| 301. | BONUS SARAH | Revelations | 3,221 | | The Binding of Isaac: Rebirth
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| 302. | Isaac Goes To The Future | 3,190 | | The Binding of Isaac: Rebirth
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| 303. | Fastest Gun In The Basement | 3,177 | | The Binding of Isaac: Rebirth
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| 304. | SAY CHEESE | 3,176 | | Inscryption
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| 305. | These New Bosses Almost Made Me Quit | 3,160 | |
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| 306. | Champion Judas Brimstone Madness | 3,144 | | The Binding of Isaac: Rebirth
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| 307. | Lord of The Flies | 3,143 | | The Binding of Isaac: Rebirth
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| 308. | THE SCARIEST BOSS SO FAR | 3,139 | | Inscryption
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| 309. | cat game good | 3,097 | | Stray
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| 310. | I Got Goblined In Stack Lands | 3,074 | | The Binding of Isaac: Rebirth
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| 311. | This King Baby Synergy Is Unique | 3,072 | | The Binding of Isaac: Rebirth
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| 312. | losing my mind in the binding of isaac | 3,066 | | The Binding of Isaac: Rebirth
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| 313. | Walking The Dog In Isaac | 3,061 | | The Binding of Isaac: Rebirth
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| 314. | Vampire Survivors Is A Bop | 3,055 | | Vampire Survivors
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| 315. | Evil Charm Is A Scam #bindingofisaac | 3,054 | | The Binding of Isaac: Rebirth
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| 316. | Best Characters In Isaac | 3,047 | | The Binding of Isaac: Rebirth
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| 317. | 20 Minutes Until Death | 3,008 | | Vampire Survivors
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| 318. | Playable Hush Is Better Than Ever | 2,990 | | The Binding of Isaac: Rebirth
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| 319. | KINETIC BLADE ONLY | FORTNITE | 2,986 | | Fortnite
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| 320. | Only Real Gamers Can Watch This Video | 2,979 | | Fortnite
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| 321. | Don't praise Lil Dumpy. #bindingofisaac | 2,970 | | The Binding of Isaac: Rebirth
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| 322. | The Long Drive or Something | 2,963 | | The Long Drive
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| 323. | Dome Keeping is My Passion | 2,955 | |
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| 324. | I Found The Thing | 2,890 | |
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| 325. | Local Magical Dog Terrorizes Children | 2,849 | | MultiVersus
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| 326. | This Boss Is A Nightmare | 2,839 | | The Binding of Isaac: Rebirth
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| 327. | the longest drive yet | 2,823 | | The Long Drive
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| 328. | A Maid Needs A Gun | 2,811 | | The Binding of Isaac: Rebirth
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| 329. | Every Item Is Crater Baby | 2,791 | |
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| 330. | This Challenge Made Me Play With 4 Characters | 2,790 | | The Binding of Isaac: Rebirth
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| 331. | Every Item Is... Uhhh | 2,760 | |
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| 332. | Champion Eve Made Me Panic | 2,745 | | The Binding of Isaac: Rebirth
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| 333. | THE POWER OF GOD AND ANIME | 2,732 | | Death Road to Canada
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| 334. | The Rotten Is Stinky | 2,713 | | The Binding of Isaac: Rebirth
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| 335. | This Character Smashes Everything | 2,710 | | The Binding of Isaac: Rebirth
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| 336. | This Character Has The Craziest Synergies | 2,657 | | The Binding of Isaac: Rebirth
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| 337. | This Apollyon Rework Is Something Else | 2,656 | | The Binding of Isaac: Rebirth
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| 338. | This Character Is Not Lucky | 2,644 | | The Binding of Isaac: Rebirth
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| 339. | This Synergy Ruined My Video | 2,592 | | The Binding of Isaac: Rebirth
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| 340. | Every Item Is Milk! | 2,588 | |
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| 341. | Toilet Chronicles or Something | 2,585 | | The Binding of Isaac: Rebirth
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| 342. | Vampire Survivors Is Too Spooky | 2,516 | | Vampire Survivors
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| 343. | Death Road to Death | 2,426 | | Death Road to Canada
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| 344. | Double The Hearts Double The Pain | 2,422 | | The Binding of Isaac: Rebirth
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| 345. | Tainted Gello Is Evolutionary | 2,409 | | The Binding of Isaac: Rebirth
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| 346. | This Character Can Only Dash | 2,373 | | The Binding of Isaac: Rebirth
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| 347. | Tainted Sin Certified Good Boy | 2,351 | | The Binding of Isaac: Rebirth
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| 348. | This NEW Character Is Groundbreaking | 2,324 | | The Binding of Isaac: Rebirth
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| 349. | This Character Can Spawn Any Room | 2,295 | | The Binding of Isaac: Rebirth
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| 350. | Easiest Rock Bottom Unlock Ever! | 2,265 | |
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| 351. | Every Item Is Wimpy Bro | 2,208 | |
