| 301. | Jeremi Suri: History of American Power | Lex Fridman Podcast #180 | 949 | Show |
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| 302. | Joe Rogan and Lex Fridman at UFC 279 | 949 | |
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| 303. | Eric Weinstein's Harvard Story - The System Breaks Down in Novel Situations | AI Podcast Clips | 947 | Show |
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| 304. | Glenn Loury: Race, Racism, Identity Politics, and Cancel Culture | Lex Fridman Podcast #285 | 930 | Show |
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| 305. | Eugenia Kuyda: Friendship with an AI Companion | Lex Fridman Podcast #121 | 918 | Show |
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| 306. | Lisa Randall: Dark Matter, Theoretical Physics, and Extinction Events | Lex Fridman Podcast #403 | 915 | Show |
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| 307. | Steve Viscelli: Trucking and the Decline of the American Dream | Lex Fridman Podcast #237 | 908 | Show | The American Dream
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| 308. | Philip Goff: Consciousness, Panpsychism, and the Philosophy of Mind | Lex Fridman Podcast #261 | 903 | Show |
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| 309. | Brendan Eich: JavaScript, Firefox, Mozilla, and Brave | Lex Fridman Podcast #160 | 896 | Show |
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| 310. | How to learn and master a new skill | 893 | |
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| 311. | Bryan Johnson: Kernel Brain-Computer Interfaces | Lex Fridman Podcast #186 | 891 | Show |
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| 312. | Harvey Silverglate: Freedom of Speech | Lex Fridman Podcast #377 | 888 | Show |
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| 313. | Yannis Pappas: History and Comedy | Lex Fridman Podcast #175 | 878 | Show |
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| 314. | Take Back MIT | Eric Weinstein and Lex Fridman | 872 | Show |
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| 315. | Cal Newport: Deep Work, Focus, Productivity, Email, and Social Media | Lex Fridman Podcast #166 | 870 | Show |
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| 316. | Lex Fridman: Ask Me Anything - AMA January 2021 | Lex Fridman Podcast | 857 | Show |
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| 317. | Ginni Rometty: IBM CEO on Leadership, Power, and Adversity | Lex Fridman Podcast #362 | 850 | Show |
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| 318. | Deep Learning Basics: Introduction and Overview | 839 | |
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| 319. | Ian Hutchinson: Nuclear Fusion, Plasma Physics, and Religion | Lex Fridman Podcast #112 | 839 | Show |
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| 320. | Noam Chomsky: Language, Cognition, and Deep Learning | Lex Fridman Podcast #53 | 837 | |
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| 321. | Stephen Kotkin: Stalin's Rise to Power | AI Podcast Clips | 836 | Show |
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| 322. | Zev Weinstein: The Next Generation of Big Ideas and Brave Minds | Lex Fridman Podcast #158 | 833 | Show |
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| 323. | Michio Kaku: No Computer Can Simulate the Universe Except the Universe Itself | AI Podcast Clips | 830 | Show |
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| 324. | Whitney Cummings: Comedy, Robotics, Neurology, and Love | Lex Fridman Podcast #55 | 827 | |
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| 325. | Jiu Jitsu Meme Review with Ryan Hall | 825 | Review |
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| 326. | DeepMind solves protein folding | AlphaFold 2 | 824 | Let's Play |
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| 327. | Roger Gracie: Greatest Jiu Jitsu Competitor of All Time | Lex Fridman Podcast #343 | 818 | Show |
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| 328. | Grant Sanderson: 3Blue1Brown and the Beauty of Mathematics | Lex Fridman Podcast #64 | 791 | |
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| 329. | Manolis Kellis: Human Genome and Evolutionary Dynamics | Lex Fridman Podcast #113 | 790 | Show |
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| 330. | Paul Krugman: Economics of Innovation, Automation, Safety Nets & UBI | Lex Fridman Podcast #67 | 780 | Show |
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| 331. | Elon Musk Meme Review | 765 | Review |
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| 332. | The biggest chess game ever | 759 | |
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| 333. | Cumrun Vafa: String Theory | Lex Fridman Podcast #204 | 754 | Show |
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| 334. | Dan Reynolds: Imagine Dragons | Lex Fridman Podcast #290 | 747 | Show |
