| 1. | The Binding of Isaac Rebirth - Super OP Breaking Run (E51) | 499 | | The Binding of Isaac: Rebirth
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| 2. | Channel Update: Isaac? | 316 | | The Binding of Isaac: Rebirth
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| 3. | The Binding of Isaac: Rebirth Episode 1 - Amazing | 284 | Show | The Binding of Isaac: Rebirth
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| 4. | The Binding of Isaac Afterbirth: Most Overpowered Run Yet (E6 - Breaking) | 228 | | The Binding of Isaac: Rebirth
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| 5. | The Binding of Isaac: Rebirth Episode 2 - Carry | 209 | | The Binding of Isaac: Rebirth
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| 6. | The Binding of Isaac: Rebirth Episode 3 - Cursed? | 140 | | The Binding of Isaac: Rebirth
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| 7. | The Binding of Isaac: Afterbirth - Greed Mode Top Secret Room Glitch | 121 | | The Binding of Isaac: Rebirth
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| 8. | The Binding of Isaac - Afterbirth: All of the lasers! | 121 | | The Binding of Isaac: Rebirth
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| 9. | The Binding of Isaac Rebirth Episode 13 - Clear | 112 | Show | The Binding of Isaac: Rebirth
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| 10. | The Binding of Isaac Rebirth: Episode 6 - Nerfed (But Still OP) | 111 | | The Binding of Isaac: Rebirth
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| 11. | The Binding of Isaac Rebirth: Episode 4 - Return Fire | 110 | | The Binding of Isaac: Rebirth
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| 12. | The Binding of Isaac Rebirth: Episode 19 - Michael Bay | 107 | Show | The Binding of Isaac: Rebirth
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| 13. | The Binding of Isaac Rebirth: Episode 20 - Speed | 103 | Show | The Binding of Isaac: Rebirth
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| 14. | The Binding of Isaac Rebirth: Episode 10 - Skip | 100 | Show | The Binding of Isaac: Rebirth
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| 15. | The Binding of Isaac: AFTERBIRTH+ - Episode 1 [Delirious] | 97 | | The Binding of Isaac: Rebirth
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| 16. | The Binding of Isaac Rebirth: Episode 25 - Patience | 96 | Show | The Binding of Isaac: Rebirth
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| 17. | The Binding of Isaac: Afterbirth - There is always one... | 95 | | The Binding of Isaac: Rebirth
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| 18. | The Binding of Isaac Rebirth: Episode 24 - Repeat | 95 | Show | The Binding of Isaac: Rebirth
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| 19. | The Binding of Isaac Rebirth - All of the Tears! (60 FPS test) | 94 | | The Binding of Isaac: Rebirth
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| 20. | The Binding of Isaac Rebirth - Sonic Glitch | 93 | | The Binding of Isaac: Rebirth
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| 21. | The Binding of Isaac Rebirth: Episode 15 - Unnecessary | 93 | Show | The Binding of Isaac: Rebirth
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| 22. | The Binding of Isaac Rebirth: Episode 33 - Saved | 88 | Show | The Binding of Isaac: Rebirth
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| 23. | The Binding of Isaac Rebirth: Episode 30 - Protected | 88 | Show | The Binding of Isaac: Rebirth
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| 24. | The Binding of Isaac Rebirth: Episode 26 - Jump | 86 | Show | The Binding of Isaac: Rebirth
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| 25. | The Binding of Isaac Rebirth: Episode 7 - Resurrection | 86 | Show | The Binding of Isaac: Rebirth
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| 26. | The Binding of Isaac Rebirth: Episode 8 - Hearty | 86 | Show | The Binding of Isaac: Rebirth
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| 27. | The Binding of Isaac Rebirth: Episode 14 - Tetrahedron | 85 | Show | The Binding of Isaac: Rebirth
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| 28. | MrIwont4get Streams Isaac - GG | 85 | | The Binding of Isaac: Rebirth
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| 29. | The Binding of Isaac Rebirth: Episode 12 - Bad | 83 | Show | The Binding of Isaac: Rebirth
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| 30. | The Binding of Isaac Rebirth: Episode 27 - Shade | 83 | Show | The Binding of Isaac: Rebirth
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| 31. | The Binding of Isaac Rebirth: Episode 29 - Sarcasm | 82 | Show | The Binding of Isaac: Rebirth
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| 32. | The Binding of Isaac Afterbirth: Episode 1 - Additional | 81 | | The Binding of Isaac: Rebirth
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| 33. | The Binding of Isaac Rebirth: Episode 17 - Regret | 81 | Show | The Binding of Isaac: Rebirth
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| 34. | The Binding of Isaac Rebirth: Episode 28 - Dwelling | 81 | Show | The Binding of Isaac: Rebirth
