| 301. | Fool's Gold - FIEND FOLIO Trinket Guide - The Binding of Isaac Mod | 5:06 | Guide | The Binding of Isaac: Rebirth
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| 302. | Little Chubby - Item Guide - The Binding of Isaac: Rebirth | 5:05 | Guide | The Binding of Isaac: Rebirth
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| 303. | Prayer Card - Item Guide - The Binding of Isaac: Rebirth | 5:04 | Guide | The Binding of Isaac: Rebirth
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| 304. | Supermagnetic Ludovico! - Viewer Synergies #4 (SlayXc2) | 5:04 | | The Binding of Isaac: Rebirth
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| 305. | Occult Storm Cloud! - Viewer Synergies #3 (SlayXc2) | 5:04 | Show | The Binding of Isaac: Rebirth
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| 306. | Is this the last Secret of Repentance? Or just a Bug? | 5:04 | | The Binding of Isaac: Rebirth
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| 307. | Double Brainstone? - Viewer Synergies #30 (SlayXc2) | 5:04 | | The Binding of Isaac: Rebirth
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| 308. | The Maelstrom! - Viewer Synergies #29 (SlayXc2) | 5:03 | | The Binding of Isaac: Rebirth
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| 309. | Little Gish - Item Guide - The Binding of Isaac: Rebirth | 5:03 | Guide | The Binding of Isaac: Rebirth
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| 310. | The Orbit of Death! - Viewer Synergies #23 (SlayXc2) | 5:02 | | The Binding of Isaac: Rebirth
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| 311. | Mr. Mega - Item Guide - The Binding of Isaac: Rebirth | 5:02 | Guide | The Binding of Isaac: Rebirth
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| 312. | Ouija Board - Item Guide - The Binding of Isaac: Rebirth | 5:01 | Guide | The Binding of Isaac: Rebirth
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| 313. | 5 easy/fun Ways to kill "MOTHER"! The Binding of Isaac Repentance | 5:00 | | The Binding of Isaac: Rebirth
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| 314. | 5 easy/fun Ways to kill HUSH! The Binding of Isaac Repentance | 5:00 | | The Binding of Isaac: Rebirth
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| 315. | A Pony - Item Guide - The Binding of Isaac: Rebirth | 5:00 | Guide | The Binding of Isaac: Rebirth
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| 316. | Chili Powder - FIEND FOLIO Trinket Guide - The Binding of Isaac Mod | 5:00 | Guide | The Binding of Isaac: Rebirth
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| 317. | NEW Synergy in Patch 1.7.8! Brimstone + Soy Milk + Anti-Gravity | 5:00 | | The Binding of Isaac: Rebirth
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| 318. | You can break this Item in multiple Ways! (Sanguine Bond Guide) | 5:00 | Guide | The Binding of Isaac: Rebirth
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| 319. | Become A Poop Bender! - Viewer Synergies #14 (SlayXc2) | 5:00 | | The Binding of Isaac: Rebirth
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| 320. | When The Bloat Gets Promoted! - The Mancer (Mod Showcase) | 5:00 | Show | The Binding of Isaac: Rebirth
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| 321. | 5 easy/fun Ways to kill The Beast! The Binding of Isaac Repentance | 5:00 | | The Binding of Isaac: Rebirth
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| 322. | 5 easy/fun Ways to kill Delirium! The Binding of Isaac Repentance | 5:00 | | The Binding of Isaac: Rebirth
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| 323. | X-Ray Vision - Item Guide - The Binding of Isaac: Rebirth | 5:00 | Guide | The Binding of Isaac: Rebirth
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| 324. | This NEW Rewind Glitch Breaks The Succubus Item! | 4:58 | | The Binding of Isaac: Rebirth
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| 325. | Forever Alone - Item Guide - The Binding of Isaac: Rebirth | 4:58 | Guide | The Binding of Isaac: Rebirth
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| 326. | The Swarm - Item Guide - The Binding of Isaac: Repentance | 4:58 | Guide | The Binding of Isaac: Rebirth
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| 327. | My Little Unicorn - Item Guide - The Binding of Isaac: Rebirth | 4:57 | Guide | The Binding of Isaac: Rebirth
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| 328. | How much LUCK do the Infinite Loops need now? (C Section + Technology) | 4:57 | | The Binding of Isaac: Rebirth
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| 329. | Psytosis! - Viewer Synergies #25 (SlayXc2) | 4:57 | | The Binding of Isaac: Rebirth
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| 330. | Risk's Reward - Psionic Reroll! (Fiend Folio) | 4:57 | | The Binding of Isaac: Rebirth
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| 331. | Eye Technology! 👀 (Isaac Synergy Showcase) | 4:56 | Vlog | The Binding of Isaac: Rebirth
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| 332. | Ring Cap - Trinket Guide - The Binding of Isaac: Repentance | 4:56 | Guide | The Binding of Isaac: Rebirth
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| 333. | The Poop Beggar!!! A Bomb Bum For Tainted-??? | 4:55 | | The Binding of Isaac: Rebirth
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| 334. | This Item Starts A Shady Side-Quest!!! (Fiend Folio) | 4:53 | | The Binding of Isaac: Rebirth
