| 301. | WHEEL OF CHILDREN! - #1083 | 1,291 | | The Binding of Isaac: Rebirth
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| 302. | Isaac Afterbirth Gameplay! - Show #1263 | 1,288 | | The Binding of Isaac: Rebirth
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| 303. | Ultimate Isaac Streak - #1140 | 1,285 | | The Binding of Isaac: Rebirth
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| 304. | Viewers Choice - Great Loss! | 1,281 | | The Binding of Isaac: Rebirth
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| 305. | (0-0) Blue Baby Streaking! - Show #1177 | 1,262 | Show | The Binding of Isaac: Rebirth
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| 306. | Viewers Choice Isaac- FTL No Pause - #1023 | 1,249 | | The Binding of Isaac: Rebirth
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| 307. | (13-0) Eden Streaking! - Show #1236 | 1,241 | Show | The Binding of Isaac: Rebirth
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| 308. | (9-0, Lilith) Isaac Afterbirth - Show #1221 | 1,221 | | The Binding of Isaac: Rebirth
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| 309. | FTL No Pause + Isaac #1025 | 1,217 | | The Binding of Isaac: Rebirth
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| 310. | (4-0, Lilith) Community Choice! - Show #1220 | 1,206 | Show | The Binding of Isaac: Rebirth
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| 311. | Daily + Timed SMB! - Show #1279 | 1,205 | Show | The Binding of Isaac: Rebirth
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| 312. | Tainted Lost / Jacob - [540/637 Secrets] - A Place to Enjoy Gaming - Show #2581 Part 1- [CC] | 1,193 | | The Binding of Isaac: Rebirth
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| 313. | Garden of Eden - #1081 | 1,188 | | The Binding of Isaac: Rebirth
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| 314. | The Binding of Eyesack - #1130 (P1) | 1,173 | | The Binding of Isaac: Rebirth
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| 315. | Isaac Mastery Streak - #1142 | 1,161 | | The Binding of Isaac: Rebirth
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| 316. | (4-0) Wheel of Children! - Show #1229 | 1,143 | | The Binding of Isaac: Rebirth
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| 317. | Chat Open Forever - Show #1233 | 1,138 | Show | The Binding of Isaac: Rebirth
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| 318. | Greedy Junkie Viewer Challenge | 1,127 | | The Binding of Isaac: Rebirth
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| 319. | Road to 110-0 #18 - Maggie Time! (Part 2/2) | 1,125 | | The Binding of Isaac: Rebirth
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| 320. | (3-0) Eden Streaks - Show #1185 | 1,119 | Show | The Binding of Isaac: Rebirth
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| 321. | (3-0) Eden Streaking! - Show #1182 | 1,115 | Show | The Binding of Isaac: Rebirth
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| 322. | Isaac Daily + FUN & GAMES! - Good Vibes - Show #1517 | 1,115 | | The Binding of Isaac: Rebirth
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| 323. | (17-0) - Eden Streaking! - Show #1237 (P1) | 1,112 | Show | The Binding of Isaac: Rebirth
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| 324. | (18-0, Lilith) Community Streak - Show #1223 | 1,111 | Show | The Binding of Isaac: Rebirth
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| 325. | Isaac Mastery - #1152 | 1,092 | | The Binding of Isaac: Rebirth
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| 326. | (23-0, Lilith) Community Streak - Show #1224 | 1,091 | Show | The Binding of Isaac: Rebirth
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| 327. | Isaac Mastery - #1147 | 1,091 | | The Binding of Isaac: Rebirth
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| 328. | Isaac Gameplay - #1059 | 1,074 | | The Binding of Isaac: Rebirth
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| 329. | (0-0) Dark Room / Full Clears! - Show #1192 | 1,073 | Show | The Binding of Isaac: Rebirth
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| 330. | Isaac Gameplay - #1064 | 1,064 | | The Binding of Isaac: Rebirth
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| 331. | (32-0, Lilith) Isaac Afterbirth - Show #1226 | 1,047 | Show | The Binding of Isaac: Rebirth
