| 201. | Venom is back with Message To Mcjuggernuggets | 74 | |
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| 202. | Venom is Mean | 73 | |
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| 203. | He is Mad At Traci Hines | 73 | |
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| 204. | The Last Stand Trailer # 3 | 72 | Preview |
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| 205. | Spider-Man's Web # 2 | 72 | |
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| 206. | To The Haters | 71 | |
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| 207. | Spider-Man(Joe Isaacson) Vs Venom Star Wars Edition | 71 | |
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| 208. | For @theHacksmith | 71 | |
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| 209. | Its My Birthday Son!!!! | 71 | |
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| 210. | Bar Fight | 70 | |
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| 211. | The Last Stand Trailer # 1 | 70 | Preview |
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| 212. | Joe's Reacts To SPELLFURY Season One (Episodes 1-12) | 70 | |
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| 213. | They Need Me | 69 | |
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| 214. | gangnamstyle | 68 | |
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| 215. | I Like Jacksepticeye feat The Gregory Brothers All the Way I Believe In Steve | 68 | |
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| 216. | Spirngwood Slasher Vs The Webslinger 2 Feat Venom | 68 | |
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| 217. | New Spider-Man Clip The HEIST | 67 | |
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| 218. | Joe isaacson at wizard world comic con in Minneapolis | 67 | |
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| 219. | Big Announcement | 66 | |
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| 220. | I'm still single it sucks man | 65 | |
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| 221. | Hitler still hate Doc Ock | 65 | |
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| 222. | Message To Maria Kanellis | 65 | |
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| 223. | Happy Holidays From Me And The Joe Isaacson Films | 64 | |
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| 224. | I Wont Back Down | 64 | |
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| 225. | Joe Isaacson Meets Selena Gomez | 64 | |
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| 226. | Meeting Noir Spider-man | 64 | |
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| 227. | RE:Traci Hines as The Little Mermaid | 63 | | The Little Mermaid
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| 228. | Spider-Man Talks About Mickie James | 63 | |
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| 229. | Rip Stan Lee | 63 | |
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| 230. | #hellboy | 63 | |
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| 231. | Joe Reacts To Evil Clown | 63 | |
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| 232. | The Wavy Tube Man Chronicles | 62 | |
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| 233. | New Spider-Man Clip The Lost | 62 | |
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| 234. | Darth Vader Vs Kylo Ren Teaser | 61 | |
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| 235. | Lightsaber Test 2 | 61 | |
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| 236. | Message to Lady Gaga | 59 | |
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| 237. | THE WOLVERINE (Fan Made Trailer) | 59 | |
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| 238. | I'm Sorry Traci Hines | 58 | |
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| 239. | To Princess Rapunzel | 58 | |
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| 240. | The Shocker Voiceover | 58 | |
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| 241. | Story Time with Alex final Battle | 57 | |
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| 242. | Death by piano | 57 | |
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| 243. | New Spider-man Final Traller | 56 | |
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| 244. | Overwatch Play Of The Game: Joe Isaacson | 56 | | Overwatch 2
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| 245. | Joe's Driving School | 56 | |
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| 246. | My Story About Me Cosplaying | 56 | |
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| 247. | Joe Knocked Out Chucky | 55 | |
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| 248. | Joe Isaacson Saw Ariel and The Sea Witch in Once Upon a Time | 55 | |
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| 249. | For Our Fallen Brothers Lets Play Resident Evil 5 Part 2 | 55 | Let's Play | Resident Evil 5
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| 250. | Joe Isaacson's First Blog | 55 | |
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| 251. | Joe is Angerly Thinking | 55 | |
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| 252. | Zombie Crawl Live | 55 | |
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| 253. | Batman The Killing Joke Scene Remaster | 53 | | Batman: Arkham City
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| 254. | Joe Vs Ben After Math | 53 | |
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| 255. | For Our Fallen Brothers Lets Play Resident Evil 5 Part 3 (Bonus Story) | 53 | Let's Play | Resident Evil 5
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| 256. | Slipping Into Friendship Feat: Spider-Man | 52 | |
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| 257. | Thank you From Joe Isaacson | 52 | |
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| 258. | Rise Above from Spider-Man Turn Off The Dark | 52 | |
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| 259. | We will miss you Ashley Massaro blog | 52 | |
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| 260. | Disney's Find Your Voice ( I Am Spider-Man) | 50 | |
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| 261. | The Best Emperor Palpatine Ever | 48 | Let's Play |
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| 262. | Lightsaber Test 3 | 48 | |
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| 263. | Spider-man-Theme | 48 | |
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| 264. | Episode 1 trailer | 48 | Preview |
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| 265. | Joe Isaacson Reacts To WONDER WOMAN vs WOLVERINE Made By BatInTheSun | 48 | |
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| 266. | A Message To My Fans, Youtubers,Facebook, Twitter, And Google+ | 48 | |
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| 267. | Let Play Spider-Man : Web Of Shadows Part 2 | 48 | | Spider-Man: Web of Shadows
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| 268. | Joe Isaacson Interviews Spider-Man | 47 | |
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| 269. | The Aftermath from the Snowball Final Battle Spider-Man vs Venom | 46 | |
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| 270. | Zombie Crawl Live 2 | 46 | |
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| 271. | The Last Stand Trailer # 2 | 46 | |
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| 272. | for Traci Hines | 44 | |
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| 273. | Me As Spider-man | 44 | |
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| 274. | Message to Lady Gaga Yet Again | 44 | |
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| 275. | To Late | 43 | |
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| 276. | Age Of Heroes Mep | 43 | |
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| 277. | Despicable Me 2- Another Villain New Doc Ock | 42 | |
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| 278. | Who Am I Gonna Be For Halloween | 42 | |
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| 279. | Hipster Mermaid Theme | 42 | |
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| 280. | Rolling Glory Trailer | 42 | Preview |
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| 281. | Your friendly neighborhood Joe Isaacson Lets Play Marvel‘s Spider-Man Part 1 | 41 | Let's Play | Spider-Man
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| 282. | Meet my Roommate Venom | 41 | |
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| 283. | Spider-man mask Details | 41 | |
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| 284. | Meet The Casual Friday Spider-man | 40 | |
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| 285. | Frank 'D Amico KO BY Joe Isaacson | 40 | |
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| 286. | For a love a pete | 40 | |
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| 287. | Joe Isaacson's Film Contest (Open) | 39 | |
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| 288. | There's My Pals Mep | 39 | |
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| 289. | I'm Going to Kansas city Comic Con and a New Spider-Man Fan Film | 39 | |
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| 290. | Stuck as Vader Again | 38 | |
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| 291. | He is coming back. | 38 | |
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| 292. | Meet Arkham Asylum version of Bane | 38 | |
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| 293. | MAN UP 2 Lets Play Resident Evil 8 Part final | 38 | Let's Play | Resident Evil Village
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| 294. | Joe And The Doctor Save The Day | 37 | |
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| 295. | He's back vlog | 37 | |
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| 296. | The Spectacular Spider Man Cast Recruitment | 36 | |
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| 297. | Christmas vlog | 36 | Vlog |
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| 298. | AJ Lee Interuppt Joe Isaacson Yet a Again | 36 | |
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| 299. | Spider Man's Bio | 36 | |
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| 300. | Joe Isaacson React To A Spider-Man Fan Film #dharmannstudios #featurethis #spiderman | 36 | |
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