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| 335. | How to fuse with Dark Esau! (Tainted Jacob + Suplex) | 4:52 | | The Binding of Isaac: Rebirth
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| 336. | Tainted Diesaac - The walking Game Break! (Mod Showcase) | 4:52 | Show | The Binding of Isaac: Rebirth
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| 337. | The Ninja (Naruto) Item Build! - The Binding of Isaac: Repentance | 4:51 | | The Binding of Isaac: Rebirth
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| 338. | Death Certificate Is STILL BROKEN In Patch 1.7.9a!!! | 4:50 | | The Binding of Isaac: Rebirth
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| 339. | Broken Remote - Trinket Guide - The Binding of Isaac: Rebirth | 4:48 | Guide | The Binding of Isaac: Rebirth
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| 340. | Infestation - Item Guide - The Binding of Isaac: Rebirth | 4:47 | Guide | The Binding of Isaac: Rebirth
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| 341. | Use this Void Glitch for extra Stats! (Repentance) | 4:46 | | The Binding of Isaac: Rebirth
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| 342. | Lil Abaddon - Item Guide - The Binding of Isaac: Repentance | 4:46 | Guide | The Binding of Isaac: Rebirth
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| 343. | Spider Bite - Item Guide - The Binding of Isaac: Rebirth | 4:45 | Guide | The Binding of Isaac: Rebirth
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| 344. | BUFFED Voodoo Head - NEW Curse Room Layouts! | 4:45 | | The Binding of Isaac: Rebirth
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| 345. | Tooth And Nail Can Grant You A Free Win!!! | 4:44 | | The Binding of Isaac: Rebirth
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| 346. | Anarchist Cookbook - Item Guide - The Binding of Isaac: Rebirth | 4:44 | Guide | The Binding of Isaac: Rebirth
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| 347. | Old Capacitor - The misunderstood Trinket! | 4:44 | | The Binding of Isaac: Rebirth
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| 348. | Lil Chest - Item Guide - The Binding of Isaac: Afterbirth | 4:42 | Guide | The Binding of Isaac: Rebirth
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| 349. | Skatole - Item Guide - The Binding of Isaac: Rebirth | 4:41 | Guide | The Binding of Isaac: Rebirth
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| 350. | Fiend's Horn - FIEND FOLIO Item Guide - The Binding of Isaac Mod | 4:41 | Guide | The Binding of Isaac: Rebirth
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| 351. | Ultimate Zap Build! - Viewer Synergies #2 (SlayXc2) | 4:41 | Show | The Binding of Isaac: Rebirth
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| 352. | Charm of the Vampire - Item Guide - The Binding of Isaac: Rebirth | 4:41 | Guide | The Binding of Isaac: Rebirth
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| 353. | The Battery - Item Guide - The Binding of Isaac: Rebirth | 4:37 | Guide | The Binding of Isaac: Rebirth
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| 354. | Guardian Angel - Item Guide - The Binding of Isaac: Rebirth | 4:37 | Guide | The Binding of Isaac: Rebirth
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| 355. | The Book of Sin - Item Guide - The Binding of Isaac: Rebirth | 4:37 | Guide | The Binding of Isaac: Rebirth
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| 356. | 5 New Quality of Life Mods that you should use! (Repentance) | 4:37 | | The Binding of Isaac: Rebirth
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| 357. | Little Steven - Item Guide - The Binding of Isaac: Rebirth | 4:36 | Guide | The Binding of Isaac: Rebirth
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| 358. | Azazel's Rage - Item Guide - The Binding of Isaac: Repentance | 4:36 | Guide | The Binding of Isaac: Rebirth
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| 359. | This is what the D7 does to The Beast! (Isaac Repentance) | 4:35 | | The Binding of Isaac: Rebirth
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| 360. | Mom's Locket - Trinket Guide - The Binding of Isaac: Afterbirth | 4:34 | Guide | The Binding of Isaac: Rebirth
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| 361. | The Unbreakable Bone Shield! - Viewer Synergies #32 (SlayXc2) | 4:34 | | The Binding of Isaac: Rebirth
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| 362. | The Book of Belial - Item Guide - The Binding of Isaac: Rebirth | 4:33 | Guide | The Binding of Isaac: Rebirth
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| 363. | What happens if you void ALL active items? (Repentance) | 4:33 | | The Binding of Isaac: Rebirth
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| 364. | Echo Chamber + Ancient Recall (New Game Break) - The Binding of Isaac: Repentance | 4:33 | | The Binding of Isaac: Rebirth
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| 365. | Binge Eater - Item Guide - The Binding of Isaac: Repentance | 4:32 | Guide | The Binding of Isaac: Rebirth
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| 366. | Infinite Damage Stacking with Dark Arts/Tainted Judas! | 4:32 | | The Binding of Isaac: Rebirth
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| 367. | Cards in Repentance - What is New? What Has Changed? | 4:32 | | The Binding of Isaac: Rebirth
