| 101. |  Weebdeluxe | 1:07:15 | Let's Play: Sonic and Knuckles - Part 7 | 7:10 |
| 102. | MineTaker | 1:03:52 | Sonic & Knuckles Playthrough 7 | 9:28 |
| 103. |  a rat | 59:59 | Sonic and Knuckles Origins Full Playthrough | 59:59 |
| 104. | 2X gamers plus | 58:52 | Sonic and Knuckles good ending playthrough (Part 2) | Sonic Mania Plus | 32:10 |
| 105. |  SEGA MD2 | 55:52 | Sonic & Knuckles (Sega Genesis/Mega Drive) - Longplay | 55:52 |
| 106. | Michael Rowley | 54:00 | Sonic & Knuckles Sega Genesis 1994 Full Playthrough Playing As Hyper Sonic | 54:00 |
| 107. | Sapherno11 | 53:26 | Lets Play Sonic & Knuckles 3, Mushroom Hill Zone | 21:15 |
| 108. | Dragonite ZX | 51:37 | Sonic & Knuckles - Casual Playthrough with Knuckles | 51:37 |
| 109. | GothamLounge | 50:53 | Sonic & Knuckles Full Playthrough (As Knuckles) | 50:53 |
| 110. |  Lord Gamer | 49:43 | Lets Play Sonic & Knuckles SEGA GENESIS (HD) Part 1 Der Durchgang mit KNUCKLES | 33:02 |
| 111. | LaharlLP | 48:39 | Let's Play Sonic & Knuckles #004 Knuckles Weg | 12:32 |
| 112. | rynogt4 | 48:34 | Sonic 3 & Knuckles - Hidden Palace Zone & Sky Sanctuary Zone [Tails] (Let's Play Part 24) | 7:54 |
| 113. | Eric Corp Incorporated | 47:34 | Sonic the Hedgehog 3 & Knuckles (Genesis / Mega Drive) Playthrough Part 8 (Tails - Part 4 FINAL) | 47:34 |
| 114. | mrgameandpie | 47:01 | Lets Play Sonic and Knuckles Part 7: Victory hog | 11:33 |
| 115. |  Miggy | 46:49 | Sonic Advance 2 - Full Playthrough [Knuckles] | 46:49 |
| 116. | Therealm14 | 46:39 | Sky Sanctuary Zone Playthrough By Therealm14 | 7:43 |
| 117. |  Tomtil Lets plays | 43:45 | Sonic 3 AIR Let's Play Part 6 | 21:10 |
| 118. | KingSuperOne | 37:07 | Sandopolis/Lava Reef/Hidden Palace Zone (Sonic 3 & Knuckles) | Sonic Origins | 37:07 |
| 119. |  Terry Games | 36:07 | Sonic Mania Playthrough Part 1: The Return of 2D Sonic! | 36:07 |
| 120. | Baku | 33:56 | Let's Play Sonic 3 & Knuckles! (Knuckles) Final - Lava Reef, Hidden Palace and Sky Sanctuary | 19:52 |
| 121. | jojo1520 Productions | 32:38 | Sonic Mania - Sonic & Knuckles Lava Reef Zone Act 1 & 2 playthrough | 11:19 |
| 122. | Builder Mario - Nintendo Gameplays | 32:14 | Sonic Plays Sonic & Knuckles Part 2 | 12:36 |
| 123. | STAntics Arcade | 31:06 | FULL Play! Sonic and Knuckles - Part 5 | 8:00 |
| 124. | DSJ Brigade | 30:00 | DSJ Plays Sonic 3 and Knuckles 037: Now on to the Sonic and Knuckles Stages | 19:11 |
| 125. | Thundershot | 29:47 | Sonic Mania Knuckles Playthrough Part 10- Lava Reef Zone | 29:47 |
| 126. | AlexanderHilly | 29:22 | S3&K (Tails playthrough) Lava Reef Zone / Hidden Palace | 14:21 |
| 127. | dancentral | 29:21 | Let's Play: Sonic & Knuckles - Sega Mega Drive (Dancentral with Zonic) - Part 2 | 14:59 |
| 128. | SonKnuckLP | 28:41 | Let's Play 25 Years of Sonic - Sonic & Knuckles | 8:46 |
