| 1. |  Rerez | Spider-Man's Forgotten Worst Game - Just Bad Games | 2,255 | |
| 2. |  New Rockstars | Morbius Spiderman SINISTER SIX Theory! | RT | 559 | |
| 3. | Emergency Awesome | SPIDER-MAN: The Sinister Six Return and The Madame Web Apocalypse | 397 | Preview |
| 4. | Matt McMuscles | The WEIRDEST Spider-Man games ever made! - The Mediocre Spider-Matt | 378 | |
| 5. | ComicBookCast2 | Andrew Garfield is Still Hopeful About Amazing Spider-Man Sinister Six Movie Happening | 237 | |
| 6. | ShartimusPrime | Marvel Legends Spider-Man Sinister Six Collection Action Figure Cleaning Display Collection | 171 | |
| 7. | Screen Rant | Spider-Man: Sinister Six Members We Could See In No Way Home | 158 | |
| 8. | ComicBookCast2 | Spider-Man Sinister Six Film said to be Avengers Size MCU Entry | 157 | |
| 9. | Matt McMuscles | The Mediocre Spider-Matt - Spider-Man The Sinister Six (PC) | 150 | |
| 10. | Heavy Spoilers | Sony Confirm Spider-Man: Sinister Six Movie Is Being Built Towards In The MCU | 121 | |
| 11. | ComicBookCast2 | Sony Teases Spider-Man Sinister Six Film Plans & Spin-Off | 115 | |
| 12. | Final Flame Productions | Spider-Man: Sinister Six - Part 1. (GTA 5 Machinima) | 114 | |
| 13. |  Panels to Pixels | The WORST Spider-Man Game You've Never Played | 113 | |
| 14. |  FreYT | Spider-Man The Sinister Six "ITA" (Fan Film) RSproduction™ | 80 | |
| 15. | Final Flame Productions | Spider-Man: Sinister Six - Part 2. (GTA 5 Machinima) | 71 | |
| 16. | Ahra's Reviews - Action Figures & Collectibles | Marvel Legends Spider-man Sinister Six Box Set Toy Biz Action Figure Review Recensione | 67 | Review |
| 17. | Andrea Pannocchia | Spider-Man: The Sinister Six - [01/10] - PC English Walkthrough | 59 | Walkthrough |
| 18. |  RobertMan | (ESPAÑOL) SPIDERMAN - sinister six - marvel legens - 2004 - review | 55 | Review |
| 19. | Andrea Pannocchia | Spider-Man: The Sinister Six - English Longplay - No Commentary | 39 | Walkthrough |
| 20. | Lawrence Sonntag | Spider-Meh | Spider-Man: The Sinister Six Gameplay | 39 | |
| 21. | whisperingwind7 | Spiderman Sinister Six Statue by Art Asylum | 32 | |
| 22. | Chaos | Spider-Man SINISTER SIX Teaser - Far From Home Post Credit Scene Breakdown | 31 | Preview |
| 23. | Ahra's Reviews - Action Figures & Collectibles | Marvel Legends Green Goblin Spider-man Sinister Six Box Set Toy Biz Action Figure Review Recensione | 30 | Review |
| 24. | Electric Spider | Spider-Man The Sinister Six Stop Motion Film Teaser Trailer | 28 | |
| 25. | JP Sarri Reviews | Spider Man Sinister Six Review | 25 | Review |
| 26. | MakeOutHaven | Gta V | Spider-Man: Sinister Six Trailer | 23 | |
| 27. | zirkoni | DOS Game: Marvel Comics Spider-Man - The Sinister Six | 21 | |
| 28. | Ian Micheal | DREAMCAST SCUMMVM 2.8.0 New game Marvel Comics Spider-Man - The Sinister Six testing | 21 | |
| 29. | stryder HD | SPIDER-MAN: SINISTER SIX - Teaser Trailer (2025) New Marvel SONY Pictures Movie | StryderHD Concept | 20 | Preview |
| 30. | Final Flame Productions | Spider-Man: Sinister Six - FULL MOVIE (GTA 5 Machinima) | 20 | |
| 31. |  Level Proders | XM Studio Spiderman : Sinister Six Rhino | 18 | |
| 32. |  Brave Lionheart | rerez just bad games series: spiderman the sinister six pc game reaction | 11 | |
| 33. | Electric Spider | Spider-Man The Sinister six & Maximum Carnage Teaser trailer | 11 | |
| 34. | Andrea Pannocchia | Spider-Man: The Sinister Six - [10/10] - PC English Walkthrough | 9 | Walkthrough |
| 35. |  GamerGeeks | Spider-Man: Sinister Six (PC/DOS) - Retro Review - Mijn eerste Spidey game! | 8 | Review |
| 36. | 21st FPS | SPIDERMAN: Sinister Six Assemble & Mysterio illusion | Figure Stopmotion | 7 | |
| 37. | Andrea Pannocchia | Spider-Man: The Sinister Six - [05/10] - PC English Walkthrough | 7 | Walkthrough |
| 38. | 21st FPS | Spider Man: Sinister Six in The Spider-verse | Official Trailer | 7 | Preview |
| 39. | GET OFF MY LAWN | Random DOS Game Show #256: Spider-Man: The Sinister Six (1996) | 7 | |
| 40. | NERDSoul | Spider-Man: Revenge of the Sinister Six, My First Comic Book | NERDSoul | 7 | |
