My Sister’s Keeper (2004) by Jodi Picoult follows 13-year-old Anna Fitzgerald, who was conceived to be a donor for her sister, Kate, who suffers from leukemia. When Anna refuses to donate a kidney, she seeks medical emancipation with the help of lawyer Campbell Alexander. As the case unfolds, the family struggles with the emotional toll of Kate’s illness, the pressures on their other child Jesse, and the moral and legal dilemmas surrounding Anna’s choice. In a courtroom hearing, Anna wins her petition, but a tragic car accident leaves her brain-dead, and her kidney is donated to Kate. The story explores themes of family, sacrifice, autonomy, and grief, and was adapted into a 2009 film directed by Nick Cassavetes, starring Cameron Diaz and Abigail Breslin.
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