| 129. | Sabooshtin | 27:06 | A SONIC NERD PLAYS SONIC FRONTIERS| 4K PS5 PlayThrough Part#5 | Sonic & Knuckles #4k #walkthrough | 27:06 |
| 130. | bpblu | 25:55 | Sonic 3 & Knuckles Playthrough: Final Boss & The Doomsday | 9:37 |
| 131. | Chronicle2H | 25:43 | S3K playthrough: Sandopolis act 1 | 5:25 |
| 132. | mdmax09 | 25:34 | Sonic and Knuckles for the Genesis on the PS3 with Mikey's VideoGame Madness Commentary | 25:34 |
| 133. | Matthia Gryffine | 25:30 | Let's Play Sonic & Knuckles - Knuckles Episode 1: Living in Fast Forward | 17:08 |
| 134. | CephasRed VS. | 24:32 | NOT WASTING ANY TIME | S3: Knuckles (Part 3) | 24:32 |
| 135. | TippingForties | 23:43 | Let's Play Sonic's Ultimate Genesis Collection | 23:43 |
| 136. | corrytyn | 22:41 | Let's Play Sonic 3K PC Part 7 (Mushroom Hill) - Different Yet Familiar | 22:41 |
| 137. | Animus | 21:59 | Let's Play Sonic 3 & Knuckles Part 12- Sky Sanctuary Zone | 4:15 |
| 138. |  Green Hill Memories | 21:23 | [Let's Play #036] Sonic & Knuckles (Mega Drive - 1994) | 21:23 |
| 139. | knuxtoast | 20:55 | lets play s3&k part 5 ice is nice | 20:55 |
| 140. | Hibiki TMD | 20:51 | Hibiki Plays! : SONIC & KNUCKLES for SEGA GENESIS | 20:51 |
| 141. | Crow Continuum | 19:12 | Crow Plays Sonic & Knuckles with Sonic the Hedgehog 3 (Genesis) | 8:02 |
| 142. | eMPlay's Modetro | 18:33 | Sonic 3 : A.I.R - Knuckles - #15 - Flying Battery Zone - Act 1 | 6:45 |
| 143. | Toana | 18:06 | Let's Play-Sonic 3 Complete-Part 8 | 18:06 |
| 144. | HellfireComms | 17:50 | Sonic Adventure DX playthrough [Knuckles] [Part 5] | 7:42 |
| 145. | Shiro Paradox | 17:46 | Sonic 3 & Knuckles Hard Bosses Edition 2 ~ Playthrough (v400.0) (Knuckles) | 17:46 |
| 146. | Lightsaga | 16:28 | Let's play Sonic 3 & Knuckles (100% Sonic live run) Part 10 | 16:28 |
| 147. | ShinSubSmoke072Inaba | 16:27 | Sonic 3 & Knuckles (Knuckles Playthrough) Part 6: Marble Garden Zone Act 1 | 9:18 |
| 148. | SuperMSL | 16:09 | Let's Play Sonic 3 & Knuckles Part 19 - Mushroom Hill With Knuckles | 16:09 |
| 149. | TurflamicGaming420 | 15:53 | Ffej himself plays Sonic and Knuckles | 15:53 |
| 150. | Cutman Plays! | 15:40 | Dj CUTMAN Remixing Sonic and Knuckles [Highlights] - Cutman Plays | 15:40 |
| 151. | Collecting with Cory | 15:16 | Let's Play Something: Sonic & Knuckles | 15:16 |
| 152. | Classic Retro Game Room | 14:48 | Lets Play Sonic & Knuckles For The Sega Megadrive - Classic Retro Game Room | 14:48 |
| 153. | SG Wolfie | 14:42 | Wolfie Plays Sonic & Knuckles: Newtronic Panic (Pre SAGE 2020) - Werewoof Reactions | 14:42 |
| 154. | Red Legend | 14:30 | Let's Play: Sonic 3 & Knuckles - 100% Complete! #7 | 14:30 |
| 155. | The Maddieverse - Official Channel | 14:07 | Sonic & Knuckles Collection Let's Play #1: Angel Island | 14:07 |
| 156. | GuiasMaurelChile | 13:49 | LET'S PLAY: Sonic 3 & Knuckles PARTE: 7 Mushroom Hill Zone! (Empezando Sonic & Knuckles) | 13:49 |
