1. | bisnap | 792 | Bisnap Streams Isaac: Eternal - Part 8 | 32:10 |
2. | Wolv21 | 352 | The Binding of Isaac - BOILeR Timed Runs - Set a Goal | 22:47 |
3. | green9090 | 255 | The Binding of Isaac Head to Head ep 120 | 44:20 |
4. | ZackScottGames | 225 | The Binding of Isaac: Wrath of the Lamb - Part 148 - Just Watch This One | 43:24 |
5. | DumbDog | 213 | TheLost.mov | 1:25 |
6. | crumps2 | 205 | Binding of Isaac ??? hardmode runs for completion | 0:00 |
7. | bobfleadip | 177 | AGNB Plays: The Binding of Isaac - Episode 169 | 0:00 |
8. | Dan Gheesling | 158 | What's your favorite Isaac Mod? #bindingofisaac #isaacmod #streamer | 0:46 |
9. | Mitch Rapp Gaming | 151 | Channel Update! | 7:48 |
10. | NAM | 148 | The two Flash Isaac runs from my 30th birthday stream. | 3:29:21 |
11. | Killmehord | 139 | The Binding of Isaac: Ep 140 Judas Popping off??? | 0:00 |
12. | SgtKeeneye | 134 | SgtKeeneye Talks - Important Channel Update/Question | 15:00 |
13. | Mity80 | 127 | Binding of Isaac 158 Challenge 42 Hot Potato | 33:26 |
14. | Gameraiders101 | 116 | Trying to 100% my Binding of Isaac Save... | 3:05:13 |
15. | Olexa | 115 | This is the BEST Binding of Isaac Seed for the Holidays | 51:35 |
16. | OniGamer | 108 | ISAAC ISAAC ISAAC ISAAC ISAAC ISAAC ISAAC | 0:00 |
17. | NeatoCheeto | 107 | Playing With NeatoCheeto: Binding of Isaac (Episode 100 Finale) | 1:03:16 |
18. | Chronos | 106 | Chronos Plays The Binding of Isaac #106: Finally | 57:12 |
19. | uidsea | 102 | Bloodsplosion?! | Afterbrith Plus Modded Rotation | Episode 5 | 43:19 |
20. | nintenrob | 96 | outer limits gaming the binding the isaac 7 19 17 | 28:03 |
21. | iHasCupquake | 96 | The Binding of Isaac Wrath of the Lamb Ep 33 | 1:20:18 |
22. | Omnigryphon | 89 | Eternal Isaac - 6 - Fickle Game | 42:10 |
23. | Czech Sheen | 81 | The Binding of Isaac - 8.1.2018 | 1:45:47 |
24. | Sinvicta | 81 | THE JUDGING OF ISAAC: FIRE MIND | 0:00 |
25. | GZewewelous | 78 | The Binding of Isaac Ep.78 Eternal Cain Part 2 | 9:39 |
26. | Vinrafel | 74 | Pitiful Isaac - Binding of Isaac #74 | 11:34 |
27. | Zexxios | 73 | [The Binding of Isaac] - Final 3 item touches for DEAD GOD!!! | 2:51:59 |
28. | Foeman | 73 | Just a Chill Guy Playing Isaac! | 0:00 |
29. | El Blargho | 71 | What if You Mashed Together Spelunky and The Binding of Isaac? { SPIRITS ABYSS } | 40:36 |
30. | SenseiPeeper | 67 | The Epic Fetus Incident | 0:00 |
31. | Rawrzaur | 61 | The Binding Of Isaac: Another Greed Run | 1:46:15 |
32. | Tannaut | 60 | The Binding Of Isaac Part 62!! I Need Help | 29:13 |
33. | Sunheavy | 60 | The Binding of Isaac: Rageplay w/ GoldenBlackHawk Part 60: Fight the Oppression, Man | 9:12 |
34. | Snack Time Sports | 58 | Channel Update (6/6/18) - Returning from Hiatus | 10:20 |