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| 352. | This OLD Character Made Me Tryhard | 2,194 | | The Binding of Isaac: Rebirth
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| 353. | Isaac But I Start With A Diplopia D6 | 2,171 | | The Binding of Isaac: Rebirth
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| 354. | Swallow The Sea Is Spooky | 2,169 | |
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| 355. | Thank you | 1,000 Subscriber Celebration | 2,160 | |
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| 356. | dog game | 2,149 | |
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| 357. | When Life Gives You Pet Rock | 2,146 | |
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| 358. | The Darkest Isaac Mod LITERALLY | 2,123 | | The Binding of Isaac: Rebirth
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| 359. | Champion Isaac Is Dicey | 2,110 | | The Binding of Isaac: Rebirth
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| 360. | This Character Changes NOTHING | 2,101 | | The Binding of Isaac: Rebirth
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| 361. | I Became ALMOST Invincible | 2,094 | | The Binding of Isaac: Rebirth
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| 362. | Tainted Unbidden Nukes Everything | 2,091 | | The Binding of Isaac: Rebirth
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| 363. | They Put Gojo In Isaac | 2,021 | | The Binding of Isaac: Rebirth
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| 364. | This Epic Fetus Synergy Almost Crashed My Game | 1,997 | |
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| 365. | Genius Angel Strategy #gaming #bindingofisaac | 1,985 | | The Binding of Isaac: Rebirth
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| 366. | The Real Best Character In Isaac | 1,966 | | The Binding of Isaac: Rebirth
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| 367. | This New Isaac Mod Is Refreshing | 1,946 | | The Binding of Isaac: Rebirth
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| 368. | This Challenge Makes Tarnished Lost Unplayable | 1,942 | | The Binding of Isaac: Rebirth
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| 369. | This Character Cries Whirlpools | 1,930 | Let's Play | The Binding of Isaac: Rebirth
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| 370. | Fattest Gun In The Basement | 1,904 | | The Binding of Isaac: Rebirth
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| 371. | Just Regular Forgotten | 1,892 | | The Binding of Isaac: Rebirth
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| 372. | Tainted Sheriff Is Whippingly Good | 1,885 | | The Binding of Isaac: Rebirth
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| 373. | NEW Mega Bean Is Overpowered | 1,876 | |
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| 374. | When I Take Damage The Vampire Survivors-Like Game Changes | 1,865 | | Vampire Survivors
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| 375. | The Greenest Isaac Character | 1,845 | | The Binding of Isaac: Rebirth
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| 376. | I Waited Too Long To Play This Character | 1,812 | | The Binding of Isaac: Rebirth
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| 377. | I Didn't Wait Long Enough To Play This Character | 1,795 | | The Binding of Isaac: Rebirth
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| 378. | WORM BLAST!!! | 1,794 | | The Binding of Isaac: Rebirth
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| 379. | This Challenge Is Too Wild | 1,793 | | The Binding of Isaac: Rebirth
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| 380. | Go Play With The Neighbor's Kid... | 1,768 | | The Binding of Isaac: Rebirth
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| 381. | Lemon Damocles Carried My Run | 1,758 | | The Binding of Isaac: Rebirth
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| 382. | I Was FORCED To Play This Character | 1,752 | | The Binding of Isaac: Rebirth
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| 383. | EAT THE DAMN EGG | Stack Lands | 1,748 | |
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| 384. | This Challenge Is Slimy | 1,743 | | The Binding of Isaac: Rebirth
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| 385. | Isaac But Every Floor Is Random | 1,737 | | The Binding of Isaac: Rebirth
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| 386. | Isaac Online With RogueWatermelon | 1,727 | | The Binding of Isaac: Rebirth
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| 387. | AAAAAAAAAAAAAAAAAAAAAA | 1,722 | |
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| 388. | This NEW Character Is Very Hot | 1,713 | | The Binding of Isaac: Rebirth
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| 389. | Buckshot Roulette In Isaac | 1,702 | | The Binding of Isaac: Rebirth
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| 390. | This Character Can Use Every Active Item | 1,696 | | The Binding of Isaac: Rebirth
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| 391. | The ULTIMATE Planetarium Tier List (REAL) | 1,693 | |
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| 392. | Greedier is Fair and Balanced | 1,687 | |
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| 393. | When The Furniture Is Sus | 1,677 | | Perfect Vermin
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| 394. | The Onion Ring Run | 1,637 | | The Binding of Isaac: Rebirth
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| 395. | The Hungriest Isaac Character | 1,623 | | The Binding of Isaac: Rebirth
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| 396. | The Double Daddy Attack | 1,593 | | The Binding of Isaac: Rebirth
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| 397. | THERE IS ALWAYS A BIGGER CRAB | 1,587 | | Crab Champions
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| 398. | This Libra Combo Is Insane | 1,577 | |
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| 399. | This New Update Revamps The Mines | 1,561 | Vlog | The Binding of Isaac: Rebirth
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| 400. | Never Taunt The Horror Game Monster | 1,536 | |
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