| 2025-02-02 |  GuardianOfFey | Yo, playing some Binding of Isaac and then an indie title called Scatchin' Melodii. Let's rap😄��� | 0:00 | 5 |
| 2023-12-16 | Himsl Games | Adobe Flash Explained In Binding of Isaac! | 15:24 | 115,530 |
| 2023-10-07 | Himsl Games | Save Files Explained in the Binding of Isaac! | 10:26 | 14,885 |
| 2022-11-19 | nopstr | Insane Builds | Isaac Stream #4 | 10:24:49 | 163 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix Not Working! | Complete 2022 Tutorial | 3:06 | 280 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix Crashing on Startup! | Complete 2022 Tutorial | 3:16 | 2,464 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix Not Launching/Opening! | Complete 2022 Guide | 3:16 | 3,469 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix Connection/Server Issues! | Complete 2022 Tutorial | 3:14 | 73 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix High Ping! | Complete 2022 Guide | 2:42 | 3 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix Low FPS/Lagging! | Complete 2022 Tutorial | 4:18 | 5,745 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix Crash/Crashing! | Complete 2022 Tutorial | 3:32 | 2,129 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix Errors/Issues! | Complete 2022 Guide | 3:17 | 69 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix Black Screen! | Complete 2022 Tutorial | 3:21 | 955 |
| 2022-10-03 | fix IT | Binding of Isaac – How to Fix No Audio/Audio Issues! | Complete 2022 Tutorial | 3:48 | 1,989 |
| 2022-07-31 | orizuru | Binding of Isaac Wrath of the Lamb - Isaac vs Satan - D6 + ... + D20 (all items in the description) | 1:00:29 | 1 |
| 2022-07-28 | orizuru | Binding of Isaac Wrath of the Lamb - Isaac vs Satan - Magic Mushroom + The Relic + Boom! | 58:05 | 9 |
| 2022-07-24 | orizuru | Binding of Isaac Wrath of the Lamb - Cain vs Satan - Demon Baby + Moms Heels + My Reflection + Boom! | 53:27 | 1 |
| 2022-07-21 | orizuru | Isaac vs Blue Baby - D6 + 16 items (all in the description) - Binding of Isaac Wrath of the Lamb | 1:06:36 | 5 |
| 2022-07-17 | orizuru | Binding of Isaac Wrath of the Lamb - Eve vs Satan - Bob´s rotten Head + Polyphemus + Mitre + Gamekid | 56:12 | 5 |
| 2022-07-13 | orizuru | Binding of Isaac Wrath of the Lamb - Samson vs Statan - My little Unicorn + Mitre + Polyphemus | 57:38 | 2 |
| 2022-07-08 | orizuru | Binding of Isaac Wrath of the Lamb - Isaac beating Isaac - Dr. Fetus + The Virus + Harlequin Baby... | 59:25 | 2 |
| 2022-07-04 | orizuru | Binding of Isaac Wrath of the Lamb - Magdalene vs Statan - Little Gish + D20 + The Peeper! | 1:04:56 | 0 |
| 2022-06-29 | orizuru | Binding of Isaac Wrath of the Lamb - Blue Baby vs Statan - Wh. of Babylon + Dr. Fetus + Mr. Mega | 50:19 | 2 |
| 2022-06-25 | orizuru | Binding of Isaac Wrath of the Lamb - Isaac beating Isaac - (1x) D6 + C o t vampire + Chemical Peel.. | 1:07:39 | 4 |
| 2022-06-18 | orizuru | Binding of Isaac Wrath of the Lamb - Judas vs Satan - Lokis Horns + Magneto + Tough Love | 52:15 | 1 |
| 2022-06-15 | orizuru | Binding of Isaac Wrath of the Lamb - Blue Baby beating Isaac - B o t M + Mulligan + Bobs Curse ... | 52:49 | 9 |
| 2022-06-12 | orizuru | Binding of Isaac Wrath of the Lamb - Cain beating Isaac - Odd + Magic Mushroom + Infest. + Ipecac... | 58:21 | 2 |