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| 332. | BIRTHDAY STREAM! - Eden Streaking (9-0) - Show #1188 | 1,038 | Show | The Binding of Isaac: Rebirth
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| 333. | No-Frills Entertainment & Relaxation - Show #1519 Part 2 | 1,035 | | The Binding of Isaac: Rebirth
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| 334. | (27-0, Lilith) Community Streak - Show #1225 | 1,031 | Show | The Binding of Isaac: Rebirth
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| 335. | Community Choice Streaking! Show #1219 (P2) | 1,019 | Show | The Binding of Isaac: Rebirth
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| 336. | Isaac Mastery Streak - #1146 | 1,015 | | The Binding of Isaac: Rebirth
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| 337. | Keeper time! Positivity breeds Positivity :) - Show #1216 (P2) | 968 | Show | The Binding of Isaac: Rebirth
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| 338. | Maggie Chest run - Blue Baby fight | 952 | | The Binding of Isaac: Rebirth
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| 339. | (0-0) Eden Streak! - Show #1180 | 944 | Show | The Binding of Isaac: Rebirth
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| 340. | Isaac Gameplay - #1047 | 943 | | The Binding of Isaac: Rebirth
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| 341. | (0-0) Mega Satan Streak! - New schedule! (7pm - 3am Pacific) - Show #1190 | 942 | Show | The Binding of Isaac: Rebirth
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| 342. | (32-0) Eden Streaking! - Show #1244 (P2) | 939 | Show | The Binding of Isaac: Rebirth
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| 343. | (32-0) Eden Streaking! - Show #1244 (P1) | 936 | Show | The Binding of Isaac: Rebirth
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| 344. | (6-0) Wheel of Children! - Show #1229 | 927 | Show | The Binding of Isaac: Rebirth
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| 345. | Isaac - #1125 (P1) | 911 | | The Binding of Isaac: Rebirth
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| 346. | Isaac Gameplay - #1049 | 907 | | The Binding of Isaac: Rebirth
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| 347. | Isaac Mastery - #1159 | 886 | | The Binding of Isaac: Rebirth
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| 348. | Road to 110-1 #9 - Cain run for Mom Kills (Part 2/2) | 882 | | The Binding of Isaac: Rebirth
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| 349. | Isaac Gameplay - #1060 | 882 | | The Binding of Isaac: Rebirth
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| 350. | The truest form of happiness is to be happy for others. - Show #1211 (P2) | 867 | Show | The Binding of Isaac: Rebirth
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| 351. | Binding of Eyesack - #1129 | 857 | | The Binding of Isaac: Rebirth
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| 352. | Gravity Ghost / Isaac - #1042 | 842 | | The Binding of Isaac: Rebirth
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| 353. | (3-0) Mega Satan Streak - New schedule! (7pm - 3am Pacific) - Show #1191 | 841 | | The Binding of Isaac: Rebirth
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| 354. | The Betrayer (Judas Streak 4) - #1110 (P2) | 825 | | The Binding of Isaac: Rebirth
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| 355. | (12-0, Lilith) Isaac Afterbirth - Show #1222 | 806 | | The Binding of Isaac: Rebirth
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| 356. | Isaac Mastery Streak - #1145 (P1) | 793 | | The Binding of Isaac: Rebirth
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| 357. | Seize the day! Final Lost Runs :) - Show #1218 (P3) | 786 | Show | The Binding of Isaac: Rebirth
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| 358. | (17-0) - Eden Streaking! - Show #1237 (P2) | 785 | Show | The Binding of Isaac: Rebirth
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| 359. | Road to 110-0 #15 - Fifth Cain Run for Polaroid (Part 2/2) | 767 | | The Binding of Isaac: Rebirth
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| 360. | No-Frills Entertainment & Relaxation - Show #1519 Part 1 | 752 | | The Binding of Isaac: Rebirth
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| 361. | Isaac - #1124 (P2) | 740 | | The Binding of Isaac: Rebirth