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| 35. | MrIwont4get Streams Isaac - Hubris | 80 | | The Binding of Isaac: Rebirth
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| 36. | The Binding of Isaac Rebirth: Episode 37 - Work | 80 | Show | The Binding of Isaac: Rebirth
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| 37. | The Binding of Isaac Rebirth: Episode 34 - Touch | 79 | Show | The Binding of Isaac: Rebirth
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| 38. | The Binding of Isaac Rebirth: Episode 11 - Two | 79 | Show | The Binding of Isaac: Rebirth
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| 39. | The Binding of Isaac Rebirth: Episode 39 - Dearth | 79 | Show | The Binding of Isaac: Rebirth
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| 40. | The Binding of Isaac Afterbirth: Episode 13 - Lucky | 78 | | The Binding of Isaac: Rebirth
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| 41. | The Binding of Isaac Rebirth: Episode 22 - Denied | 78 | Show | The Binding of Isaac: Rebirth
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| 42. | The Binding of Isaac Rebirth: Episode 31 - Biased | 76 | Show | The Binding of Isaac: Rebirth
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| 43. | The Binding of Isaac Rebirth: Episode 35 - Lazarith | 75 | Show | The Binding of Isaac: Rebirth
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| 44. | MrIwont4get Streams Isaac - Redemption | 74 | | The Binding of Isaac: Rebirth
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| 45. | The Binding of Isaac Rebirth: Episode 18 - Science! | 73 | Show | The Binding of Isaac: Rebirth
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| 46. | The Binding of Isaac Rebirth: Episode 16 - Lacking | 73 | Show | The Binding of Isaac: Rebirth
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| 47. | The Binding of Isaac Rebirth: Episode 9 - Stab | 73 | Show | The Binding of Isaac: Rebirth
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| 48. | MrIwont4get Streams Isaac - Positive | 73 | | The Binding of Isaac: Rebirth
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| 49. | The Binding of Isaac Rebirth: Episode 36 - Incomplete | 71 | Show | The Binding of Isaac: Rebirth
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| 50. | The Binding of Isaac Rebirth: Episode 5 - Bandage | 71 | | The Binding of Isaac: Rebirth
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| 51. | The Binding of Isaac Rebirth: Episode 47 - Slide | 71 | Show | The Binding of Isaac: Rebirth
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| 52. | The Binding of Isaac Rebirth: Episode 32 - Drop | 70 | Show | The Binding of Isaac: Rebirth
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| 53. | The Binding of Isaac Rebirth: Episode 59 - Firework | 70 | | The Binding of Isaac: Rebirth
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| 54. | The Binding of Isaac Rebirth: Episode 45 - Unknown | 68 | Show | The Binding of Isaac: Rebirth
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| 55. | The Binding of Isaac Rebirth: Episode 21 - Double | 65 | Show | The Binding of Isaac: Rebirth
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| 56. | The Binding of Isaac Rebirth: Episode 53 - Pizza | 64 | Show | The Binding of Isaac: Rebirth
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| 57. | The Binding of Isaac Rebirth: Episode 43 - Distraction | 64 | Show | The Binding of Isaac: Rebirth
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| 58. | The Binding of Isaac Rebirth: Episode 48 - Run | 64 | Show | The Binding of Isaac: Rebirth
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| 59. | The Binding of Isaac Afterbirth: Episode 5 - Bill | 62 | | The Binding of Isaac: Rebirth
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| 60. | The Binding of Isaac Rebirth: Episode 23 - Sudden | 62 | Show | The Binding of Isaac: Rebirth
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| 61. | The Binding of Isaac Rebirth: Episode 52 - Return | 62 | Show | The Binding of Isaac: Rebirth
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| 62. | The Binding of Isaac Afterbirth: Episode 7 - Persist (Breaking) | 61 | | The Binding of Isaac: Rebirth
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| 63. | The Binding of Isaac Rebirth: Episode 44 - Tears | 60 | Show | The Binding of Isaac: Rebirth
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| 64. | The Binding of Isaac Afterbirth: Episode 8 - Cursor | 60 | | The Binding of Isaac: Rebirth
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| 65. | The Binding of Isaac Afterbirth: Episode 11 - Altruistic (Breaking) | 59 | | The Binding of Isaac: Rebirth
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| 66. | The Binding of Isaac Rebirth: Episode 64 - Breaking | 58 | | The Binding of Isaac: Rebirth
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| 67. | The Binding of Isaac Rebirth: Episode 40 - Intelligent | 58 | Show | The Binding of Isaac: Rebirth