| 157. | Tails' Channel | 13:40 | Matt and PKSparkxx (DatHottneSS) Play: Sonic 3 & Knuckles - Part 13 (FINALE) | 13:40 |
| 158. |  ArthurC | 13:28 | Best Moments - Sonic & Knuckles, Sonic CD | 13:28 |
| 159. | Jimothy Cool | 13:00 | Jimothy Plays a HIGH SPEED CLASSIC | 13:00 |
| 160. | parnash | 12:26 | Let's Play! Sonic and Knuckles and 3 and Knuckles and Sonic and Knuckles! Part 11! | 12:26 |
| 161. | GamingPox | 12:23 | Sonic Mania - Lava Reef Zone Playthrough - No Commentary | 12:23 |
| 162. | Martin's Games | 12:00 | Lets Play: Sonic & Knuckles (Sega Mega Drive / Genesis Game Play) | 12:00 |
| 163. | DamzTv gameplay | 11:48 | Helping BIG find FROGGY | Sonic Speed Simulator | 11:48 |
| 164. | Drak & Shadow Let's Plays | 11:10 | Drak and Shadow LP's: Sonic 3 & Knuckles (Knuckles) Part 1 - Wait Knuckles is the HERO!?!?!? | 11:10 |
| 165. | SonicMan2500 | 10:51 | Let's Play Sonic The Hedgehog 3 & Knuckles Pt.11 - Hidden Palace Zone & Sky Sanctuary Zone | 10:51 |
| 166. | sonicdx17 | 8:50 | Sonic 3 & Fluttershy Playthrough Part 11 Hidden Palace & Sky Sanctuary Zones | 8:50 |
| 167. | DeliciousCinnamon | 8:48 | DC plays Sonic and Knuckles - Ep 1 | 8:48 |
| 168. | Sharky2107 | 8:24 | Let's Play Sonic & Knuckles 3 {01} Tails we are going again | 8:24 |
| 169. | AdamantDitto | 7:55 | Let's Try That Again - Sonic 3 & Knuckles - Hidden Palace/Sky Sanctuary Zone 11/13 | 7:55 |
| 170. | Revegelance | 7:45 | Let's Play Sonic & Knuckles (as Knuckles) 48 - Marble Garden Zone, Act 1 | 7:45 |
| 171. | MrGTGS | 7:22 | Sonic and Knuckles plays Sonic forces | 7:22 |
| 172. | bahamut2k456 | 7:20 | So I Tried Starting a Sonic 3 and Knuckles Playthrough. | 7:20 |
| 173. | OsG Nightrider | 7:01 | OsG Plays | Sonic & Knuckles | 7:01 |
| 174. | UB-06 Austin | 6:57 | Austin Plays Sonic 3 Complete Finale: The Doomsday & Credits | 6:57 |
| 175. | Beer Banter Plays | 6:50 | Let's Play! Sonic & Knuckles - proof Captain Bob (is)n't a loser. | 6:50 |
| 176. | Robbob T (Memes) | 6:49 | Let's Play Sonic & Knuckles! | 6:49 |
| 177. | Leo Draconis | 5:28 | Sonic and Knuckles Knuckles Playthrough Complete | 5:28 |
| 178. | BlackFlame731 | 5:16 | Sonic Mania Plus - Knuckles & Knuckles Playthrough Part 13 - Final Boss & Ending | 5:16 |
| 179. | bambooie | 5:15 | Playthrough No 13. Sonic & Knuckles | 5:15 |
| 180. | TheGamerAtma | 5:06 | Sonic and Knuckles Video Playthrough Boss 1 | 0:27 |
| 181. | KingSpartaX37 | 4:31 | Cloudsdale Sanctuary [MLP FIM x Sonic and Knuckles] | 4:31 |
| 182. | LetsPlayShadigo | 3:55 | Let's Play Sonic & Knuckles (Sonic EXTRA) Special Zone Failures | 3:55 |
| 183. | RetroLand | 3:49 | Preacherman plays: sonic and knuckles. | 3:49 |
| 184. | xCamarox | 0:03 | Sonic and Knuckles plays chess with Mordecai and Rigby | 0:03 |