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| 368. | Notched Axe is a Powerhouse on Bethany! | 4:31 | | The Binding of Isaac: Rebirth
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| 369. | Cursed Penny - Trinket Guide - The Binding of Isaac: Repentance | 4:30 | Guide | The Binding of Isaac: Rebirth
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| 370. | Sacred Orb - Item Guide - The Binding of Isaac: Repentance | 4:30 | Guide | The Binding of Isaac: Rebirth
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| 371. | GMO Penny - FIEND FOLIO Trinket Guide - The Binding of Isaac Mod | 4:30 | Guide | The Binding of Isaac: Rebirth
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| 372. | Eternal Delirium - Repentance Eternal Edition (Mod) | 4:30 | | The Binding of Isaac: Rebirth
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| 373. | TAINTED Deleted - Character Showcase (Mod) - Isaac Repentance | 4:29 | | The Binding of Isaac: Rebirth
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| 374. | Rock Bottom + Ipecac is absolutely insane. | 4:27 | | The Binding of Isaac: Rebirth
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| 375. | Forgotten's Life and Death Break (Death Certificate + Birthright) | 4:26 | | The Binding of Isaac: Rebirth
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| 376. | New "Tainted" Enemies in Repentance! (Home/Ascent Path) | 4:22 | | The Binding of Isaac: Rebirth
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| 377. | Eternal Ultra Greed(ier) - Repentance Eternal Edition (Mod) | 4:22 | | The Binding of Isaac: Rebirth
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| 378. | Bloody Sandpaper - FIEND FOLIO Trinket Guide - The Binding of Isaac Mod | 4:21 | Guide | The Binding of Isaac: Rebirth
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| 379. | Fling to Win? TAINTED Bertran Explained! (Mod) | 4:20 | | The Binding of Isaac: Rebirth
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| 380. | Isaac Hawk's Pro Skater!!! | 4:20 | | The Binding of Isaac: Rebirth
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| 381. | 3 Cool NEW Bomb Items In Fiend Folio! | 4:20 | | The Binding of Isaac: Rebirth
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| 382. | Libra got Buffed! But how does it work? (Repentance Patch 1.7.8) | 4:20 | | The Binding of Isaac: Rebirth
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| 383. | Robo-Baby - Item Guide - The Binding of Isaac: Rebirth | 4:20 | Guide | The Binding of Isaac: Rebirth
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| 384. | Ace of Spades - Trinket Guide - The Binding of Isaac: Rebirth | 4:20 | Guide | The Binding of Isaac: Rebirth
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| 385. | The Tech X NERF nobody talks about!? (Repentance) | 4:20 | | The Binding of Isaac: Rebirth
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| 386. | Which Tear is in the Air the longest? Isaac Range Contest! | 4:20 | | The Binding of Isaac: Rebirth
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| 387. | Super Easy Mode - Fiend Folio Mod - The Binding of Isaac Afterbirth+ | 4:20 | | The Binding of Isaac: Rebirth
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| 388. | Cricket's Head - Item Guide - The Binding of Isaac: Rebirth | 4:19 | Guide | The Binding of Isaac: Rebirth
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| 389. | Blood of the Martyr - Item Guide - The Binding of Isaac: Rebirth | 4:19 | Guide | The Binding of Isaac: Rebirth
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| 390. | Death Certificate... With A Twist! - Error's Crazy Slots (Fiend Folio) | 4:18 | | The Binding of Isaac: Rebirth
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| 391. | Steam Sale - Item Guide - The Binding of Isaac: Rebirth | 4:18 | Guide | The Binding of Isaac: Rebirth
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| 392. | The Nail - Item Guide - The Binding of Isaac: Rebirth | 4:17 | Guide | The Binding of Isaac: Rebirth
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| 393. | You can Break Forgotten with ONE Item! (Death Certificate + Forgotten) | 4:16 | | The Binding of Isaac: Rebirth
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| 394. | The Relic - Item Guide - The Binding of Isaac: Rebirth | 4:16 | Guide | The Binding of Isaac: Rebirth
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| 395. | Daddy Longlegs - Item Guide - The Binding of Isaac: Rebirth | 4:14 | Guide | The Binding of Isaac: Rebirth
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| 396. | 1UP! - Item Guide - The Binding of Isaac: Rebirth | 4:14 | Guide | The Binding of Isaac: Rebirth
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| 397. | You were misinformed about Dark Esau! (How Stage HP ACTUALLY work) | 4:12 | | The Binding of Isaac: Rebirth
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| 398. | Mother (Witness) - Boss Fight + Ending 21 - The Binding of Isaac: Repentance | 4:11 | | The Binding of Isaac: Rebirth
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| 399. | Deep Pockets got Buffed in Repentance? | 4:10 | | The Binding of Isaac: Rebirth
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| 400. | Isaac's Tomb - Item Guide - The Binding of Isaac: Repentance | 4:09 | Guide | The Binding of Isaac: Rebirth
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