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| 3. | ThisGuyKnowsSomeTech | How to Play Serious Sam: The Second Encounter on Android | ThisGuyKnowsSomeTech | #serioussamhd | 2,472 | Guide |
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| 9. | Boggy Gaming | Final Mission || Game #shorts | 917 | |
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| 13. | 365 Days Gamer | Final Mission | Serious Sam: The Second Encounter | Mission 12 The Grand Cathedral | PC Gameplay | 602 | |
| 14. | 365 Days Gamer | Serious Sam: The Second Encounter | Mission 4 Serpent Yards | PC Gameplay | Walkthrough | 586 | |
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| 16. | 365 Days Gamer | Serious Sam: The Second Encounter | Mission 6 Ziggurat | PC Gameplay | Walkthrough | 387 | |
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| 18. | 365 Days Gamer | Serious Sam: The Second Encounter | Mission 2 Valley Of The Jaguar | PC Gameplay | Walkthrough | 334 | |
| 19. | 365 Days Gamer | Serious Sam: The Second Encounter | Mission 5 The Pit | PC Gameplay | Walkthrough | 228 | |
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| 23. | 365 Days Gamer | Serious Sam: The Second Encounter | Mission 7 The Elephant Atrium | PC Gameplay | Walkthrough | 123 | |
| 24. | 365 Days Gamer | Serious Sam: The Second Encounter | Mission 9 Tower Of Babel | PC Gameplay | Walkthrough | 86 | |
| 25. | 365 Days Gamer | Serious Sam: The Second Encounter | Mission 8 Courtyards Of Gilgamesh | PC Gameplay | Walkthrough | 77 | |
| 26. | 365 Days Gamer | Serious Sam: The Second Encounter | Mission 10 The Citadel | PC Gameplay | Walkthrough | 71 | |
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| 48. | CloudCrafts | Serious Sam HD: The Second Encounter Playthrough (Part 2) Palenque - Sierra de Chiapas [1/3] | 24 | Let's Play |
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| 51. | RS INFINITY | Serious Sam: The Second Encounter PART-2 Malayalam Walkthrough | HD 1080P| RS INFINITY | 21 | Walkthrough |
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| 58. | RS INFINITY | Serious Sam: The Second Encounter PART-6 Malayalam Walkthrough | HD 1080P| RS INFINITY | 18 | Walkthrough |
| 59. | Boggy Gaming | Action Game || Attack on Alien Camp || Mission Day 6 | 18 | |
| 60. | MP Jamod | Serious Sam HD The Second Encounter Gameplay Part 1 | Ak56 Gaming [Live] | 17 | |
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| 62. | Boggy Gaming | Action Game || War with Alien || Mission Day 5 | 15 | |
| 63. | RS INFINITY | Serious Sam: The Second Encounter PART-7 Malayalam Walkthrough | HD 1080P| RS INFINITY | 14 | Walkthrough |
| 64. | GenTripleXS Force | Serious Sam The Second Encounter Part5 - Teotihuacan The Pit🤠🤠 | 13 | |
| 65. | RS INFINITY | Serious Sam: The Second Encounter PART-3 Malayalam Walkthrough | HD 1080P| RS INFINITY | 13 | Walkthrough |
| 66. | CloudCrafts | Serious Sam HD: The Second Encounter Playthrough (Part 1) Palenque - Sierra de Chiapas [1/3] | 12 | Let's Play |
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