| 1. |  Lil' Del | 286,368 | TEAM Sonic & Knuckles Siren Head VS TEAM Sonic.EXE & Knuckles.EXE CAUGHT on CAMERA.. | 8:55 |
| 2. | Faz Faz | 209,043 | Sonic and Knuckles have a bro moment - Sonic Frontiers | 1:36 |
| 3. | Miggy | 161,182 | Sonic 3 & Knuckles - The Doomsday Zone | 6:46 |
| 4. | SiIvaGunner | 29,095 | Lava Reef Zone (Act 2) & Hidden Palace Zone - Sonic the Hedgehog 3 & Knuckles | 1:42 |
| 5. | Official VGM | 13,183 | Mushroom Hill ~ Come On Mr Sonic - Sonic the Fighters Music Extended | 30:00 |
| 6. | Philip J. Fry II | 5,279 | Sonic Pocket Adventure OST | 53:39 |
| 7. | Arathrum | 4,676 | Sonic & Knuckles - Death Egg Zone Rock / Metal Cover || Arathrum | 3:57 |
| 8. | NexusShack | 2,999 | Key Hunters - SAGE 2019 Announcement Trailer | 0:33 |
| 9. | rㅤuㅤbㅤy | 1,382 | Sandopolis | Sonic & Knuckles (Remix) | 3:39 |
| 10. | RS 08 | 1,238 | Sonic 3 & Knuckles: Doomsday Zone and Good Ending! | 6:28 |
| 11. | LloydTheHammer | 714 | Sonic & Knuckles - Guitar Medley By LloydTheHammer | 7:02 |
| 12. | PrismaticAngel | 573 | Sonic 3 & Knuckles - Sky Sanctuary Zone (Knuckles) & Ending | 7:40 |
| 13. | Hedgeman98 | 78 | SHC 2020: Sonic & Knuckles Master Edition | 19:24 |
| 14. | Benelux Speedrunner Gathering | 41 | Sonic & Knuckles | Knuckles Beat the Game Glitchless Speedrun by huds601 | BSG Annual 2021 | 27:16 |
| 15. | Salty Josh | 8 | Sonic and Knuckles are responsible for Babysitting- Sonic Frontiers(#6) | 46:02 |
