Which of the following statements is/are correct about Adenosine Deaminase (ADA) deficiency? I. I...

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Which of the following statements is/are correct about Adenosine Deaminase (ADA) deficiency?
I. In the absense of adenosine deaminase enzyme, purine metabolism is disturbed and erythrocytes fail to function.
II. ADA deficiency is caused by the deletion of the gene for ADA.
III. ADA patients can be permanently cured by bone marrow transplantation and enzyme replacement therapy.
IV. For permanent cure, the genes isolated from the bone marrow cells producing ADA is introduced into cells at early embryonic stages and replaced with faulty genes.
(a) I, II and III
(b) II and IV
(c) I, III and IV
(d) None of these

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