Des-gamma carboxyprothrombin
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0Des-gamma carboxyprothrombin (DCP), also known as protein induced by vitamin K absence/antagonist-II (PIVKA-II), is an abnormal form of the coagulation protein, prothrombin. Normally, the prothrombin precursor undergoes post-translational carboxylation (addition of a carboxylic acid group) by gamma-glutamyl carboxylase in the liver prior to secretion into plasma. DCP/PIVKA-II may be detected in people with deficiency of vitamin K (due to poor nutrition or malabsorption) and in those taking warfarin or other medication that inhibits the action of vitamin K.
Source: https://en.wikipedia.org/wiki/Des-gamma_carboxyprothrombin
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Tags:
Acenocoumarol
Alphafetoprotein
Bloodplasma
Carboxylation
Carboxylicacid
Cirrhosis
Coagulation
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