| 401. | Jim Keller: Most People Don't Think Simple Enough | AI Podcast Clips | 462 | Show |
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| 402. | Daniel Kahneman: Thinking Fast and Slow, Deep Learning, and AI | Lex Fridman Podcast #65 | 460 | |
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| 403. | Andrew Yang is Ahead of His Time - Kai-Fu Lee | AI Podcast Clips | 460 | Show |
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| 404. | Chris Blattman: War and Violence | Lex Fridman Podcast #273 | 457 | Show |
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| 405. | Andrew Ng: Deep Learning, Education, and Real-World AI | Lex Fridman Podcast #73 | 454 | Show |
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| 406. | Ronald Sullivan: The Ideal of Justice in the Face of Controversy and Evil | Lex Fridman Podcast #170 | 453 | Show |
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| 407. | David Silver: AlphaGo, AlphaZero, and Deep Reinforcement Learning | Lex Fridman Podcast #86 | 452 | Show |
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| 408. | Garry Kasparov: IBM Deep Blue, AlphaZero, and the Limits of AI in Open Systems | AI Podcast Clips | 449 | Show | Deep Blue
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| 409. | Jordan Jonas: Survival, Hunting, Siberia, God, and Winning Alone Season 6 | Lex Fridman Podcast #437 | 445 | Show |
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| 410. | The Way Out | Lex Fridman (Original) | 437 | |
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| 411. | Grant Sanderson: Math, Manim, Neural Networks & Teaching with 3Blue1Brown | Lex Fridman Podcast #118 | 436 | Show |
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| 412. | Make Disadvantage Your Superpower | Lex Fridman | AMA #6 | 434 | |
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| 413. | Lisa Feldman Barrett: Love, Evolution, and the Human Brain | Lex Fridman Podcast #140 | 428 | Show |
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| 414. | David Goggins 48 Hour Challenge - 4 Miles Every 4 Hours | Lex Fridman | 425 | |
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| 415. | Lex Fridman plays chess with Demis Hassabis | 424 | |
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| 416. | Lex Fridman Podcast | Now in ASCII + Name Change | 423 | Show |
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| 417. | Noam Chomsky: Meaning of Life | 423 | Show |
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| 418. | 7 Levels of Coronavirus Attack on Our Society and How We Can Fight Back | 414 | |
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| 419. | Kevin Systrom: Instagram | Lex Fridman Podcast #243 | 413 | Show |
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| 420. | Po-Shen Loh: Mathematics, Math Olympiad, Combinatorics & Contact Tracing | Lex Fridman Podcast #183 | 409 | Show |
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| 421. | DeepMind cube | 409 | |
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| 422. | David Eagleman: Neuroplasticity and the Livewired Brain | Lex Fridman Podcast #119 | 408 | Show |
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| 423. | Donald Knuth: Algorithms, Complexity, and The Art of Computer Programming | Lex Fridman Podcast #62 | 407 | |
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| 424. | Peter Singer: Suffering in Humans, Animals, and AI | Lex Fridman Podcast #107 | 404 | Show |
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| 425. | Travis Oliphant: NumPy, SciPy, Anaconda, Python & Scientific Programming | Lex Fridman Podcast #224 | 398 | Show |
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| 426. | Jordan Ellenberg: Mathematics of High-Dimensional Shapes and Geometries | Lex Fridman Podcast #190 | 397 | Show |
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| 427. | Happiness is a cookie that your brain bakes for itself (Joscha Bach) | AI Podcast Clips | 396 | Show |
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| 428. | Elon Musk: What's Outside the Simulation? | AI Podcast Clips | 394 | Show |
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| 429. | Steven Pinker: AI in the Age of Reason | Lex Fridman Podcast #3 | 390 | |
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| 430. | Edward Gibson: Human Language, Psycholinguistics, Syntax, Grammar & LLMs | Lex Fridman Podcast #426 | 390 | Show |
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| 431. | Marc Raibert: Boston Dynamics and the Future of Robotics | Lex Fridman Podcast #412 | 386 | Show |
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| 432. | Gilbert Strang: Linear Algebra, Teaching, and MIT OpenCourseWare | Lex Fridman Podcast #52 | 386 | |
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| 433. | Scott Aaronson: Quantum Computing | Lex Fridman Podcast #72 | 386 | Show |