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| 335. | Elon Musk recap | Live Q&A with Lex Fridman | 740 | |
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| 336. | Kate Darling: Social Robots, Ethics, Privacy and the Future of MIT | Lex Fridman Podcast #329 | 729 | Show |
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| 337. | Richard Craib: WallStreetBets, Numerai, and the Future of Stock Trading | Lex Fridman Podcast #159 | 724 | Show |
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| 338. | Peter Wang: Python and the Source Code of Humans, Computers, and Reality | Lex Fridman Podcast #250 | 722 | Show |
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| 339. | Rick Doblin: Psychedelics | Lex Fridman Podcast #202 | 719 | Show |
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| 340. | Sean Carroll: Is There Intelligent Life Out There in the Universe? | AI Podcast Clips | 719 | Show |
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| 341. | Matt Walker: Sleep | Lex Fridman Podcast #210 | 712 | Show |
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| 342. | Aravind Srinivas: Perplexity CEO on Future of AI, Search & the Internet | Lex Fridman Podcast #434 | 710 | Show | Perplexity
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| 343. | Grant Sanderson (3Blue1Brown): Is Math Discovered or Invented? | AI Podcast Clips | 699 | Show |
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| 344. | James Gosling: Java, JVM, Emacs, and the Early Days of Computing | Lex Fridman Podcast #126 | 692 | Show |
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| 345. | Deep Learning State of the Art (2020) | 691 | |
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| 346. | Rana el Kaliouby: Emotion AI, Social Robots, and Self-Driving Cars | Lex Fridman Podcast #322 | 683 | Show |
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| 347. | Will Javascript Take Over the World? | Brian Kernighan and Lex Fridman | 681 | Show |
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| 348. | GPT-3 vs Human Brain | 667 | |
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| 349. | Kimbal Musk: The Art of Cooking, Tesla, SpaceX, Zip2, and Family | Lex Fridman Podcast #417 | 660 | Show |
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| 350. | Chris Lattner: Future of Programming and AI | Lex Fridman Podcast #381 | 660 | Show |
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| 351. | MIT 6.S094: Introduction to Deep Learning and Self-Driving Cars | 654 | |
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| 352. | In Memory of My Grandmother | 649 | |
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| 353. | Comma.ai Drive and Tour with George Hotz and Lex Fridman | 642 | |
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| 354. | Anya Fernald: Regenerative Farming and the Art of Cooking Meat | Lex Fridman Podcast #203 | 637 | Show |
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| 355. | Jim Keller: Elon Musk and Tesla Autopilot | AI Podcast Clips | 636 | Show |
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| 356. | Rob Reid: The Existential Threat of Engineered Viruses and Lab Leaks | Lex Fridman Podcast #193 | 632 | Show |
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| 357. | Josh Barnett: Philosophy of Violence, Power, and the Martial Arts | Lex Fridman #165 | 630 | Show |
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| 358. | Pixel 6 AI explained | Lex Fridman | 628 | |
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| 359. | Tyler Cowen: Economic Growth & the Fight Against Conformity & Mediocrity | Lex Fridman Podcast #174 | 626 | Show |
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| 360. | Training for David Goggins - 4x4x48 Challenge | Lex Fridman | 624 | |
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| 361. | Robert Crews: Afghanistan, Taliban, Bin Laden, and War in the Middle East | Lex Fridman Podcast #244 | 621 | Show |
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| 362. | Yann LeCun: Dark Matter of Intelligence and Self-Supervised Learning | Lex Fridman Podcast #258 | 619 | Show |
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| 363. | Jonathan Reisman: The Human Body - From Sex & Sperm to Hands & Heart | Lex Fridman Podcast #297 | 619 | Show |
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| 364. | Kelsi Sheren: War, Artillery, PTSD, and Love | Lex Fridman Podcast #230 | 615 | Show |
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| 365. | Jeffrey Shainline: Neuromorphic Computing and Optoelectronic Intelligence | Lex Fridman Podcast #225 | 612 | Show |
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| 366. | Brian Kernighan: UNIX, C, AWK, AMPL, and Go Programming | Lex Fridman Podcast #109 | 610 | Show |
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| 367. | Manolis Kellis: Meaning of Life, the Universe, and Everything | Lex Fridman Podcast #142 | 609 | Show |
