The Binding of Isaac: Repentance - Part 101 - T. Lazarus vs. Mother
This is probably one of the craziest starts I've ever had, mostly due to my own cockiness with Magic Skin. I may have acquired 4 broken hearts, but I also got Rock Bottom! I would've kept Eternal D6, but both characters HAD to hold Magic Skin, otherwise it would replace basically every item because of how much I used it. Rock Bottom isn't an instant win normally, but I got very lucky with Ipecac, and the rest of the run was history! I once again had a weaker dead Lazarus, but this time he wasn't that bad, and was able to hold his own pretty well throughout the entire run, while alive Lazarus got insane combos that were dangerous to his own health. Literally. I was so scared of taking too much damage in the final fight that I decided to just go for the weaker one, especially since I had the Drowsy pill, which makes the Mother fight free.
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