| 1. |  Scotty's HD Gaming Channel! | Syphon Filter: The Omega Strain PlayStation 2 Classic on PS3 in HD 1080p | 34,545 | Let's Play |
| 2. | Pandutney | [100% Full Playthrough R1 To T4] Syphon Filter: The Omega Strain | 8,675 | Let's Play |
| 3. | Lunethex | [Let's Play] Syphon Filter Omega Strain Episode 3-2 - Yemen | 5,747 | Let's Play |
| 4. | Lunethex | [Let's Play] Syphon Filter Omega Strain Episode 2-2 - Belarus | 5,692 | Let's Play |
| 5. | Lunethex | [Let's Play] Syphon Filter Omega Strain Episode 4-2 - Minsk, North Atlantic | 5,496 | Let's Play |
| 6. | Lunethex | [Let's Play] Syphon Filter Omega Strain Episode 5-1 - Japan, Myanmar | 5,093 | Let's Play |
| 7. | Lunethex | [Let's Play] Syphon Filter Omega Strain Episode 3-1 - Kyrgyzstan | 4,726 | Let's Play |
| 8. | Pandutney | [TOS Overhaul Mod v1.0.2 Beta Single Segment Playthrough Offline] Syphon Filter: The Omega Strain | 2,766 | Let's Play |
| 9. | IGN | Syphon Filter: The Omega Strain PlayStation 2 Gameplay | 2,234 | Let's Play |
| 10. | Lunethex | [Let's Play] Syphon Filter Omega Strain Episode 2-3 - Italy & Belarus Codec Calls | 2,144 | Let's Play |
| 11. | Lunethex | [Let's Play] Syphon Filter Omega Strain Episode 4-BONUS - Acrobatic Marvel | 1,917 | Let's Play |
| 12. | IGN | Syphon Filter: The Omega Strain PlayStation 2 Gameplay - | 1,253 | Let's Play |
| 13. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 560 | Let's Play |
| 14. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 442 | Let's Play |
| 15. | IGN | Syphon Filter: The Omega Strain PlayStation 2 Gameplay - | 294 | Let's Play |
| 16. | Sport Cards Brass Trains VideoGames | Syphon Filter The Omega Strain - PlayStation 2 PS2 Intro Gameplay | 218 | Let's Play |
| 17. | STARZ Gaming | Syphon Filter Omega Strain [1] Whole New Experience (Lets Play) | 175 | Let's Play |
| 18. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 136 | Let's Play |
| 19. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 102 | Let's Play |
| 20. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 95 | Let's Play |
| 21. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 89 | Let's Play |
| 22. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 85 | Let's Play |
| 23. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 82 | Let's Play |
| 24. | STARZ Gaming | Syphon Filter Omega Strain [9] Sorry But Im Done (Lets Play) | 80 | Let's Play |
| 25. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 79 | Let's Play |
| 26. | STARZ Gaming | Syphon Filter Omega Strain [6] I Love This Gun (Lets Play) | 74 | Let's Play |
| 27. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 73 | Let's Play |
| 28. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 67 | Let's Play |
| 29. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 67 | Let's Play |
| 30. | STARZ Gaming | Syphon Filter Omega Strain [2] Shes Not Playing (Lets Play) | 65 | Let's Play |
| 31. | STARZ Gaming | Syphon Filter Omega Strain [5] Thought I was Doing Good (Lets Play) | 60 | Let's Play |
| 32. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 59 | Let's Play |
| 33. | STARZ Gaming | Syphon Filter Omega Strain [4] How Far Is The Shelter (Lets Play) | 56 | Let's Play |
| 34. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 53 | Let's Play |
| 35. | STARZ Gaming | Syphon Filter Omega Strain [8] Escape The Labs (Lets Play) | 53 | Let's Play |
| 36. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 41 | Let's Play |
| 37. | STARZ Gaming | Syphon Filter Omega Strain [7] Why You Taking So Long (Lets Play) | 39 | Let's Play |
| 38. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 37 | Let's Play |
| 39. | STARZ Gaming | Syphon Filter Omega Strain [3] Grenades (Lets Play) | 37 | Let's Play |
| 40. | IGN | Syphon Filter: The Omega Strain PlayStation 2 | 21 | Let's Play |