| 41. | FreYT | Spider-Man The Sinister Six: Soundtrack (EPIC VERSION) By FreYTRPChannel | 6 | |
| 42. | Saxcat's Gaming Corner | Spider-Man: The Sinister Six [1] Spider-Man had a Point and click game | 6 | |
| 43. | Andrea Pannocchia | L'Uomo Ragno: I Sinistri Sei - Longplay in italiano - Senza commento | 5 | Walkthrough |
| 44. | Slyfincleton | The Weird Spider-Man Point-and-Click Game Nobody Remembers (Spider-Man: The Sinister Six) | 5 | |
| 45. | Andrea Pannocchia | Spider-Man: The Sinister Six - [06/10] - PC English Walkthrough | 4 | Walkthrough |
| 46. | Andrea Pannocchia | Spider-Man: The Sinister Six - [08/10] - PC English Walkthrough | 4 | Walkthrough |
| 47. | Andrea Pannocchia | Spider-Man: The Sinister Six - [09/10] - PC English Walkthrough | 4 | Walkthrough |
| 48. |  IDKG - I Don't Know Games | Spider-Man: The Sinister Six | Stargame Multishow | 4 | Show |
| 49. |  DarkHunter TV | SPIDER-MAN LOS SEIS SINIESTROS (1996) Juego Completo ESPAÑOL [AVENTURA GRÁFICA] Historia Completa | 4 | |
| 50. |  DIEGO SPIDER 2099 JR | Amazing Spider Man Sinister Six.wmv | 4 | |
| 51. | Andrea Pannocchia | Spider-Man: The Sinister Six - [02/10] - PC English Walkthrough | 4 | Walkthrough |
| 52. | TJ Wolf | Spider-Man: Sinister Six Reborn Part 1 Review (Part 1 of 2) | 4 | Review |
| 53. | Danoby2 | Hot Toys Spider-Man Sinister Six Short Danoby2 Doc Ock#Spiderman #hottoys #sonyplaystation | 4 | Let's Play |
| 54. | Andrea Pannocchia | Spider-Man: The Sinister Six - [03/10] - PC English Walkthrough | 4 | Walkthrough |
| 55. | Le Shape YT | Lego Spider-Man: the Sinister Six series (I guess). | 3 | |
| 56. | FreYT | scena bruttissima il doppiaggio su Spider-Man the Sinister Six... | 3 | |
| 57. | Saxcat's Gaming Corner | Spider-Man: The Sinister Six [2] So...why did Spider-Man have a Point and click game? | 3 | |
| 58. | Brandon Culberson | Unboxing New Spider-Man Sinister Six Funko Pop Set | 3 | |
| 59. | Martin el Nerd | Todos los Juegos de Spider-Man - Parte 1 (1982-1996) | 3 | |
| 60. | Runplays in HD | 2521 Spider-Man The Sinister Six PC Windows 1440p 60fps | 3 | Let's Play |
| 61. | Andrea Pannocchia | L'Uomo Ragno: I Sinistri Sei - [06] - Soluzione in italiano - Senza commento | 2 | Walkthrough |
| 62. | powerlegen23 | spider man sinister six vulture ,lizard ,sandman ,dr Otto rhino, scorpion, electrio, | 2 | |
| 63. | Parks and Pops | Spider-Man Sinister Six Funko POPS ON SALE!!! #funkopop | 2 | |
| 64. |  Game Thích | Spider Man The Sinister Six [Srceen Glitch No] Win 98 Lite Limbo PC x86 ARMv7 Emulator Android 2022 | 2 | |
| 65. | Jeffrey Scarbrough Board Games&Geek things | #marvel Spider-Man sinister six board games unboxing | 2 | |
| 66. | Andrea Pannocchia | L'Uomo Ragno: I Sinistri Sei - [02] - Soluzione in italiano - Senza commento | 2 | Walkthrough |
| 67. | Hipolito Pichardo | Spider-Man: The Sinister Six game ending - Adventure Quest #39 | 2 | |
| 68. | Maverick BFG | Marvel's The Amazing Spider-Man: Sinister Six escape | 2 | |
| 69. | TechNinja516 | SPIDER-MAN: The SINISTER SIX?!? (Gameplay #12) | 1 | |
| 70. |  SECRET IS BACK | Spider-man Sinister Six PC gameplay Part 2 | 1 | |
| 71. | Andrea Pannocchia | Spider-Man: The Sinister Six - [07/10] - PC English Walkthrough | 1 | Walkthrough |
| 72. |  Daimao Strizer | Spider-Man The Sinister Six DOS #Shorts | 1 | |
| 73. | TJ Wolf | Spider-Man: Sinister Six Reborn Part 1 Review (Part 2 of 2) | 1 | Review |
| 74. | Slyfincleton | Spider-Man: The Sinister Six (1996) Playthrough | 1 | Let's Play |
| 75. |  Rick M | Spider-Man Sinister Six Marvel Vs DC | 1 | |
| 76. | Andrea Pannocchia | Spider-Man: The Sinister Six - [04/10] - PC English Walkthrough | 1 | Walkthrough |
| 77. | Andrea Pannocchia | L'Uomo Ragno: I Sinistri Sei - [01] - Soluzione in italiano - Senza commento | 1 | Walkthrough |
| 78. | Elvin Garcia | Sony/Columbia Pictures/Marvel Studios/Pascal Pictures (Spider-Man: SINISTER SIX Variant) | 1 | |
| 79. | theDEMION | #Spiderman the sinister six | 1 | |
| 80. | Film Royalty | SPIDER-MAN: SINISTER SIX Teaser (2024) With Tom Holland & Jamie Foxx | 1 | Preview |
