Top 100 The Binding of Isaac: Rebirth Videos With The Most Comments by Nick ARTop 100 » 200 » 300 » 400 » 500Video TitleCommentsCategoryGame1.OP Method To Beat Greedier Mode As The Lost!113The Binding of Isaac: Rebirth 2.This Combo Packs A Real Punch!25The Binding of Isaac: Rebirth 3.Jacob & Esau DESTROY Mega Satan!23The Binding of Isaac: Rebirth 4.What Having EVERY Bomb Item Looks Like...20The Binding of Isaac: Rebirth 5.Infinite Money & Stats Farm In Isaac!16The Binding of Isaac: Rebirth 6.Why You Should Always Check Secret Rooms!11The Binding of Isaac: Rebirth Top 100 » 200 » 300 » 400 » 500