| 2022-06-10 | orizuru | Binding of Isaac Wrath of the Lamb - Maggy beating Isaac - Tech. 2 + Bucket of Lard + Pinking Shears | 1:05:51 | 1 |
| 2022-06-06 | orizuru | Binding of Isaac Wrath of the Lamb - Eve beating Isaac - Mut. Spid. + S o t N + Candle + Epic Fetus | 51:17 | 3 |
| 2022-06-01 | orizuru | Binding of Isaac Wrath of the Lamb - Judas beating Isaac - Max´s Head + Scapular + Odd Mushroom | 43:53 | 2 |
| 2022-05-25 | orizuru | Binding of Isaac Wrath of the Lamb - Samson vs. Isaac - Inner Eye + Polyphemus + Mutant Spider... | 52:06 | 10 |
| 2022-04-21 | Muffet | The Binding of Isaac: Rise goes to the Lamb and Game ends him | 29:49 | 7 |
| 2021-11-28 | Biggy&Stepsi | The Binding of Isaac: Repentanc 💀 Auf der such nach den Tainted Charakters 🍄 | 0:00 | 38 |
| 2021-08-08 | Biggy&Stepsi | The Binding of Isaac 💀 Challenge #27 Brains ⭕️ | 48:32 | 34 |
| 2021-08-04 | Biggy&Stepsi | Was ist den mit Hush Los ??? 🤣 The Binding of Isaac 💀 | 40:05 | 39 |
| 2021-07-29 | Biggy&Stepsi | Was ist das den für ein Extremer Run 😱 The Binding of Isaac 💀 | 57:49 | 61 |
| 2021-07-17 | Himsl Games | Binding of Isaac Eternal Edition Explained! | 6:08 | 6,170 |
| 2021-04-25 | PKWeegee1337 | Binding of Isaac: Repencance - Stream 9 | 1:34:05 | 2 |
| 2021-04-10 | PKWeegee1337 | Binding of Isaac: Repetance - Stream 2 | 1:04:15 | 1 |
| 2021-04-05 | PKWeegee1337 | The Binding of Isaac: Repetance - Stream 1 | 1:38:13 | 9 |
| 2021-03-28 | Himsl Games | Binding of Isaac explained! The Horsemen! | 5:12 | 6,068 |
| 2020-12-05 | Himsl Games | Binding of Isaac Explained! Hats and Characters | 6:34 | 6,469 |
| 2020-11-03 | 47 Gang | The Binding of Isaac 1 | 11:41 | 54 |
| 2020-10-09 | Himsl Games | Binding of Isaac Explained! Doors and Room Transitions. | 6:36 | 5,334 |
| 2020-09-11 | Himsl Games | Binding of Isaac Explained! Synergies!! | 9:04 | 3,740 |
| 2020-08-14 | Himsl Games | Binding of Isaac Explained: Bosses! | 13:22 | 12,418 |
| 2020-07-18 | Himsl Games | Binding of Isaac Explained! Homing Bullets and AI! | 10:06 | 3,632 |
| 2020-06-19 | Himsl Games | Binding of Isaac Explained: Orbitals! | 12:08 | 4,334 |
| 2020-05-22 | Himsl Games | Isaac's Movement Explained! | 12:26 | 5,289 |
| 2020-05-08 | Himsl Games | Pathfinding Explained in the Binding of Isaac! | 9:36 | 6,566 |
| 2020-05-01 | Himsl Games | Binding of Isaac Explained! Physics! | 12:29 | 7,292 |
| 2020-02-15 | Muffet | The Binding Of Isaac Vanilla Maggy Good | 51:25 | 33 |
| 2020-02-08 | Muffet | The Binding of Isaac Maggy Run | 42:56 | 21 |
| 2019-12-27 | Muffet | The binding of Isaac Test Stream Part 2 | 18:29 | 4 |
| 2019-09-30 | Himsl Games | A New Game by Binding of Isaac Programmer! | 4:38 | 3,020 |
| 2019-09-29 | ThePurpleBlackDragon | 'RS' A Grim Love -A girlfriend of Death- | 11:58 | 7 |
| 2018-06-06 | Alextv98 | Do it! - Friendgesteuert | mit Rappi und The Binding of Isaac | #1 | 1:05:01 | 11 |
| 2017-12-26 | Estrana | Blut und Tränen auf all meinen Wegen | The Binding of Isaac | 59:47 | 17 |
| 2017-06-11 | Himsl Games | Binding of Isaac Reflash! (Let's Play) | 46:04 | 908 |
| 2017-04-12 | BLOGDOT.TV | 8DAYS DEMO PlayStation 4 - PSN Downloads | 2:23 | 30 |
| 2017-03-01 | Himsl Games | Ebba reacts to her 15 minutes of fame. | 54:27 | 514 |