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| 434. | Elon Musk Makes Sense to Me (Eric Weinstein) | AI Podcast Clips | 382 | Show |
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| 435. | Kai-Fu Lee: AI Superpowers - China and Silicon Valley | Lex Fridman Podcast #27 | 379 | |
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| 436. | Manolis Kellis: Biology of Disease | Lex Fridman Podcast #133 | 378 | Show |
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| 437. | Erik Brynjolfsson: Economics of AI, Social Networks, and Technology | Lex Fridman Podcast #141 | 367 | Show |
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| 438. | Oriol Vinyals: Deep Learning and Artificial General Intelligence | Lex Fridman Podcast #306 | 363 | Show |
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| 439. | Charles Isbell: Computing, Interactive AI, and Race in America | Lex Fridman Podcast #135 | 363 | Show |
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| 440. | Sean Carroll: The Nature of the Universe, Life, and Intelligence | Lex Fridman Podcast #26 | 361 | |
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| 441. | Karl Friston: Neuroscience and the Free Energy Principle | Lex Fridman Podcast #99 | 361 | Show |
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| 442. | Richard Dawkins: The Programmer of the Simulation Came About Through Evolution | AI Podcast Clips | 360 | Show |
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| 443. | Self-Driving Cars: State of the Art (2019) | 359 | |
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| 444. | Time Lapse of the Sun (1 second is 1 month) | 354 | |
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| 445. | Lee Smolin: Quantum Gravity and Einstein's Unfinished Revolution | Lex Fridman Podcast #79 | 353 | Show |
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| 446. | Ryan Schiller: Librex and the Free Exchange of Ideas on College Campuses | Lex Fridman Podcast #172 | 339 | Show |
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| 447. | Donald Knuth: Programming, Algorithms, Hard Problems & the Game of Life | Lex Fridman Podcast #219 | 339 | Show |
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| 448. | Lex Fridman does judo with Travis Stevens, Olympic Silver Medalist | 337 | |
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| 449. | Best hidden feature of Python | Chaining comparison operators | 331 | |
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| 450. | 10 things I'm grateful for this Thanksgiving | 328 | |
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| 451. | Jo Boaler: How to Learn Math | Lex Fridman Podcast #226 | 327 | Show |
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| 452. | Ray Kurzweil: Future of Intelligence | MIT 6.S099: Artificial General Intelligence (AGI) | 319 | Show |
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| 453. | Harry Cliff: Particle Physics and the Large Hadron Collider | Lex Fridman Podcast #92 | 317 | Show |
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| 454. | Best feature of Python | List Comprehensions | 315 | |
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| 455. | Elon Musk: Consciousness | 312 | Show |
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| 456. | Do Something Difficult Every Day | AMA #1 - Ask Me Anything with Lex Fridman | 311 | |
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| 457. | Risto Miikkulainen: Neuroevolution and Evolutionary Computation | Lex Fridman Podcast #177 | 309 | Show |
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| 458. | Dan Kokotov: Speech Recognition with AI and Humans | Lex Fridman Podcast #151 | 308 | Show |
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| 459. | Guido van Rossum: Python | Lex Fridman Podcast #6 | 302 | |
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| 460. | Most Research in Deep Learning is a Total Waste of Time - Jeremy Howard | AI Podcast Clips | 302 | Show |
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| 461. | Skye Fitzgerald: Hunger, War, and Human Suffering | Lex Fridman Podcast #278 | 299 | Show |
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| 462. | François Chollet: Measures of Intelligence | Lex Fridman Podcast #120 | 298 | Show |
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| 463. | Kate Darling: Social Robotics | Lex Fridman Podcast #98 | 291 | Show |
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| 464. | Dmitry Korkin: Evolution of Proteins, Viruses, Life, and AI | Lex Fridman Podcast #153 | 286 | Show |
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| 465. | Travis Stevens: Judo, Olympics, and Mental Toughness | Lex Fridman Podcast #223 | 282 | Show |
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| 466. | Cristiano Amon: Qualcomm CEO | Lex Fridman Podcast #280 | 280 | Show |
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| 467. | Dmitri Dolgov: Waymo and the Future of Self-Driving Cars | Lex Fridman Podcast #147 | 279 | Show |