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| 362. | (6-0) Eden Streaking! - Show #1183 | 737 | | The Binding of Isaac: Rebirth
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| 363. | Judas Has No Soul (P1) | 736 | | The Binding of Isaac: Rebirth
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| 364. | Serious Time! (0-0) Eden Streaks - Show #1184 | 733 | Show | The Binding of Isaac: Rebirth
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| 365. | Viewer Challenge - Sub Choice (P2) | 721 | | The Binding of Isaac: Rebirth
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| 366. | 5 Years in Content Production! - Show #1249 (P1) | 688 | Show | The Binding of Isaac: Rebirth
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| 367. | (16-0, Lilith) Isaac Afterbirth - Show #1222 | 686 | Show | The Binding of Isaac: Rebirth
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| 368. | (11-0) Eden Streaking! - Show #1235 | 663 | Show | The Binding of Isaac: Rebirth
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| 369. | #997 - Isaac (2/3) | 663 | | The Binding of Isaac: Rebirth
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| 370. | Seize the day! Final Lost Runs :) - Show #1218 (P2) | 655 | Show | The Binding of Isaac: Rebirth
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| 371. | (7-0, Lilith) Community Choice! - Show #1220 | 639 | Show | The Binding of Isaac: Rebirth
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| 372. | Road to 110-0 #11 - First Cain Run for Polaroid (Part 2/2) | 638 | | The Binding of Isaac: Rebirth
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| 373. | Isaac Mastery Streak - #1145 (P3) | 603 | | The Binding of Isaac: Rebirth
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| 374. | Road to 110-0 #13 - Third Cain Run for Polaroid (Part 2/2) | 585 | | The Binding of Isaac: Rebirth
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| 375. | Isaac - #1125 (P2) | 576 | | The Binding of Isaac: Rebirth
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| 376. | Unsupervised Child in Basement - Show #1198 (P1) | 571 | Show | The Binding of Isaac: Rebirth
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| 377. | Isaac - #1124 (P3) | 534 | | The Binding of Isaac: Rebirth
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| 378. | Serious Time! (1-0) Eden Streaks - Show #1184 | 530 | | The Binding of Isaac: Rebirth
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| 379. | Afterbirth in 4 days! Let us have some fun :) - Show #1199 | 473 | Show | The Binding of Isaac: Rebirth
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| 380. | #1010 (Part 1) - Apotheon/Isaac | 455 | | The Binding of Isaac: Rebirth
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| 381. | Isaac Mastery Streak - #1145 (P2) | 446 | | The Binding of Isaac: Rebirth
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| 382. | (4-0) Dark Room / Full Clears - Show #1195 | 445 | | The Binding of Isaac: Rebirth
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| 383. | 2 Days Until Afterbirth (HYPE!) - Show #1201 | 427 | Show | The Binding of Isaac: Rebirth
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| 384. | (0-0) Dark Room / Full Clears - Isaac with a VENGEANCE! - Show #1194 | 418 | | The Binding of Isaac: Rebirth
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| 385. | Show #1200!! - Perfect Attendance :) - Never late / No Excuses | 406 | Show | The Binding of Isaac: Rebirth
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| 386. | Unsupervised Child in Basement - Show #1197 (P1) | 392 | Show | The Binding of Isaac: Rebirth
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| 387. | Unsupervised Child in Basement - Show #1197 (P2) | 335 | Show | The Binding of Isaac: Rebirth
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| 388. | Unsupervised Child in Basement - Show #1198 (P2) | 277 | Show | The Binding of Isaac: Rebirth
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| 389. | (3-0) Dark Room / Full Clears - Isaac with a VENGEANCE! - Show #1194 | 245 | | The Binding of Isaac: Rebirth
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| 390. | 5 Years in Content Production! - Show #1249 (P3) | 125 | Show | The Binding of Isaac: Rebirth
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