| 2017-01-02 | Himsl Games | Edmund reveals exclusive item for AB+? | 13:34 | 4,349 |
| 2016-10-20 | Himsl Games | Reminiscing with Edmund McMillen! (Part 3) | 55:45 | 2,280 |
| 2016-10-05 | Himsl Games | Reminiscing with Edmund McMillen! (Part 1) | 14:10 | 6,528 |
| 2016-09-24 | WWEdeadman | Let's Play The Binding of Isaac: Eternal Edition - Part 7 | 48:39 | 70 |
| 2016-04-06 | Himsl Games | Afterbirth Plus: suggest your items now says Edmund | 1:34 | 381 |
| 2016-03-20 | Bebo Bastard | Most overpowered Binding of Isaac run? | 3:17 | 53 |
| 2016-03-13 | Himsl Games | Binding of Isaac! #122 I remember these! | 53:19 | 132 |
| 2016-02-14 | Himsl Games | Binding of Isaac! #94 Jera and Blank Card? | 1:08:43 | 51 |
| 2016-02-10 | Himsl Games | Binding of Isaac! #91 Where are my Glitterbombs?? | 1:42:14 | 69 |
| 2016-02-10 | Himsl Games | Binding of Isaac! #90 So Many blue hearts! | 1:40:16 | 2,783 |
| 2016-02-08 | Himsl Games | Binding of Isaac! #88 Lilith! | 48:41 | 40 |
| 2016-02-06 | Himsl Games | Binding of Isaac! #86 To Unlock a Rune! | 1:03:55 | 2,878 |
| 2016-01-24 | Himsl Games | Binding of Isaac! #73 Need to Sacrifice | 1:14:36 | 63 |
| 2016-01-20 | Himsl Games | Binding of Isaac! #69 Spiders! | 53:31 | 40 |
| 2016-01-06 | Himsl Games | Binding of Isaac! #56 please Wrath! | 1:03:38 | 41 |
| 2015-12-25 | Himsl Games | Binding of Isaac! #45 Balls of Steel | 48:31 | 63 |
| 2015-12-20 | Himsl Games | Binding of Isaac! #39 Catacombs | 1:13:07 | 65 |
| 2015-12-15 | Himsl Games | Binding of Isaac! #216 Classic | 48:55 | 130 |
| 2015-12-01 | Himsl Games | Binding of Isaac! #24 Reoccuring fatties | 1:26:12 | 64 |
| 2015-11-30 | Himsl Games | Binding of Isaac! #23 Heart or bust | 1:03:48 | 47 |
| 2015-11-18 | Himsl Games | Binding of Isaac! #215 Unlucky Cain | 29:21 | 103 |
| 2015-11-17 | Himsl Games | Binding of Isaac! #12 Lazarus many lives | 53:02 | 55 |
| 2015-11-15 | Himsl Games | Binding of Isaac! #10 Cyclopes | 40:03 | 86 |
| 2015-11-14 | Himsl Games | Binding of Isaac! #216 return of the guppy items | 1:16:15 | 132 |
| 2015-11-12 | Himsl Games | Binding of Isaac! #215 I am back home! | 53:34 | 60 |
| 2015-11-08 | Himsl Games | Binding of Isaac! #214 Paul is baby | 53:13 | 75 |
| 2015-11-07 | Himsl Games | Binding of Isaac! #213 Paul plays eternal mode | 38:21 | 172 |
| 2015-11-06 | Himsl Games | Binding of Isaac! #212 SO much damage! | 53:20 | 97 |
| 2015-11-04 | Himsl Games | Binding of Isaac! #211 Better summon the bird | 48:20 | 110 |
| 2015-11-02 | Himsl Games | Binding of Isaac! #210 Penetration Vomit! | 55:39 | 142 |
| 2015-11-01 | Himsl Games | Binding of Isaac! #209 Isaac so vanilla | 1:04:03 | 99 |
| 2015-10-30 | Himsl Games | Binding of Isaac! #208 Isaac's Fate | 1:08:10 | 82 |
| 2015-10-29 | Himsl Games | Binding of Isaac! #207 Paul is back! | 1:36:03 | 97 |
| 2015-10-28 | Himsl Games | Binding of Isaac! #206 Natalie | 42:04 | 96 |
| 2015-10-27 | Himsl Games | Binding of Isaac! #205 laser Eve! | 57:17 | 91 |
| 2015-10-26 | Himsl Games | Binding of Isaac! #204 overpowered Wrath | 1:00:58 | 108 |
| 2015-10-25 | Himsl Games | Binding of Isaac! #203 Hateful Dieter | 59:45 | 97 |
| 2015-10-24 | Himsl Games | Binding of Isaac! #202 Samsons Laser Rage | 1:00:02 | 91 |
| 2015-10-23 | Himsl Games | Binding of Isaac! #201 Eves mamy Hearts! | 55:51 | 86 |