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| 368. | Chris Lattner: The Future of Computing and Programming Languages | Lex Fridman Podcast #131 | 608 | Show |
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| 369. | Charan Ranganath: Human Memory, Imagination, Deja Vu, and False Memories | Lex Fridman Podcast #430 | 598 | Show |
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| 370. | Niels Jorgensen: New York Firefighters and the Heroes of 9/11 | Lex Fridman Podcast #220 | 585 | Show |
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| 371. | Impostor Syndrome - Pave Your Own Path | AMA #4 - Ask Me Anything with Lex Fridman | 578 | |
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| 372. | Max Tegmark: Life 3.0 | Lex Fridman Podcast #1 | 569 | |
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| 373. | 2+2=5 in Java | 552 | |
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| 374. | Ilya Sutskever: Deep Learning | Lex Fridman Podcast #94 | 537 | Show |
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| 375. | Christof Koch: Consciousness | Lex Fridman Podcast #2 | 537 | |
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| 376. | Ray Dalio: Principles, the Economic Machine, AI & the Arc of Life | Lex Fridman Podcast #54 | 535 | |
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| 377. | Michio Kaku: What Would Aliens Look Like? | AI Podcast Clips | 530 | Show |
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| 378. | Jeff Hawkins: Thousand Brains Theory of Intelligence | Lex Fridman Podcast #25 | 529 | |
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| 379. | Craig Jones: Jiu Jitsu, $2 Million Prize, CJI, ADCC, Ukraine & Trolling | Lex Fridman Podcast #439 | 524 | |
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| 380. | Alex Garland: Ex Machina, Devs, Annihilation, and the Poetry of Science | Lex Fridman Podcast #77 | 519 | Show |
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| 381. | Tony Fadell: iPhone, iPod, Nest, Steve Jobs, Design, and Engineering | Lex Fridman Podcast #294 | 513 | Show |
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| 382. | Moore's Law is Not Dead (Jim Keller) | AI Podcast Clips | 511 | Show |
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| 383. | Turing Test: Can Machines Think? | 502 | |
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| 384. | Scott Aaronson: Computational Complexity and Consciousness | Lex Fridman Podcast #130 | 502 | Show |
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| 385. | Sean Carroll: Many-Worlds Interpretation of Quantum Mechanics | 501 | Show |
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| 386. | Noam Brown: AI vs Humans in Poker and Games of Strategic Negotiation | Lex Fridman Podcast #344 | 501 | Show |
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| 387. | Ben Askren: Wrestling and MMA | Lex Fridman Podcast #242 | 494 | Show |
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| 388. | Michael Mina: Rapid Testing, Viruses, and the Engineering Mindset | Lex Fridman Podcast #146 | 494 | Show |
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| 389. | Wojciech Zaremba: OpenAI Codex, GPT-3, Robotics, and the Future of AI | Lex Fridman Podcast #215 | 491 | Show |
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| 390. | Self-replicating Python code | Quine | 487 | |
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| 391. | Programming Meme Review with George Hotz | 485 | Review |
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| 392. | Barry Barish: Gravitational Waves and the Most Precise Device Ever Built | Lex Fridman Podcast #213 | 483 | Show |
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| 393. | MIT Sloan: Intro to Machine Learning (in 360/VR) | 483 | |
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| 394. | Dan Gable: Olympic Wrestling, Mental Toughness & the Making of Champions | Lex Fridman Podcast #152 | 477 | Show |
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| 395. | Ryan Hall: Solving Martial Arts from First Principles | Lex Fridman Podcast #169 | 475 | Show |
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| 396. | Charles Isbell and Michael Littman: Machine Learning and Education | Lex Fridman Podcast #148 | 475 | Show |
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| 397. | Chris Duffin: The Mad Scientist of Strength | Lex Fridman Podcast #207 | 474 | Show |
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| 398. | Who is Hedgy? - A Story of Minimalism | AMA #5 - Ask Me Anything with Lex Fridman | 474 | |
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| 399. | Jeff Hawkins: The Thousand Brains Theory of Intelligence | Lex Fridman Podcast #208 | 473 | Show |
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| 400. | Peter Woit: Theories of Everything & Why String Theory is Not Even Wrong | Lex Fridman Podcast #246 | 472 | Show |
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