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| 468. | Sleep and Burnout | AMA #2 - Ask Me Anything with Lex Fridman | 276 | |
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| 469. | Michael I. Jordan: Machine Learning, Recommender Systems, and Future of AI | Lex Fridman Podcast #74 | 267 | Show |
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| 470. | Toward a Fundamental Theory of Physics (Stephen Wolfram) | AI Podcast Clips | 265 | Show |
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| 471. | Gilbert Strang: Linear Algebra vs Calculus | 264 | Show |
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| 472. | If You Could Live Forever Would You? (Ben Goertzel) | AI Podcast Clips with Lex Fridman | 263 | Show |
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| 473. | Jed Buchwald: Isaac Newton and the Philosophy of Science | Lex Fridman Podcast #214 | 258 | Show |
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| 474. | Greg Brockman: OpenAI and AGI | Lex Fridman Podcast #17 | 255 | |
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| 475. | Elon Musk: Pale Blue Dot and Beyond | 255 | Show |
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| 476. | Exponential Progress of AI: Moore's Law, Bitter Lesson, and the Future of Computation | 251 | |
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| 477. | Douglas Lenat: Cyc and the Quest to Solve Common Sense Reasoning in AI | Lex Fridman Podcast #221 | 251 | Show |
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| 478. | David Chalmers: What is Consciousness? | AI Podcast Clips | 250 | Show |
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| 479. | Stephen Schwarzman: Going Big in Business, Investing, and AI | Lex Fridman Podcast #96 | 248 | Show |
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| 480. | David Patterson: Computer Architecture and Data Storage | Lex Fridman Podcast #104 | 247 | Show |
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| 481. | Are We Living in a Simulation? with George Hotz and Lex Fridman | AI Podcast Clips | 246 | Show |
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| 482. | Ryan Hall: Principles of Jiu Jitsu | Take It Uneasy Podcast | 241 | Show |
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| 483. | Judea Pearl: Causal Reasoning, Counterfactuals, and the Path to AGI | Lex Fridman Podcast #56 | 241 | |
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| 484. | Juergen Schmidhuber: Godel Machines, Meta-Learning, and LSTMs | Lex Fridman Podcast #11 | 241 | |
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| 485. | When will the 200 billionth person be born? | 239 | |
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| 486. | Dealing with Negative Comments | AMA #3 - Ask Me Anything with Lex Fridman | 237 | |
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| 487. | Ian Goodfellow: Generative Adversarial Networks (GANs) | Lex Fridman Podcast #19 | 236 | |
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| 488. | Ishan Misra: Self-Supervised Deep Learning in Computer Vision | Lex Fridman Podcast #206 | 230 | Show |
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| 489. | C Programming Language | Brian Kernighan and Lex Fridman | 227 | Show |
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| 490. | Luís and João Batalha: Fermat's Library and the Art of Studying Papers | Lex Fridman Podcast #209 | 224 | Show |
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| 491. | Zach Bitter: Ultramarathon Running | Lex Fridman Podcast #205 | 222 | Show |
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| 492. | John Clarke: The Art of Fighting and the Pursuit of Excellence | Lex Fridman Podcast #143 | 221 | Show |
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| 493. | Michael Littman: Reinforcement Learning and the Future of AI | Lex Fridman Podcast #144 | 220 | Show |
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| 494. | Dileep George: Brain-Inspired AI | Lex Fridman Podcast #115 | 219 | Show |
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| 495. | Stuart Russell: Long-Term Future of Artificial Intelligence | Lex Fridman Podcast #9 | 219 | |
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| 496. | Escaping the Local Optimum of Low Expectation | 216 | |
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| 497. | Cristos Goodrow: YouTube Algorithm | Lex Fridman Podcast #68 | 215 | Show |
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| 498. | Rodney Brooks: Robotics | Lex Fridman Podcast #217 | 213 | Show |
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| 499. | Michael Mina: Rapid COVID Testing | Lex Fridman Podcast #235 | 213 | Show |
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| 500. | Michio Kaku: Would Aliens Destroy Us? | AI Podcast Clips | 212 | Show |
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