | Serena - Free Creepy Indie Point & Click Narrative - Part (3/3) FINAL - l0stw0lf plays | 16:42 | 33 |
| 2014-02-03 | l0stw0lf | Serena - Free Creepy Indie Point & Click Narrative - Part (2/3) - l0stw0lf plays | 17:27 | 22 |
| 2014-02-03 | l0stw0lf | Serena - Free Creepy Indie Point & Click Narrative - Part (1/3) - l0stw0lf plays | 18:38 | 47 |
| 2014-02-03 | EchoLP | Angespielt | Serena [Part 3/3] - "Nur benutzt...?" | Let's Play Serena | German | HD | 22:11 | 43 |
| 2014-02-03 | Vinithian | Let's Play Serena Part 2 Might have been an accident ...(Commentary) | 11:54 | 37 |
| 2014-02-03 | Vinithian | Let's Play Serena Part 1 Why cant i remember (Commentary) | 7:29 | 39 |
| 2014-02-02 | CraigieG | Serena - Episode 1 - So confused... | 16:22 | 48 |
| 2014-02-02 | EchoLP | Angespielt | Serena [Part 2/3] - "Aus Liebe wird Hass" | Let's Play Serena | German | HD | 19:17 | 18 |
| 2014-02-01 | spudheds | Spudheds Plays - Serena - Full playthrough | 41:09 | 33 |
| 2014-02-01 | EchoLP | Angespielt | Serena [Part 1/3] - "Liebling, wo bist du?" | Let's Play Serena | German | HD | 20:35 | 70 |
| 2014-01-30 | Shook50 | Let's Play Serena (Suspensful, Spooky Point and Click Adventure) | 39:10 | 1,622 |
| 2014-01-30 | God is a Geek | Serena - Let's Play | 10:23 | 726 |