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| 68. | The Binding of Isaac Rebirth: Episode 38 - Slow | 58 | Show | The Binding of Isaac: Rebirth
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| 69. | The Binding of Isaac Rebirth: Episode 41 - Unyielding | 56 | Show | The Binding of Isaac: Rebirth
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| 70. | The Binding of Isaac: AFTERBIRTH+ - Episode 2 [Apollyon] | 55 | | The Binding of Isaac: Rebirth
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| 71. | The Binding of Isaac Rebirth: Episode 54 - Give | 53 | Show | The Binding of Isaac: Rebirth
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| 72. | The Binding of Isaac Afterbirth: Episode 2 - Maw | 52 | | The Binding of Isaac: Rebirth
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| 73. | The Binding of Isaac Afterbirth - Greed Mode | 52 | | The Binding of Isaac: Rebirth
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| 74. | The Binding of Isaac Afterbirth: Episode 24 - Neo | 52 | | The Binding of Isaac: Rebirth
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| 75. | The Binding of Isaac Rebirth: Episode 56 - Gilded | 52 | | The Binding of Isaac: Rebirth
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| 76. | The Binding of Isaac Afterbirth: Episode 12 - Signs | 51 | | The Binding of Isaac: Rebirth
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| 77. | The Binding of Isaac Rebirth: Episode 58 - Blind | 51 | | The Binding of Isaac: Rebirth
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| 78. | The Binding of Isaac Rebirth: Episode 55 - Delay | 51 | | The Binding of Isaac: Rebirth
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| 79. | The Binding of Isaac Afterbirth: Episode 3 - Disconnected | 51 | | The Binding of Isaac: Rebirth
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| 80. | The Binding of Isaac Afterbirth: Episode 10 - Percent | 50 | | The Binding of Isaac: Rebirth
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| 81. | The Binding of Isaac Rebirth: Episode 57 - Lost | 50 | | The Binding of Isaac: Rebirth
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| 82. | The Binding of Isaac Rebirth: Episode 61 - Panic | 50 | | The Binding of Isaac: Rebirth
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| 83. | The Binding of Isaac Afterbirth: Episode 27 - Implausible | 49 | | The Binding of Isaac: Rebirth
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| 84. | The Binding of Isaac Rebirth: Episode 60 - Vision | 49 | | The Binding of Isaac: Rebirth
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| 85. | The Binding of Isaac Rebirth: Episode 42 - Technically | 49 | Show | The Binding of Isaac: Rebirth
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| 86. | The Binding of Isaac Rebirth: Episode 50 - Ended | 49 | Show | The Binding of Isaac: Rebirth
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| 87. | The Binding of Isaac Afterbirth: Episode 15 - Behead | 49 | | The Binding of Isaac: Rebirth
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| 88. | He's Back! - The Binding of Isaac: Afterbirth+ #18 | 49 | | The Binding of Isaac: Rebirth
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| 89. | The Binding of Isaac Afterbirth: Episode 14 - Incendiary (Breaking) | 48 | | The Binding of Isaac: Rebirth
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| 90. | The Binding of Isaac: AFTERBIRTH+ - Episode 3 [Patched - Breaking] | 48 | | The Binding of Isaac: Rebirth
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| 91. | The Binding of Isaac Afterbirth: Episode 28 - Suction (Breaking) | 48 | | The Binding of Isaac: Rebirth
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| 92. | The Binding of Isaac Rebirth: Episode 62 - Destroyer | 48 | | The Binding of Isaac: Rebirth
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| 93. | The Binding of Isaac Afterbirth: Episode 19 - Miniscule | 48 | | The Binding of Isaac: Rebirth
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| 94. | The Binding of Isaac Afterbirth: Episode 9 - Impending | 47 | | The Binding of Isaac: Rebirth
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| 95. | The Binding of Isaac Afterbirth: Episode 4 - Down | 47 | | The Binding of Isaac: Rebirth
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| 96. | The Binding of Isaac Afterbirth: Episode 23 - Reoccur (Breaking) | 47 | | The Binding of Isaac: Rebirth
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| 97. | The Binding of Isaac Afterbirth: Episode 21 - Nutshell | 46 | | The Binding of Isaac: Rebirth
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| 98. | The Binding of Isaac Afterbirth: Episode 31 - Molar | 45 | | The Binding of Isaac: Rebirth
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| 99. | The Binding of Isaac Afterbirth: Episode 25 - Wave | 45 | | The Binding of Isaac: Rebirth
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| 100. | The Binding of Isaac Rebirth: Episode 46 - Missed | 45 | Show | The Binding of Isaac: Rebirth
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