35. | Operating System Gaming | 56 | I'm Back With A Win | The Binding Of Isaac: After Birth Plus / Let's Play Part 53 | 49:17 |
36. | TheClownsAreThere | 55 | The Binding of Isaac 365 day #55, Get Gished, 720p HD (WITH COMMENTARY) | 28:13 |
37. | p-rich | 53 | Binding of Isaac Daily June 6, 2025 | 0:00 |
38. | F̴r̶a̵n̸k̶ ̴C̴a̷v̷e̴s̷ | 51 | 🔴Good Morning Part 64 | 37:26 |
39. | RodPotatoPie | 49 | The Binding of Isaac Pt. 50 - A challenging challenge! | 26:56 |
40. | Dinklez | 49 | "Good" at The Binding of Isaac: Maternity War | 0:00 |
41. | ChorbySP | 48 | Binding of Isaac - Episode 48: Just One Of Those Days | 49:15 |
42. | Hutts | 46 | 🧠🧠Third Save File Eden Post-it💩💩Late night chats with Edmund McMillen🤯🤯St. Jude Play Live (!StJude) | 4:56:04 |
43. | Oglala | 44 | The Binding of Isaac | 0:00 |
44. | Magicaleye | 44 | Isaac Original Run? | 17:49 |
45. | FratFerno | 44 | Let's Try The Binding of Isaac: Eternal Edition - Part 3 | 7:31 |
46. | CarlPlayin42 | 42 | The Binding of Isaac Unspoiled First Playthrough [Ep. 42] // Spin to Win | 0:00 |
47. | Deadhand | 42 | Deadhand Plays A Wizard's Lizard - Episode 12 | 24:44 |
48. | Sunburned Albino | 42 | OG Binding of Isaac, 9 Years Later | 10:09 |
49. | La cueva de Cexx | 40 | The Binding of Isaac REPETANCE #4 // Directo 6-4-2021 | 2:19:07 |
50. | Quinny | 39 | THE BINDING OF ISAAC CO-OP UPDATE IS HERE AT LAST.. | 0:00 |
51. | AppleByte | 38 | Applebye Plays: Binding of Isaac [Welcome Back] Part 38 | 25:23 |
52. | osumariokartman | 38 | Samson Gambles with His Life! = Isaac Daily Run #100 | 46:46 |
53. | KönchokTW | 38 | Channel Update | December 2014 | 8:14 |
54. | Chris is WaRcHiLdv1 | 36 | Binding of Isaac Pt37 I Suck Soooo Bad | 26:31 |
55. | Babbleplay | 35 | Binding Of Isaac Wrath of the Lamb 7 - Heavy Artillery (I Like Missiles) | 20:28 |
56. | Nova | 35 | The Binding Of Isaac: Wrath Of The Lamb Ep.31: FACING OFF WITH MOM AGAIN | 14:41 |
57. | chaosmastermind | 34 | The Binding of Isaac: Wrath of the Lamb: Ep.33 | 18:32 |
58. | Bingo | 33 | What's In The Basement?!!? | 0:00 |
59. | Ayumu Kagami | 33 | Icy | Ep. 8 | The Binding of Isaac Revalations Ch. 2 | 21:06 |
60. | Tealaian | 32 | Let's play Isaac! (Streaming through laptop for now) | 16:23 |
61. | Praisedscooter | 32 | Let's Play The Binding of Isaac pt29 - Goodbye, Isaac - finale | 9:34 |
62. | The Taculars | 31 | The Binding of Isaac: Quest for Mega Satan (Day 6!) | 0:00 |
63. | Fransnicolai | 30 | Binding of Isaac: 2nd Deadgod runs | 0:00 |
64. | QQHHGaming | 30 | The Binding of Isaac, Part 28 | 1:41:40 |
65. | Meesterman | 30 | The Binding of Isaac Nuzlocke Redux - [Ep 26] Wallstreet | 54:06 |
66. | Jabroni Mike Full Streams | 30 | The Binding of Isaac - 07/04/19 - Jabroni Mike Full Streams | 2:21:12 |
67. | Hands On Gaming | 29 | The Binding of Isaac Gameplay Action & Moments Series: Part 29 | 3:41 |
