A physician wishes to prepare a buffer solution at \( \mathrm{pH}=3...

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A physician wishes to prepare a buffer solution at \( \mathrm{pH}=3.85 \) that efficiently resists changes in \( \mathrm{pH} \) yet contains only small concentration of the buffering
\( \mathrm{P} \) agents. Which of the following weak acids together with its sodium salt would be best to use?
(a) 2,5-Dihydroxybenzoic acid ( \( \left.\mathrm{p} K_{a}=2.97\right) \)
(b) Acetoacetic acid \( \left(\mathrm{p} K_{a}=3.58\right) \)
(c) \( m \)-Chlorobenzoic acid \( \left(\mathrm{p} K_{a}=3.98\right) \)
(d) \( p \)-Chlorocinnamic acid \( \left(\mathrm{p} K_{a}=4.41\right) \)
(1997)
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