68. | PentaHybrid | 29 | Ranking Isaac's Books | 19:52 |
69. | Shake The Box Gaming | 28 | The Binding of Isaac: Online Co Op 19 - R KEY ALL DAY | 0:00 |
70. | SmallsGaming | 28 | The Binding of Isaac #28 I beat Isaac with Cain | 39:49 |
71. | bdLP | 28 | The Binding of Isaac Nuzlocke Season 2: Modlocke Trailer | 1:22 |
72. | Twisted Banana Productions | 27 | The Binding of Isaac Daily Challenge #30 Green neon lazer party | 59:21 |
73. | TheOwlHat | 27 | TheOwlHat Plays! The Binding Of Isaac Episode 127: Challenged | 21:07 |
74. | Julia's Landfill of Dreams | 26 | Laser Finale - [The Forgotten] The Binding of Isaac - (Episode 28) | 55:04 |
75. | CrabdaddyLonglegs | 26 | The Guardian - The Binding of Isaac | 2:33:10 |
76. | Jman37X | 26 | Gish 15th Anniversary: E4 - Hehenna Sisters | 21:08 |
77. | Half-Hearted Living | 26 | The Binding of Isaac: 1001% is never gonna happen | 2:23:39 |
78. | Eman-san | 26 | The Binding of Eman 26: The Dice (Finale) | 2:00:33 |
79. | Bloodina | 25 | Fuel to the G-Max. Binding of Isaac | 1:00:40 |
80. | SmixyRooster | 24 | The Binding of Isaac-Ep23-Dieing Left'n'Right | 9:54 |
81. | Richard Hammer | 24 | The Binding of Isaac and TFT 6/21/2024 | 4:07:47 |
82. | will309productions | 24 | Lets Play The Binding Of Issac Eps.44 | 12:58 |
83. | Hellbent | 24 | The Binding of Isaac - Online CO-OP | 2:09:38 |
84. | MineBorder | 23 | The Binding of Isaac Daily Challenge 5/26/16 We have made it to victory | 37:34 |
85. | Magdel | 23 | binding of isaac | 3:46:02 |
86. | MageSeal | 23 | Isaac Online Multiplayer Makes Me Question My Sanity... | 8:27 |
87. | rwm8558 | 23 | Let's Play - The Binding of Isaac - Episode 20 - Wrath of the Lamb | 31:17 |
88. | Mr.Jackthedemon | 23 | the binding of isaac Trying to get boss rush for the forgotten! | 1:05:27 |
89. | Nikc-Nack | 23 | Wrath of the Lamb (The Binding of Isaac) - Life 3 (HD) | 3:47 |
90. | Sayora | 22 | The Binding of Isaac! BACKA- BACKWARDS CHALLENGE! | 20:07 |
91. | Basement Dweller | 22 | The Binding of Isaac Four Souls- Anniversary Booster Pack Review! | 0:00 |
92. | Team Nova (Dog armada) | 22 | Binding of isaac episode 42 - Eve of fails | 26:52 |
93. | Astrial | 22 | 🤬 You Do NOT Have Permission To Swag Out! 🤬 | 1:07:01 |
94. | CloudyAmorous | 22 | Another BoI comp because I ran out of space again | 16:08 |
95. | X3hh | 22 | binding of isaac treasure room | 0:00 |
96. | REDEAREDBANDIT | 22 | The Binding Of Isaac's Easiest Boss | 1:23 |
97. | Ledeas Oakenbough | 22 | Binding of Isaac: Daily Feb 7th, 2018 | 1:01:47 |
98. | thenardsofdoom | 21 | The Binding of Isaac with Nazo episode 21: Rich Boy | 7:28 |
99. | FFiYWSC | 21 | The Binding of Isaac: Wrath of the Lamb - Gameplay w/Commentary Part 21 "I Dun Goofed" | 12:46 |
100. | Nick AR | 20 | Stream Ends When I Platinum The Binding of Isaac | 0:00 |